Search results for "GiST"

Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and …

2016

WOS: 000393031600001

[Atrial fibrillation in patients with COVID-19. Usefulness of the CHA

2021

Resumen Introduccion y objetivos La enfermedad por coronavirus de 2019 (COVID-19) esta causada por el segundo coronavirus del sindrome respiratorio agudo y grave. La fibrilacion auricular (FA) es comun en situaciones agudas, en las que conlleva mas complicaciones y mortalidad. Metodos Analisis del Registro internacional HOPE (NCT04334291); el objetivo es evaluar la informacion pronostica de FA en pacientes con COVID-19. Se realizo un analisis multivariable y un emparejamiento por puntuacion de propension para evaluar la relacion entre FA y mortalidad. Ademas, se evaluo en estos pacientes el impacto en la mortalidad y los eventos embolicos de la puntuacion CHA2DS2-VASc. Resultados Entre los …

Emballage, logistique et économie circulaire : prémices d'un nouveau packaging scorecard

2017

International audience; – Dans les systèmes de production comme de commercialisation et de consommation actuels, l'emballage est omniprésent. Ses fonctions sont multiples. Elles concernent autant la qualité des produits qu'il contient, leur mise en valeur par ses aspects marketing, que la logistique via les activités de manutention, de stockage et de transport qu'il permet. Partenaire indispensable des différents acteurs (fournisseurs, industriels, prestataires de services logistiques, transporteurs, grossistes, détaillants, consommateurs) au sein des chaînes logistiques, il a donné lieu, depuis les années 2000, à l'élaboration de packaging scorecards. Cependant, face au changement de parad…

Knowledge of alpha-1 deficiency and primary ciliary dyskinesia by medical students and health professionals

2016

Background: Under-diagnosis and delayed diagnosis are common features in rare diseases, which have negative effects on the patients9 prognosis. A possible explanation could be lack of awareness and education of the health professionals involved in the managements of these patients. Alpha-1-antitrypsin deficiency (AATD) and primary ciliary dyskinesia (DCP) are under-diagnosed rare diseases showing a median diagnosis delay of five to ten years. Methods: A survey was undertaken in paediatricians (general, paediatric pulmonologists and paediatric gastroenterologist) and medical school students to assess their knowledge on AATD and PCD. Results: A total of 624 surveys on AATD and 457 on PCD were…

Paesaggi locali

2009

Common variants conferring risk of schizophrenia

2009

Schizophrenia is a complex disorder, caused by both genetic and environmental factors and their interactions. Research on pathogenesis has traditionally focused on neurotransmitter systems in the brain, particularly those involving dopamine. Schizophrenia has been considered a separate disease for over a century, but in the absence of clear biological markers, diagnosis has historically been based on signs and symptoms. A fundamental message emerging from genome-wide association studies of copy number variations (CNVs) associated with the disease is that its genetic basis does not necessarily conform to classical nosological disease boundaries. Certain CNVs confer not only high relative ris…

Determinants of elimination decisions in the activity scheduling process

2016

[EN] This paper presents an analysis on the determinants related to a particular rescheduling decision in the activity-travel scheduling process: elimination decisions, which consist in the non-execution of pre-planned activity-travel episodes. Data used come from an in-depth computer-assisted telephone interview (CATI) follow up survey carried out during the implementation of the first wave of an activity scheduling process panel survey. Open-ended answers related to the reasons associated to changes between pre-planned and executed agenda are studied. First, an interpretative qualitative method based on analytic induction (AI) is used to cope with the complex nature of the rescheduling de…

Effects of a Travel Behaviour Change Program on Sustainable Travel

2018

The main objective of the present study is to analyse the effect of a Travel Behaviour Change Program (TBCP) based on health improvement actions, in relation to a potential for an increase in walking and cycling, with reference to particular groups of people defined according to sociodemographics. A TBCP consisting of three persuasion actions based on health improvements was planned and executed in Valencia (Spain). A two-wave panel survey was used to study the effects of taking part in the TBCP. The panel survey collected data related to activity-travel scheduling process before and after the execution of the TBCP. To study the influence of participating in the TBCP, respondents were separ…

Cumbersome but desirable—Breaking the code of everyday cycling

2020

IntroductionCycling for transport could integrate physical activity (PA) into daily routines and potentially increase total PA levels. However, for parents with young children, most factors affecting transport mode choice tend to facilitate car use. Greater insight is necessary into reasons for (not) using sustainable transport modes in parents with young children. Therefore, the objective of this study was to explore the experiences, including motives, perceptions, attitudes, and norms, of parents of young children by using an e-bike, a longtail bike, and a traditional bike for everyday travel to the workplace, kindergarten, and the grocery store during the autumn, winter, and spring, in n…

Recommendations for neonatologists and pediatricians working in first level birthing centers on the first communication of genetic disease and malfor…

2021

Abstract Background Genetic diseases are chronic conditions with relevant impact on the lives of patients and their families. In USA and Europe it is estimated a prevalence of 60 million affected subjects, 75% of whom are in developmental age. A significant number of newborns are admitted in the Neonatal Intensive Care Units (NICU) for reasons different from prematurity, although the prevalence of those with genetic diseases is unknown. It is, then, common for the neonatologist to start a diagnostic process on suspicion of a genetic disease or malformation syndrome, or to make and communicate these diagnoses. Many surveys showed that the degree of parental satisfaction with the methods of c…