Search results for "Hap"
showing 10 items of 2767 documents
Haptic and Visual Feedback Assistance for Dual-Arm Robot Teleoperation in Surface Conditioning Tasks
2020
Contact driven tasks, such as surface conditioning operations (wiping, polishing, sanding, etc.), are difficult to program in advance to be performed autonomously by a robotic system, specially when the objects involved are moving. In many applications, human-robot physical interaction can be used for the teaching, specially in learning from demonstrations frameworks, but this solution is not always available. Robot teleoperation is very useful when user and robot cannot share the same workspace due to hazardous environments, inaccessible locations, or because of ergonomic issues. In this sense, this article introduces a novel dual-arm teleoperation architecture with haptic and visual feedb…
Re-forming end-of-life components through single point incremental forming
2020
Abstract Applying Circular Economy strategies is mandatory to face material demand while minimizing the environmental impact. Manufacturing processes are to be thought as means to enable material/component reuse strategies. This paper presents the suitability of Single Point Incremental Forming (SPIF) to re-form End-of-life sheet metal components. Deep drawing followed by SPIF process on aluminium alloys were carried out to simulate reforming processes chain. The resulting thinning and strain distributions were experimentally analysed for different configurations. The research proves that the local action and enhanced formability nature of SPIF allow non-homogeneously thinned and reduced fo…
Manufacturing strategies for efficiency in energy and resources use: The role of metal shaping processes
2017
Abstract Manufacturing sector nowadays has to deal with the global need to reduce the environmental impact of human activity. As manufacturing accounts for a significant portion of the global CO 2 emissions, scientific research should be addressed to understand the environmental impact of manufacturing processes and, in the meantime, to take advantage of their full potential in reducing the overall CO 2 emissions. The present review paper aims at describing the role of metal shaping processes in reducing the environmental impact across different stages of metal components life. Actually, an increased consciousness concerning both the environmental performances of manufacturing processes and…
Image Enhancement Algorithm for Optical Microstructural Characterization of Shape Memory TiNi Friction Stir Processed
2017
Abstract A key topic regarding TiNi alloys concerns the possibility to attain junctions that preserve the shape memory properties of material. Experimental tests, previously performed on TiNi sheet friction stir processed, have highlighted the need to develop an appropriate image analysis method to quantify the various phases percentages present in the characteristics zones of Friction Stir Welding process. A proper Image Processing procedure has been performed in order to quantify the amount of the martensitic phase and to detect its morphology modification along to the processed region. Particularly each micrographic image, firstly, has been denoised using the 2D Wavelet transform techniq…
Assessing the influence of fieldshaper material on magnetic pulse welded interface of Al/Cu joints
2019
Abstract Fieldshaper (FS) is a widely used component in magnetic pulse forming and welding to improve the efficiency of the process. It enables to increase the magnetic pressure experienced by the workpieces during forming and welding. Recent developments in this subject focuses to increase the life time of the fieldshaper and to improve the efficiency by introducing shape optimized designs. In this study, we compare the efficiency of four fieldshapers made of Cuprofor, Siclanic, CuBe2 and Steel. The main focus is given to the effect of material properties while the same geometry was considered for those four fieldshapers. The same welding conditions (discharge voltage of 6kV and air gap of…
X-ray response of CdZnTe detectors grown by the vertical Bridgman technique: Energy, temperature and high flux effects
2016
Abstract Nowadays, CdZnTe (CZT) is one of the key materials for the development of room temperature X-ray and gamma ray detectors and great efforts have been made on both the device and the crystal growth technologies. In this work, we present the results of spectroscopic investigations on new boron oxide encapsulated vertical Bridgman (B-VB) grown CZT detectors, recently developed at IMEM-CNR Parma, Italy. Several detectors, with the same electrode layout (gold electroless contacts) and different thicknesses (1 and 2.5 mm), were realized: the cathode is a planar electrode covering the detector surface (4.1×4.1 mm2), while the anode is a central electrode (2×2 mm2) surrounded by a guard-rin…
Digital fast pulse shape and height analysis on cadmium-zinc-telluride arrays for high-flux energy-resolved X-ray imaging.
2017
Cadmium-zinc-telluride (CZT) arrays with photon-counting and energy-resolving capabilities are widely proposed for next-generation X-ray imaging systems. This work presents the performance of a 2â...mm-thick CZT pixel detector, with pixel pitches of 500 and 250â...μm, dc coupled to a fast and low-noise ASIC (PIXIE ASIC), characterized only by the preamplifier stage. A custom 16-channel digital readout electronics was used, able to digitize and process continuously the signals from each output ASIC channel. The digital system performs on-line fast pulse shape and height analysis, with a low dead-time and reasonable energy resolution at both low and high fluxes. The spectroscopic response …
Techniques to Analyze sRNA Protein Cofactor Self-Assembly In Vitro
2018
Post-transcriptional control of gene expression by small regulatory noncoding RNA (sRNA) needs protein accomplices to occur. Past research mainly focused on the RNA chaperone Hfq as cofactor. Nevertheless, recent studies indicated that other proteins might be involved in sRNA-based regulations. As some of these proteins have been shown to self-assemble, we describe in this chapter protocols to analyze the nano-assemblies formed. Precisely, we focus our analysis on Escherichia coli Hfq as a model, but the protocols presented here can be applied to analyze any polymer of proteins. This chapter thus provides a guideline to develop commonly used approaches to detect prokaryotic protein self-ass…
Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer
2020
Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related death, and 7% of registered malignancies. Sorafenib is the first line molecular targeted therapy for patients in advanced stage of HCC. The present study shows that Sorafenib exerts free radical scavenging properties associated with the downregulation of nuclear factor E2-related factor 2 (Nrf2)-regulated thioredoxin 1 (Trx1) expression in liver cancer cells. The experimental downregulation and/or overexpression strategies showed that Trx1 induced activation of nitric oxide synthase (NOS) type 3 (NOS3) and S-nitrosation (SNO) of CD95 rece…
Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function.
2021
This study was funded by grants from the Ministerio de Economia, Industria y Competitividad y por el Fondo de Desarrollo Regional FEDER, Spain nº SAF2013-49019, SAF2017-85903-P, and from the Consejería de Innovación, Ciencia y Empresa, Junta de Andalucía (P07- CTS- 03135, P10- CTS- 5784, and CTS- 101), Spain. J.F. and L.M. have FPU fellowships from the Ministerio de Educación Cultura y Deporte, Spain. C.R.S. was a schorlarship holder from the Plan Propio de Investigación of the University of Granada.