Search results for "HIF"
showing 10 items of 1515 documents
Different sensory aspects of a food are not remembered with equal acuity
2009
International audience; In the present study, food memory for three sensory aspects involved in food perception, taste, texture and aroma, is compared. Participants received a lunch including a custard dessert (target) under incidental learning condition. One day later, participants were presented with samples identical to the target and with distractors varying either in sweetness, thickness or cherry aroma. Memory was assessed by an absolute recognition question (“Did you eat this sample yesterday?”) and by relative questions (“Is this sample less, equal or more sweet than the sample you ate yesterday?”). Results showed better memory performance for sweetness than for the two other sensor…
Obruchevacanthus ireneae gen. et sp. nov., a new ischnacanthiform (Acanthodii) from the Lower Devonian of Spain
2014
New disarticulated material of typically ischnacanthid scales, tooth whorls, and ?dentigerous jaw bones that occur recurrently together at many levels of the Lower Devonian of the Iberian Chain (Spain) is described. Based on their stratigraphical occurrence, histological evidence and comparison with similar ischnacanthid assemblages from other localities, we suggest including all of these remains in a unique natural assemblage, Obruchevacanthus ireneae gen. et sp. nov. This new taxon shares some features with Trundlelepis cervicostulata from the Lower Devonian of New South Wales (Australia), as for example the presence of a poorly developed pore canal system in their scales. This feature su…
Improved time-resolved acousto-optic technique for optical fiber analysis of axial non-uniformities by using edge interrogation
2015
The time-resolved acousto-optic technique demonstrated recently to be a very useful method for the analysis of fiber axial non-uniformities, able to detect variations of fiber diameter in the nanometric scale with a spatial resolution of few cm. An edge interrogation approach is proposed to improve further the performance of this technique. The detection of subnanometer fiber diameter changes or sub-ppm changes of the core refractive index is demonstrated.
High-precision mass measurement of $^{168}$Yb for verification of nonlinear isotope shift
2020
The absolute mass value of $^{168}$Yb has been directly determined with the JYFLTRAP Penning trap mass spectrometer at the Ion Guide Isotope Separator On-Line (IGISOL) facility. A more precise value of the mass of $^{168}$Yb is needed to extract possible signatures of beyond standard model physics from high-precision isotope shift measurements of Yb atomic transition frequencies. The measured mass-excess value, ME($^{168}$Yb) = $-$61579.846(94) keV, is 12 times more precise and deviates from the Atomic Mass Evaluation 2016 value by 1.7$\sigma$. The impact on precision isotope shift studies of the stable Yb isotopes is discussed.
NiII, and ZnII Schiff Base Complexes: Telomeric G-quadruplex Stabilizers
2014
Recently, NiII and ZnII metal complexes of the ligand Salpyrim have been synthesized and characterized. Their affinity for wild-type h-Telo G-quadruplex DNA and for calf thymus DNA was investigated by UV absorption spectroscopy, circular dichroism and viscometry. The data collectively suggest that both complexes bind effectively to G-quadruplexes by direct end-stacking, stabilizing the oligonucleotide secondary structure. The two complexes are also typical B-DNA intercalators. Remarkably, their binding constants, Kb, with the G4s structures are about 10 fold higher than those with B-DNA, highlighting the selectivity. Experiments to evaluate the biological activity of the two complexes again…
The cognitive shift in terminology and specialized translation
2009
Este artículo propone un análisis crítico y una visión global de las teorías terminológicas con especial atención a la traducción científica y técnica. El estudio de los tecnolectos está sometido en la actualidad a un cambio hacia el cognitivismo, que a su vez conduce a un énfasis mucho mayor tanto en el significado como en las estructuras conceptuales que subyacen en los textos y en la lengua en general. La terminología parece estar pasando del prescriptivismo al descriptivismo, con un interés creciente por enfocar el estudio de las unidades de los tecnolectos desde una perspectiva social, lingüística y cognitiva. En esta misma línea, comienzan a oírse nuevas voces que ofrecen perspectivas…
The effect of some amines and alcohols on the organized structure of [bmim][BF4] investigated by 1H NMR spectroscopy
2008
The effect exerted by some amines and alcohols on the 1H NMR spectra of 1-butyl-3- methylimidazolium tetrafluoroborate [bmim][BF4] has been studied. This ionic liquid, which is one of the most widely used, is characterized by a high structural order degree, as a consequence of the symmetry and the coordination ability of the anion. In order to have information about the dependence of the detected effects on the alcohol or amine structure, some different primary, secondary and tertiary amines and alcohols have been considered. Furthermore, in the case of amines, their basicity has been also taken into account. Both amines and alcohols induce variation in chemical shifts values and signal mul…
A Language Shift Simulation Based on Cellular Automata
2011
Language extinction is a widespread social phenomenon affecting several million people throughout the world today. By the end of this century, more than 5100 of the approximately 6000 languages currently spoken around the world will have disappeared. This is mainly because of language shifts, i.e., because a community of speakers stops using their traditional language and speaks a new one in all communication settings. In this study, the authors present the properties of a cellular automaton that incorporates some assumptions from the Gaelic-Arvanitika model of language shifts and the findings on the dynamics of social impacts in the field of social psychology. To assess the cellular automa…
Solvent Modulated Assembly of Two Ni(II) Complexes: Syntheses, Structures and Magnetic Properties
2016
A dinuclear [Ni2(L)2(DMSO)2(MeOH)2] (1) and a tetra-nuclear [Ni4(L)4(DMF)2(H2O)2].DMF (2) Ni(II) complexes have been prepared by treating nickel nitrate hexahydrate with the Schiff base ligand H2L (H2L=(E)-2-(2-hydroxybenzyliden)amino-4-nitrophenol) in a one-pot reaction. Complex 1 was obtained after recrystallization of the precipitate from the reaction with a 1:1:1 mixture of DMSO/CH2Cl2/MeOH. In contrast, the tetrameric complex 2 was obtained after slow evaporation of the filtrate. Both complexes were characterized by analytical, thermogravimetric, optical and magnetic techniques. The solid state molecular structures of 1 and 2 were determined by single crystal X-ray crystallography. Com…
Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1α
2007
We reported previously that the obesity hormone leptin is overexpressed in breast cancer biopsies. Here, we investigated molecular mechanisms involved in this process, focusing on conditions that are associated with obesity, that is, hyperinsulinemia and induction of hypoxia. By using quantitative real-time PCR, immunofluorescent detection of proteins and enzyme-linked immunosorbent assays, we found that treatment of MCF-7 breast cancer cells with high doses of insulin or the hypoxia-mimetic agent CoCl2, or culturing the cells under hypoxic conditions significantly increased the expression of leptin mRNA and protein. Notably, the greatest leptin mRNA and protein expression were observed und…