Search results for "Gram Negative"
showing 3 items of 13 documents
Cellular effects of bacterial N-3-Oxo-dodecanoyl-L-Homoserine lactone on the sponge Suberites domuncula (Olivi, 1792): insights into an intimate inte…
2014
International audience; Sponges and bacteria have lived together in complex consortia for 700 million years. As filter feeders, sponges prey on bacteria. Nevertheless, some bacteria are associated with sponges in symbiotic relationships. To enable this association, sponges and bacteria are likely to have developed molecular communication systems. These may include molecules such as N-acyl-L-homoserine lactones, produced by Gram-negative bacteria also within sponges. In this study, we examined the role of N-3-oxododecanoyl-L-homoserine lactone (3-oxo-C12-HSL) on the expression of immune and apoptotic genes of the host sponge Suberites domuncula. This molecule seemed to inhibit the sponge inn…
Pdl1 Is a Putative Lipase that Enhances Photorhabdus Toxin Complex Secretion
2012
The Toxin Complex (TC) is a large multi-subunit toxin first characterized in the insect pathogens Photorhabdus and Xenorhabdus, but now seen in a range of pathogens, including those of humans. These complexes comprise three protein subunits, A, B and C which in the Xenorhabdus toxin are found in a 4∶1∶1 stoichiometry. Some TCs have been demonstrated to exhibit oral toxicity to insects and have the potential to be developed as a pest control technology. The lack of recognisable signal sequences in the three large component proteins hinders an understanding of their mode of secretion. Nevertheless, we have shown the Photorhabdus luminescens (Pl) Tcd complex has been shown to associate with th…
Piogēno infekciju gramnegatīvie aģenti ķirurģiskajā klīnikā
2016
Ievads: Ar veselības aprūpi saistītu infekciju izplatība turpina pieaugt visā pasaulē un tiek lēsts, ka tās būs 5-10% stacionārā iegūtās un ar augstāko līmeni ķirurģijas un intensīvās terapijas nodaļās. Tika veikts pētījums ar nozokomiālām infekcijām divās slimnīcās Latvijā. Šajā pētījumā bija 17.5% nozokomiālo infekciju gadījumu (226 pacientiem no 1291). Mērķis: Pētījuma mērķis ir analizēt gram-negatīvo strutainu infekciju sastopamību Traumatoloģijas un Ortopēdijas slimnīcā. Materiāli un metodes: Retrospektīvs pētījums ietver paraugus no pacientiem, kuri ieradās uz plānotu operāciju TOS laika posmā no 02.12.2014. līdz 28.08.205. Mikroorganismi tika izolēti no operācijas vietas, brūces, āda…