Search results for "Glaucoma"

showing 10 items of 317 documents

Spontaneous Resolution of Delayed Suprachoroidal Hemorrhage in the Single Eye Following Needling in Congenital Glaucoma

2017

Suprachoroidal hemorrhage (SCH) is a rare, but potentially vision-threatening event with poor long-term visual prognosis. At present, there is disagreement whether surgical intervention or conservative treatment is superior in the management. We report on a case of spontaneous resolution of severe SCH after needling procedure in the only eye of a young patient with congenital glaucoma.A 43-year-old woman with congenital glaucoma was scheduled for bleb needling in her only eye. Preoperative best-corrected visual acuity was 20/40 and intraocular pressure 20 mm Hg. On the third postoperative day, she developed a massive delayed SCH with appositional (kissing) choroidal bullae and visual acuity…

AdultChoroid Hemorrhagemedicine.medical_specialtyCongenital glaucomagenetic structuresRemission SpontaneousVisual AcuityGlaucomaSuprachoroidal hemorrhagePostoperative Hemorrhage03 medical and health sciences0302 clinical medicineOphthalmologyHumansMedicineIntraocular PressureDry needlingbusiness.industryGlaucomamedicine.diseaseConservative treatmentOphthalmology030221 ophthalmology & optometryDrainageFemalebusinessSclera030217 neurology & neurosurgeryJournal of Glaucoma
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Effects of Early Postfiltration Ocular Hypotony on Visual Acuity, Long-term Intraocular Pressure Control, and Posterior Segment Morphology

2001

Purpose To determine whether hypotony after filtration surgery has any influence on visual acuity and intraocular pressure (IOP) lowering. Patients and methods We prospectively investigated 43 eyes of 43 patients undergoing trabeculectomy without the use of antimetabolites for 12 months. Results The lowest postoperative IOP valued 4.9 +/- 3.6 mm Hg (range, 0-14 mm Hg). It correlated statistically significant with the IOP 6 weeks (P = 0.016), 6 months (P = 0.009), and 1 year after surgery (P = 0.027). Eyes with a deterioration of visual acuity 6 weeks after surgery had undergone a stronger postoperative hypotony (correlation with lowest postoperative IOP, P = 0.035). The mean period with an …

AdultIntraocular pressuremedicine.medical_specialtyVisual acuitygenetic structuresFundus Oculimedicine.medical_treatmentVisual AcuityGlaucomaOcular HypotensionTrabeculectomyOcular hypotonyRetinal DiseasesOphthalmologymedicineHumansTrabeculectomyProspective StudiesProspective cohort studyIntraocular Pressurebusiness.industryChoroid Diseasesmedicine.diseaseeye diseasesPosterior segment of eyeballOphthalmologyTreatment OutcomeFiltration surgerymedicine.symptombusinessGlaucoma Open-AnglePapilledemaJournal of Glaucoma
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Corneal confocal scanning laser microscopy in patients with dry eye disease treated with topical cyclosporine

2017

Purpose To investigate the effect of cyclosporine on corneal ultrastructure and on major signs and symptoms of patients with dry eye disease.Patients and methods In this prospective cohort study, patients with dry eye disease were treated with a drop of cyclosporine 0.05% twice daily. Clinical evaluation was carried out at baseline and at months 1, 3, and 6. All patients completed the Ocular Surface Disease Index (OSDI) questionnaire, and tear film break-up time (BUT), fluorescein and lissamine green staining, and Schirmer test were carried out. In vivo confocal microscopy was also performed and epithelial cellular density, keratocyte activation, and subbasal plexus morphology were assessed…

AdultMale0301 basic medicinemedicine.medical_specialtyAdministration TopicalConfocalDry Eye SyndromesGlaucomaCell CountOphthalmic SolutionFollow-Up StudieCorneaImmunosuppressive Agent03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOphthalmologyCorneamedicineOcular Surface Disease IndexFluoresceinProspective cohort studyAgedMicroscopy Confocalbusiness.industryMiddle Agedmedicine.diseaseStainingProspective StudieOphthalmologyTreatment Outcome030104 developmental biologymedicine.anatomical_structureNerve FiberchemistryCyclosporine030221 ophthalmology & optometryFemalebusinessDry Eye SyndromeHumanEye
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Distribution of Anterior Chamber Angle Width and Correlation With Age, Refraction, and Anterior Chamber Depth—The Gutenberg Health Study

2016

PURPOSE Scheimpflug imaging allows quantitative analysis of the width of the anterior chamber angle. We report the population-based distribution of the anterior chamber angle width using this noncontact imaging technique and investigate associated factors. METHODS A population-based cross-sectional study was carried out in Germany. A comprehensive ophthalmologic examination including refraction, biometry, and Scheimpflug imaging was performed. Automated measurement of the anterior chamber angle was performed in each anterior chamber quadrant. Exclusion criteria were previous ocular surgery or inadequate image quality. Association analyses were carried out to determine independently associat…

AdultMaleAnterior ChamberOcular surgeryScheimpflug principlePopulationGlaucoma610 Medicine & healthDiagnostic Techniques OphthalmologicalRefraction OcularAnterior chamber angleCornea03 medical and health sciences0302 clinical medicineRisk FactorsGermanyLens CrystallinemedicineHumans610 Medicine & healtheducationAgedSex Characteristicseducation.field_of_studybusiness.industryAge FactorsAstigmatismMiddle Agedmedicine.diseaseRefractionCross-Sectional StudiesOphthalmologic examination030221 ophthalmology & optometryFemaleGlaucoma Angle-ClosureNuclear medicinebusiness030217 neurology & neurosurgeryShallow anterior chamberInvestigative Opthalmology & Visual Science
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Goldmann Applanation Tonometry Using Sterile Disposable Silicone Tonometer Shields

1996

Abstract Purpose: Placement of a sterile single-use cover over the tonometer tip may be a convenient and safe alternative method to repeated chemical disinfection. This study was undertaken to evaluate the accuracy and performance of Goldmann applanation tonometry using a sterile disposable silicone tonometer shield over the biprism tip. Methods: The same investigator measured intraocular pressure in 120 eyes with and without the shield. The eyes were tested randomly first with either the uncovered or the covered tonometer to control for the possible effects of repeated tonometry influencing measurement differences. Readings were recorded independently in a masked fashion. Results: The intr…

AdultMaleApplanation tonometryIntraocular pressuremedicine.medical_specialtyAdolescentgenetic structuresSiliconesOcular hypertensionGlaucomaSensitivity and SpecificityGoldmann applanation tonometryChemical disinfectionTonometry Ocularchemistry.chemical_compoundSiliconeDouble-Blind MethodOphthalmologymedicineHumansChildDisposable EquipmentIntraocular PressureAgedAged 80 and overAlternative methodsbusiness.industryReproducibility of ResultsGlaucomaMiddle Agedmedicine.diseaseeye diseasesSurgeryOphthalmologychemistryEvaluation Studies as TopicInfertilityFemaleOcular Hypertensionsense organsbusinessOphthalmology
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Comparison of Dynamic Contour Tonometry and Goldmann Applanation Tonometry in Glaucoma Patients and Healthy Subjects

2006

To investigate the agreement in the measurement of intraocular pressure (IOP) obtained by dynamic contour tonometry PASCAL (DCT-PASCAL) and Goldmann applanation tonometry (GAT) in glaucoma eyes and healthy eyes with different central corneal thickness (CCT).Prospective cross-sectional study.In a randomized order, three consecutive IOP measurements were performed on 197 eyes of 107 subjects by one examiner using both DCT-PASCAL and GAT on all eyes. Furthermore, ultrasonic pachymetry was performed. The Spearman correlation coefficient (r) was determined to compare IOP readings between DCT-PASCAL and GAT. Regression-based Bland and Altman analysis was used to evaluate agreement between the ins…

AdultMaleApplanation tonometryIntraocular pressuremedicine.medical_specialtygenetic structuresEye diseaseVisual AcuityGlaucomaGoldmann applanation tonometryCorneaTonometry OcularOphthalmologyHumansMedicineProspective StudiesIntraocular PressureAgedUltrasonographyAged 80 and overbusiness.industryLimits of agreementHealthy subjectsReproducibility of ResultsGlaucomaMiddle Agedmedicine.diseaseeye diseasesOphthalmologyCross-Sectional StudiesVisual Field TestsFemaleOcular Hypertensionsense organsbusinessAmerican Journal of Ophthalmology
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Knowledge about glaucoma in the unselected population: a German survey.

2002

Purpose To determine the general population's knowledge about glaucoma. Materials and methods A representative survey of the German population was conducted in which 2,742 men and women were interviewed face to face. The sample was matched with the German population for age, sex, education, income, and other factors. Questions were asked concerning the nature, occurrence, possible risk factors, and course of glaucoma. Results Fifty-one percent of the population had an active knowledge of the term "glaucoma" and 75% had a passive knowledge of the term. Of those interviewees with a passive knowledge, glaucoma was thought to be associated with raised intraocular pressure (IOP) by 28% and loss …

AdultMaleIntraocular pressurePediatricsmedicine.medical_specialtyHealth Knowledge Attitudes Practicegenetic structuresAdolescentPopulationMEDLINEGlaucomaDiseaseGermanBlurred visionRisk FactorsSurveys and QuestionnairesmedicineHumanseducationIntraocular PressureAgedAged 80 and overeducation.field_of_studybusiness.industryMiddle Agedmedicine.diseaseeye diseaseslanguage.human_languageOphthalmologylanguageUnselected populationFemalesense organsmedicine.symptombusinessGlaucoma Open-AngleJournal of glaucoma
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Analysis of Autoantibodies Against Human Retinal Antigens in Sera of Patients with Glaucoma and Ocular Hypertension

2008

The aim of this study was to show that complex antibody patterns against retinal antigens in sera of patients with glaucoma, found in previous studies, are autoantibodies against human antigens.Sera of 179 patients were collected at the Department of Ophthalmology (University of Mainz, Germany): non-glaucomatous control patients (n=45), primary open-angle glaucoma (n=45), ocular hypertension (n=44), and normal tension glaucoma patients (n=45). The sera were tested against Western blots of human retinal antigens. IgG antibody patterns were analyzed by multivariate statistical techniques, and some significant antigens were identified by mass spectrometry.All subjects, even healthy ones, showe…

AdultMaleIntraocular pressuregenetic structuresBlotting WesternGlaucomaOcular hypertensionAutoantigensMass SpectrometryRetinaImmunoglobulin GHistonesTonometry OcularCellular and Molecular NeuroscienceAntigenNormal tension glaucomamedicineHumansIntraocular PressureAgedAutoantibodiesAged 80 and overArrestinbiologybusiness.industryAutoantibodyMiddle Agedmedicine.diseaseeye diseasesSensory SystemsOphthalmologyImmunoglobulin GImmunologybiology.proteinFemaleOcular HypertensionAntibodyCarrier ProteinsbusinessGlaucoma Open-AngleCurrent Eye Research
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Combined procedure for glaucoma and cataract: A retrospective study

1994

Abstract To ascertain the long-term effects of a triple procedure in the case of coexisting cataract and glaucoma, we did a retrospective study of 93 eyes that had cataract extraction, IOL implantation, and trabeculectomy within a ten-year period. Mean follow-up was 32.4 ± 21.9 months. Mean postoperative intraocular pressure (IOP) was significantly lower than preoperatively, even though fewer medications were being used. One year after surgery, 60% of eyes had a best corrected visual acuity of 20/40 or better with an average improvement of 3.8 Snellen lines. Patients who had had surgery four or more years before the study had the highest percentage of eyes with an IOP exceeding 22 mm Hg. Th…

AdultMaleIntraocular pressuremedicine.medical_specialtyAdolescentgenetic structuresmedicine.medical_treatmentEye diseaseVisual AcuityGlaucomaTrabeculectomyIntraocular lensCataract ExtractionOphthalmologymedicineHumansTrabeculectomyLongitudinal StudiesIntraocular PressureAgedRetrospective StudiesAged 80 and overLenses IntraocularBest corrected visual acuitybusiness.industryGlaucomaRetrospective cohort studyCombined procedureMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologyTreatment OutcomeFemaleSurgerysense organsbusinessFollow-Up StudiesJournal of Cataract and Refractive Surgery
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Prevalence of glaucoma and distribution of intraocular pressure in a population. The Casteldaccia Eye Study.

2009

IOP was measured in 1062 middle-aged and elderly subjects of a small Sicilian town, enrolled in a population based survey. The mean IOP was 15.1 +/- 3.7 mmHg without interocular or sex differences. A small but significant age-dependent increase of IOP was found. Circadian and seasonal influences were recorded: IOP was higher in the morning and in winter. The prevalence of chronic open-angle glaucoma was 1.2%, but it grew to 3.6 if only subjects aged 70 years or more were considered. IOP of 24 mmHg or more was found in 2.7%, while 4.3% of subjects showed IOP of 21 mmHg or more. This survey shows that mean IOP of the Mediterranean population studied is similar to the IOP found in other epidem…

AdultMaleIntraocular pressuremedicine.medical_specialtyAginggenetic structuresPopulationOcular hypertensionGlaucomaAge DistributionOphthalmologymedicinePrevalenceHumansCircadian rhythmSex DistributioneducationPopulation based surveySicilyIntraocular PressureMorningAgedAged 80 and overeducation.field_of_studybusiness.industryGlaucomaMiddle Agedmedicine.diseaseeye diseasesCircadian RhythmOphthalmologyAge distributionFemaleOcular Hypertensionsense organsSeasonsbusinessActa ophthalmologica Scandinavica
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