Search results for "H-3"

showing 10 items of 34 documents

Postnatal development of the dopaminergic signaling involved in the modulation of intestinal motility in mice

2015

Background:Since antidopaminergic drugs are pharmacological agents employed in the management of gastrointestinal motor disorders at all ages, we investigated whether the enteric dopaminergic system may undergo developmental changes after birth.Methods:Intestinal mechanical activity was examined in vitro as changes in isometric tension.Results:In 2-d-old (P2) mice, dopamine induced a contractile effect, decreasing in intensity with age, replaced, at the weaning (day 20), by a relaxant response. Both responses were tetrodotoxin (TTX)-insensitive. In P2, dopaminergic contraction was inhibited by D1-like receptor antagonist and mimicked by D1-like receptor agonist. In 90-d-old (P90) mice, the …

0301 basic medicineAgonistmedicine.medical_specialtyGastrointestinal Diseasesmedicine.drug_classDopamineTetrodotoxinBiologySettore BIO/09 - FisiologiaEnteric Nervous SystemMice03 medical and health sciences0302 clinical medicineDopamine receptor D3DopamineInternal medicineIntestine SmallCyclic AMPmedicineAnimalsEstrenesReceptorDopaminergicReceptor antagonistPyrrolidinonesMice Inbred C57BL030104 developmental biologyEndocrinologyAnimals NewbornDopamine receptorType C PhospholipasesDideoxyadenosinePediatrics Perinatology and Child Health2345-Tetrahydro-78-dihydroxy-1-phenyl-1H-3-benzazepineSignal transductionGastrointestinal Motility030217 neurology & neurosurgerySignal Transductionmedicine.drugPediatric Research
researchProduct

CCDC 1572932: Experimental Crystal Structure Determination

2020

Related Article: Błażej Dziuk, Borys Ośmiałowski, Bartosz Zarychta, Krzysztof Ejsmont, Lilianna Chęcińska|2019|Crystals|9|662|doi:10.3390/cryst9120662

23a5-triphenyl-3aH-34-dioxa-169blambda5-triaza-3alambda5-boraphenaleneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 160805: Experimental Crystal Structure Determination

2001

Related Article: E.Aiello, S.Aiello, F.Mingoia, A.Bacchi, G.Pelizzi, C.Musiu, M.G.Setzu, A.Pani, P.La Colla, M.E.Marongiu|2000|Bioorg.Med.Chem.|8|2719|doi:10.1016/S0968-0896(00)00211-X

3-(5-Methyl-4-nitroso-1-propyl-1H-3-pyrazolyl)-5-methylisoxazoleSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1572931: Experimental Crystal Structure Determination

2020

Related Article: Błażej Dziuk, Borys Ośmiałowski, Bartosz Zarychta, Krzysztof Ejsmont, Lilianna Chęcińska|2019|Crystals|9|662|doi:10.3390/cryst9120662

4-[3a-fluoro-5-(pentafluorophenyl)-3aH-34-dioxa-169blambda5-triaza-3alambda5-boraphenalen-2-yl]-NN-dimethylanilineSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

Effects of Fenoldopam on Intracranial Pressure and Hemodynamic Variables at Normal and Elevated Intracranial Pressure in Anesthetized Pigs

1994

Fenoldopam (FE), a dopamine DA1-receptor agonist, has been introduced for treatment of arterial hypertension and heart failure and for preservation of renal function. Vasodilators are generally assumed to affect all vascular beds including the cerebral circulation. We have evaluated effects of FE-induced (4 micrograms.kg-1.min-1) arterial hypotension on intracranial pressure (ICP) and intraocular pressure (IOP) under conditions of normal and increased intracranial elastance. ICP and IOP responses to hypertension were tested by infusion of angiotensin II (15 micrograms.kg-1.min-1), and the response to hypercapnia was tested by elimination and reintegration of soda lime canisters in the breat…

MaleCentral Venous PressureIntracranial PressureFenoldopamSwineDopamine AgentsHemodynamicsBlood PressureAnesthesia GeneralFenoldopamCerebral autoregulationHypercapniaCerebral circulationCerebrospinal fluidHeart RateAnimalsMedicinePulmonary Wedge PressureAntihypertensive AgentsIntraocular PressureIntracranial pressurePseudotumor CerebriDose-Response Relationship Drugbusiness.industryAngiotensin IIHemodynamicsAngiotensin IIAnesthesiology and Pain MedicineCerebrovascular CirculationAnesthesiaHypertensionFemaleOcular HypertensionVascular ResistanceSurgery2345-Tetrahydro-78-dihydroxy-1-phenyl-1H-3-benzazepineNeurology (clinical)medicine.symptombusinessHypercapniamedicine.drugJournal of Neurosurgical Anesthesiology
researchProduct

Zvaigžņotā Debess: 2004/05, Ziema

2004

Contents: Ņ.Ozoliņa. Earthquakes in Latvia ; I.Daube. Space Craft “Ranger-7” ; M. Gailis. Moon Investigation in Riga ; J.Tambergs. Problems of Dialogue between Quantum Mechanics and Theology (concluded) ; Z Alksne, A.Alksnis. Ultra-Cool Dwarf Pair Weighed ; A.Balklavs. Successful Hunt of Protostars ; A.Balklavs. Silhouette of a Black Hole ; A.Balklavs. A Distant Giant Quasar ; A.Balklavs. Cosmic Objects in Captivating Photos – 3 ; J.Freimanis. Extragalactic Planetary Nebulae ; J.Jaunbergs. Cassini Enters the Saturnian System ; D.Krieviņš. Space Launchers of Early XXI Century. The Commonwealth of Independent States (CIS) ; J.Bārzdiņš. Professor Rusins-Martins Freivalds on the Path of Science…

Novembra kāvi Baltijas debesīsGalēji auksto punduru sistēma 2MASSW J0746425+2000321Herbiga-Haro objekti HH-30 HH-34 HH-47Krustvārdu mīklaLīgatnes meteorīts – hipotēzeProtozvaigznesPlanetārie miglāji – NGC 2392 (Eskimosa miglājs) NGC 6369 (Spociņa miglājs)Starptautiskā komandu olimpiāde “Baltijas ceļš – 2003” – uzdevumu atrisinājumiRisina lasītājsNASA Genesis – Saules vēja paraugiLU profesors Rūsiņš-Mārtiņš FreivaldsZemestrīces LatvijāBlumbaha spoguļteleskops BSTPirmās galaktikasCassini misija Saturna sistēmāJakobs Juliuss ZeibotsJupitera pavadoņa Jo putekļiRīgas topogrāfiskā uzmērīšanaSavādnieki eksaktajās zinātnēs – Dž.Maksvels O.Sevisaids H.Hercs V.Pauli V.Heizenbergs B.Mandelbrots A.Vītols J.Vītols G.Šipovs A.AkimovsMeteorītu panspermijaPlanetārie miglāji N52 N66 N192 SMP93 Lielajā Magelāna MākonīVenēras un Merkura aizklāšanāsKosmiskie transportlīdzekļi – NVSAstronomiskās parādības - 2005Melnais caurums – siluetsKalenaisa – “Hebridu Stounhendža”Planētu redzamības kompleksā diagramma 2005Zvaigžņu lietus novembrīESA Smart-1Astronomiskās parādības - 2004Kvantu mehānika un teoloģijaMilzu kvazārs J1432+158Londonas universitātes Berkbeka koledža
researchProduct

Hypernuclear spectroscopy of products from Li-6 projectiles on a carbon target at 2 A GeV

2013

WOS: 000322848900009

Nuclear reaction(Li-6E=2 GeV/nucleonNuclear and High Energy PhysicsMaximum likelihoodWEAK DECAYFOS: Physical sciencesLIFETIMET-1/2. Compared with other datadeduced Lambda massC-12(LAMBDA)H-4)T-1/2measured Lambda H-3H-4 Lambda-hypernuclei invariant mass distribution T-1/2measured LambdaInvariant massNuclear Experiment (nucl-ex)LIGHT HYPERFRAGMENTSSpectroscopyNuclear ExperimentX)PhysicsH-4 Lambda-hypernuclei invariant mass distributionH-3ProjectileSignificance valueslifetime measurementdeduced Lambda mass H-3H-4 Lambda-hypernuclei mass T-1/2. Compared with other data lifetime measurementNUCLEAR REACTIONS C(Li-6Decay timeLAMBDA-HYPERNUCLEIAtomic physicst)NUCLEAR REACTIONS C(Li-6 X) (Li-6 t) (Li-6 H-4) E=2 GeV/nucleonH-4 Lambda-hypernuclei massHypertritonRELATIVISTIC HYPERNUCLEINuclear Physics A
researchProduct

The Concise Guide To Pharmacology 2021/22: G Protein-Coupled Receptors

2021

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will s…

RMCytoplasmic and NuclearComputer scienceDatabases PharmaceuticalHumans; Ion Channels; Ligands; Receptors Cytoplasmic and Nuclear; Receptors G-Protein-Coupled; Databases Pharmaceutical; PharmacologyReceptors Cytoplasmic and NuclearIN-VITRO CHARACTERIZATIONPharmacologyLigandsIon ChannelsNORSlaw.inventionReceptors G-Protein-CoupledG-Protein-CoupledDatabases03 medical and health sciencesCALCIUM-SENSING RECEPTOR0302 clinical medicineDELTA-OPIOID RECEPTORlawSummary informationReceptorsHumansHISTAMINE H-3 RECEPTORFATTY-ACID RECEPTORMETABOTROPIC GLUTAMATE-RECEPTOR030304 developmental biologyG protein-coupled receptorPharmacologyGONADOTROPIN-RELEASING-HORMONE0303 health sciencesClinical pharmacologyFORMYL PEPTIDE RECEPTORMUSCARINIC ACETYLCHOLINE-RECEPTOR3. Good health317 Pharmacy030220 oncology & carcinogenesisPharmaceuticalNEGATIVE ALLOSTERIC MODULATORCatalytic receptors
researchProduct

CCDC 247963: Experimental Crystal Structure Determination

2005

Related Article: H.Kivela, Z.Zalan, P.Tahtinen, R.Sillanpaa, F.Fulop, K.Pihlaja|2005|Eur.J.Org.Chem.|2005|1189|doi:10.1002/ejoc.200400611

Space GroupCrystallography(2R*4aS*8aS*)-1-methyl-2-phenoxyoctahydro-2H-312-benzoxazaphosphinine 2-oxideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 994085: Experimental Crystal Structure Determination

2015

Related Article: Christoph Reiter, Tony Fröhlich, Maen Zeino, Manfred Marschall, Hanife Bahsi, Maria Leidenberger, Oliver Friedrich, Barbara Kappes, Frank Hampel, Thomas Efferth, Svetlana B. Tsogoeva|2015|Eur.J.Med.Chem.|97|164|doi:10.1016/j.ejmech.2015.04.053

Space GroupCrystallography11'-bis(((369-trimethyldecahydro-12H-312-epoxypyrano[43-j][12]benzodioxepin-10-yl)oxy)carbonyl)ferrocene dichloromethane solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct