Search results for "HOSPITALIZATION"

showing 10 items of 463 documents

Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19

2023

Abstract Background We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admiss…

MaleEpidemiologyMESH: HospitalizationMESH: Proportional Hazards ModelsMESH: Risk FactorsRisk FactorsMESH: Childcohort studyMESH: COVID-19HumansMESH: SARS-CoV-2ChildProportional Hazards ModelsMESH: HumansMESH: Middle AgedSARS-CoV-2COVID-19risk of deathGeneral MedicineMiddle AgedCOVID-19; SARS-CoV-2; co-morbidities; cohort study; risk of death; symptoms; treatmentsMESH: MaleHospitalizationIntensive Care Unitsco-morbiditiestreatmentssymptomsMESH: Intensive Care Units[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieCOVID-19/therapy
researchProduct

The palliative-supportive care unit in a comprehensive cancer center as crossroad for patients' oncological pathway

2016

Aim The aim of this study was to assess how an admission to an acute palliative-supportive care unit (APSCU), may influence the therapeutic trajectory of advanced cancer patients. Methods A consecutive sample of advanced cancer patients admitted to APCU was assessed. The following parameters were collected: patients demographics, including age, gender, primary diagnosis, marital status, and educational level, performance status and reasons for and kind of admission, data about care-givers, recent anticancer treatments, being on/off treatment or uncertain, the previous care setting, who proposed the admission to APSCU. Physical and psychological symptoms were evaluated at admission and at ti…

MaleGenetics and Molecular Biology (all)Palliative careCancer Treatmentlcsh:MedicineMedicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)ToxicologyPathology and Laboratory MedicineBiochemistryCONSECUTIVE SAMPLE0302 clinical medicineNeoplasmsMedicine and Health SciencesMedicine030212 general & internal medicinelcsh:ScienceAnalgesicsMultidisciplinaryPharmaceuticsMedicine (all)Palliative CareHormonal TherapyDrugsHospitalsPatient DischargeHospitalizationOncologyCritical Pathway030220 oncology & carcinogenesisCritical PathwaysMarital statusHormonal therapyFemaleOff TreatmentEnd-of-life careResearch ArticleHumanmedicine.medical_specialtyPatientsAged; Analgesics; Female; Follow-Up Studies; Hospitalization; Humans; Male; Neoplasms; Patient Discharge; Patient Readmission; Cancer Care Facilities; Critical Pathways; Palliative Care; Medicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Cancer Care FacilitiesPatient ReadmissionFollow-Up Studie03 medical and health sciencesDrug TherapyPain ManagementHumansIntensive care medicineAgedPharmacologyBiochemistry Genetics and Molecular Biology (all)ToxicityPerformance statusCancer Care Facilitiebusiness.industrylcsh:RBiology and Life SciencesCancermedicine.diseaseHealth CareOpioidsAgricultural and Biological Sciences (all)Health Care FacilitiesEmergency medicineNeoplasmlcsh:QAnalgesicbusinessFollow-Up Studies
researchProduct

Older women are frailer, but less often die then men: a prospective study of older hospitalized people

2019

Abstract Objectives The association between frailty, mortality and sex is complex, but a limited literature is available on this topic, particularly for older hospitalized patients. Therefore, the objective of our study was to prospectively evaluate sex differences in frailty, assessed by the Multidimensional Prognostic Index (MPI) and mortality, institutionalization, and re-hospitalization in an international cohort of older people admitted to hospital. Study design We used data from nine public hospitals in Europe and Australia, to evaluate sex differences in mortality, frailty and the risk of institutionalization and re-hospitalization, during one year of follow-up. Main outcome measures…

MaleGerontologyMultivariate analysisPrognosiLower riskArticleGeneral Biochemistry Genetics and Molecular BiologyHospital03 medical and health sciences0302 clinical medicineMultidimensional Prognostic IndexHumansMedicineLongitudinal StudiesProspective Studies030212 general & internal medicineProspective cohort studyGeriatric AssessmentAgedAged 80 and overSex Characteristics030219 obstetrics & reproductive medicineFrailtybusiness.industryMortality rateAustraliaObstetrics and GynecologyOdds ratioPrognosisHospitalsPatient DischargeConfidence intervalEuropeHospitalizationSurvival RateCohortSexFemaleCohort studybusinessCohort studyMaturitas
researchProduct

Taste loss in hospitalized multimorbid elderly subjects

2013

ED Toffanello,1 EM Inelmen,1 A Imoscopi,1 E Perissinotto,2 A Coin,1 F Miotto,1 LM Donini,3 D Cucinotta,4 M Barbagallo,5 E Manzato,1 G Sergi11Department of Medical and Surgical Sciences, Geriatrics Division and University of Padova, Padova, 2Department of Environmental Medicine and Public Health, University of Padua, Padua, Italy; 3Department of Medical Physiopathology (Food Science Section), University of Roma, La Sapienza, Roma, 4S Orsola Malpighi Hospital, Bologna, 5Geriatric Unit, Department of Internal Medicine and Emerging Diseases, University of Palermo, Palermo, ItalyBackground: Loss of the sense of taste is common among older people. Morbidities and polypharmacy may contribute to th…

MaleGerontologymedicine.medical_specialtyTasteSettore MED/09 - Medicina Internataste thresholdsHealth StatusmalnutritionTaste DisordersCognitiontaste loss; hospitalized elderly; polypharmacy; taste thresholds; sour stimuli; malnutritionInternal medicinemedicineHumansTaste ThresholdpolypharmacyGeriatric AssessmentAgedOriginal ResearchAged 80 and overPolypharmacyhospitalized elderlybusiness.industryRC952-954.6Taste PerceptionGeneral MedicineOdds ratiomedicine.diseaseConfidence intervaltaste losstaste thresholds taste loss hospitalized elderly sour stimuli polypharmacy malnutritionHospitalizationMalnutritionNutrition AssessmentTaste disorderGeriatricsClinical Interventions in AgingFemaleObservational studyGeriatrics and Gerontologybusinessmalnutrition.sour stimuliClinical Interventions in Aging
researchProduct

Effectiveness of hand hygiene and provision of information in preventing influenza cases requiring hospitalization☆☆☆★

2012

Background The objective of the study was to investigate the effectiveness of non-pharmacological interventions in preventing cases of influenza requiring hospitalization. Methods We performed a multicenter case-control study in 36 hospitals, in 2010 in Spain. Hospitalized influenza cases confirmed by reverse-transcription polymerase chain reaction and three matched controls (two hospital and one community control) per case were selected. The use of non-pharmacological measures seven days before the onset of symptoms (frequency of hand washing, use of alcohol-based hand sanitizers and handwashing after touching contaminated surfaces) was collected. Results We studied 813 cases hospitalized …

MaleHandwashingNon-pharmacological measuresEpidemiologyPsychological interventionInfluenza A Virus H1N1 SubtypeHygieneRisk FactorsEpidemiologyChildmedia_commonTransmission (medicine)Reverse Transcriptase Polymerase Chain ReactionMiddle AgedHospitalizationChild PreschoolFemaleHand DisinfectionAdultmedicine.medical_specialtyHand washingAdolescentmedia_common.quotation_subjectCase control studyHealth PromotionAdministration CutaneousArticleHand sanitizerInfluenza HumanmedicineTransmissionHumansIntensive care medicineInfection Controlbusiness.industryPreventionPublic Health Environmental and Occupational HealthCase-control studyInfant NewbornInfantOdds ratioInfluenzaSocial ClassSpainCase-Control StudiesEmergency medicineAnti-Infective Agents LocalbusinessHand hygieneDisinfectantsPreventive Medicine
researchProduct

Under-detection of delirium and impact of neurocognitive deficits on in-hospital mortality among acute geriatric and medical wards

2015

Abstract Background Delirium is a neuropsychiatric disorder, triggered by medical precipitants causes. Study aims were to describe the prevalence and impact on in-hospital mortality of delirium identified through ICD-9 codes as well as evidence of neurocognitive deficits demonstrated in a population of older patients admitted to acute medical wards. Methods This was a prospective cohort multicenter study of 2521 older patients enrolled in the “Registro Politerapie SIMI (REPOSI)” during the years 2010 and 2012. The diagnosis of delirium was obtained by ICD-9 codes. Cognitive function was evaluated with the Short Blessed Test (SBT) and single SBT items were used as measures of deficits in att…

MaleHealth Knowledge Attitudes PracticePediatricsmedicine.medical_specialtySettore MED/09 - Medicina InternaActivities of daily livingMultivariate analysisUnder-detectionPopulationAcute medical wards delirium neurocognitive deficits older under-detectionSocio-culturaleLogistic regressionbehavioral disciplines and activitiesCognitionAcute medical wardRisk FactorsActivities of Daily Livingmental disordersInternal MedicinemedicineNeurocognitive deficitHumansHospital MortalityProspective StudieseducationProspective cohort studyDelirium Under-detection Neurocognitive deficits Older Acute medical wardsAgedAged 80 and overPsychiatric Status Rating Scaleseducation.field_of_studyAcute medical wardsbusiness.industryDeliriumCognitionnervous system diseasesHospitalizationneurocognitive deficitsOlderLogistic ModelsItalyMultivariate AnalysisDeliriumFemalemedicine.symptombusinessNeurocognitiveEuropean Journal of Internal Medicine
researchProduct

Association of Osteoarthritis with Increased Risk of Cardiovascular Diseases in the Elderly: Findings from the Progetto Veneto Anziano Study Cohort

2015

Objective The possible relevance of osteoarthritis (OA) as a cardiovascular disease (CVD) risk factor is still debated. The aim of this study was to investigate the association between OA and the onset of CVD in older individuals. Methods Among a sample of 3,099 elderly subjects, 2,158 were identified as having no CVD at baseline and were followed up for a mean ± SD 4.4 ± 1.2 years. OA was defined using a standardized algorithm that investigated disease history, medical documentation (including radiographic reports), symptoms, and physical examination of the joints. Incident CVD was defined as the onset of coronary artery disease, heart failure, stroke/transient ischemic attack, peripheral …

MaleIMPACTImmunologyUNITED-STATESPROGRESSIONCoronary Artery DiseaseKNEE OSTEOARTHRITISNOCohort StudiesPeripheral Arterial DiseaseRheumatologyImmunology; Immunology and Allergy; RheumatologyRisk FactorsOsteoarthritisEPIDEMIOLOGYHumansImmunology and AllergyObesityAgedDyslipidemiasProportional Hazards ModelsAged 80 and overHeart FailureDISABILITYMORTALITYIncidencePREVALENCEHospitalizationLipoproteins LDLStrokeATHEROSCLEROSISItalyCardiovascular DiseasesIschemic Attack TransientHypertensionFemaleARTHRITISFollow-Up Studies
researchProduct

Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU

2019

OBJECTIVES To develop a scoring system model that predicts mortality within 30 days of admission of patients older than 80 years admitted to intensive care units (ICUs). DESIGN Prospective cohort study. SETTING A total of 306 ICUs from 24 European countries. PARTICIPANTS Older adults admitted to European ICUs (N = 3730; median age = 84 years [interquartile range = 81‐87 y]; 51.8% male). MEASUREMENTS Overall, 24 variables available during ICU admission were included as potential predictive variables. Multivariable logistic regression was used to identify independent predictors of 30‐day mortality. Model sensitivity, specificity, and accuracy were evaluated with receiver operating characteris…

MaleINTENSIVE-CARE-UNITOrgan Dysfunction Scoresmedicine.medical_treatmentPrognosis.MedizinDECISION-MAKINGLogistic regressionlaw.inventionolder adult0302 clinical medicinePHYSICIANSInterquartile rangelaw80 and overMedicine and Health Sciences030212 general & internal medicineHospital MortalityProspective StudiesProspective cohort studyolder adultsAged 80 and overpredictddc:617Respiration[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyBrief ReportPrognosisIntensive care unitADMISSION3. Good healthEuropeHospitalizationIntensive Care UnitsBrier scoreOlder adultsArtificialFemaleprognosimedicine.medical_specialtycritical care; model; older adults; predict; prognosis; Aged 80 and over; Europe; Female; Hospital Mortality; Hospitalization; Humans; Intensive Care Units; Male; Prospective Studies; Respiration Artificial; Organ Dysfunction Scores; Prognosis03 medical and health sciencesIntensive caremedicineJournal ArticleHumansILL ELDERLY-PATIENTSRenal replacement therapyAgedmodelReceiver operating characteristicbusiness.industry030208 emergency & critical care medicineRespiration Artificialcritical careEmergency medicine[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieBrief ReportsprognosisGeriatrics and Gerontologybusiness
researchProduct

Impact of universal vaccination against varicella in Italy.

2014

In Italy, the introduction of Universal Varicella Vaccination (UVV) has been decided but postponed, as a national programme, until 2015, when data from Regions which have already implemented it will be available. Starting from 2003, eight Italian Regions (Basilicata, Calabria, Friuli Venezia Giulia, Apulia, Sardinia, Sicily, Tuscany and Veneto) have progressively introduced UVV, in their immunization programme, with different schedules in children aged 13–15 months and 5–6 years, currently a two-dose schedule is adopted by all Regions. In June 2013, an Interregional Group on Varicella Vaccination (IGVV) has been established in order to assess the effectiveness of varicella vaccination with …

MaleImmunization ProgramsHealth PolicyIncidenceimmunization coverageVaccinationUniversal Varicella VaccinationInfantnotificationsadverse events following varicella immunizationVaricellaChickenpox VaccineHospitalizationChickenpoxItalyChild PreschoolHumansFemaleHealth Services ResearchChildhospitalizationsResearch PaperHuman vaccinesimmunotherapeutics
researchProduct

Gout, allopurinol intake and clinical outcomes in the hospitalized multimorbid elderly.

2014

Background: Increased serum uric acid has been considered a cardiovascular risk factor but no study has assessed its relation with hospital mortality or length of stay. On the basis of data obtained from a prospective registry, the prevalence of gout/hyperuricemia and its association with these and other clinical parameters was evaluated in an Italian cohort of elderly patients acutely admitted to internal medicine or geriatric wards. Methods: While the prevalence of gout was calculated by counting patients with this diagnosis hyperuricemia was inferred in patients taking allopurinol at hospital admission or discharge, on the assumption that this drug was only prescribed owing to the findin…

MaleKidney DiseaseSettore MED/09 - Medicina InternahyperuricemiaComorbiditieschemistry.chemical_compoundCardiovascular Diseasegout elderlyAllopurinol; Comorbidities; Elderly; Gout; Hyperuricemia; Outcomes; Age Factors; Aged; Aged 80 and over; Allopurinol; Cardiovascular Diseases; Chronic Disease; Comorbidity; Female; Gout; Hospital Mortality; Hospitalization; Humans; Hyperuricemia; Kidney Diseases; Length of Stay; Male; Treatment Outcome; Uric Acid; Internal Medicine; Medicine (all)80 and overMedicineAge FactorHyperuricemiaHospital MortalityOutcomeAged 80 and overOUTCOMESMedicine (all)Age FactorsHospitalizationcomorbidityTreatment OutcomeCardiovascular DiseasesAllopurinol; Comorbidities; Elderly; Gout; Hyperuricemia; OutcomesCohortFemaleKidney DiseasesComorbiditieAllopurinol; Comorbidities; Elderly; Gout; Hyperuricemia; Outcomes; Age Factors; Aged; Aged 80 and over; Allopurinol; Cardiovascular Diseases; Chronic Disease; Comorbidity; Female; Gout; Hospital Mortality; Hospitalization; Humans; Hyperuricemia; Kidney Diseases; Length of Stay; Male; Treatment Outcome; Uric AcidHumanmedicine.drugmusculoskeletal diseasesmedicine.medical_specialtycongenital hereditary and neonatal diseases and abnormalitiesAllopurinolAllopurinol; Comorbidities; Elderly; Gout; Hyperuricemia; Outcomes; Age Factors; Aged; Aged 80 and over; Allopurinol; Cardiovascular Diseases; Chronic Disease; Comorbidity; Female; Gout; Hospital Mortality; Hospitalization; Humans; Hyperuricemia; Kidney Diseases; Length of Stay; Male; Treatment Outcome; Uric Acid; Internal MedicineallopurinolNOgoutGout allopurinol hyperuricemia comorbidities outcomes elderlyInternal medicineInternal MedicineHumansRisk factorIntensive care medicineAdverse effectAgedELDERLYgout allopurinol hyperuricemia comorbidities outcomes elderlybusiness.industrynutritional and metabolic diseasesLength of Staymedicine.diseaseComorbidityGoutUric AcidchemistryChronic DiseaseUric acidbusiness
researchProduct