Search results for "HAp"

STUDY ON ISOLATED MICROSPORE CULTURE IN CITRUS SINENSIS L. OSBECK CV. MORO, A BLOOD ORANGE CULTIVAR

2014

In vitro tissue culture represents a useful support for the advancement of Citrus breeding and propagation. Haploidy technology, that is the single-step development of complete homozygous genotypes from heterozygous parents through gametic embryogenesis, has already a huge impact on many relevant crops, representing an integral part in their breeding programmes (Germanà 2011a; 2011b). In order to increase the number of genotypes responding to gametic embryogenesis, in vitro isolated microspore culture of Citrus sinensis L. Osbeck cv. Moro, has been carried out, investigating the influence of the culture medium composition, and, particularly, of the plant growth regulator types and concentra…

La capilla de la Virgen de Campanar en Valencia: tradición popular erigida en erudita retórica visual

2018

This chapel forms part of the parochial church of Campanar, which belongs to the municipality of Valencia. The Virgen de Campanar (Virgin of Campanar) is an image executed in alabaster, discovered on the subfloor of the church of this place on February 19th, 1596, by some construction workers who were undertaking some remodeling at that time. From that moment forward it began to be worshipped by the masses as a miraculous image. Among its alleged properties we find the mysterious fact that powder from its plaster had miraculous effects: it was taken dissolved in water to cure the sick or to assure a healthy birth for pregnant women, and it even calmed storms at sea if it was thrown into the…

Subject, World and Value

2010

El punto de partida del artículo es el siguiente: Wittgenstein determinó su propósito de trazar un límite a la expresión lingüística del pensamiento sirviéndose, en cierta manera, de la distinción entre representación y voluntad con que Schopenhauer había reinterpretado la distinción kantiana entre el fenómeno y la cosa en sí. Al igual que Schopenhauer, Wittgenstein sostiene que el mundo de la ciencia corresponde al fenómeno, al mundo como ‘representación’, al mundo de los hechos; e igualmente considera que todo cuanto tiene que ver con los asuntos de máxima importancia y valor para nosotros —el sentido de nuestra existencia o de la existencia del mundo, la relación entre el sujeto de la vo…

Topical Application of Glycolipids from Isochrysis galbana Prevents Epidermal Hyperplasia in Mice

2017

Chronic inflammatory skin diseases such as psoriasis have a significant impact on society. Currently, the major topical treatments have many side effects, making their continued use in patients difficult. Microalgae have emerged as a source of bio-active molecules such as glycolipids with potent anti-inflammatory properties. We aimed to investigate the effects of a glycolipid (MGMG-A) and a glycolipid fraction (MGDG) obtained from the microalga Isochrysis galbana on a TPA-induced epidermal hyperplasia murine model. In a first set of experiments, we examined the preventive effects of MGMG-A and MGDG dissolved in acetone on TPA-induced hyperplasia model in mice. In a second step, we performed…

Cellular and molecular mechanisms in the induction phase of contact sensitivity.

1995

During the induction phase of contact sensitivity, hapten-specific Th1 cells are primed by epidermal Langerhans cells. These Langerhans cells present hapten on MHC class II molecules and provide costimulatory signals. This presentation discusses the induction of cytokines in Langerhans cells and keratinocytes by haptens and their regulatory effects on contact sensitivity. Haptens were painted on the skin of normal BALB/c mice and epidermal cells were prepared at various times thereafter. Langerhans cell-derived interleukin (IL)-1 beta mRNA was observed as early as 15 min after hapten paining. In keratinocytes, tumor necrosis factor-alpha, IL-1 alpha, IP-10, MIP-2 and IL-10 were found to be …

Different integrins mediate cell spreading, haptotaxis and lateral migration of HaCaT keratinocytes on fibronectin

2000

Collaborative role of various fibronectin-binding integrins (alpha5beta1, alphavbeta1 and alphavbeta6) as mediators of cell adhesion and migration on fibronectin was studied using cultured HaCaT keratinocytes. This cell line spontaneously expressed all three fibronectin-binding integrins. In addition, the expression of alphavbeta6 integrin was strongly and specifically upregulated by transforming growth factor-beta1 (TGFbeta1) whereas the amount of other integrins remained practically unchanged on the cell surface. Adhesion, spreading and motility of HaCaT keratinocytes on fibronectin were promoted by TGFbeta1. Based on antibody blocking experiments, both untreated and TGFbeta1-treated HaCa…

Raising Energy Saving Awareness Through Educational Software

2013

A study that I have conducted on a sample of 395 children aged 6 to 12, from both the urban and the rural environments, shows that an increasing number of them use computer related technologies. Today there are an increasing number of web sites that inform the user of different ways to save energy and to reduce energy consumption because it is only natural that the modern information society would go online to research such topics. The development of an educational application that is focused on teaching the children about energy saving is represented on a timeline. We conducted a study in which a number of 29 children, aged between 8 and 10, use this educational application and a questionn…

The case for strategic international alliances to harness nutritional genomics for public and personal health

2005

Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene-nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need …

A comparison between three meta-modeling optimization approaches to design a tube hydroforming process

2012

Allochthony, fatty acid and mercury trends in muscle of Eurasian perch (Perca fluviatilis) along boreal environmental gradients

2022

Environmental change, including joint effects of increasing dissolved organic carbon (DOC) and total phosphorus (TP) in boreal northern lakes could potentially affects food web energy sources and the biochemical composition of organisms. These environmental stressors are enhanced by anthropogenic land-use and can decrease the quality of polyunsaturated fatty acids (PUFAs) in seston and zooplankton, and therefore, possibly cascading up to fish. In contrast, the content of mercury in fish increases with lake browning potentially amplified by intensive forestry practises. However, there is little evidence on how these environmental stressors simultaneously impact beneficial omega-3 fatty acid …