Search results for "HDM"

showing 10 items of 140 documents

Fasciola spp: Mapping of the MF6 epitope and antigenic analysis of the MF6p/HDM family of heme-binding proteins

2017

MF6p/FhHDM-1 is a small cationic heme-binding protein which is recognized by the monoclonal antibody (mAb) MF6, and abundantly present in parenchymal cells and secreted antigens of Fasciola hepatica. Orthologs of this protein (MF6p/HDMs) also exist in other causal agents of important foodborne trematodiasis, such as Clonorchis sinensis, Opisthorchis viverrini and Paragonimus westermani. Considering that MF6p/FhHDM-1 is relevant for heme homeostasis in Fasciola and was reported to have immunomodulatory properties, this protein is expected to be a useful target for vaccination. Thus, in this study we mapped the epitope recognized by mAb MF6 and evaluated its antigenicity in sheep. The sequenc…

0301 basic medicineParagonimus westermaniFasciola sppPhysiologyProtein ConformationFlatwormslcsh:MedicineProtein Structure PredictionBiochemistryEpitopeAntigenicEpitopes0302 clinical medicineAnimal CellsImmune PhysiologyMedicine and Health SciencesMacromolecular Structure AnalysisMF6p/HDMEnzyme-Linked Immunoassayslcsh:ScienceMammalsNeuronsImmune System ProteinsMultidisciplinaryFasciolabiologyVaccinationEukaryotaAntibodies MonoclonalRuminantsDendritic StructureVertebratesCellular TypesAntibodyResearch ArticleHemeproteinsProtein StructureAntigenicityFascioliasisHeme bindingImmunology030231 tropical medicineAntibodies HelminthEnzyme-Linked Immunosorbent AssayHemeResearch and Analysis MethodsTrematodesAntibodiesHeme-Binding Proteins03 medical and health sciencesHelminthsparasitic diseasesParasitic DiseasesFasciola hepaticaAnimalsImmunoassaysMolecular BiologySheeplcsh:ROrganismsBiology and Life SciencesProteinsCell BiologyDendritesNeuronal DendritesFasciola hepaticabiology.organism_classificationInvertebratesMolecular biologyFasciola030104 developmental biologyEpitope mappingCellular NeuroscienceAntigens HelminthAmniotesImmunologic Techniquesbiology.proteinlcsh:QCarrier ProteinsEpitope MappingNeuroscience
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Nasal IgE in subjects with allergic and non-allergic rhinitis

2020

Abstract Purpose The prevalence of "ocal allergic rhinitis" within individuals suffering from perennial rhinitis remains uncertain, and patients usually are diagnosed with non-allergic rhinitis. The aim of this study was to evaluate the prevalence of a potential "local allergic rhinitis" in subjects suffering from non-allergic rhinitis in a non-selected group of young students. Methods 131 students (age 25.0 ± 5.1 years) with a possible allergic rhinitis and 25 non-allergic controls without rhinitis symptoms (age 22.0 ± 2.0 years) were recruited by public postings. 97 of 131 students with rhinitis were tested positive (≥3 mm) to prick testing with 17 frequent allergens at visit 1. Twenty-fo…

AllergyNon-allergic rhinitismedicine.medical_treatmentImmunoglobulin EAR + HDM allergic rhinitis with house dust mite allergyAllergic rhinitisHDM house dust miteNPT nasal provocation testsAR allergic rhinitis0302 clinical medicineISAAC International Study of Asthma and Allergies in Childhood questionnaireNARES non-allergic rhinitis with eosinophilia-syndromeMedicine and Health SciencesImmunology and Allergy030223 otorhinolaryngologyeducation.field_of_studybiologymedicine.diagnostic_testRadioallergosorbent testsIgE allergen-specific IgENon-allergicD1 Dermatophagoides pteronyssinusPREVALENCED2 Dermatophagoides farinaeLAR local allergic rhinitisPROVOCATION TESTSPulmonary and Respiratory Medicinelcsh:Immunologic diseases. AllergyLOCAL IGEImmunologyPopulationPATHOPHYSIOLOGYNon-allergic-rhinitisLocal allergic rhinitisGCP Good Clinical PracticeDIAGNOSISNasal provocation testArticleSECRETIONS03 medical and health sciencesFEV1/FVC ratiorhinitismedicineddc:610educationHouse dust mitebusiness.industryFEV1 forced expiratory volume in one secondRAST Radioallergosorbent Testbiology.organism_classificationmedicine.disease030228 respiratory systemHouse dust mite allergyPNIF peak nasal inspiratory flowImmunologyFVC forced vital capacitybiology.proteinbusinessSD standard deviationlcsh:RC581-607Local IgESPT skin prick testWorld Allergy Organization Journal
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"Table 28: Mass distribution, 3 tag, mbb window 170" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in th…

2018

The mass distribution of the llbb system used in the fit to derive the limits for the mbb window centered at 170 GeV for the nb >= 3 (3 tag) category.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionmass distributionb-associated productionMHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 73: Mass distribution, 2 tag, mbb window 420" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in th…

2018

The mass distribution of the llbb system used in the fit to derive the limits for the mbb window centered at 420 GeV for the nb = 2 (2 tag) category.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionmass distributionb-associated productionMHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 6: Cross-section limits type-I tanb 10" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in the $\el…

2018

The cross section times BR(A->ZH) times BR(H->bb) limits for an A boson in the type-I, tanbeta 10, 2HDM. For each signal point, characterised by the mass pair (mA, mH), two limits are provided, the observed and the expected. The correct width as predicted by this particular parameter choice of the 2HDM is used. For type-I only gluon-gluon fusion is used and the nb=2 category only.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionCLScross section limitsHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 47: Mass distribution, 2 tag, mbb window 280" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in th…

2018

The mass distribution of the llbb system used in the fit to derive the limits for the mbb window centered at 280 GeV for the nb = 2 (2 tag) category.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionmass distributionb-associated productionMHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 43: Mass distribution, 2 tag, mbb window 260" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in th…

2018

The mass distribution of the llbb system used in the fit to derive the limits for the mbb window centered at 260 GeV for the nb = 2 (2 tag) category.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionmass distributionb-associated productionMHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 125: Mass distribution, 2 tag, mbb window 690" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in t…

2018

The mass distribution of the llbb system used in the fit to derive the limits for the mbb window centered at 690 GeV for the nb = 2 (2 tag) category.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionmass distributionb-associated productionMHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 87: Mass distribution, 2 tag, mbb window 490" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in th…

2018

The mass distribution of the llbb system used in the fit to derive the limits for the mbb window centered at 490 GeV for the nb = 2 (2 tag) category.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionmass distributionb-associated productionMHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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"Table 102: Mass distribution, 3 tag, mbb window 570" of "Search for a heavy Higgs boson decaying into a $Z$ boson and another heavy Higgs boson in t…

2018

The mass distribution of the llbb system used in the fit to derive the limits for the mbb window centered at 570 GeV for the nb >= 3 (3 tag) category.

Z0 --> MU+ MU-Z0 --> E+ E-2HDMP P --> HIGGSHIGGS --> BQ BQBAR13000.0gluon-gluon fusionmass distributionb-associated productionMHiggs boson productionHIGGS --> Z0 HIGGSgluon fusion
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