Search results for "Genou"

Social networks : promoting Mexican popular cultures and building a participatory culture

2012

For over 30 years, the General Direction of Popular Cultures has been in charge of promoting, preserving, and disseminating the cultural diversity of Mexico, regarding indigenous and popular cultural practices. With the increasing popularization of Social Networks, it has become almost indispensable to join Social Networks in order to exist digitally, weather you are an individual, an institution or government. Taking this fact in consideration, in 2011 the Direction of Popular Cultures joined the most utilized social Networks in México: Twitter, Facebook and YouTube, as a way to keep users updated about the activities and general information generated by the Direction. Departing form the p…

Simultaneous sludge minimization, biological phosphorous removal and membrane fouling mitigation in a novel plant layout for MBR.

2020

Abstract The integration of one anaerobic reactor in the mainstream (AMSR) of a pre-denitritication-MBR was evaluated with the aim to achieve simultaneous sludge minimization and phosphorous removal. The excess sludge production was reduced by 64% when the AMSR was operated under 8 h of hydraulic retention time (HRT). The highest nutrients removal performances referred to organic carbon (98%), nitrogen (90%) and phosphorous (97%) were obtained under 8 h of HRT. In contrast, prolonged anaerobic-endogenous conditions were found to be detrimental for all nutrients removal performances. Similarly, the lowest membrane fouling tendency (FR = 0.65∙1011 m−1 d−1) was achieved under 8 h of HRT, where…

Pancreatic T cell protein-tyrosine phosphatase deficiency ameliorates cerulein-induced acute pancreatitis.

2014

Background Acute pancreatitis (AP) is a common clinical problem whose incidence has been progressively increasing in recent years. Onset of the disease is trigged by intra-acinar cell activation of digestive enzyme zymogens that induce autodigestion, release of pro-inflammatory cytokines and acinar cell injury. T-cell protein tyrosine phosphatase (TCPTP) is implicated in inflammatory signaling but its significance in AP remains unclear. Results In this study we assessed the role of pancreatic TCPTP in cerulein-induced AP. TCPTP expression was increased at the protein and messenger RNA levels in the early phase of AP in mice and rats. To directly determine whether TCPTP may have a causal rol…

2020

The diffusion of antibiotic resistance determinants in different environments, e.g., soil and water, has become a public concern for global health and food safety and many efforts are currently devoted to clarify this complex ecological and evolutionary issue. Horizontal gene transfer (HGT) has an important role in the spread of antibiotic resistance genes (ARGs). However, among the different HGT mechanisms, the capacity of environmental bacteria to acquire naked exogenous DNA by natural competence is still poorly investigated. This study aimed to characterize the ability of the environmental Escherichia coli strain ED1, isolated from the crustacean Daphnia sp., to acquire exogenous DNA by …

Overreporting Oil Reserves

2009

An increasing number of oil market experts argue that OPEC members substantially overstate their oil reserves. While the economic implications could be dire, the incentives for overreporting remain unclear. This paper analyzes these incentives, showing that oil exporting countries may overreport to raise expected future supply, discourage oil-substituting R&D, and hence improve their future market conditions. Overreporting, however, comes at a cost since it must be backed by observable actions and therefore induces costly distortions of supply. Surprisingly, these latter can eliminate other distortions that arise regardless of information asymmetries in presence of endogenous technological …

A Further Note on Endogenous Spillovers in a Non-tournament R&D Duopoly

2008

This note considers the paper of Poyago-Theotoky (1999) on strategic R&D with endogenous spillovers. It proves through an example that, under R&D collusion, optimality sometimes requires either minimal or asymmetric spillovers. It also provides a simple sufficient condition for optimal spillovers between colluding firms to involve maximal spillovers (i.e., complete sharing of information).

Single-tube nested quantitative PCR: a rational and sensitive technique for detection of retroviral DNA. Application to RERV-H/HRV-5 and confirmation…

2003

It was reported earlier that a few patients suffering from non-Hodgkin's lymphoma had low amounts of DNA from the so-called fifth human exogenous retrovirus, HRV-5. A sensitive and rational method for large-scale screening for HRV-5 DNA was therefore developed. It is a single-tube nested quantitative PCR (stnQPCR), which uses two functionally isolated primer pairs and one probe target distinct from related endogenous retroviral sequences, yet encompassing known HRV-5 variation, allowing optimal use of sequence conservation. DNA from lymphoma, myeloma, and follicular dendritic cell lines was tested for HRV-5 positivity, as was DNA from whole blood of blood donors, non-Hodgkin's lymphoma and …

Factors Governing the Chemical Stability and NMR Parameters of Uracil Tautomers and Its 5-Halogen Derivatives

2020

We report on the density functional theory (DFT) modelling of structural, energetic and NMR parameters of uracil and its derivatives (5-halogenouracil (5XU), X = F, Cl, Br and I) in vacuum and in water using the polarizable continuum model (PCM) and the solvent model density (SMD) approach. On the basis of the obtained results, we conclude that the intramolecular electrostatic interactions are the main factors governing the stability of the six tautomeric forms of uracil and 5XU. Two indices of aromaticity, the harmonic oscillator model of aromaticity (HOMA), satisfying the geometric criterion, and the nuclear independent chemical shift (NICS), were applied to evaluate the aromaticity of ur…

Missense variants in DPYSL5 cause a neurodevelopmental disorder with corpus callosum agenesis and cerebellar abnormalities

2021

International audience; The collapsin response mediator protein (CRMP) family proteins are intracellular mediators of neurotrophic factors regulating neurite structure/spine formation and are essential for dendrite patterning and directional axonal pathfinding during brain developmental processes. Among this family, CRMP5/DPYSL5 plays a significant role in neuronal migration, axonal guidance, dendrite outgrowth, and synapse formation by interacting with microtubules. Here, we report the identification of missense mutations in DPYSL5 in nine individuals with brain malformations, including corpus callosum agenesis and/or posterior fossa abnormalities, associated with variable degrees of intel…

Effect of Chlorhexidine on durability of two self-etch adhesive systems

2020

Background Despite of the rapid development in the field of dental adhesives, the issue of reduction in dentin bond durability has still not been resolved. The activity of dentinal endogenous enzymes such as MMPs is one of the most important causes of failure in resin composite restorations. The aim of this study was to investigate the influence of Chlorhexidine on micro-tensile bond strength of two types of commercially available self-etch adhesives. Material and Methods Twenty four sound and freshly extracted molars were selected. Four standardized flat mid-coronal dentinal disks were prepared from each tooth. The specimens were randomly assigned to 6 groups (n=16). Groups A(control group…