Search results for "Gili"
showing 10 items of 234 documents
HOLONIC PRODUCTION SYSTEM TO OBTAIN FLEXIBILITY FOR CUSTOMER SATISFACTION
2008
The Holonic Production System (HPS) can be a valid choice to overcome the problems of traditional production sys-tems’ architectures, thanks to its capability to adapt and react to changes in the business environment whilst being able to maintain systemic synergies and coordination. The HPS is made of holons seen as functional production units which are simultaneously autonomous and cooperative. Although the holonic approach could represent a valid solution in order to pursue the necessary levels of agility of production systems, they have been scarcely implemented in practice and even less studied from a business studies perspective. The purpose of this discussion paper is to show the bene…
Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice.
2018
Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190540 También participan en la elaboración de este artículo científico: Aracely Calatayud-Pascual, Alicia López-Castellano, Elena P. Albelda, Enrique García-España, Luis Martí-Bonmatí, Juan C. Frias y M. Teresa Albelda. Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment.
Identificación de biomarcadores de fragilidad en estudio de Toledo de envejecimiento saludable
2014
Debido al aumento de la esperanza de vida y a la disminución de la tasa de fecundidad producido en las últimas décadas, la proporción de personas mayores de 60 años está aumentando más rápidamente que cualquier otro grupo de edad. Este envejecimiento de la población ha suscitado un gran interés en el estudio del envejecimiento y en cómo hacer frente a los problemas relacionados con él. Tradicionalmente, la mayor parte de la investigación en este ámbito se ha centrado en la supervivencia y en las posibles intervenciones para prolongar la esperanza de vida. Sin embargo, la tendencia actual es a considerar más importante la prevención de la discapacidad (healthspan) que el simple aumento de la…
Orthilia secunda (L.) House, nueva especie para la flora cantábrica
2014
P. 99-102 Hemos encontrado en un hayedo submesófilo basófilo orocantábrico una población de la especie Orthilia secunda (L.) House, novedad para la Cordillera Cantábrica y la mitad oeste peninsular. Se estudia la composición florística del sotobosque y se enfatiza la fragilidad de la comunidad derivada de las complejas relaciones tróficas micorríticas de las especies inventariadas. Se propone su inclusión en el Catálogo de Flora Protegida de Castilla y León. SI
Fragilità e situazioni carcerarie tra circuiti, sezioni protette e diritti negati
2023
Uno sguardo alle funzioni del carcere attraverso la lente della fragilità consente di mettere in luce i limiti dell’attuale sistema penitenziario invitando l’interprete a riflettere su possibili soluzioni per contenerne i noti effetti negativi. L’organizzazione degli spazi, tra circuiti, sezioni e regimi, è espressione di come negli anni sia prevalsa la preoccupazione per la sicurezza, finendo, questa, per assorbire la rieducazione e la tutela di tanti diritti dei detenuti. A look at the functions of the prison through the lens of fragility allows us to highlight the limits of the current penitentiary system, inviting the interpreter to reflect on possible solutions to contain its known neg…
Masonry structures: A proposal of analytical generation of fragility functions for tsunami impact – Application to the Mediterranean coasts
2021
Abstract Evaluation of tsunami vulnerability of coastal buildings is gaining high interest in recent years in the areas with high tsunami hazard. Fragility evaluation is a fundamental step to obtain a quantitative estimation of the probability of building damage and in order to define possible strategies for risk mitigation. Several empirical fragility curves are available for masonry structures. However, an empirical fragility curve is generally based on field surveys after tsunami events, not always available. Conversely, analytical fragility curves are based on prediction approaches. In this paper, a proposal for the evaluation of analytical fragility curves for masonry structures typica…
MAPS. European program case-study. Military assets as public spaces
2019
The call concerns the project experience developed by the research group of Politecnico di Milano - Piacenza Campus – leaded and coordinated by Guya Bertelli (1), as part of the European program MAPS (Military Assets as Public Spaces), supported by URBACT (2), oriented to the development of urban policies. This participation gave the opportunity to the components of the research unit to experiment processes of sharing and examination on the meaning of public space in the contemporary city, mainly in disused and fragile contexts. The project network is composed by 9 cities of as many European countries, with the Municipality of Piacenza as leader: Serres (Greece), Varazdin (Croatia), Szombat…
Crisis, pandemia y fragilidades : reflexiones desde un ?balcón sociológico?.
2020
La crisis derivada de la pandemia por COVID-19 en la que se encuentran nuestras sociedades, nos lleva a pensar en la fragilidad o la incertidumbre como piezas fundamentales de ellas, y a reflexionar sobre las consecuencias sociales de esta situación. La relación cotidiana con una situación de confinamiento a la que nunca antes nos habíamos enfrentado, ha hecho resquebrajarse nuestra forma de gestionar el tiempo, de relacionarnos, de trabajar, de estudiar… Todo ello conllevará un nuevo escenario social en el que se sucederán multitud de preguntas a las que la Sociología deberá dar respuesta al tiempo que soluciones para las consecuencias sociales de esta crisis.
La derechización del mundo
2007
Family studies in scleroderma (systemic sclerosis) demonstrating an HLA-linked increased chromosomal breakage rate in cultured lymphocytes
1988
An increased chromosomal breakage rate (ICBR) was found in 27 of 28 patients with scleroderma (systemic sclerosis, SS) - 5 with the syndrome including calcinosis cutis, Raynaud phenomenon, esophagus hypomotility, sclerodactyly and telangiectasia (CREST), 4 incomplete CREST, 1 overlapping syndrome, 18 progressive systemic sclerosis (PSS). Not only the patients, but also about half of their first-degree relatives showed an increased chromosomal breakage rate (more than 5 breaks per 100 metaphases). This character segregated as a dominant marker in nine families of scleroderma patients. In the six informative of the nine families, the ICBR trait showed close linkage with the HLA region on chro…