Search results for "HERO"
showing 10 items of 1331 documents
Updated diagnosticprognostic paradigm for CAD: a narrative review.
2020
Cardiovascular diseases are the first cause of death globally; early detection of coronary artery disease (CAD) is a challenge for clinicians and radiologists. Over the past 2 decades there have been several improvements in the methods for the assessment of diagnosis and prognosis in patients with suspected CAD; most of these methods are imaging methods and they operate with high-end technologies. Cardiac computed tomography (CCT) as we know it today was introduced in 1998 and has ever progressed with constant pace. The first decade was the technical validation phase of the method while the second decade was the clinical validation phase. CCT has developed an excellent diagnostic and progno…
Pheromones linked to sexual behaviors excite the appetitive phase of feeding behavior of Aplysia fasciata . I. Modulation and excitation of appetitiv…
1998
Pheromones presumably secreted by mating conspecifics – as well as homogenates containing tissue that is homologous with the atrial gland – increase the time that Aplysia fasciata spend feeding. This effect is caused by increasing the number of feeding episodes initiated in response to food, whereas the duration of a feeding bout remains unchanged. The increase in the number of feeding episodes is related to increases in head waving and crawling, i.e., appetitive movements that bring the animal into contact with food, as well as an increase in the responsiveness to food after it is contacted. Releasing a homogenate containing atrial gland tissue, or egg laying hormone, in the water near the…
Pheromones linked to sexual behaviors excite the appetitive phase of feeding behavior of Aplysia fasciata II. Excitation of C-PR, a neuron involved i…
1998
Pheromones presumably released by conspecifics amplify both the appetitive and the consummatory components of feeding in Aplysia. These effects can be mimicked by administering homogenate of the large hermaphroditic duct containing atrial gland tissue, as well as peptides from the bag cells. Identified cerebro-pedal regulator (C-PR) neuron is thought to command various behaviors that comprise the appetitive phase of feeding. In a reduced preparation, we investigated the effects on the C-PR of applying these substances to the rhinophores, the sensory organs which detect pheromones. Stimuli that excite feeding in the animal were also found to affect the C-PR. Large hermaphroditic duct homogen…
Evaluation of C-Reactive Protein in Primary and Secondary Prevention
2007
Inflammation is pivotal in atherosclerosis, and C-reactive protein (CRP) is an inflammatory marker that predicts cardiovascular events. Several population-based studies have demonstrated that baseline CRP levels predict future cardiovascular events. CRP testing may thus have a major adjunctive role in the global assessment of cardiovascular risk. Recently, the National Cholesterol Education Program, through the Adult Treatment Panel III guidelines, identified CRP and another marker of inflammation, the fibrinogen, as “emerging risk factors,” suggesting that their measurement may improve the estimations of absolute risk obtained using the traditional cardiovascular risk factors. In terms of…
Pathophysiological and clinical aspects of malnutrition in chronic renal failure
2005
AbstractKidney diseases are the ninth leading cause of death in the USA. In these patients cardiovascular mortality is greater than in the general population. This observation, not completely explained by the so-called ‘traditional’ cardiovascular risk factors, lead the authors to postulate other ‘emerging’ ones found in chronic renal failure patients. Among these new findings, nutritional status, considered as the balance existing between nutrient requirements and intakes, plays an important role for the development of cardiovascular diseases. In fact several nutritional parameters are widely known as pathophysiological determinants of cardiovascular disturbances, which are based on accele…
Cardiovascular Imaging Techniques in Systemic Rheumatic Diseases
2018
The risk of cardiovascular (CV) events and mortality is significantly higher in patients with systemic rheumatic diseases than in the general population. Although CV involvement in such patients is highly heterogeneous and may affect various structures of the heart, it can now be diagnosed earlier and promptly treated. Various types of assessments are employed for the evaluation of CV risk such as transthoracic or transesophageal echocardiography, magnetic resonance imaging (MRI), and computed tomography (CT) to investigate valve abnormalities, pericardial disease, and ventricular wall motion defects. The diameter of coronary arteries can be assessed using invasive quantitative coronarograp…
Prognostic value of cardiac CT
2020
In the past decades, coronary computed tomography angiography (CCTA) has become a powerful tool in the management of coronary artery disease. The diagnostic and prognostic value of CCTA has been extensively demonstrated in both large observational studies and clinical trials among stable chest pain patients. The quantification of coronary artery calcium score (CACS) is a well-established predictor of cardiovascular morbidity and mortality in asymptomatic subjects. Besides CACS, the main strength of CCTA is the accurate assessment of the individual total atherosclerotic plaque burden, which holds important prognostic information. In addition, CCTA, by providing detailed information on corona…
A rare case of ruptured aneurysm of the paramedian artery of Percheron.
2018
Introduction The artery of Percheron is a rare anatomic variant supplying bilateral medial thalamic nuclei and a variable portion of the rostral part of midbrain. Case report A 48-year-old female with massive subarachnoid hemorrhage due to a ruptured aneurysm of the paramedian artery of Percheron presented to the emergency room. Because of significant risk of recurrent intracranial hemorrhage, it was decided to proceed with endovascular embolization of the aneurysm. The patient was ultimately sent to a rehabilitation center and her presenting neurologic deficits showed significant improvements in the weeks following endovascular embolization treatment. Discussion The paramedian artery of Pe…
Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement
2020
Genome sequencing and gene-based therapies appear poised to advance the management of rare lipoprotein disorders and associated dyslipidaemias. However, in practice, underdiagnosis and undertreatment of these disorders are common, in large part due to interindividual variability in the genetic causes and phenotypic presentation of these conditions. To address these challenges, the European Atherosclerosis Society formed a task force to provide practical clinical guidance focusing on patients with extreme concentrations (either low or high) of plasma low-density lipoprotein cholesterol, triglycerides, or high-density lipoprotein cholesterol. The task force also recognises the scarcity of qua…