Search results for "Guide"
showing 10 items of 1478 documents
Bringing Plasmonics Into CMOS Photonic Foundries: Aluminum Plasmonics on Si$_{3}$N$_{4}$ for Biosensing Applications
2019
We present a technology platform supported by a new process design kit (PDK) that integrates two types of aluminum plasmonic waveguides with Si $_{3}$ N $_{4}$ photonics towards CMOS-compatible plasmo-photonic integrated circuits for sensing applications. More specifically, we demonstrate the fabrication of aluminum slot waveguide via e-beam lithography (EBL) on top of the Si $_{3}$ N $_{4}$ waveguide and an optimized fabrication process of aluminum plasmonic stripe waveguides within a CMOS foundry using EBL. Experimental measurements revealed a propagation length of 6.2 μm for the plasmonic slot waveguide in water at 1550 nm, reporting the first ever experimental demonstration of a plasmon…
An E-plane EBG waveguide for dispersion compensated transmission of short pulses
2007
The resolution of radar applications can significantly suffer from pulse broadening along the propagation in homogeneous hollow waveguides. The latter occurs due to the strongly dispersive nature of the fast waves in the waveguides. A low-cost solution to this problem is here proposed, employing an EBG type of waveguide, compatible with traditional E-plane fabrication techniques. By means of an example, here we demonstrate the reduction of the pulse spreading as it propagates along this type of waveguide.
Integrated optic Surface Plasmon Resonance Measurements in Glass substrates
2007
The surface plasmon resonance (SPR) technique is an optical method that can be used to measure the refractive index of organic nano-layers adsorbed on a thin metal film. Although there are many techniques for measuring biomolecular interactions, SPR-based techniques play a central role in many current biosensing experiments, since they are most suited to sensitive and quantitative kinetic measurements. Here we give some results from the analysis and numerical elaboration of SPR data regarding the flow of different solutions with refractive indexes in the range of interest (1-1.4). After a brief discussion of the principles of SPR and of waveguide fabrication technique, we give a description…
SARS-CoV-2: Impact on, Risk Assessment and Countermeasures in German Eye Banks.
2020
Introduction Since the beginning of the COVID-19 pandemic there has been some debate regarding the risk of transmission through tissue transplantation and tissue banking processes. Aim of the study To analyze the changes that SARS-CoV-2 has caused regarding the harvesting of corneal donor tissue and eye bank activities in Germany. Methods A questionnaire was provided to 26 eye banks in Germany, consisting of questions about adaptations made in the screening of potential donors and the harvesting of corneal tissue following the pandemic spread of SARS-CoV-2. Results Eighteen eye banks actively reduced recruitment of donors and two banks ceased all activity. Additional diagnostic screening wa…
Child abuse in a medical setting: Case illustrations of two variants of munchausen sindrome by proxy
2017
Munchausen syndrome is a complex type of abuse, which is often underdiagnosed or misdiagnosed in clinical practice, and has harmful consequences for children. Its relationship with child abuse, of which it is a variety, must be recognized in clinical and forensic practice. The authors report herein two observed cases of different types of Münchausen syndrome by proxy (MSbP). The first, is the most severe form of MSbP, with induced, true illness and related pathological symptoms into victim. The second case is a moderate form, much more complex to detect, in which a perpetrator parent simulates and aggravates the childâs illness. Adequate training of health professionals and investigators…
Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in child…
2016
Background: Evidence on the effects of lifestyle interventions on plasma fatty acid composition in children is limited. Objective: We investigated the effects of a dietary and physical activity intervention on plasma fatty acid composition of cholesteryl esters (CEs) and phospholipids and estimated desaturase and elongase activities in children. Design: We conducted a 2-y controlled dietary and physical activity intervention based on Finnish nutrition and physical activity recommendations in a population sample of 506 children aged 6–8 y. We assessed plasma fatty acid composition by gas chromatography and estimated desaturase and elongase activities as the ratio of product fatty acids to pr…
Faraday effect in magnetic fluids at a frequency 10GHz
2002
Abstract This work presents some results of observed Faraday effect in magnetic fluids in the centimetric region of the electromagnetic spectrum. The effect is observed when a transversal electric wave of mode H11 propagates in the circular waveguide with a magnetic fluid. The constant magnetic field was applied along the waveguide. Magnetic fluids with different concentrations of magnetite core nanoparticles suspended in tetradecane (C14H30) are used in the magnetic fields from 0 to 1500 Oe. A 160° rotation of wave polarization is obtained for a 200 mm sample.
PERCUTANEOUS US (ULTRA SOUND) GUIDED FINE NEEDLE ASPIRATION (FNA) OF ENDOTHORACIC NEOPLASM
2022
Introduction: Ultrasound (US)-guided fine needle aspiration (FNA) of percutaneous, transparietal endothoracic lesions, is a useful method in the diagnostic process for anatomopathological characterization. This sampling is a minimally invasive procedure, with a low complication rate and can be performed under loco-regional anesthesia Material and methods: We retrospectively studied (2009 to 2019) the utility of US guided transthoracic FNA in the diagnosis of suspected endothoracic lesions on 54 patients (34 men and 20 women), aged between 44 and 79 years, with pleural, pulmonary or mediastinal neoplasm viewable with an US examination. Results: The definitive diagnosis of malignant or benign…
Design of molecular imaging and theranostic agents for the detection and targeted therapy of cancers
2020
Despite significant advances in cancer detection and treatment, cancer is now the second leading cause of death worldwide. The aim of this thesis project was to design and optimize imaging agents for the diagnosis and/or therapy of various cancers.The first axis of this thesis focused on the development of a bimodal PET/fluorescence imaging agent capable of targeting neurotensin NTS1 receptors overexpressed in certain cancers. PET imaging would allow efficient detection of tumors and their metastases, while fluorescence imaging would facilitate the evaluation of tumor margins during surgery. Several compounds were synthesized, labelled with gallium-68 and studied in preclinical studies in a…
Evaluation of near-Infrared fluorescence-conjugated peptides for visualization of human epidermal receptor 2-overexpressed gastric cancer.
2021
338 Background: HER2 is highly overexpressed in many kinds of cancers with a poor prognosis. Recently, near-infrared (NIR) fluorescence-based imaging is a growing field for both pre-clinical and clinical application. In this study, we aimed to synthesize Human Epidermal Receptor2 (HER2)-specific near-infrared (NIR) fluorescence probes and evaluate their applicability in cancer-specific image-guided surgeries using an animal model. Methods: An NIR dye emitting light of 800 nm (IRDye800CW, Li-COR, USA) was conjugated to trastuzumab and HER2-specific affibody using click mechanism. HER2 affinity was assessed by the surface plasmon resonance technique. HER2 positive/negative gastric cancer cel…