Search results for "Genou"
showing 10 items of 610 documents
Testimonios indígenas conosureños: ¿convivencias excluyentes?
2016
Resumen: El presente articulo, partiendo de lapremisa de que la teoria del testimonio en AmericaLatina fue construida a partir de textos testimonialesdel area centroamericana y caribena sobre la base deun trasfondo marxista, revisa de manera panoramicatestimonios de cuatro culturas indigenas deSudamerica (quechua, aymara, mapuche y yagan)resaltando la dimension cultural contenida en estos.Se caracterizan tanto las condiciones de produccionde estos testimonios como tambien las formas deconvivencia que estos representan. Las exclusionesque padecen los testimoniantes por parte de susrespectivas sociedades se interpretan comoconsecuencia de la idea ilustrada de progreso que guiola construccion …
Food products, gastronomy and religious tourism: The resilience of food landscapes
2021
Abstract Religious tourism has always been a sector of significant importance in the field of cultural tourism. Religious tourism is located both in urban areas and in rural areas. In rural areas in the past it did not represent a factor of great impact on the local economy as most of the population lived in rural areas. With the advent of modern society and with the phenomena of agricultural and rural exodus, linked to the increase in income in developed societies, religious tourism becomes a critical success factor for many rural areas as a historical heritage. This aspect is of significant importance if we consider that it can represent a real engine of development especially for rural a…
Enhancing the Endogenous Potential of Agricultural Landscapes: Strategies and Projects for a Inland Rural Region of Sicily
2018
This paper focuses on the potential of the rural landscape of Sicily, the largest island in the Mediterranean Sea, taking into particular account the critical need to deal with the problem of depopulation of the small inner areas by leveraging the “integrated exploitation” of local resources. The rural landscape is considered to be capable of playing an essential role in many fields: ecology, production, culture and tourism. In this regard, guidelines are set by the Sustainable Development Goals of the United Nations, the EU guidelines and the experience from Italy’s Rural Development Plans, the latter of which aim at achieving the much sought-after multi-functionality of agriculture. This …
Cultivation of algae with indigenous species – Potentials for regional biofuel production
2011
The massive need for sustainable energy has led to an increased interest in new energy resources, such as production of algae, for use as biofuel. There are advantages to using algae, for example, ...
Biochemical and chemical characterization of Cynara cardunculus L. extract and its potential use as co-adjuvant therapy of chronic myeloid leukemia
2017
Abstract Ethnopharmacological relevance Ancient mediterranean diet was characterized by consuming the spontaneous forms of Cynara cardunculus L. (CCL), commonly called artichoke. Cultivated and/or spontaneous forms of CC studies have demonstrated that methanol extract of CCL flower and/or cynaropicrin showed remarkable anti-proliferative activity in vitro models of leukocyte cancer cell. Aim of the study Chronic myeloid leukemia (CML) is associated with a reciprocal translocation of the long arms of chromosomes 9 and 22 generating the BCR/ABL fusion gene, translated in the p210 BCR/ABL oncoprotein kinase. This chimeric protein is the target of a kinase inhibitor, imatinib, but the developme…
Permeability changes of integrin-containing multivesicular structures triggered by picornavirus entry.
2014
Cellular uptake of clustered α2β1-integrin induces the formation of membrane compartments that subsequently mature into a multivesicular body (MVB). Enhanced internalization mediated by clustered integrins was observed upon infection by the picornavirus echovirus 1 (EVI). We elucidated the structural features of virus-induced MVBs (vMVBs) in comparison to antibody-induced control MVBs (mock infection) by means of high-pressure cryo fixation of cells followed by immuno electron tomography during early entry of the virus. Three-dimensional tomograms revealed a marked increase in the size and complexity of these vMVBs and the intraluminal vesicles (ILVs) at 2 and 3.5 hours post infection (p.i.…
An improved protocol for electroporation ofOenococcus oeniATCC BAA-1163 using ethanol as immediate membrane fluidizing agent
2008
Aims: To finalize an effective and reproducible electroporation procedure to transform Oenococcus oeni ATCC BAA-1163 strain. Methods and Results: The vector pGID052 was selected to optimize the electroporation procedure. Transformation efficiency was 5·8 × 103 per μg of DNA. Transformation was improved when competent cells were prepared with exponential phase cultures; optimum electroporation parameters were an electric pulse of 12·5 kV cm−1, under a resistance of 200 Ω and the presence of 10% (v/v) ethanol in the electroporation buffer (EPB). Conclusions: An effective protocol to transform O. oeni ATCC BAA-1163 strain by electroporation has been obtained by addition of ethanol to the EP…
Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognition.
2014
ABSTRACT The Mycobacterium tuberculosis genome includes the large family of pe_pgrs genes, whose functions are unknown. Because of precedents in other pathogens in which gene families showing high sequence variation are involved in antigenic variation, a similar role has been proposed for the pe_pgrs genes. However, the impact of immune selection on pe_pgrs genes has not been examined. Here, we sequenced 27 pe_pgrs genes in 94 clinical strains from five phylogenetic lineages of the M. tuberculosis complex (MTBC). We found that pe_pgrs genes were overall more diverse than the remainder of the MTBC genome, but individual members of the family varied widely in their nucleotide diversity and in…
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity
2004
Endothelin-1 (ET-1) is a 21-amino-acid peptide, derived from vascular endothelial cells, with potent vasoconstrictor activity. ET-1 has been implicated in diverse physiological or pathological processes, including the vascular changes associated with sepsis. However, the factors that regulate ET-1-associated toxicity during bacterial infections, or in other settings, are not fully understood. Both the pathology associated with certain allergic and autoimmune disorders, and optimal host defence against bacterial and parasitic infections are mediated by mast cells. In vitro, mast cells can produce ET-1 (ref. 11), undergo ET-1-dependent and endothelin-A receptor (ET(A))-dependent activation, a…
Fonti storiche e fonti numismatiche a confronto nella Sicilia centro-meridionale della fine del V sec. a.C.
2006
The historical events that involved Sicily at the end of the 5th century BC find a precise description in the X-XIII books of Diodorus Siculus. The numismatic testimonies from the territory of central-southern Sicily, in addition to confirming what has been illustrated by the historian of Agira, integrate and enrich the information, adding data for the same period relating above all to the indigenous centres, neglected by the sources.