Search results for "HAp"
showing 10 items of 2767 documents
Neurons of the dentate molecular layer in the rabbit hippocampus.
2012
The molecular layer of the dentate gyrus appears as the main entrance gate for information into the hippocampus, i.e., where the perforant path axons from the entorhinal cortex synapse onto the spines and dendrites of granule cells. A few dispersed neuronal somata appear intermingled in between and probably control the flow of information in this area. In rabbits, the number of neurons in the molecular layer increases in the first week of postnatal life and then stabilizes to appear permanent and heterogeneous over the individuals' life span, including old animals. By means of Golgi impregnations, NADPH histochemistry, immunocytochemical stainings and intracellular labelings (lucifer yellow…
La Cappella Reale di Palermo all’incrocio tra fede e potere. Musica, cerimonia e musicisti durante il viceregno spagnolo (secc. XVII-XVIII)
2021
Il contributo intende considerare il rapporto tra musica e potere attraverso una delle più importanti istituzioni del vicereame spagnolo nella penisola italiana, la Cappella Reale di San Pietro, comunemente nota come Cappella Palatina. La partecipazione alle grandi cerimonie di stato di Sei e Settecento, in particolare funerali e autodafé, sottolinea il ruolo dei musicisti della Palatina nel consolidare l’immagine del viceré e dell’identità regia in un contesto geograficamente lontano. Studi recenti hanno peraltro confermato che nelle istituzioni ecclesiastiche erano proprio gli esecutori della Cappella Reale a essere ingaggiati per suonare e cantare. Una più attenta ricostruzione dell’atti…
Revisiting the happy-productive worker thesis from a eudaimonic perspective: a systematic review
2021
The happy-productive worker thesis (HPWT) is considered the Holy Grail of management research, and it proposes caeteris paribus, happy workers show higher performance than their unhappy counterparts. However, eudaimonic well-being in the relationship between happiness and performance has been understudied. This paper provides a systematized review of empirical evidence in order to make a theoretical contribution to the happy-productive worker thesis from a eudaimonic perspective. Our review covers 105 quantitative studies and 188 relationships between eudaimonic well-being and performance. Results reveal that analyzing the eudaimonic facet of well-being provides general support for the HPWT…
Chaperones: General Characteristics and Classifications
2013
This chapter presents the classification of chaperones, their molecular properties among which that of forming functional complexes involving various molecules, and their distribution inside and outside the cell. The chaperone genes in the human genome are listed and briefly described, focusing on the small heat-shock proteins (sHsp), Hsp60, Hsp70, and Hsp90, and mentioning all others known. The chapter also introduces the concept of chaperoning system, i.e., the physiological system of an organism which is composed of all its chaperones, co-chaperones, and chaperone co-factors.
CtsR is the master regulator of stress response gene expression in Oenococcus oeni.
2005
ABSTRACT Although many stress response genes have been characterized in Oenococcus oeni , little is known about the regulation of stress response in this malolactic bacterium. The expression of eubacterial stress genes is controlled both positively and negatively at the transcriptional level. Overall, negative regulation of heat shock genes appears to be more widespread among gram-positive bacteria. We recently identified an ortholog of the ctsR gene in O. oeni . In Bacillus subtilis , CtsR negatively regulates expression of the clp genes, which belong to the class III family of heat shock genes. The ctsR gene of O. oeni is cotranscribed with the downstream clpC gene. Sequence analysis of t…
Human chaperonin disease-causing mutations: study with a prokaryotic model.
2012
Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy
2019
The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins. Genetic proteinopathies may occur either in the presence of a normal chaperoning system, which is unable to assist the defective myelin protein in its folding and migration, or due to mutations in chaperone genes, leading to functional defects in assisting myelin maturation/migration. The latter are a subgroup of genetic chaperonopathies causing demyelination. In this brief review, we describe some paradigmatic examples pertaining to the chaperonins Hsp60 (HSPD1,…
Combating Illicit Trade in Cultural Objects to Defend Peace and Security
2022
This chapter analyzes the emergence of the heritage-security nexus as a new priority in the international protection and security agenda with a focus on the threats associated with the illicit trade of cultural objects originating from conflict-ridden territories. First, it offers an overview of the existing legal framework protecting cultural objects from looting during armed conflict. It then considers how the protection of cultural property has evolved from a humanitarian law issue to one that is tied to the maintenance of international peace and security. In this latter regard, it outlines the growing concern and activity of the UN Security Council in respect of cultural heritage, inclu…
Capitolo VIII della Carta dell’ONU e modelli di azione militare regionale
2019
This contribution deals with relations between regional organizations and the UN Security Council under Chapter VIII of the UN Charter. In this respect, the most recent trends are a shift from subsidiarity to a more equal partnership between these two subjects. The two models of action by delegation or authorization of the Security Council are in fact autonomous. This is demonstrated by the preparatory works of the UN Charter and subsequent practice. The model of authorized regional action enriches the range of instruments that the United Nations Charter provides for the maintenance of peace and collective security.