Search results for "H-3"

showing 10 items of 34 documents

Postnatal development of the dopaminergic signaling involved in the modulation of intestinal motility in mice

2015

Background:Since antidopaminergic drugs are pharmacological agents employed in the management of gastrointestinal motor disorders at all ages, we investigated whether the enteric dopaminergic system may undergo developmental changes after birth.Methods:Intestinal mechanical activity was examined in vitro as changes in isometric tension.Results:In 2-d-old (P2) mice, dopamine induced a contractile effect, decreasing in intensity with age, replaced, at the weaning (day 20), by a relaxant response. Both responses were tetrodotoxin (TTX)-insensitive. In P2, dopaminergic contraction was inhibited by D1-like receptor antagonist and mimicked by D1-like receptor agonist. In 90-d-old (P90) mice, the …

0301 basic medicineAgonistmedicine.medical_specialtyGastrointestinal Diseasesmedicine.drug_classDopamineTetrodotoxinBiologySettore BIO/09 - FisiologiaEnteric Nervous SystemMice03 medical and health sciences0302 clinical medicineDopamine receptor D3DopamineInternal medicineIntestine SmallCyclic AMPmedicineAnimalsEstrenesReceptorDopaminergicReceptor antagonistPyrrolidinonesMice Inbred C57BL030104 developmental biologyEndocrinologyAnimals NewbornDopamine receptorType C PhospholipasesDideoxyadenosinePediatrics Perinatology and Child Health2345-Tetrahydro-78-dihydroxy-1-phenyl-1H-3-benzazepineSignal transductionGastrointestinal Motility030217 neurology & neurosurgerySignal Transductionmedicine.drugPediatric Research
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The Concise Guide To Pharmacology 2021/22: G Protein-Coupled Receptors

2021

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will s…

RMCytoplasmic and NuclearComputer scienceDatabases PharmaceuticalHumans; Ion Channels; Ligands; Receptors Cytoplasmic and Nuclear; Receptors G-Protein-Coupled; Databases Pharmaceutical; PharmacologyReceptors Cytoplasmic and NuclearIN-VITRO CHARACTERIZATIONPharmacologyLigandsIon ChannelsNORSlaw.inventionReceptors G-Protein-CoupledG-Protein-CoupledDatabases03 medical and health sciencesCALCIUM-SENSING RECEPTOR0302 clinical medicineDELTA-OPIOID RECEPTORlawSummary informationReceptorsHumansHISTAMINE H-3 RECEPTORFATTY-ACID RECEPTORMETABOTROPIC GLUTAMATE-RECEPTOR030304 developmental biologyG protein-coupled receptorPharmacologyGONADOTROPIN-RELEASING-HORMONE0303 health sciencesClinical pharmacologyFORMYL PEPTIDE RECEPTORMUSCARINIC ACETYLCHOLINE-RECEPTOR3. Good health317 Pharmacy030220 oncology & carcinogenesisPharmaceuticalNEGATIVE ALLOSTERIC MODULATORCatalytic receptors
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Effects of Fenoldopam on Intracranial Pressure and Hemodynamic Variables at Normal and Elevated Intracranial Pressure in Anesthetized Pigs

1994

Fenoldopam (FE), a dopamine DA1-receptor agonist, has been introduced for treatment of arterial hypertension and heart failure and for preservation of renal function. Vasodilators are generally assumed to affect all vascular beds including the cerebral circulation. We have evaluated effects of FE-induced (4 micrograms.kg-1.min-1) arterial hypotension on intracranial pressure (ICP) and intraocular pressure (IOP) under conditions of normal and increased intracranial elastance. ICP and IOP responses to hypertension were tested by infusion of angiotensin II (15 micrograms.kg-1.min-1), and the response to hypercapnia was tested by elimination and reintegration of soda lime canisters in the breat…

MaleCentral Venous PressureIntracranial PressureFenoldopamSwineDopamine AgentsHemodynamicsBlood PressureAnesthesia GeneralFenoldopamCerebral autoregulationHypercapniaCerebral circulationCerebrospinal fluidHeart RateAnimalsMedicinePulmonary Wedge PressureAntihypertensive AgentsIntraocular PressureIntracranial pressurePseudotumor CerebriDose-Response Relationship Drugbusiness.industryAngiotensin IIHemodynamicsAngiotensin IIAnesthesiology and Pain MedicineCerebrovascular CirculationAnesthesiaHypertensionFemaleOcular HypertensionVascular ResistanceSurgery2345-Tetrahydro-78-dihydroxy-1-phenyl-1H-3-benzazepineNeurology (clinical)medicine.symptombusinessHypercapniamedicine.drugJournal of Neurosurgical Anesthesiology
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Response to dopamine agonists of the rat isolated uterus.

1993

1. Quinpirole did not produce any effect in isolated uterus from oestrogenized rats even when it is contracted by KCl (37 mM). 2. Fenoldopam produced a relaxant effect on rat isolated uterus contracted by KCl which was not significantly modified by SCH 23390. 3. Reserpine decreased the effect of the lowest doses of fenoldopam. In reserpinized rats, propranolol (10(-9), 10(-8), 10(-7) M) antagonized the effect of the lowest doses of fenoldopam and neither SCH 23390, sulpiride nor ranitidine modified the effect of fenoldopam. 4. The results confirm our previous finding that DA1-receptors are not functional in our preparation. The effect of fenoldopam was partially due to a catecholamine-relea…

medicine.medical_specialtySerotoninQuinpiroleReserpineFenoldopamDopamine AgentsUterusPropranololPharmacologyFenoldopamIn Vitro TechniquesDopamine agonistchemistry.chemical_compoundUterine ContractionQuinpiroleCatecholaminesInternal medicineReceptors Adrenergic betamedicineAnimalsErgolinesRats WistarPharmacologySCH-23390ChemistryReserpineAcetylcholineRatsEndocrinologymedicine.anatomical_structureFemale2345-Tetrahydro-78-dihydroxy-1-phenyl-1H-3-benzazepineSulpiridemedicine.drugGeneral pharmacology
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Hypernuclear spectroscopy of products from Li-6 projectiles on a carbon target at 2 A GeV

2013

WOS: 000322848900009

Nuclear reaction(Li-6E=2 GeV/nucleonNuclear and High Energy PhysicsMaximum likelihoodWEAK DECAYFOS: Physical sciencesLIFETIMET-1/2. Compared with other datadeduced Lambda massC-12(LAMBDA)H-4)T-1/2measured Lambda H-3H-4 Lambda-hypernuclei invariant mass distribution T-1/2measured LambdaInvariant massNuclear Experiment (nucl-ex)LIGHT HYPERFRAGMENTSSpectroscopyNuclear ExperimentX)PhysicsH-4 Lambda-hypernuclei invariant mass distributionH-3ProjectileSignificance valueslifetime measurementdeduced Lambda mass H-3H-4 Lambda-hypernuclei mass T-1/2. Compared with other data lifetime measurementNUCLEAR REACTIONS C(Li-6Decay timeLAMBDA-HYPERNUCLEIAtomic physicst)NUCLEAR REACTIONS C(Li-6 X) (Li-6 t) (Li-6 H-4) E=2 GeV/nucleonH-4 Lambda-hypernuclei massHypertritonRELATIVISTIC HYPERNUCLEINuclear Physics A
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Zvaigžņotā Debess: 2004/05, Ziema

2004

Contents: Ņ.Ozoliņa. Earthquakes in Latvia ; I.Daube. Space Craft “Ranger-7” ; M. Gailis. Moon Investigation in Riga ; J.Tambergs. Problems of Dialogue between Quantum Mechanics and Theology (concluded) ; Z Alksne, A.Alksnis. Ultra-Cool Dwarf Pair Weighed ; A.Balklavs. Successful Hunt of Protostars ; A.Balklavs. Silhouette of a Black Hole ; A.Balklavs. A Distant Giant Quasar ; A.Balklavs. Cosmic Objects in Captivating Photos – 3 ; J.Freimanis. Extragalactic Planetary Nebulae ; J.Jaunbergs. Cassini Enters the Saturnian System ; D.Krieviņš. Space Launchers of Early XXI Century. The Commonwealth of Independent States (CIS) ; J.Bārzdiņš. Professor Rusins-Martins Freivalds on the Path of Science…

Novembra kāvi Baltijas debesīsGalēji auksto punduru sistēma 2MASSW J0746425+2000321Herbiga-Haro objekti HH-30 HH-34 HH-47Krustvārdu mīklaLīgatnes meteorīts – hipotēzeProtozvaigznesPlanetārie miglāji – NGC 2392 (Eskimosa miglājs) NGC 6369 (Spociņa miglājs)Starptautiskā komandu olimpiāde “Baltijas ceļš – 2003” – uzdevumu atrisinājumiRisina lasītājsNASA Genesis – Saules vēja paraugiLU profesors Rūsiņš-Mārtiņš FreivaldsZemestrīces LatvijāBlumbaha spoguļteleskops BSTPirmās galaktikasCassini misija Saturna sistēmāJakobs Juliuss ZeibotsJupitera pavadoņa Jo putekļiRīgas topogrāfiskā uzmērīšanaSavādnieki eksaktajās zinātnēs – Dž.Maksvels O.Sevisaids H.Hercs V.Pauli V.Heizenbergs B.Mandelbrots A.Vītols J.Vītols G.Šipovs A.AkimovsMeteorītu panspermijaPlanetārie miglāji N52 N66 N192 SMP93 Lielajā Magelāna MākonīVenēras un Merkura aizklāšanāsKosmiskie transportlīdzekļi – NVSAstronomiskās parādības - 2005Melnais caurums – siluetsKalenaisa – “Hebridu Stounhendža”Planētu redzamības kompleksā diagramma 2005Zvaigžņu lietus novembrīESA Smart-1Astronomiskās parādības - 2004Kvantu mehānika un teoloģijaMilzu kvazārs J1432+158Londonas universitātes Berkbeka koledža
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CCDC 2106005: Experimental Crystal Structure Determination

2021

Related Article: Essi Taipale, Marcel Siepmann, Khai-Nghi Truong, Kari Rissanen|2021|Chem.-Eur.J.|27|17412|doi:10.1002/chem.202103152

bis(1-methyl-1H-31-benzimidazol-3-yl)iodanium hexafluorophosphateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2044705: Experimental Crystal Structure Determination

2021

Related Article: Sergiu Calancea, Luca Carrella, Teodora Mocanu, Vladimir Sadohin, Mihai Raduca, Iacob Gutu, Julio C. Rocha, Maria G. F. Vaz, Eva Rentschler, Marius Andruh|2021|Eur.J.Inorg.Chem.|2021|567|doi:10.1002/ejic.202000954

bis(mu-4455-tetramethyl-3-oxo-2-(5-phenyl-1H-pyrazol-4-yl)-45-dihydro-1H-3-imidazol-1-oxyl)-hexakis(111555-hexafluoroacetylacetonato)-di-gadolinium(iii)Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 160805: Experimental Crystal Structure Determination

2001

Related Article: E.Aiello, S.Aiello, F.Mingoia, A.Bacchi, G.Pelizzi, C.Musiu, M.G.Setzu, A.Pani, P.La Colla, M.E.Marongiu|2000|Bioorg.Med.Chem.|8|2719|doi:10.1016/S0968-0896(00)00211-X

3-(5-Methyl-4-nitroso-1-propyl-1H-3-pyrazolyl)-5-methylisoxazoleSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2106008: Experimental Crystal Structure Determination

2021

Related Article: Essi Taipale, Marcel Siepmann, Khai-Nghi Truong, Kari Rissanen|2021|Chem.-Eur.J.|27|17412|doi:10.1002/chem.202103152

bis(1-ethyl-1H-31-benzimidazol-3-yl)iodanium hexafluorophosphateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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