Search results for "HM"

[Spanish asthma patients' beliefs about health and medicines: validation of 2 questionnaires].

2008

Abstract Objective We translated 2 health beliefs questionnaires–an instrument based on the health belief model (HBM) containing 19 items in 6 domains and the Beliefs About Medicines Questionnaire (BMQ) containing 18 items divided into a general and a specific section–and then administered and validated them in a group of Spanish patients with asthma. Patients and Methods In 2 clinical visits data were collected on 126 patients with stable asthma of different levels of severity. At the first visit, the patients underwent spirometry and were asked questions about sociodemographic factors and clinical history. At the second visit, they completed the State-Trait Anxiety Inventory, the Beck Dep…

Measuring Task-Switching Ability in the Implicit Association Test

2005

Abstract. Recently, the role of method-specific variance in the Implicit Association Test (IAT) was examined ( McFarland & Crouch, 2002 ; Mierke & Klauer, 2003 ). This article presents a new content-unspecific control task for the assessment of task-switching ability within the IAT methodology. Study 1 showed that this task exhibited good internal consistency and stability. Studies 2-4 examined method-specific variance in the IAT and showed that the control task is significantly associated with conventionally scored IAT effects of the IAT-Anxiety. Using the D measures proposed by Greenwald, Nosek, and Banaji (2003 ), the amount of method-specific variance in the IAT-Anxiety could b…

Lorcainide; II. Plasma concentration-effect relationship

1979

Quantifying changes in EEG complexity induced by photic stimulation.

2009

Summary Objectives: This study aims to characterize EEG complexity, measured as the prediction error resulting from nonlinear prediction, in healthy humans during photic stimulation. Methods: EEGs were recorded from 15 subjects with eyes closed (EC) and eyes open (EO), during the baseline condition and during stroboscopic photic stimulation (PS) at 5, 10, and 15 Hz. The mean squared prediction error (MSPE) resulting from nearest neighbor local linear prediction was taken as complexity index. Complexity maps were generated interpolating the MSPE index over a schematic scalp representation. Results: Statistical analysis revealed that: i) EEG shows good predictability in all conditions and see…

Non‐uniform displacement within ruptured Achilles tendon during isometric contraction

2021

The purpose of this study was investigate tendon displacement patterns in non-surgically treated patients 14 months after acute Achilles tendon rupture (ATR) and to classify patients into groups based on their Achilles tendon (AT) displacement patterns. Twenty patients were tested. Sagittal images of AT were acquired using B-mode ultrasonography during ramp contractions at a torque level corresponding to 30% of the maximal isometric plantarflexion torque of the uninjured limb. A speckle tracking algorithm was used to track proximal-distal movement of the tendon tissue at 6 antero-posterior locations. Two-way repeated measures ANOVA for peak tendon displacement was performed. K-means cluster…

Human walking along a curved path. II. Gait features and EMG patterns

2003

We recorded basic gait features and associated patterns of leg muscle activity, occurring during continuous body progression when humans walked along a curved trajectory, in order to gain insight into the nervous mechanisms underlying the control of the asymmetric movements of the two legs. The same rhythm was propagated to both legs, in spite of inner and outer strides diverging in length (P < 0.001). There was a phase lag in limb displacement between the inner and outer leg of 7% of the total cycle duration (P = 0.0001). Swing velocity was greater for outer than inner foot (P < 0.001). The duration of the stance phase diminished and increased in the outer and inner leg (P < 0.01), respect…

Potent bronchoprotective effect of deep inspiration and its absence in asthma

2000

In the absence of deep inspirations, healthy individuals develop bronchoconstriction with methacholine inhalation. One hypothesis is that deep inspiration results in bronchodilation. In this study, we tested an alternative hypothesis, that deep inspiration acts as a bronchoprotector. Single-dose methacholine bronchoprovocations were performed after 20 min of deep breath inhibition, in nine healthy subjects and in eight asthmatics, to establish the dose that reduces forced expiratory volume in 1 s by &gt;15%. The provocation was repeated with two and five deep inspirations preceding methacholine. Additional studies were carried out to assess optimization and reproducibility of the protocol …

Individuality of movements in music--finger and body movements during playing of the flute.

2013

The achievement of mastery in playing a composition by means of a musical instrument typically requires numerous repetitions and corrections according to the keys and notations of the music piece. Nevertheless, differences in the interpretation of the same music piece by highly skilled musicians seem to be recognizable. The present study investigated differences within and between skilled flute players in their finger and body movements playing the same piece several times on the same and on different days. Six semiprofessional and four professional musicians played an excerpt of Mozart’s Flute Concerto No. 2 several times on three different days. Finger and body movements were recorded by …

Whole-exome sequencing identifies the first French MODY 6 family with a new mutation in the NEUROD1 gene

2020

Abstract Aim The aim of the present study was to identify the affected gene in a French family with maturity-onset diabetes of the young (MODY) using whole-exome sequencing (WES). Methods WES was performed in one patient with MODY, and candidate variants were confirmed in members of the immediate family by Sanger sequencing. Results In the proband, a new heterozygous missense mutation (c.340A>C) was identified in the NEUROD1 gene by WES analysis and confirmed by Sanger sequencing. Additional Sanger sequencing of the proband's sister and mother revealed the same heterozygous mutation. The proband and his sister displayed typical clinical characteristics of MODY, while their mother had the sa…

Autosomal recessive hypercholesterolemia in a Sicilian kindred harboring the 432insA mutation of the ARH gene

2003

Abstract We describe a Sicilian family presenting a recessive form of hypercholesterolemia harboring a mutation of the autosomal recessive hypercholesterolemia (ARH) gene. In two of the three sibs, a 26-year-old male and a 22-year-old female, a severe hypercholesterolemia was diagnosed with very high levels of plasma cholesterol (15.9 and 12.2 mmol/l, respectively); tendon xanthomatas and xanthelasms were present and in the male proband was documented a diffuse coronary atherosclerotic disease with a rapid and fatal progression. Both the parents had normal or slightly increased levels of plasma cholesterol. All causes of secondary hypercholesterolemia were ruled out as well as an involvemen…