Search results for "Ginecologia"

showing 10 items of 340 documents

A laparoscopic risk-adjusted model to predict major complications after primary debulking surgery in ovarian cancer: A single-institution assessment

2016

Abstract Objective To develop and validate a simple adjusted laparoscopic score to predict major postoperative complications after primary debulking surgery (PDS) in advanced epithelial ovarian cancer (AEOC). Methods From January 2006 to June 2015, preoperative, intraoperative, and post-operative outcome data from patients undergoing staging laparoscopy (S-LPS) before receiving PDS (n=555) were prospectively collected in an electronic database and retrospectively analyzed. Major complications were defined as levels 3 to 5 of MSKCC classification. On the basis of a multivariate regression model, the score was developed using a random two-thirds of the population (n=370) and was validated on …

Adultmedicine.medical_specialtyPost-operative complicationsPopulationLaparoscopy; Ovarian cancer; Post-operative complications; Predictive model; Obstetrics and Gynecology; OncologyRisk AssessmentYoung Adult03 medical and health sciencesGynecologic Surgical ProceduresPostoperative Complications0302 clinical medicineOvarian cancerAscitesHumansMedicineMajor complicationLaparoscopy; Ovarian cancer; Post-operative complications; Predictive modelYoung adultLaparoscopyeducationAgedAged 80 and overOvarian Neoplasmseducation.field_of_studyModels Statistical030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryReproducibility of ResultsObstetrics and GynecologyMiddle Agedmedicine.diseaseDebulkingSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAItalyOncologyPredictive model030220 oncology & carcinogenesisFemaleLaparoscopymedicine.symptombusinessOvarian cancerRisk assessment
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Is intravesical instillation of hyaluronic acid and chondroitin sulfate useful in preventing recurrent bacterial cystitis? A multicenter case control…

2015

Abstract Objective Urinary tract infections (UTIs) are common in the female population and, over a lifetime, about half of women have at least one episode of UTI requiring antibiotic therapy. The aim of the current study was to compare two different strategies for preventing recurrent bacterial cystitis: intravesical instillation of hyaluronic acid (HA) plus chondroitin sulfate (CS), and antibiotic prophylaxis with sulfamethoxazole plus trimethoprim. Materials and methods This was a retrospective review of two different cohorts of women affected by recurrent bacterial cystitis. Cases (experimental group) were women who received intravesical instillations of a sterile solution of high concen…

Adultmedicine.medical_specialtyRecurrent bacterial cystitismedicine.drug_classUrinary systemCystitiAntibioticsUrinalysislcsh:Gynecology and obstetricsGastroenterologyantibioticsantibiotics; chondroitin sulfate; cystitis; hyaluronic acidchemistry.chemical_compoundAdjuvants ImmunologicRecurrenceInternal medicineObstetrics and GynaecologyHyaluronic acidCystitismedicineHumansChondroitin sulfateAntibiotic prophylaxisHyaluronic Acidlcsh:RG1-991antibiotics chondroitin sulfate cystitis hyaluronic acidchondroitin sulfateRetrospective StudiesDose-Response Relationship Drugbusiness.industrySulfamethoxazoleChondroitin SulfatesAntibioticObstetrics and GynecologySettore MED/40 - Ginecologia E OstetriciaTrimethoprimSurgeryAdministration IntravesicalInstillation DrugchemistryUrinary Tract InfectionsDrug Therapy CombinationFemalebusinessmedicine.drugFollow-Up StudiesTaiwanese journal of obstetricsgynecology
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Role of one-step nucleic acid amplification (OSNA) to detect sentinel lymph node low-volume metastasis in early-stage cervical cancer.

2019

IntroductionGrowing evidence in the literature supports the accuracy of sentinel lymph node (SLN) biopsy in early-stage cervical cancer. One-step nucleic acid amplification (OSNA) is a rapid assay able to detect cytokeratin 19-mRNA in SLNs, and it can be used for intra-operative detection of low-volume metastases. The aim of this study was to evaluate the rate of low-volume metastasis in SLNs detected by OSNA in patients with early-stage cervical cancer. Secondary aims were to define the sensitivity and the negative predictive value of SLN biopsy assessed with OSNA.MethodsAfter IRB approval, consecutive patients who underwent surgery for International Federation of Gynecology and Obstetrics…

Adultmedicine.medical_specialtySentinel lymph nodeUterine Cervical NeoplasmsPilot ProjectsMetastasisCohort Studies03 medical and health sciencesCytokeratinsurgical oncology0302 clinical medicineSurgical oncologyPredictive Value of TestsBiopsymedicineHumansRNA MessengerStage (cooking)030304 developmental biologyNeoplasm StagingCervical cancerKeratin-190303 health sciencesmedicine.diagnostic_testbusiness.industrySentinel Lymph Node BiopsyObstetrics and GynecologyMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaLow volumeOncologylymphatic metastasi030220 oncology & carcinogenesisLymphatic MetastasisCervical cancerLymph Node Excisionneoplasm micrometastasiFemaleRadiologyLymph NodesSentinel Lymph NodebusinessNucleic Acid Amplification TechniquesInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society
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Differences in dyslipidemia between American and Italian women with polycystic ovary syndrome.

2008

Abstract BACKGROUND: Dyslipidemia is a common metabolic complication in polycystic ovary syndrome (PCOS). The aim of this study was to determine if differences exist in dyslipidemia in women with PCOS from different ethnic and geographical backgrounds. METHODS: This retrospective study evaluated the serum fasting lipid profiles of 106 women with PCOS from the United States and 108 women with PCOS from Italy evaluated at endocrinology clinics. RESULTS: American women had higher mean body mass index than Italian women (36.1+/-8.6 vs 28.1+/-5.8 kg/m2, p<0.01). Low HDL-cholesterol was the most prevalent lipid abnormality in both populations. U.S. women had higher mean levels of serum total chol…

Adultmedicine.medical_specialtySettore MED/09 - Medicina InternaEndocrinology Diabetes and MetabolismEthnic groupPhysiologySettore MED/13 - EndocrinologiaBody Mass IndexCohort StudiesEndocrinologyRisk FactorsmedicinePrevalenceHumansObesityPCOS Hyperandrogenism Cardiovascular risk dyslipidemia LDL-cholesterolDyslipidemiasRetrospective StudiesGynecologybusiness.industryRetrospective cohort studyOverweightmedicine.diseaseObesityPolycystic ovarySettore MED/40 - Ginecologia E OstetriciaLipidsConfidence intervalUnited StatesItalyCardiovascular DiseasesFemalebusinessBody mass indexDyslipidemiaCohort studyPolycystic Ovary SyndromeJournal of endocrinological investigation
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Self-Reported Long-Term Autonomic Function After Laparoscopic Total Mesometrial Resection for Early-Stage Cervical Cancer: A Multicentric Study.

2017

ObjectivesThis multicentric retrospective study investigates the early and long-term self-reported urinary, bowel, and sexual dysfunctions in early-stage cervical cancer patients who submitted to laparoscopic total mesometrial resection (L-TMMR), total laparoscopic radical hysterectomy, vaginal-assisted laparoscopic radical hysterectomy, and laparoscopic-assisted radical vaginal hysterectomy.MethodsCervical cancer patients, FIGO (International Federation of Gynecology and Obstetrics) stage IA2–IB1/IIA1 who submitted to nerve-sparing radical hysterectomy were recruited. Pelvic functions were assessed within 30 days (early outcome) and 12 months after surgery (long-term outcome).ResultsTwo hu…

Adultmedicine.medical_specialtyStress incontinenceConstipationSexual Dysfunctionmedia_common.quotation_subjectUrinary systemPhysiologicalUrinationUterine Cervical NeoplasmsAutonomic Nervous SystemHysterectomyUrination03 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansMesenteryRadical Hysterectomymedia_commonAgedNeoplasm StagingRetrospective StudiesCervical cancerAdult; Aged; Autonomic Nervous System; Female; Humans; Hysterectomy; Intestinal Diseases; Laparoscopy; Mesentery; Middle Aged; Neoplasm Staging; Retrospective Studies; Self Report; Sexual Dysfunction Physiological; Urination; Uterine Cervical Neoplasms; Young Adult; Oncology; Obstetrics and Gynecology030219 obstetrics & reproductive medicinebusiness.industryObstetrics and GynecologyRetrospective cohort studyPerioperativeMiddle Agedmedicine.diseaseSurgerycervical cancer total mesomeria resection early stageIntestinal DiseasesSexual Dysfunction PhysiologicalSettore MED/40 - GINECOLOGIA E OSTETRICIAOncology030220 oncology & carcinogenesisFemaleLaparoscopySelf Reportmedicine.symptombusinessInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society
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Minimally Invasive Pelvic Exenteration for Gynecologic Malignancies: A Multi-Institutional Case Series and Review of the Literature.

2019

ABSTRACT Study Objective To assess the feasibility and efficacy of minimally invasive pelvic exenteration (MIPE) in a multi-institutional Italian case series of women with gynecologic cancer and a review of the literature. Design Retrospective cohort study (Canadian Task Force classification II-2). Setting Three Italian university/teaching hospitals: “Agostino Gemelli” Foundation University Hospital in Rome, "ARNAS Civico Di Cristina Benfratelli” Hospital in Palermo, and “Maggiore della Carita” Hospital in Novara. Patients We reviewed all consecutive cases with gynecologic malignancies in this multi-institutional setting recorded between March 2014 and June 2017. Women with primary or centr…

Adultmedicine.medical_specialtySurvivalGenital Neoplasms FemaleSurgical complicationsmedicine.medical_treatmentTumor resectionLaparoscopic pelvic exenteration; Minimally invasive pelvic exenteration; Robotic pelvic exenteration; Surgical complications; Survival03 medical and health sciences0302 clinical medicineSurgical complicationmedicineRecurrent diseaseLaparoscopic pelvic exenterationHumansMinimally Invasive Surgical ProceduresLaparoscopyAgedRetrospective Studies030219 obstetrics & reproductive medicinePelvic exenterationmedicine.diagnostic_testbusiness.industryGeneral surgeryRobotic pelvic exenterationObstetrics and GynecologyRetrospective cohort studyPerioperativeCytoreduction Surgical ProceduresMiddle AgedPelvic ExenterationLaparoscopic pelvic exenteration Minimally invasive pelvic exenteration Robotic pelvic exenteration Surgical complications Survival Obstetrics and GynecologySettore MED/40 - GINECOLOGIA E OSTETRICIAMinimally invasive pelvic exenteration030220 oncology & carcinogenesisOperative timeFemaleElectronic databasebusinessJournal of minimally invasive gynecology
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Invasive cervical cancer during pregnancy: laparoscopic nodal evaluation before oncologic treatment delay

2010

Introduction. Cervical cancer is the most frequently encountered malignancy during pregnancy. Presence of nodal metastasis is the most important negative prognostic factor and its assessment represents a crucial parameter to decide if pregnancy can safely continue. We describe the results of 18 pregnant patients with cervical cancer who had their nodal status proved by means of laparoscopy. Material and methods. Eighteen patients with cervical cancer who underwent laparoscopic pelvic lymphadenectomy during pregnancy at Charit-University Berlin and Friedrich-Schiller-University Jena between 1999 and 2010 were analyzed retrospectively. Results. The mean age at diagnosis was 32 years (26-40) a…

Adultmedicine.medical_specialtyTime Factorsmedicine.medical_treatmentUterine Cervical NeoplasmsMalignancyMetastasisPregnancyLaparotomymedicineHumansCaesarean sectionNeoplasm StagingRetrospective StudiesCervical cancerPregnancyLaparoscopic lymphadenectomybusiness.industryGestational ageObstetrics and Gynecologymedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaSquamous carcinomaSurgeryOncologyLymphatic MetastasisCervical cancerLymph Node ExcisionPregancyFemaleLaparoscopyLymph NodesCervical cancer; Laparoscopic lymphadenectomy; PregancybusinessPregnancy Complications Neoplastic
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Radical vaginal trachelectomy (RVT) combined with laparoscopic lymphadenectomy: Prospective study of 225 patients with early-stage cervical cancer

2011

Objective: The aim of the study was to prove the surgical and oncological safety of radical vaginal trachelectomy (RVT) and laparoscopic lymphadenectomy for patients with early-stage cervical cancer who are seeking parenthood. Methods: A database of 225 patients with early-stage cervical cancer and intention to treat by RVT after laparoscopic lymphadenectomy was prospectively maintained. A total of 212 patients were treated according to the protocol. The procedure was preformed in a standardized manner, and life table analysis was applied. Results: In the cohort of patients treated according to protocol, 8 recurrences occurred and 4 patients died from recurrence. The median follow-up time w…

Adultmedicine.medical_specialtyUterine Cervical NeoplasmUrologyUterine Cervical NeoplasmsRadical vaginal trachelectomyAdenocarcinomaYoung AdultGynecologic Surgical ProceduresGynecologic Surgical ProcedureVaginal TrachelectomyEarly-stage cervical cancer; Fertility-preserving surgery; Radical vaginal trachelectomyMedicineHumansProspective StudiesStage (cooking)Prospective cohort studyLaparoscopic lymphadenectomyCervical cancerLaparoscopic lymphadenectomyIntention-to-treat analysisbusiness.industryMedicine (all)Fertility-preserving surgeryObstetrics and GynecologyPerioperativeMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaSurgeryProspective StudieOncologyEarly-stage cervical cancerCohortVaginaCarcinoma Squamous CellLymph Node ExcisionFemaleLaparoscopybusinessHuman
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Laparoscopic radical hysterectomy in cervical cancer as total mesometrial resection (L-TMMR): A multicentric experience

2015

Abstract Objective To analyze the feasibility of total mesometrial resection by laparoscopy (L-TMMR) in a multicentric series of early stage cervical cancer. Method We prospectively evaluated a consecutive series of cervical cancer patients with pre-operative FIGO stages IA2–IB1 at the Catholic University in Rome and in Campobasso and the Charite University in Berlin. All cases were assessed at pre-operative MRI scan and clinically confirmed by investigation under anesthesia, adhering strictly to the FIGO criteria. The surgical and post-surgical data were collected. Results 104 women with cervical cancer were admitted between July 2013 and August 2014 and among them 71 patients with pre-ope…

Adultmedicine.medical_specialtyUterine Cervical Neoplasmmedicine.medical_treatmentFistulaUterine Cervical NeoplasmsCervical CancerHysterectomyObstetrics and gynaecologymedicineHumansHemoperitoneumProspective StudiesStage (cooking)Prospective cohort studyLaparoscopyTotal Mesometrial Resection (TMMR)AgedNeoplasm StagingCervical cancerHysterectomymedicine.diagnostic_testbusiness.industryMedicine (all)Obstetrics and GynecologyMiddle Agedmedicine.diseaseSurgeryProspective StudieSettore MED/40 - GINECOLOGIA E OSTETRICIAOncologyLymph Node ExcisionLaparoscopyFemalelaparososcopicmedicine.symptombusinessHuman
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Ulipristal acetate versus leuprolide acetate for uterine fibroids

2012

A b s t r ac t Background The efficacy and side-effect profile of ulipristal acetate as compared with those of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are unclear. Methods In this double-blind noninferiority trial, we randomly assigned 307 patients with symptomatic fibroids and excessive uterine bleeding to receive 3 months of daily therapy with oral ulipristal acetate (at a dose of either 5 mg or 10 mg) or once-monthly intramuscular injections of leuprolide acetate (at a dose of 3.75 mg). The primary outcome was the proportion of patients with controlled bleeding at week 13, with a prespecified noninferiority margin of −20%. Results Uterine bleed…

Adultmedicine.medical_specialtyUterine fibroidsIntention to Treat AnalysiUrologyAdministration OralEndometriumInjections Intramuscularlaw.inventionchemistry.chemical_compoundYoung AdultEndometriumPrimary outcomeRandomized controlled trialDouble-Blind MethodlawUlipristal acetateSelective progesterone receptor modulatormedicineUterine NeoplasmUlipristalMenorrhagiaGynecologyIntention-to-treat analysisLeiomyomabusiness.industryObstetrics and GynecologyUterine bleedingUterine fibroids uterine leiomyomas uterine bleeding ulipristal acetate leuprolide acetate medical therapyGeneral MedicineNorpregnadieneMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E Ostetriciamedicine.anatomical_structurechemistryAmenorrheaFemalemedicine.symptomLeuprolidebusinessHuman
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