Search results for "GiST"

showing 10 items of 3463 documents

Pharmacokinetics of Direct Oral Anticoagulants in Emergency Situations: Results of the Prospective Observational RADOA-Registry

2021

Thrombosis and haemostasis 122(4), 552-559 (2022). doi:10.1055/a-1549-6556

medicine.medical_specialtymedicine.drug_classPyridonesAdministration OralHemorrhagePharmacokineticsRivaroxabanInternal medicineAtrial FibrillationmedicineHumansProspective StudiesRegistriesRivaroxabanbusiness.industryAnticoagulantAnticoagulantsHematologyEmergency situationsConfidence intervalDabigatranClinical trialApixabanObservational studybusinessmedicine.drug
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Antithrombotic treatment and outcomes of splanchnic vein thrombosis in an international prospective registry: Results of 2-year follow-up

2014

Abstract Background: Little information is available on the long-term clinical outcome of patients with splanchnic vein thrombosis (SVT). We aimed to assess incidence rates of bleeding, recurrence, and mortality in a large prospective cohort of SVT patients after a 2-year follow-up. Methods: Consecutive SVT patients were enrolled in a multicenter international registry, from 2008 to 2012. Information was gathered on baseline characteristics, risk factors and therapeutic strategies. Clinical outcomes (major bleeding; vascular events, defined as venous or arterial thrombosis, and mortality) during follow-up were collected and reviewed by a Central Adjudication Committee. Major bleeding was de…

medicine.medical_specialtymedicine.drug_classliver cirrhosisImmunologyanticoagulant agentBiochemistrymaleInternal medicinedeathMedicinefollow upartery thrombosishumanRisk factorProspective cohort studythrombosisriskregisteranticoagulant therapybusiness.industryhematologyIncidence (epidemiology)pathogenesisAnticoagulantCell Biologymedicine.diseasebleedingThrombosismortalitySurgeryVenous thrombosissocietySplanchnic vein thrombosisvein thrombosisrisk factorsolidincidenceantivitamin KpatientbusinessAmericanFibrinolytic agentneoplasmhospitalizationportal vein
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Frequency and determinants for hemorrhagic transformation of posterior cerebral stroke : Posterior ischemic stroke and hemorrhagic transformation.

2017

BACKGROUND: hemorrhagic transformation is a threatening ischemic stroke complication. Frequency of hemorrhagic transformation differs greatly among studies, and its risk factors have been usually studied in patients with anterior ischemic stroke who received thrombolytic therapy. We evaluated, in a hospital-based series of patients with posterior ischemic stroke not treated with thrombolysis, frequency and risk factors of hemorrhagic transformation. Patients with posterior circulation stroke were seen in our Department during the period January 2004 to December 2009. Demographic and clinical information were collected. We estimated risk for spontaneous hemorrhagic transformation by means of…

medicine.medical_specialtymedicine.medical_treatmentCerebral strokeLogistic regressionGeneral Biochemistry Genetics and Molecular BiologyBrain ischemia03 medical and health sciences0302 clinical medicineInternal medicineEpidemiologymedicinebiochemistry030212 general & internal medicineStrokebusiness.industryposterior ischemic strokegenetics and molecular biology (all)epidemiology; hemorrhagic transformation; posterior ischemic stroke; biochemistry genetics and molecular biology (all)General MedicineThrombolysismedicine.diseaseSurgeryhemorrhagic transformationIschemic strokeCardiologyepidemiologyComplicationbusiness030217 neurology & neurosurgery
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Prevalence of xerostomia in patients attending Shorish dental speciality in Sulaimani city

2014

Objectives: The aim of this study was to investigate the prevalence of xerostomia among dental patients and explo - re the possible risk factors and symptoms associated with this condition. Study Design: The prevalence of xerostomia and its associations were investigated among patients (n=1132) who were visiting the department of oral medicine at shorish dental speciality in sulaimani city. The age range was bet - ween 10-79 years. 512 (45.2%) of participants were males and 620 (54.8%) were females. The data collected were age, sex, systemic diseases, medications and habit of smoking. Logistic regression models to estimate odds ratios and 95% confidence intervals were used to investigate th…

medicine.medical_specialtymedicine.medical_treatmentDentistryOdontologíaLogistic regressionstomatognathic systemInternal medicineDiabetes mellitusChi-square testotorhinolaryngologic diseasesMedicineIn patientGeneral DentistryOral Medicine and Pathologybusiness.industryResearchOdds ratiomedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludConfidence intervalstomatognathic diseasesUNESCO::CIENCIAS MÉDICASAntihistaminebusinessOral medicine
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Associated Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Registry: What Have We Learned?

2020

In 2007, the first associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure was performed in Regensburg, Germany. ALPPS is a variation of two-stage hepatectomy to induce rapid liver hypertrophy allowing the removal of large tumors otherwise considered irresectable due to a too small future liver remnant. In 2012, the international ALPPS registry was created, and it now contains more than 1,000 cases. During the past years, improved patient selection and refinements in operative techniques, in particular, less invasive approaches such as Partial ALPPS, Tourniquet ALPPS, Ablation-assisted ALPPS, Hybrid ALPPS or Laparoscopic or Robotic approaches, have resu…

medicine.medical_specialtymedicine.medical_treatmentLess invasivePortal vein ligationReviewResection03 medical and health sciences0302 clinical medicineCarcinomaHepatectomyHumansMedicineRegistriesPerihilar CholangiocarcinomaRandomized Controlled Trials as TopicTwo-stage hepatectomyALPPS registryHepatologyPortal Veinbusiness.industryCarcinoma hepatocellularLiver NeoplasmsGastroenterologymedicine.diseaseSurgeryTreatment OutcomeBile Duct NeoplasmsLiver030220 oncology & carcinogenesisHepatocellular carcinoma030211 gastroenterology & hepatologyALPPSOutcome dataHepatectomyPerihilar cholangiocarcinomabusinessGut and Liver
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No difference in 30-day outcome and quality of life in transradial versus transfemoral access – results from the German Austrian ABSORB registry (GAB…

2021

Abstract Background Radial (RA) instead of femoral access (FA) for coronary interventions has become a European Society of Cardiology Class-IA guideline recommendation. But when the decision on the access site is left to the discretion of the operator, differences in adverse event rates mitigate. Methods We compared the 30-day outcome for RA and FA in all patients recruited for the observational German Austrian ABSORB Registry (GABI-R) in regard to all-cause mortality, stroke, myocardial infarction (MI), TIMI major bleedings (TMB) and quality of life (QoL). All patients were treated with a bioresorbable vascular scaffold. Access site was left to the discretion of the operator. Results In to…

medicine.medical_specialtymedicine.medical_treatmentMyocardial InfarctionHemorrhagePercutaneous Coronary InterventionQuality of lifemedicineHumansMyocardial infarctionRegistriesStrokebusiness.industryPercutaneous coronary interventionGeneral MedicineGuidelinemedicine.diseaseFemoral ArteryStrokeTreatment OutcomeAustriaEmergency medicineCohortConventional PCIRadial ArteryQuality of LifeCardiology and Cardiovascular MedicinebusinessTIMI
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Prevalence of Vertebral Fractures and Their Prognostic Significance in the Survival in Patients with Chronic Kidney Disease Stages 3‒5 Not on Dialysis

2020

Background: The prevalence of vertebral fractures (VF) and their association with clinical risk factors and outcomes are poorly documented in chronic kidney disease (CKD) cohorts. The aim of the study was to evaluate the prevalence of VF in patients with non-dialysis dependent CKD (NDD-CKD), their value in predicting mortality and its correlation with parameters of bone mineral metabolism and vascular calcification. Materials and Methods: 612 NDD 3‒5 stage CKD patients participating in the OSERCE-2 study, a prospective, multicenter, cohort study, were prospectively evaluated and categorized into two groups according to presence or absence of VF at enrollment. VF were assessed with lateral r…

medicine.medical_specialtymedicine.medical_treatmentOsteoporosis030232 urology & nephrologylcsh:Medicine030209 endocrinology & metabolismLogistic regressionArticle03 medical and health sciences0302 clinical medicineInternal medicinemedicineRisk factorSurvival analysisDialysisVascular diseasebusiness.industrylcsh:RGeneral Medicinefracturesmedicine.diseasevascular calcificationbusinesschronic kidney diseaseCohort studyKidney diseaseJournal of Clinical Medicine
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Predictive Score of Nodal Involvement in Endometrial Cancer Patients: A Large Multicentre Series

2021

Background: Sentinel lymph node (SLN) biopsy is considered the standard of care in early-stage endometrial cancer (EC). For SLN failure, a side-specific lymphadenectomy is recommended. Nevertheless, most hemipelvises show no nodal involvement. The authors previously published a predictive score of lymphovascular involvement in EC. In case of a negative score (value 3–4), the risk of nodal metastases was extremely low. This multicenter study aimed to analyze a predictive score of nodal involvement in EC patients. Methods: The study enrolled patients with EC who had received comprehensive surgical staging with nodal assessment. A preoperative predictive score of nodal involvement was calculat…

medicine.medical_specialtymedicine.medical_treatmentSentinel lymph nodeLogistic regressionBiopsyHumansMedicineEndometrial NeoplasmNeoplasm Stagingmedicine.diagnostic_testbusiness.industrySentinel Lymph Node BiopsyEndometrial cancerArea under the curveLymph NodeLymphatic MetastasiOdds ratiomedicine.diseaseConfidence intervalEndometrial NeoplasmsOncologyLymphatic MetastasisLymph Node ExcisionSurgeryLymphadenectomyFemaleLymph NodesRadiologySentinel Lymph NodebusinessHuman
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Multimorbidity and anxiety symptoms among adults aged 50 years and over from six low- and middle-income countries

2021

Currently, there are limited data on the association between multimorbidity (i.e., ≥ 2 chronic conditions) and anxiety, especially among the older population in low- and middle-income countries (LMICs). Thus, the aim of the present study was to examine the association between multimorbidity and anxiety symptoms in a large sample of adults aged ≥ 50 years from six LMICs (China, India, Ghana, Mexico, Russia, South Africa). Cross-sectional, nationally representative, community-based data from the Study on Global Ageing and Adult Health (SAGE) were analysed. A total of 11 chronic physical conditions were assessed. Anxiety symptoms referred to extreme/severe problems with worry or anxiety in the…

medicine.medical_specialtymultimorbiditybusiness.industrymedia_common.quotation_subjectmulticountryLogistic regressionanxietyOddsOlder populationLow and middle income countriesEpidemiologymedicineAnxietySmıth L. F. López Sánchez G. Shin J. I. Soysal P. Veronese N. -Multimorbidity and Anxiety Symptoms among Adults Aged 50 Years and Over from Six Low- and Middle-Income Countries- Journal of Ageing and Longevity cilt.1 sa.1 ss.36-47 2021epidemiologylow- and middle-income countriesmedicine.symptomWorrybusinessAdult healtholder adultsDemographymedia_common
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Impact of a physician-targeted letter on opioid prescribing.

2020

We study the effect of a physician-targeted nudge letter on opioid prescribing. In May 2017, the Social Insurance Institution of Finland sent a personal information letter to all physicians who had issued a prescription containing at least 100 tablets of paracetamol-codeine combination to a new patient. The aim of the letter was to draw the physicians’ attention to their prescribing practices and to decrease the size of the first codeine prescription. Using individual level register data and a difference-in-differences strategy, we estimate that the letter decreased the average number of tablets purchased by new patients by 12.5 percent and the probability of a first purchase being at least…

medicine.medical_specialtyprescription drugslääkemääräyksetOpioid prescribingSocial insuranceinformation letter03 medical and health sciencesopioiditdifference-in-differencesPhysicians0502 economics and businessmedicinelääketurvallisuusHumans050207 economicsMedical prescriptionlääkäritPractice Patterns Physicians'Finlandohjeetbusiness.industry030503 health policy & servicesHealth Policy05 social sciencesCodeineKansaneläkelaitospalautePublic Health Environmental and Occupational HealthIndividual levelKELADifference in differencesreseptilääkkeetAnalgesics OpioidlääkkeetRegister dataFamily medicineopioid prescribing0305 other medical sciencebusinessPersonally identifiable informationmedicine.drugJournal of health economics
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