Search results for "GiST"
showing 10 items of 3463 documents
The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease
2020
© 2020 The Author(s).
Impact of non-selective ß-blockers on hepatic encephalopathy in patients with liver cirrhosis
2020
Non-selective β-blockers (NSBB) are frequently used for the treatment of portal hypertension and gastroesophageal varices in patients with liver cirrhosis; however prospective studies investigating the potential association between NSBB use and hepatic encephalopathy (HE) are still scarce. We investigated the potential association between NSBB use and the presence of covert HE (CHE) as well as the development of overt HE (OHE).224 patients with liver cirrhosis were included into this cohort study at two German centers and followed for a median of 364 days. CHE was diagnosed by pathological results in the PHES. Predictors for the presence of CHE or the development of OHE were analyzed using …
The association between education level and chronic liver disease of any etiology
2020
Abstract Background The potential link between educational level and chronic liver diseases (CLD) were explored using the mortality records of liver cirrhosis, which lack accuracy and are unable to identify the different etiological factors of liver cirrhosis. Information on the association of low educational level with the severity of CLD is lacking. Aim To evaluate the potential association linking education level to etiology and clinical stage of CLD cases. Methods Consecutive enrolment of 11,107 subjects with CLD aged≥18 years prospectively recruited in two national surveys in 2001 and 2014 at one of the participating Italian liver units throughout the country. Subjects were pooled in t…
Management of hepatic encephalopathy in Germany: a survey among physicians
2020
Hepatic encephalopathy (HE) is a severe complication of liver cirrhosis with impairment of quality of life and prognosis. Management patterns among physicians have not been investigated yet. A questionnaire containing 17 questions was sent out to 1468 gastroenterologists and 120 general practitioners (GPs). It included questions regarding diagnostic, therapeutic, and management strategies used in patients with overt HE (OHE) and covert HE (CHE). The response rate was 12 % (n = 172) for gastroenterologists and 45 % (n = 54) for GPs. Of gastroenterologists, 26.7 % examine patients with an initial diagnosis of liver cirrhosis regarding HE. Gastroenterologists favored a combination of differen…
β-Thalassemia heterozygote state detrimentally affects health expectation.
2018
Background: Thalassemia minor (Tm) individuals, are generally considered healthy. However, the prognosis of Tm individuals has not been extensively studied. The aim of this study was to evaluate the prognosis of Tm versus controls without β-thalassemia carrier state. Methods: A total of 26,006 individuals seeking thalassemia screening at the AOOR Villa Sofia-V. Cervello, Palermo (Italy) were retrospectively studied. Logistic penalised regression model was used to estimate risk of potential complications and survival techniques were used to study mortality. Results: We identified a total of 4943 Tm and 21,063 controls. Tm was associated with significantly higher risks of hospitalisation for …
Dynamics of liver stiffness by transient elastography in patients with chronic hepatitis C virus infection receiving direct-acting antiviral therapy-…
2020
The impact of direct-acting antiviral (DAA) therapies on fibrosis regression remains uncertain. In the current study, we prospectively evaluated dynamics of liver stiffness by transient elastography (TE) in patients with chronic HCV infection receiving DAA-based treatment. Patients (260) were enrolled in the German Hepatitis C-Registry (DHC-R), a national multicentre real-world cohort. Liver stiffness (LS) was assessed at baseline, end of treatment (EOT) and 24 weeks after EOT (FU24) by TE. Biochemical, virological and clinical data were obtained in parallel. In patients with SVR, there was a significant improvement of LS between baseline (median [range], 8.6 [1.7-73.5] kPa) and FU24 (7.9 […
Heraldiskās simbolikas attīstība Latvijas teritorijā, 13.-16.gs.
2018
Bakalaura darba „Heraldiskās simbolikas attīstība Latvijas teritorijā, 13.-16.gs.” uzdevums ir apkopot galveno heraldiskās simbolikas avotu grupu – sfragistisko un numismātisko avotu – piemērus, ar mērķi atspoguļot heraldiskās simbolikas attīstību Latvijas teritorijā no Rietumu kultūras ienākšanas brīža līdz Livonijas pastāvēšanas beigām. Darba struktūru veido četras nodaļas, kurās atspoguļota heraldikas attīstība, lietošanas principi. Pirmā nodaļa veltīta procesiem, kuru rezultātā reģionā ienāk heraldika, bet pārējās trīs nodaļas iedalītas atbilstoši avotu grupām – sfragistika, numismātika, un avoti, kas nav ierindojami šajās avotu grupās.
Heraldiskās simbolikas attīstība Livonijā, 13.-16.gs.
2020
Maģistra darba „Heraldiskās simbolikas attīstība Livonijā, 13.-16.gs.” mērķis ir apkopot un analizēt galveno heraldiskās simbolikas avotu grupu – sfragistisko un numismātisko avotu – piemērus, ar mērķi atspoguļot heraldiskās simbolikas attīstību Livonijā no Rietumu kultūras ienākšanas brīža līdz pat Livonijas pastāvēšanas beigām. Darba struktūru veido četras nodaļas, kurās atspoguļota heraldikas attīstība, lietošanas principi. Pirmā nodaļa veltīta heraldikas attīstībai un procesiem, kuru rezultātā Livonijā ienāk heraldika, bet pārējās trīs nodaļas iedalītas atbilstoši avotu grupām – sfragistika, numismātika, un citi avoti, kuros sastopami ģerboņu atveidojumi.
Innovation activity of SMEs in different locations
2013
Todtling and Trippl (2005) argue that innovation activity is a key element in regional economic development (see also Ronde and Hussler, 2005; Audretsch and Lehmann, 2005; Cooke, 2005). However, we know little about the formation, development and diffusion of innovations in different milieux. The aim of this study is to clarify the factors – in particular, the regional factors – that affect the innovation activity of small and medium-sized enterprises (SMEs). Our analyses of the innovation activity of Finnish SMEs revealed that innovation activity is very brisk in towns and relatively brisk in rural areas, although the difference between the two was not statistically significant. A logistic…
La nomina di Lodovico Mortara a primo presidente della Corte di Cassazione romana
2019
L’autore, prendendo spunto da un recente libro di Massimiliano Boni e da un articolo pubblicato sul Giornale d’Italia del 30 aprile 1915, ricostruisce la vicenda della tormentata “corsa” di Lodovico Mortara per la presidenza alla Cassazione romana. Ricostruisce anche taluni aspetti della personalità di Mor- tara e degli altri magistrati coinvolti, prendendo in esame le diverse ipotesi circa la possibile paternità dell’articolo sopra menzionato. The author, taking the cue from a recent book by Massimiliano Boni and from an article published in the Giornale d’Italia (April, 30th, 1915), recon- structs the story of the tormented “race” of Lodovico Mortara for the presi- dency of the Roman Cass…