Search results for "HAp"
showing 10 items of 2767 documents
Metabolites from Mediterranean plants: characterization and transformation. Chemotaxonomic assessment and biological activity.
Questo progetto di ricerca ha lo scopo di ampliare le conoscenze di alcune piante appartenenti alla flora Mediterranea. Le piante da studiare sono state scelte in seguito ad un’attenta analisi bibliografica tra specie poco sudiate. La scelta è quindi ricaduta su nove specie appartenenti al genere Anthemis, due specie appartenenti al genere Pulicaria e sulle specie di Tetraclinis articulata, Salvia argentea, Ajuga tenorei, Ballota hispanica, Moluccella Spinosa e Thapsia garganica. Di esse sono stati preparati ed identificati i componenti degli oli essenziali e successivamente effettuati su di essi i saggi antibatterici. Dagli estratti delle specie di Tetraclinis articulata e Ajuga tenorei so…
Microspore Embryogenesis in Citrus
2021
This chapter deals with microspore embryogenesis in Citrus. Microspore embryogenesis allows to induce immature gametes (microspores) and to deviate them, in this case, the male one, from the normal gametophytic developmental route in the direction of the sporophytic one, yielding homozygous organisms (embryos and plants).
Chemical composition of the essential oil from Thapsia garganica L. (Apiaceae) grown wild in Sicily and its antimicrobial activity.
2015
In this study, the chemical composition of the essential oil from flowers and leaves of Thapsia garganica L. collected in Sicily was evaluated by GC and GC-MS. The main components of T. garganica flower oil (T.f.) were chamazulene (58.3%), humulene oxide II (9.0%), tricosane (8.2%) and pentacosane (8.2%). Also the oil from leaves (T.l.) was characterised by high content of chamazulene (49.2%). Other abundant metabolites were 1,4-dimethylazulene (18.5%), (E)-phytol (6.3%) and neophytadiene (5.1%). The comparison with other studied oils of genus Thapsia is discussed. Antimicrobial activity against several micro-organisms, including some ones infesting historical art craft, was also determined.
Mechanism in allergic contact dermatitis.
1993
Stress protein/peptide complexes derived from autologous tumor tissue as tumor vaccines.
1999
Vaccination of inbred mice with tumor-derived stress proteins hsp70, hsp90, and gp96/grp94 elicits a protective immunity to the tumor from which the vaccine was purified. There is now comprehensive experimental evidence that the antigenicity of tumor-derived hsp70, hsp90, and gp96 preparations results from diverse arrays of endogenous peptide antigens complexed with these stress proteins. Vaccination with tumor-derived stress protein/peptide complexes leads to their uptake and processing by professional antigen-presenting cells and to presentation of associated tumor peptide antigens to cytotoxic T cells. This induces a tumor-specific cytotoxic T cell response. The attractiveness of the con…
Mycobacterial antigen(s) induce anergy by altering TCR- and TCR/CD28-induced signalling events: insights into T-cell unresponsiveness in leprosy.
2009
Present study investigates the role of Mycobacterium leprae (M. leprae) antigens on TCR- and TCR/CD28-induced signalling leading to T-cell activation and further correlates these early biochemical events with T-cell anergy, as prevailed in advanced stages of leprosy. We observed that both whole cell lystae (WCL) and soluble fraction of M. leprae sonicate (MLSA) not only inhibited TCR, thapsigargin and ionomycin induced calcium fluxes by diminishing the opening of calcium channels, but also TCR- or TCR/CD28-induced proximal signalling events like phosphorylation of Zap-70 and protein kinase-C (PKC) activity. Study of TCR- and TCR/CD28-induced downstream signals revealed that M. leprae antige…
On the Left Ventricular Remodeling of Patients with Stenotic Aortic Valve: A Statistical Shape Analysis
2021
The left ventricle (LV) constantly changes its shape and function as a response to pathological conditions, and this process is known as remodeling. In the presence of aortic stenosis (AS), the degenerative process is not limited to the aortic valve but also involves the remodeling of LV. Statistical shape analysis (SSA) offers a powerful tool for the visualization and quantification of the geometrical and functional patterns of any anatomic changes. In this paper, a SSA method was developed to determine shape descriptors of the LV under different degrees of AS and thus to shed light on the mechanistic link between shape and function. A total of n=86 patients underwent computed tomography (…
Statistical shape analysis of ascending thoracic aortic aneurysm: Correlation between shape and biomechanical descriptors
2020
An ascending thoracic aortic aneurysm (ATAA) is a heterogeneous disease showing different patterns of aortic dilatation and valve morphologies, each with distinct clinical course. This study aimed to explore the aortic morphology and the associations between shape and function in a population of ATAA, while further assessing novel risk models of aortic surgery not based on aortic size. Shape variability of n = 106 patients with ATAA and different valve morphologies (i.e., bicuspid versus tricuspid aortic valve) was estimated by statistical shape analysis (SSA) to compute a mean aortic shape and its deformation. Once the computational atlas was built, principal component analysis (PCA) allow…
Two mitochondrial haplotypes inPterochloroides persicae(Hemiptera: Aphididae: Lachninae) associated with different feeding sites
2012
Pterochloroides persicae (Cholodkovsky) is an aphid species belonging to the subfamily Lachninae that uses different members of Rosaceae (specially Prunus spp.) as hosts. Partial sequences from the mitochondrial cytochrome c oxidase 1 (COI) and the nuclear long-wave opsin genes were obtained for approximately 100 P. persicae aphid individuals sampled from 34 colonies collected mainly in Tunisia and other Mediterranean locations. The variability found at the mitochondrial locus revealed the presence of two maternal haplotypes in the studied area that differed in a single nucleotide. The nuclear gene analyzed, however, failed to reveal any variability in this species. The variability found at…
Note citotassonomiche sul genere Thapsia L. (Apiaceae)
2008
This study aims to clarify the taxonomic states and relations within the genus Thapsia from the Mediterranean area, with particular interest to the populations growing in Sicily. The results of morphological and karyological investigations on living plants, combined with herbarium surveys and literature data, allowed us to define an updated taxonomic profile of the genus Thapsia, with the description of a new species from the island of Lampedusa (SW Sicily), named T. pelagica. Moreover a new taxonomic combination is proposed for the populations of Peloritani Mts. (NE Sicily), which are here treated as subspecies messanensis of T. garganica.