Search results for "HMI"
showing 10 items of 931 documents
Training session intensity affects plasma redox status in amateur rhythmic gymnasts
2016
Purpose: The aim of this study was to examine systemic responses of oxidant/antioxidant status following 2 training sessions of different intensity in amateur rhythmic gymnasts. Methods: Before the experimental training, 10 female gymnasts performed a gradually increased exercise test to assess maximal heart rate, maximal oxygen consumption, and anaerobic threshold. They executed 2 intermittent training sessions separated by 48 h of recovery (48 h-post R): the first was performed at low-moderate intensity (LMI) and the second at high intensity (HI). Blood samples were collected immediately pre- and post-training and 48 h-post R. Hydroperoxide level (OxL) and total antioxidant capacity (TAC)…
Chronically elevated branched chain amino acid levels are pro-arrhythmic.
2022
Aim. Cardiac arrhythmias comprise a major health and economic burden and are associated with significant morbidity and mortality, including cardiac failure, stroke and sudden cardiac death (SCD). Development of efficient preventive and therapeutic strategies is hampered by incomplete knowledge of disease mechanisms and pathways. Our aim is to identify novel mechanisms underlying cardiac arrhythmia and SCD using an unbiased approach. Methods and Results. We employed a phenotype-driven N-ethyl-N-nitrosourea (ENU) mutagenesis screen and identified a mouse line with a high incidence of sudden death at young age (6-9 weeks) in the absence of prior symptoms. Affected mice were found to be homozyg…
The TRPA1 Channel in the Cardiovascular System: Promising Features and Challenges.
2019
The transient receptor potential ankyrin 1 (TRPA1) channel is a calcium-permeable nonselective cation channel in the plasma membrane that belongs to the transient receptor potential (TRP) channel superfamily. Recent studies have suggested that the TRPA1 channel plays an essential role in the development and progression of several cardiovascular conditions, such as atherosclerosis, heart failure, myocardial ischemia–reperfusion injury, myocardial fibrosis, arrhythmia, vasodilation, and hypertension. Activation of the TRPA1 channel has a protective effect against the development of atherosclerosis. Furthermore, TRPA1 channel activation elicits peripheral vasodilation and induces a biphasic bl…
Autonomic Modulation Improves in Response to Harder Performances While Playing Wind Instruments
2020
Background: Despite inducing autonomic benefits similar to exercise, playing wind instruments is a physical, and cognitive task of high attentional requirements, which demands musicians maximal efforts, leading to sympathetic hyperarousal and autonomic worsening. In this context of controversy, it remains unknown the autonomic response to playing highly demanding music performances, as compared to an easier one, which might be of interest in wind musicians' cardiovascular health. Objectives: This study aimed to investigate differences in the autonomic control of the heart with regard to task demands (TD), avoiding emotional influences (rehearsal performance). Methods: Eight healthy male pro…
Sourcing on the internet: Examining the relations among different phases of online inquiry
2021
This study examined students’ engagement in sourcing throughout online inquiry, that is, when they specified the information need, formulated search queries, evaluated online texts, and composed a written product. Participants were 167 upper secondary school students. Students completed an online inquiry task in a restricted online environment that utilized authentic online texts. Students’ prior topic knowledge and reading fluency was measured and controlled for in the analysis. The results showed that students engaged in sourcing even in the earliest phases of online inquiry. A sequential regression analysis indicated that the more frequently students engaged in sourcing in specifying the…
Factors affecting basket catheter detection of real and phantom rotors in the atria: A computational study
2018
[EN] Anatomically based procedures to ablate atrial fibrillation (AF) are often successful in terminating paroxysmal AF. However, the ability to terminate persistent AF remains disappointing. New mechanistic approaches use multiple-electrode basket catheter mapping to localize and target AF drivers in the form of rotors but significant concerns remain about their accuracy. We aimed to evaluate how electrode-endocardium distance, far-field sources and inter-electrode distance affect the accuracy of localizing rotors. Sustained rotor activation of the atria was simulated numerically and mapped using a virtual basket catheter with varying electrode densities placed at different positions withi…
Impact of monitoring on detection of arrhythmia recurrences in the ESC-EHRA EORP atrial fibrillation ablation long-term registry
2019
Abstract Aims Monitoring of patients after ablation had wide variations in the ESC-EHRA atrial fibrillation ablation long-term (AFA-LT) registry. We aimed to compare four different monitoring strategies after catheter AF ablation. Methods and results The ESC-EHRA AFA-LT registry included 3593 patients who underwent ablation. Arrhythmia monitoring during follow-up was performed by 12-lead electrocardiogram (ECG), Holter ECG, trans-telephonic ECG monitoring (TTMON), or an implanted cardiac monitoring (ICM) system. Patients were selected to a given monitoring group according to the most extensive ECG tool used in each of them. Comparison of the probability of freedom from recurrences was perfo…
DISTRIBUTION OF CARBON STARS IN THE GALAXY
2018
A search for new faint carbon (C) stars in the Polar region δ > 55o has been accomplished by obtaining objective prism spectra in the near infrared 550 -- 900 nm on images of CCD camera of Baldone Schmidt telescope of Astrophysical observatory. The positions of stars having color indices (J – K) > 1.3 mag in Two Micron All Sky Infrared Survey (2MASS) were selected to pick out suspicious carbon stars.Our survey is limited in brightness by J < 10 mag. 24 new carbon stars were found and their characteristics obtained. The correlative relation between Teff and spectral gradient [757 – 685] was confirmed. Such characteristics as Teff, distance from the Sun, absolute Mk were obtained…
Thermal stability of transition alumina nanocrystals with different microstructures
2018
Abstract The preparation of well-crystallized boehmite nanoparticles with different morphologies, encompassing from aciculae or rods of 320, 150 and 70 nm of length to platelets of 50 nm in diameter, allowed a comparative study of their respective thermal evolutions as alumina precursors. Static thermal treatments of boehmite nanocrystals at 600, 1000 and 1200 °C and a dynamic, in situ synchrotron study between 100 and 1000 °C revealed that original boehmite microstructures, i.e. size and shape of the nanoparticles, were kept not only in γ-Al 2 O 3 but also in transitional aluminas up to 1000 °C. Specifically, at that temperature, acicular samples presented θ-Al 2 O 3 structure, while in pl…
André Aciman: Etsi minut
2020
Kirja-arvostelu teoksesta André Aciman: Etsi minut (Find me). Suom. Antero Tiittula. Tammi 2020. 294 s. nonPeerReviewed