Search results for "Granulocytosis"

showing 2 items of 12 documents

Comparative effects of UVA and UVB irradiation on the immune system of fish.

2000

Aquatic organisms can be harmed by the current levels of solar ultraviolet radiation. We have recently shown that exposure of fish to UVB irradiation alters the functioning of the fish immune system, but the effects of UVA radiation are unknown. The present study continues this work by characterizing UVA irradiation-induced immunological changes in fish. Roach, a cyprinid fish, were exposed to a single dose of either UVA (3.6 J/cm2) or UVB (0.5 J/cm2) irradiation. Both irradiations suppressed transiently mitogen-stimulated proliferation of blood lymphocytes. UVA, but not UVB, decreased hematocrit, plasma protein, and plasma immunoglobulin levels and increased the proportions of blood cells …

medicine.medical_specialtyUltraviolet RaysBiophysicsCyprinidaeImmunoglobulinsHematocritLymphocyte ActivationLeukocyte CountImmune systemInternal medicinemedicineAnimalsRadiology Nuclear Medicine and imagingLymphocytesRadiationHematologyintegumentary systemRadiological and Ultrasound Technologybiologymedicine.diagnostic_testGranulocytosisBlood Proteinsmedicine.diseaseMolecular biologyBlood proteinsBlood chemistryHematocritImmunologybiology.proteinErythrocyte Countsense organsAntibodyLymphocytopeniaJournal of photochemistry and photobiology. B, Biology
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Synchronous Antithyroid Drug-Induced Agranulocytosis and Fournier Gangrene

2018

ABSTRACT: Objective: Antithyroid drugs (ATDs) such as thioimidazoles (e.g., methimazole, also called thiamazole, and carbimazole) and propylthiouracil are commonly used for the treatment of hyperthyroidism. A life-threatening reaction is agranulocytosis with an incidence of 0.1 to 0.5%. There are very few cases in the literature showing that the intake of ATDs finally led to sepsis with accompanying tissue necrosis.Methods: We present an unusual case of severe symptomatic agranulocytosis with sudden development of Fournier gangrene in a patient who was treated with ATDs for hyperthyroidism due to Graves disease.Results: A 69-year-old female was referred to our hospital with fever and a sore…

medicine.medical_specialtyendocrine system diseasesGraves' disease030209 endocrinology & metabolismGastroenterologyDiseases of the endocrine glands. Clinical endocrinologySepsis03 medical and health sciences0302 clinical medicineInternal medicinemedicineSore throat030212 general & internal medicinebusiness.industryIncidence (epidemiology)Fournier gangreneGeneral MedicineRC648-665medicine.diseaseDrug-induced agranulocytosisSurgeryCarbimazolePropylthiouracilmedicine.symptombusinessmedicine.drugAACE Clinical Case Reports
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