Search results for "HAp"

The Association between Cardiorespiratory Fitness and Gut Microbiota Composition in Premenopausal Women

2017

Abstract The aim of this study was to investigate the association between cardiorespiratory fitness and gut microbiota composition in premenopausal women. The participants consisted of 71 premenopausal Finnish women (aged 19–49 years). Gut microbiota were analyzed using flow cytometry, 16S rRNA gene hybridization and DNA-staining. Maximum oxygen uptake (VO₂ₘₐₓ) was assessed by respiratory gas analyzer and body composition by Bioimpdance. We found that participants with low VO₂ₘₐₓ had lower Bacteroides, but higher Eubacterium rectale-Clostridium coccoides than the high VO₂ₘₐₓ group (p < 0.05 for all). VO₂ₘₐₓ was inversely associated with EreC (r = −0.309, p = 0.01) but not with other bact…

L’isola delle città felici : riflessi d’Europa nella letteratura politica siciliana (secoli XVII-XIX)

2012

Il saggio ricostruisce il tema della felicità pubblica nella letteratura politica siciliana, mettendo in risalto l'originalità con cui soprattutto nelle opere poco note o cadute in oblio è trattato e proposto rispetto alle principali concezioni europee che si diffondono e circolano tra i secoli XVII-XIX.

HSP27 controls GATA-1 protein level during erythroid cell differentiation.

2010

AbstractHeat shock protein 27 (HSP27) is a chaperone whose cellular expression increases in response to various stresses and protects the cell either by inhibiting apoptotic cell death or by promoting the ubiquitination and proteasomal degradation of specific proteins. Here, we show that globin transcription factor 1 (GATA-1) is a client protein of HSP27. In 2 models of erythroid differentiation; that is, in the human erythroleukemia cell line, K562 induced to differentiate into erythroid cells on hemin exposure and CD34+ human cells ex vivo driven to erythroid differentiation in liquid culture, depletion of HSP27 provokes an accumulation of GATA-1 and impairs terminal maturation. More spec…

Human Hsp60 with Its Mitochondrial Import Signal Occurs in Solution as Heptamers and Tetradecamers Remarkably Stable over a Wide Range of Concentrati…

2014

It has been established that Hsp60 can accumulate in the cytosol in various pathological conditions, including cancer and chronic inflammatory diseases. Part or all of the cytosolic Hsp60 could be naive, namely, bear the mitochondrial import signal (MIS), but neither the structure nor the in solution oligomeric organization of this cytosolic molecule has still been elucidated. Here we present a detailed study of the structure and self-organization of naive cytosolic Hsp60 in solution. Results were obtained by different biophysical methods (light and X ray scattering, single molecule spectroscopy and hydrodynamics) that all together allowed us to assay a wide range of concentrations of Hsp60…

Species cohesion despite extreme inbreeding in a social spider.

2011

Colonial social spiders experience extreme inbreeding and highly restricted gene flow between colonies; processes that question the genetic cohesion of geographically separated populations and which could imply multiple origins from predecessors with limited gene flow. We analysed species cohesion and the potential for long-distance dispersal in the social spider Stegodyphus dumicola by studying colony structure in eastern South Africa and the cohesion between this population and Namibian populations previously published. Data from both areas were (re)analysed for historic demographic parameters. Eastern South African S. dumicola were closely related to an east Namibian lineage, showing coh…

‘Quit Presently the Chapel’: A Note on Setting in the Final Scene of The Winter’s Tale

2020

Lena Constante. Experiencia carcelaria y búsqueda de la palabra liberadora en lengua francesa

2016

Lena Constante (1909-2005), escritora de origen rumano, elige la lengua francesa para escribir su testimonio en las cárceles rumanas entre 1950 y 1957. Su vivencia, en un contexto de opresión totalitaria y de injusta acusación, expresa de modo somero las condiciones políticas en las que se produjeron los acontecimientos. Ahora bien, la autora desarrolla todo un conjunto de estrategias transgresoras, ligadas a la composición verbal que plasma en su obra autobiográfica L’évasion silencieuse. Trois mille jours seule dans les prisons roumaines (1990). Lejos de alcanzar la felicidad, realiza su propio camino de liberación interior frente al silencio, el aislamiento y las torturas impuestas

Cerrando un programa iconográfico. Las hijas de Job en la Capilla de la Virgen de Guadalupe en las Descalzas Reales de Madrid

2020

ABSTRACT: The Chapel of the Virgin of Guadalupe, located in the Monastery of the Royal Discalced Nuns of Madrid, features a complex iconographical program, with the Virgin and the strong women of the Old Testament as its protagonists. This program was executed by the artist Sebastián Herrera Barnuevo, and designed by one of its resident nuns, Sister Ana Dorotea de Austria. This article attempt to shed light an a rather uncommon feminine typology: that of the daughters of Job, Jemima and Keren-happuch by means of the study of the principal literary sources where they are mentioned. By this means I will offer a complete reading of the Chapel’s iconographical program, by establishing the relat…

Linkage disequilibria between mtDNA haplotypes and chromosomal arrangements in a natural population of Drosophila subobscura

2001

The association between mtDNA haplotypes and chromosomal arrangements in a natural population of Drosophila subobscura from Calvia (Balearic Islands, Spain) was studied in order to search for linkage disequilibria, in an attempt to explain the populational dynamics of the mtDNA haplotypes of this species in nature. The presence of Wolbachia was not detected. Two main haplotypes (I and II) were found, as well as a series of less common ones. The Tajima D-test seemed to indicate some kind of seasonal population bottleneck. An analysis of linkage disequilibrium and factorial analysis of correspondences detected an association between haplotype I and the J(ST) inversion and haplotype II and the…

Association of ADHD with genetic variants in the 5'-region of the dopamine transporter gene: evidence for allelic heterogeneity.

2008

Contains fulltext : 69953.pdf (Publisher’s version ) (Closed access) Multiple studies have reported an association between attention deficit hyperactivity disorder (ADHD) and the 10-repeat allele of a variable number tandem repeat (VNTR) polymorphism in the 3'-untranslated region (3'UTR) of the dopamine transporter gene (DAT1). Yet, recent meta-analyses of available data find little or no evidence for this association; although there is strong evidence for heterogeneity between datasets. This pattern of findings could arise for several reasons including the presence of relatively rare risk alleles on common haplotype backgrounds or the functional interaction of two or more loci within the g…