Search results for "HERA"
showing 10 items of 14928 documents
Implementation of Substitution Treatment in Finland: Beyond Rationalisation and Medicalisation
2011
AIMS Finnish treatment of drug abuse has during the last two decades shifted from a predominantly psychosocial approach to a more medical mode. This is especially evident in the rapid implementation of substitution treatments (STs). My aim is to show that labelling this development as ‘medicalisation’ or ‘rationalisation’ as a form of medical progress will not increase our understanding of the change. MATERIAL AND DESIGN I analysed texts from several periodicals with psychosocial, social policy and medical perspectives between 1997 and 2005. Four basic conceptual and argumentative underpinnings emerged which gave credence to the medical and rationalapproach, and the validity of these four e…
Antioxidant Therapies and Oxidative Stress in Friedreich´s Ataxia: The Right Path or Just a Diversion?
2020
Friedreich's ataxia is the commonest autosomal recessive ataxia among population of European descent. Despite the huge advances performed in the last decades, a cure still remains elusive. One of the most studied hallmarks of the disease is the increased production of oxidative stress markers in patients and models. This feature has been the motivation to develop treatments that aim to counteract such boost of free radicals and to enhance the production of antioxidant defenses. In this work, we present and critically review those 'antioxidant' drugs that went beyond the disease's models and were approved for its application in clinical trials. The evaluation of these trials highlights some …
Global Real-World Evidence of Sofosbuvir/Velpatasvir as a Highly Effective Treatment and Elimination Tool in People with Hepatitis C Infection Experi…
2022
HCV elimination; Mental health disorders; Sofosbuvir/velpatasvir Eliminación del VHC; Trastornos de salud mental; Sofosbuvir/velpatasvir Eliminació del VHC; Trastorns de salut mental; Sofosbuvir/velpatasvir Hepatitis C virus (HCV) is prevalent in people with mental health disorders, a priority population to diagnose and cure in order to achieve HCV elimination. This integrated analysis pooled data from 20 cohorts in seven countries to evaluate the real-world effectiveness of the pangenotypic direct-acting antiviral (DAA) sofosbuvir/velpatasvir (SOF/VEL) in people with mental health disorders. HCV-infected patients diagnosed with mental health disorders who were treated with SOF/VEL for 12 w…
Acute and chronic effects of cold treatment on physiological variables and neuromuscular function during a short training period in men
2015
Introduction. Recovery following various physical exercises is a complicated process. The exercise session can involve strong demands on both muscle structure and energy production (aerobic and anaerobic). Many exercise sessions also induce muscle damage (exercise induced muscle damage; EIMD). Different recovery methods attempt to alleviate or prevent EIMD and its associated symptoms, such as muscle soreness and swelling, and reduction in muscle function. One of the used strategies is cold treatment (cryotherapy), which decreases tissue temperature and subsequently effects on e.g. blood flow, metabolism and neural conductance velocity. To date, there is conflicting evidence to support the u…
Water immersion methods do not alter muscle damage and inflammation biomarkers after high-intensity sprinting and jumping exercise
2020
Purpose The aim of this study was to compare the efficacy of three water immersion interventions performed after active recovery compared to active recovery only on the resolution of inflammation and markers of muscle damage post-exercise. Methods Nine physically active men (n = 9; age 20‒35 years) performed an intensive loading protocol, including maximal jumps and sprinting on four occasions. After each trial, one of three recovery interventions (10 min duration) was used in a random order: cold-water immersion (CWI, 10 °C), thermoneutral water immersion (TWI, 24 °C), contrast water therapy (CWT, alternately 10 °C and 38 °C). All of these methods were performed after an active recovery (1…
Sobre la identidad y procedencia del poeta Filóxeno y la autoría del ditirambo ???????
2019
El presente estudio pretende resolver la controversia en torno a la identidad y procedencia del poeta Filóxeno, célebre ditirambógrafo del siglo V-IV a.C. Para ello, hemos recopilado todos los testimonios que citan a personajes con el nombre de Filóxeno desde la primera mención de Aristófanes. La investigación ha revelado que existen varios individuos con el mismo nombre y rasgos comunes. No obstante, el examen de estos testimonios revela la existencia de un único autor de ditirambos: Filóxeno de Citera. Además, creemos que este poeta fue el autor del ditirambo ???????, que algunos editores atribuyeron falsamente a Filóxeno de Léucade. Posteriormente, reflexionamos sobre la identidad de Fil…
Conceptions of healthcare professionals about rehabilitees’ participation in goal setting in an acute hospital : a phenomenographic study
2022
Purpose: In acute care, effective goal-setting is an essential phase of a successful rehabilitation process. However, professionals’ knowledge and skills in rehabilitee-centered practice may not always match the ways of implementing goal-setting. This study aimed to describe the variation in how acute hospital professionals perceive and comprehend rehabilitee participation in rehabilitation goal-setting. Methods: Data were collected by interviewing 27 multidisciplinary rehabilitation team members in small groups shortly after rehabilitation goal-setting sessions. A qualitative research design based on phenomenography was implemented. Results: We identified four conceptions of rehabilitee pa…
Accelerometer-based physical activity in need satisfaction profiles of schoolchildren: A 3-year follow-up
2023
This study examined moderate-to-vigorous physical activity (MVPA) trends in physical education (PE) classes and beyond school hours in children's need satisfaction profiles over 3 years. Participants were 445 (girls 256, boys 189) Finnish schoolchildren ( Mage = 11.26 ± 0.32 years). Need satisfaction self-reports and accelerometer-based MVPA data were collected in 17 comprehensive schools over four assessment phases. Four latent profiles based on the need satisfaction trends over time were found: Profiles with Large Decrease, Small Decrease, Small Increase, and Large Increase. The children with the most prominent need satisfaction decreases showed a significant decline in out-of-school MVP…
Efficacy of “Family Connections”, a program for relatives of people with borderline personality disorder, in the Spanish population: study protocol f…
2020
Abstract Background Patients with borderline personality disorder (BPD) experience significant affect regulation difficulties that cause serious consequences in their work, emotional, and social environments. This dysfunctional pattern also produces great suffering and a heavy burden on their relatives. Fortunately, some studies show that treatment of relatives of people with BPD begins to be important in the patients’ recovery and in improving family dynamics. One of the treatments that has obtained the most empirical support is Family connections (FC). This 12-session program is an adaptation of different Dialectical Behavior Therapy strategies. To test the efficacy of FC, five uncontroll…
Effectiveness of family connections intervention for family members of persons with personality disorders in two different formats: Online vs face-to…
2022
Introduction: Personality disorders (PD) have a serious impact on the lives of individuals who suffer from them and those around them. It is common for family members to experience high levels of burden, anxiety, and depression, and deterioration in their quality of life. It is curious that few interventions have been developed for family members of people with PD. However, Family Connections (FC) (Hoffman and Fruzzetti, 2005) is the most empirically supported intervention for family members of people with Borderline Personality Disorder (BPD). Aim: The aim of this study is to explore the effectiveness of online vs face-to-face FC. Given the current social constraints resulting from SARS-Co…