Search results for "Group A"

showing 10 items of 274 documents

Studies on serum groups in the Kumaon region, India

1970

A total of 469 individuals belonging to 4 endogamous groups (Brahamins, Rajputs, Doms and Tharus) from the Kumaon region (North India) were tested for Hp, Gc, Gm and Inv systems.

AdultMaleAdolescentStatistics as TopicIndian populationIndiaEuropean populationMiddle AgedBiologyNorth indiaWhite PeopleHuman geneticsPhenotypeAsian PeopleSocial ClassGenetic distanceEndogamyBlood Group AntigensGeneticsHumansMarriageMetabolic diseaseSocioeconomicsAllelesGenetics (clinical)Humangenetik
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Prevalence of human papilloma virus infection in patients with male accessory gland infection

2015

The frequency of human papillomavirus (HPV) infection in the semen of patients with male accessory gland infection (MAGI) was evaluated. One hundred infertile patients with MAGI were classified into group A: patients with an inflammatory MAGI (n = 48) and group B: patients with a microbial form (n = 52). Healthy age-matched fertile men (34.0 ± 4.0 years) made up the control group (n = 20). Amplification of HPV DNA was carried out by HPV-HS Bio nested polymerase chain reaction for the detection of HPV DNA sequences within the L1 ORF. Ten patients in group A (20.8%) and 15 patients in group B (28.8%) had a HPV infection; two controls (10.0%) had HPV infection. Patients with MAGI had a signifi…

AdultMaleHPVSemenComorbidityMAGIBiologyGroup AGroup BSemenmedicinePrevalenceHumansPapillomaviridaeInfertility MaleInflammationPapillomavirus InfectionsHPV infectionvirus diseasesObstetrics and GynecologyHPV MAGI Prevalencemedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaSpermfemale genital diseases and pregnancy complicationsProstatitisSemen AnalysisHPV; MAGI; PrevalenceReproductive MedicineMale accessory gland infectionImmunologySperm MotilityGenital Diseases Malemedicine.symptomNested polymerase chain reactionMagiDevelopmental Biology
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Cloning of the human NCNF gene.

1998

We have cloned from a cDNA library of human testis tissue the human homologue to the mouse nuclear orphan receptor NCNF (neuronal cell nuclear factor). The open reading frame encodes a protein of 480 amino acids, the sequence of which (EMBL accession no. X99975) is 98.3% identical to the mouse homologue. Northern blot analysis of adult human tissues revealed a broad pattern of tissue expression. Similar to NCNF expression in mouse testis, two transcript forms of the single copy gene are expressed in human tissues. The two transcript forms which differ only in their 3'UTR, result in human from differential polyadenylation, in mouse from alternative splicing. Based on the high level of sequen…

AdultMaleMolecular Sequence DataReceptors Cytoplasmic and NuclearBiologyBiochemistryMiceNuclear Receptor Subfamily 6 Group A Member 1Sequence Homology Nucleic AcidTestisAnimalsHumansNorthern blotAmino Acid SequenceCloning MolecularMolecular BiologyPeptide sequenceGeneCloningOrphan receptorRegulation of gene expressionBase SequencecDNA libraryAlternative splicingCell BiologyDNAMolecular biologyDNA-Binding ProteinsRepressor ProteinsAlternative SplicingGene Expression RegulationOrgan SpecificityJournal of receptor and signal transduction research
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Comparing extracorporeal shock wave lithotripsy and ureteroscopy laser lithotripsy for treatment of urinary stones smaller than 2 cm: a cost-utility …

2021

[EN] Purpose To analyze the efficiency and cost-utility profile of ureteroscopy versus shock wave lithotripsy for treatment of reno-ureteral stones smaller than 2 cm. Methods Patients treated for urinary stones smaller than 2 cm were included in this study (n = 750) and divided into two groups based on technique of treatment. To assess the cost-utility profile a sample of 48 patients (50% of each group) was evaluated. Quality of life survey (Euroqol 5QD-3L) before-after treatment was applied, Markov model was designed to calculate quality of life in each status of the patients (stone or stone-free with and without double-J stent) and to estimate the incremental cost-utility. Monte carlo sim…

AdultMaleNephrologyQuality of lifemedicine.medical_specialtyUreteral CalculiCost-Benefit AnalysisUrologymedicine.medical_treatment030232 urology & nephrologyUrologySubgroup analysisLithotripsyUrinary calculiKidney Calculi03 medical and health sciences0302 clinical medicineInternal medicineLithotripsymedicineUreteroscopyHumansUrologiaQuality-adjusted life yearsUreteroscopyAgedmedicine.diagnostic_testbusiness.industryStentMiddle AgedLithotripsy LaserLaser lithotripsyExtracorporeal shock wave lithotripsyQuality-adjusted life yearTreatment OutcomeSpain030220 oncology & carcinogenesisFemalebusiness
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Influence of ABCB1 polymorphisms upon the effectiveness of standard treatment for acute myeloid leukemia: A systematic review and meta-analysis of ob…

2015

The ABCB1 gene encodes for P-glycoprotein (P-gp), an efflux pump for a variety of xenobiotics. The role of ABCB1 polymorphisms in acute myeloid leukemia (AML) outcomes of standard chemotherapy (cytarabine plus anthracyclines) remains controversial. A systematic search was made of studies evaluating the association between ABCB1 polymorphisms 1236C>T, 2677G>T/A and 3435C>T and effectiveness variables. We found seven cohort studies (1241 patients) showing a significantly higher overall survival (OS) among carriers of the variant allele of 1236C>T at year 4 (odds ratio (OR): 1.47, 95% confidence interval (CI): 1.07-2.01), 2677G>T/A at years 4-5 (OR: 1.37, 95% CI: 1.01-1.86) and 3435C>T at year…

AdultMaleOncologymedicine.medical_specialtyATP Binding Cassette Transporter Subfamily BAdolescentSubgroup analysisCohort StudiesYoung AdultInternal medicineGeneticsmedicineHumansAnthracyclinesChildAgedAged 80 and overPharmacologyGeneticsPolymorphism Geneticbusiness.industryStandard treatmentCytarabineInfantMyeloid leukemiaOdds ratioMiddle AgedConfidence intervalLeukemia Myeloid AcuteObservational Studies as TopicTreatment OutcomeChild PreschoolMeta-analysisCytarabineMolecular MedicineFemalebusinessmedicine.drugCohort studyThe Pharmacogenomics Journal
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Missense PANK2 mutation without "eye of the tiger" sign: MR findings in a large group of patients with pantothenate kinase-associated neurodegenerati…

2011

Purpose: To present some unusual MR findings in a group of patients from the south-west of the Dominican Republic suffering from Pantothenate Kinase Associated Neurodegeneration (PKAN). Materials and Methods: Twenty patients and one preclinical case homozygous for the PANK2 mutation, 13 heterozygous gene carriers and 14 healthy volunteers were scanned prospectively using a 3 Tesla system. Results: All patients showed the typical signal reduction within the globus pallidus and the substantia nigra. A surprising finding was the absence of the bright spot (“tiger's eye”) in the medial part of the pallidum in 6 patients, but not in the preclinical case. Both fractional anisotropy (FA) and mean …

AdultMalePathologymedicine.medical_specialtyHeterozygoteInternal capsuleAdolescentMutation MissenseSubstantia nigraSensitivity and SpecificityPantothenate kinase-associated neurodegenerationWhite matterYoung AdultFractional anisotropymedicineMissense mutationHumansRadiology Nuclear Medicine and imagingGenetic Predisposition to DiseaseChildAgedPantothenate Kinase-Associated Neurodegenerationbusiness.industryBrainReproducibility of ResultsMiddle AgedPANK2medicine.diseaseMagnetic Resonance ImagingPhosphotransferases (Alcohol Group Acceptor)medicine.anatomical_structureGlobus pallidusnervous systemFemalebusinessJournal of magnetic resonance imaging : JMRI
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Sexual Function and Quality of Life in Adult Male Individuals with Exstrophy-Epispadias Complex—a Survey of the German CURE-Network

2017

Objective To investigate sexual function and quality of life (QoL) in adult male individuals with exstrophy-epispadias complex (EEC). Data from the German Network for Congenital Urorectal Malformations (CURE-Net) were used. Patients and Methods Fifty-one male participants (≥18 years) recruited by CURE-Net between 2009 and 2012 were re-contacted per mail and asked to fill out 4 questionnaires including International Index of Erectile Function (IIEF-5), Cologne Assessment of Erectile Dysfunction (KEED), the Short-Form 36 (SF-36), and one self-designed questionnaire about their medical history, current health status, and sexual experience. The SF-36 results were compared with general German po…

AdultMalePediatricsmedicine.medical_specialtyEpispadiasUrology030232 urology & nephrologyUrinary incontinenceSubgroup analysisDiagnostic Self EvaluationYoung Adult03 medical and health sciences0302 clinical medicineErectile DysfunctionQuality of lifeGermanymedicineHumansMedical historySex organGynecologybusiness.industryPenile ErectionBladder Exstrophymedicine.diseaseBladder exstrophySexual Dysfunction PhysiologicalErectile dysfunction030220 oncology & carcinogenesisQuality of Lifemedicine.symptomSexual functionbusinessUrology
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Associations between leprosy and serum protein groups

1970

Serum protein group typings were done on a sample of n=173 adult healthy Negroes from the Macua tribe in Mozambique and on n=129 leprous individuals from the same tribe. Unfortunately, the type of leprosy is not known. Whilst between leprosy and haptoglobins, transferrins and Pi proteins no associations could be observed, statistically significant associations between leprosy and ceruloplasmin resp. β2 I were found. It is pointed out that these associations should be confirmed by further research on other populations and with respect to type and process of leprosy, until biological and population genetical interpretations will be possible.

AdultMalePopulationSerum proteinBlack PeopleTribe (biology)LeprosyGeneticsmedicineHumansAlleleMetabolic diseaseeducationAllelesMozambiqueGenetics (clinical)Glycoproteinseducation.field_of_studyHaptoglobinsbiologyHaptoglobinTransferrinCeruloplasminfood and beveragesmedicine.diseaseBlack or African AmericanGenetics PopulationPhenotypeImmunologyBlood Group Antigensbiology.proteinFemaleLeprosyTrypsin InhibitorsCeruloplasminHuman Genetics
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Is there a group effect? It depends on how you ask the question: Intraclass correlations for California Psychotherapy Alliance Scale–Group items.

2014

California Psychotherapy Alliance Scale-Group (CALPAS-G) data were collected from 1,138 group sessions attended by 248 group members in 16 counseling groups. Hierarchical linear modeling (HLM) was used to derive between-groups, between-member, and between-session variance components and intraclass correlation coefficients (ICCs) for the 12 CALPAS-G items. Using Ledermann and Kenny's (2012) descriptions of variable types, we examined differences in between-groups variance for the 6 CALPAS-G items classified as "Individual" items and the 6 CALPAS-G items classified as "Group" items. A Related-Samples Wilcoxon's Signed Ranked Test showed that the ICCs for the Group items were significantly lar…

AdultMalePsychotherapistSocial PsychologyWilcoxon signed-rank testGroup effectIntraclass correlationmedicine.medical_treatmentModels Psychologicalbehavioral disciplines and activitiesCaliforniaGroup psychotherapymedicineHumansCooperative BehaviorIntraclass correlation coefficientGroup (mathematics)Multilevel modelHierarchical linear modelingGeneral MedicineVariance (accounting)Middle AgedGroup ProcessesGroup therapyTest (assessment)Psychiatry and Mental healthClinical PsychologyResearch DesignPsychotherapy GroupFemaleComponent (group theory)Group alliancePsychologySocial psychologyClinical psychologyJournal of Counseling Psychology
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A complication risk score to evaluate clinical severity of thalassaemia syndromes

2020

The thalassaemia syndromes (TS) show different phenotype severity. Developing a reliable, practical and global tool to determine disease severity and tailor treatment would be of great value. Overall, 7910 patients were analysed with the aim of constructing a complication risk score (CoRS) to evaluate the probability of developing one or more complications. Nine independent variables were included in the investigation as predictors. Logistic regression models were used for Group A [transfusion-dependent thalassaemia (TDT)], Group B [transfused non-TDT (NTDT)] and Group C (non-transfused NTDT). Statistically significant predictors included age (years), haemoglobin levels, hepatic transaminas…

AdultMalemedicine.medical_specialtyAdolescentcomplicationsthalassaemiacomplicationrisk scoreLogistic regressionSeverity of Illness IndexGroup AGroup BHemoglobinsYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinemedicineHumansprognostic modelBlood TransfusionClinical severityHemoglobinFramingham Risk ScoreEjection fractionReceiver operating characteristicbusiness.industryHematologyMiddle AgedPrognosisChelation TherapyThalassemia ...ROC Curve030220 oncology & carcinogenesisThalassemiaFemalecomplications; prognostic model; risk score; thalassaemiaComplicationbusiness030215 immunologyBritish Journal of Haematology
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