Search results for "Grandes"
showing 10 items of 60 documents
¡Los de Múnich, a la horca!
2009
Vicente Verdú y nuestras miserias
2006
Primary multifocal anaplastic large cell lymphoma with eyelid involvement: a case report
2019
ABSTRACT Ocular adnexal involvement in CD30+ lymphoproliferative disorders is rare. We report the case of a 73-year-old woman with a relapsing primary cutaneous anaplastic large cell lymphoma on her eyelid. A systemic extension study excluded extracutaneous involvement. Systemic chemotherapy resulted in an optimal response, with complete regression of the cutaneous lesions. There has been no recurrence during the 2 years of follow-up. RESUMO O acometimento ocular adicional nos distúrbios linfoproliferativos CD30+ é raro. Relatamos o caso de uma mulher de 73 anos com linfoma de grandes células anaplásicas primárias recidivantes em sua pálpebra. A avaliação sistêmica excluiu envolvimento extr…
El último intelectual (y 4). Un modelo
2007
Evaluation of the impact of therapeutic management on the survival and quality of life of patients with follicular lymphoma or diffuse large B cell l…
2014
In France, hematologic malignancies, which are the sixthmost common cancers, are amajor public healthproblem. This work aimed to study the impact of the therapeutic management on survival and healt-relatedquality of life (HRQoL) in patients with these hematologic malignancies. The first objective of this work is topresent an overview of the epidemiology of lymphoid malignancies with a study of changes in the incidenceand net survival in the Côte d’Or department between 1980 and 2009. The incidence, which has increased since1980, seems to have stabilized since the 2000s for some entities, including follicular lymphoma (FL) and diffuselarge B-cell lymphoma (DLBCL). Overall, we observed an imp…
La abominación que no cesa
2009
Las grandes Exposiciones en Europa: 1992-2002. Efectos duraderos sobre la ciudad y apropiación por parte de la ciudadanía.
2012
This paper studies the influence of great contemporary Expositions on the transformation of cities and of territories, developing some aspects we consider relevant of these events: their growing relevance in urban contemporary politics and the urban and architectural project as creator of the regeneration of abandoned or obsolete areas. Against the short duration of these events, the positive and negative effects, like the definition of new urban and territorial domains, the modernization of infrastructures and services, the impulse of private stakeholders toward building lands and the consolidation of City-Brand in tourism nets among others, have a much longer duration, and depend on the u…
Functional characterisation of the first HSP110 inhibitors.
2023
Heat shock proteins are molecular chaperones highly expressed in haematological malignancies. My laboratory has shown that the heat shock protein HSP110 is a new and important therapeutic target In colorectal cancer and in non-Hodgkin's lymphoma. As there were no existing inhibitors of HSP110, a screening strategy of a chemical library was carried out and allowed the identification of two molecules capable of specifically inhibiting the chaperone activity of HSP110. My thesis objective was to characterise and functionally validate these newly identified molecules in diffuse large cell B lymphomas. I have shown that one of these molecules limits the interaction of HSP110 with the SYK signall…
Pasquali, P. - Héritocratie. Les élites, les grandes écoles et les mésaventures du mérite
2021
« L’héritocratie n’est pas une méritocratie dégénérée, ou une technocratie aux bases élargies ; ce concept désigne l’ensemble des capacités d’agir, individuelles ou collectives, que les grandes écoles et, plus largement, les filières d’élite mettent en œuvre à chaque période pour conserver ou accroître leurs privilèges et leur légitimité face aux crises, critiques ou réformes susceptibles d’aller contre leurs intérêts. Plus précisément, il renvoie aux stratégies de résistance et de promotion ...