Search results for "Hazards"

showing 10 items of 785 documents

Social frailty increases the risk of all-cause mortality: A longitudinal analysis of the English Longitudinal Study of Ageing

2022

Objectives\ud Social frailty is a common condition in older people, but its consequences are largely unknown. Therefore, in this longitudinal analysis, we aimed to investigate the association between social frailty and risk of all-cause mortality in a large sample of older people.\ud Design\ud Longitudinal, cohort.\ud Settings and participants\ud Older people participating to the English Longitudinal Study of Ageing (ELSA).\ud Methods\ud Social frailty was defined based on financial difficulty, household status, social activity, and contacts with other people: social frailty was defined as ≥2 points, social pre-frailty (1 point), and robustness (0 points). Survival status during ten years o…

AgingFrailtyFrail ElderlyCell BiologyBiochemistryCohort StudiesEndocrinologyCohort ELSA Frailty Living alone Longitudinal Mortality Older people Poverty Social frailtyGeneticsHumansLongitudinal StudiesGeriatric AssessmentMolecular BiologyAgedProportional Hazards ModelsExperimental Gerontology
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Development and validation of prediction model to estimate 10-year risk of all-cause mortality using modern statistical learning methods: a large pop…

2021

Abstract Background In increasingly ageing populations, there is an emergent need to develop a robust prediction model for estimating an individual absolute risk for all-cause mortality, so that relevant assessments and interventions can be targeted appropriately. The objective of the study was to derive, evaluate and validate (internally and externally) a risk prediction model allowing rapid estimations of an absolute risk of all-cause mortality in the following 10 years. Methods For the model development, data came from English Longitudinal Study of Ageing study, which comprised 9154 population-representative individuals aged 50–75 years, 1240 (13.5%) of whom died during the 10-year follo…

AgingLongitudinal studySurvivalEpidemiologyCalibration (statistics)PopulationHealth InformaticsFeature selectionAbsolute riskPopulation-based longitudinal studyPrognostic factorsRisk AssessmentSensitivity and Specificity01 natural sciencesCohort Studies010104 statistics & probability03 medical and health sciences0302 clinical medicineStatisticsHumansMedicineLongitudinal Studies030212 general & internal medicineMortality0101 mathematicseducationAgedProportional Hazards Modelslcsh:R5-920education.field_of_studyProportional hazards modelbusiness.industryAbsolute risk reductionHealth and Retirement StudyStatistical learninglcsh:Medicine (General)businessResearch ArticleCohort studyBMC Medical Research Methodology
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Coimpairments as Predictors of Severe Walking Disability in Older Women

2001

OBJECTIVE: Severe disabilities are common among older people who have impairments in a range of physiologic systems. It is not known, however, whether the presence of multiple impairments, or coimpairments, is associated with increased risk of developing new disability. The aim of this study was to determine the combined effects of two impairments, decreased knee-extension strength and poor standing balance, on the risk of developing severe walking disability among older, moderately-to-severely disabled women who did not have severe walking disability at baseline. DESIGN: The Women's Health and Aging Study is a 3-year prospective study with 6 semi-annual follow-up data-collection rounds fol…

Agingmedicine.medical_specialtyTime FactorsKnee JointPosturePoison controlComorbidityWalkingDisability EvaluationInjury preventionmedicinePostural BalanceHumansProspective StudiesProspective cohort studyGaitPostural BalanceAgedBalance (ability)Aged 80 and overProportional hazards modelbusiness.industryIncidencePreferred walking speedRelative riskPhysical therapyFemaleGeriatrics and Gerontologybusinesshuman activitiesFollow-Up StudiesMuscle ContractionJournal of the American Geriatrics Society
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Combined resistance and balance-jumping exercise reduces older women's injurious falls and fractures: 5-year follow-up study

2014

BACKGROUND AND OBJECTIVE: previously, a randomised controlled exercise intervention study (RCT) showed that combined resistance and balance-jumping training (COMB) improved physical functioning and bone strength. The purpose of this follow-up study was to assess whether this exercise intervention had long-lasting effects in reducing injurious falls and fractures. DESIGN: five-year health-care register-based follow-up study after a 1-year, four-arm RCT. SETTING: community-dwelling older women in Finland. SUBJECTS: one hundred and forty-five of the original 149 RCT participants; women aged 70-78 years at the beginning. METHODS: participants' health-care visits were collected from computerised…

Agingmedicine.medical_specialtyTime FactorsPoison controlKaplan-Meier Estimatelaw.inventionFractures Bonesymbols.namesakeRandomized controlled trialRisk FactorslawOdds RatiomedicineHumansMuscle StrengthProspective StudiesRegistriesPoisson regressionProspective cohort studyGeriatric AssessmentPostural BalanceExerciseFinlandAgedProportional Hazards ModelsProportional hazards modelbusiness.industryIncidenceHazard ratioAge FactorsResistance Trainingta3141General MedicineOdds ratioInjurious fallsTreatment OutcomeOlder adultsRelative risksymbolsPhysical therapyWomen's HealthAccidental FallsFemaleIndependent LivingGeriatrics and GerontologybusinessFracturesFollow-Up StudiesAge and Ageing
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Assessment of natural hazards in urban planning policies of the municipalities in the province of Alicante (Spain). Legislation and risk mapping

2018

Los espacios urbanos se han convertido en territorios proclives al daño económico y pérdida de vidas humanas con ocasión de episodios de rango extremo de origen natural. Ello es debido a la acumulación de población y actividades en el medio urbano y a la deficiente planificación urbana, que no ha tenido en cuenta, hasta fechas muy recientes, el problema de la peligrosidad natural y sus efectos territoriales en los procesos de asignación de usos en el suelo. El objetivo de esta investigación es analizar el grado de cumplimiento de la obligación de incorporar cartografía de riesgo en la documentación de planeamiento urbanístico en la provincia de Alicante a partir de 2008. Para ello, se ha co…

Alicanteeducation.field_of_studyLand useWelfare economicsHuman lifeGeography Planning and DevelopmentPopulationNatural hazardsCartografía de riesgos naturalesPeligros naturalesGeographyUrban planningNatural hazardOrdenación del territorioAnálisis Geográfico RegionalNatural risk cartographyLand-use planningeducationUrban managementSpatial planningEarth-Surface Processes
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Adherence to antithrombotic therapy guidelines improves mortality among elderly patients with atrial fibrillation: insights from the REPOSI study

2016

Background: Atrial fibrillation (AF) is associated with a substantial risk of thromboembolism and mortality, significantly reduced by oral anticoagulation. Adherence to guidelines may lower the risks for both all cause and cardiovascular (CV) deaths. Methods: Our objective was to evaluate if antithrombotic prophylaxis according to the 2012 European Society of Cardiology (ESC) guidelines is associated to a lower rate of adverse outcomes. Data were obtained from REPOSI; a prospective observational study enrolling inpatients aged ≥65 years. Patients enrolled in 2012 and 2014 discharged with an AF diagnosis were analysed. Results: Among 2535 patients, 558 (22.0 %) were discharged with a diagnos…

Antithrombotic therapy; Atrial fibrillation; Elderly; Guidelines; Outcomes; Cardiology and Cardiovascular MedicineMaleRegistrieTime Factorsantithrombotic therapy; atrial fibrillation; elderly; guidelines; outcomesAtrial fibrillation (AF)Practice PatternsKaplan-Meier Estimate030204 cardiovascular system & hematologyGuidelineoutcomesCoronary artery disease0302 clinical medicineElderlyRisk FactorsAtrial FibrillationAntithrombotic80 and overAge Factor030212 general & internal medicineRegistriesguidelinesAntithrombotic therapy Atrial fibrillation Elderly Guidelines OutcomesPractice Patterns Physicians'OutcomeAged 80 and overFibrinolytic AgentAge FactorsAtrial fibrillationGeneral MedicineTreatment OutcomeItalyAtrial fibrillation (AF) thromboembolism antithrombotic prophylaxisPractice Guidelines as TopicCardiologyFemaleGuideline AdherenceCardiology and Cardiovascular MedicineHumanAntithrombotic therapy; Atrial fibrillation; Elderly; Guidelines; Outcomes; Age Factors; Aged; Aged 80 and over; Atrial Fibrillation; Chi-Square Distribution; Female; Fibrinolytic Agents; Guideline Adherence; Humans; Italy; Kaplan-Meier Estimate; Logistic Models; Male; Practice Patterns Physicians'; Proportional Hazards Models; Registries; Risk Assessment; Risk Factors; Thromboembolism; Time Factors; Treatment Outcome; Practice Guidelines as Topic; Cardiology and Cardiovascular Medicinemedicine.medical_specialtyLogistic ModelTime FactorSocio-culturaleLower riskRisk Assessment03 medical and health sciencesFibrinolytic AgentsInternal medicineThromboembolismmedicineHumansProportional Hazards ModelsAgedAntithrombotic therapyPhysicians'Chi-Square Distributionbusiness.industryProportional hazards modelRisk FactorSettore MED/09 - MEDICINA INTERNAGuidelinethromboembolismmedicine.diseaseAtrial fibrillationLogistic ModelsProportional Hazards Modelantithrombotic prophylaxisbusinessChi-squared distributionFibrinolytic agent
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Outcomes of aortic valve repair according to valve morphology and surgical techniques

2012

OBJECTIVES: The aim of this study was to assess the impact of aortic valve morphology and different surgical aortic valve repair techni- ques on long-term clinical outcomes. METHODS: Between February 2003 and May 2010, 216 patients with aortic insufficiency underwent aortic valve repair in our institu- tion. Ages ranged between 26 and 82 years (mean 53 ± 15 years). Aortic valve dysfunctions, according to functional classification, were: type I in 55 patients (25.5%), type II in 126 (58.3%) and type III in 35 (16.2%). Sixty-six patients (27.7%) had a bicuspid valve. Aortic valve repair techniques included sub-commissural plasty in 138 patients, plication in 84, free-edge reinforcement in 80,…

Aortic valveMaleTime Factorsmedicine.medical_treatmentKaplan-Meier EstimateAortic valve repairRecurrenceRisk FactorsMitral valve80 and overHospital MortalityCoronary Artery BypassAortaUltrasonographyAged 80 and overTricuspid valveCalcinosisCardiac Valve AnnuloplastyMiddle AgedAortic valve repair • Bicuspid aortic valve • Tricuspid aortic valve • Aortic annulus stabilization medicine.anatomical_structureTreatment OutcomeAortic ValveReplantationcardiovascular systemCardiologyChordae TendineaeMitral ValveFemaleChordae tendineaeCardiology and Cardiovascular MedicineAdult; Aged; Aged 80 and over; Aorta; Aortic Valve; Aortic Valve Insufficiency; Blood Vessel Prosthesis Implantation; Calcinosis; Chordae Tendineae; Coronary Artery Bypass; Disease-Free Survival; Female; Hospital Mortality; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mitral Valve; Proportional Hazards Models; Recurrence; Replantation; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography; Cardiac Valve Annuloplasty; Suture TechniquesPulmonary and Respiratory MedicineAdultmedicine.medical_specialtyAortic Valve InsufficiencyRisk AssessmentCardiac Valve AnnuloplastyDisease-Free SurvivalBlood Vessel Prosthesis ImplantationBicuspid valveInternal medicinemedicineHumansAgedProportional Hazards ModelsMitral valve repairbusiness.industrySuture TechniquesSettore MED/23 - Chirurgia CardiacaOriginal ArticlesSurgerySurgerybusiness
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The size of juxtaluminal hypoechoic area in ultrasound images of asymptomatic carotid plaques predicts the occurrence of stroke

2013

Abstract OBJECTIVE: To test the hypothesis that the size of a juxtaluminal black (hypoechoic) area (JBA) in ultrasound images of asymptomatic carotid artery plaques predicts future ipsilateral ischemic stroke. METHODS: A JBA was defined as an area of pixels with a grayscale value 10 mm(2) (P 8 mm(2)) was still significant after adjusting for other plaque features known to be associated with increased risk, including stenosis, grayscale median, presence of discrete white areas without acoustic shadowing indicating neovascularization, plaque area, and history of contralateral TIA or stroke. Plaque area and grayscale median were not significant. Using the significant variables (stenosis, discr…

Asymptomatic carotid plaqueMaleTime Factorsmedicine.medical_treatmentCarotid endarterectomyKaplan-Meier EstimateSeverity of Illness Indexasymptomatic carotid artery stenosis; hypoecoic area; StrokeRisk FactorsCarotid StenosisUltrasonography Doppler ColorProspective cohort studyStrokeAged 80 and overNeovascularization Pathologichypoecoic areaMiddle AgedPrognosisPlaque AtheroscleroticEuropeStrokeIschemic Attack TransientPredictive value of testsFemaleRadiologymedicine.symptomjuxtaluminal hypoechoic area ultrasound images asymptomatic carotid plaques strokeCardiology and Cardiovascular MedicineCarotid Artery InternalAdultmedicine.medical_specialtyAsymptomaticRisk AssessmentAsymptomatic carotid plaque; Brain ischemia; Stroke; EchographyBrain ischemiaPredictive Value of Testsasymptomatic carotid artery stenosimedicineHumanscardiovascular diseasesAgedProportional Hazards Modelsbusiness.industryProportional hazards modelmedicine.diseaseAcoustic shadowSettore MED/11 - Malattie Dell'Apparato CardiovascolareStenosisROC CurveAsymptomatic DiseasesLinear ModelsSurgeryasymptomatic carotid artery stenosisEchographybusinessFollow-Up Studies
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Aviation Contrail Cirrus and Radiative Forcing Over Europe During 6 Months of COVID‐19

2021

Abstract The COVID‐19 pandemic led to a 72% reduction of air traffic over Europe in March–August 2020 compared to 2019. Modeled contrail cover declined similarly, and computed mean instantaneous radiative contrail forcing dropped regionally by up to 0.7 W m−2. Here, model predictions of cirrus optical thickness and the top‐of‐atmosphere outgoing longwave and reflected shortwave irradiances are tested by comparison to Meteosat‐SEVIRI‐derived data. The agreement between observations and modeled data is slightly better when modeled contrail cirrus contributions are included. The spatial distributions and diurnal cycles of the differences in these data between 2019 and 2020 are partially caused…

Atmospheric Science010504 meteorology & atmospheric sciencesPollution: Urban Regional and GlobalcirrusForcing (mathematics)Atmospheric Composition and Structure010502 geochemistry & geophysicsAtmospheric sciencesBiogeosciences01 natural sciencesOceanography: Biological and ChemicalCloud/Radiation InteractionRadiative transferWolkenphysikInstitut für Physik der AtmosphäreMarine PollutioncontrailOceanography: GeneralGeophysicsPollution: Urban and RegionalAtmospheric ProcessesCirrusClouds and AerosolssatelliteMegacities and Urban Environmentcontrail aircraft climate observation model traffic Meteosat CoCiPRadiation: Transmission and ScatteringAtmospherePaleoceanographyEvolution of the EarthCOVID‐19Research LetterGlobal ChangeBiosphere/Atmosphere InteractionsUrban Systems0105 earth and related environmental sciencesEvolution of the AtmosphereAerosolsradiative forcingVerkehrsmeteorologieAtmosphereLongwaveAtmosphärische SpurenstoffeRadiative forcingAerosols and ParticlesNumerical weather predictionTectonophysicsaviationGeneral Earth and Planetary SciencesEnvironmental scienceShortwaveNatural HazardsGeophysical Research Letters
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Radio emissions from double RHESSI TGFs

2016

Abstract A detailed analysis of Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) terrestrial gamma ray flashes (TGFs) is performed in association with World Wide Lightning Location Network (WWLLN) sources and very low frequency (VLF) sferics recorded at Duke University. RHESSI clock offset is evaluated and found to experience changes on the 5 August 2005 and 21 October 2013, based on the analysis of TGF‐WWLLN matches. The clock offsets were found for all three periods of observations with standard deviations less than 100 μs. This result opens the possibility for the precise comparative analyses of RHESSI TGFs with the other types of data (WWLLN, radio measurements, etc.) In ca…

Atmospheric ScienceHigh energy010504 meteorology & atmospheric sciencesAtmospheric ElectricityFOS: Physical sciencesRHESSI clock offsetterrestrial gamma ray flashesAstrophysicsRadio atmospheric01 natural sciencesLightningPhysical Geography and Environmental GeoscienceAerosol and CloudsAtmospheric SciencesRemote SensingPhysics - Space Physics0103 physical sciencesEarth and Planetary Sciences (miscellaneous)Instruments and TechniquesVery low frequency010303 astronomy & astrophysicsResearch ArticlesTGF‐WWLLN match0105 earth and related environmental sciencesRadiative ProcessesPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Remote Sensing and DisastersGamma raymultipeak TGFsWorld wideLightningRHESSI TGFsSpace Physics (physics.space-ph)Geophysicsradio emission from TGFClock offset13. Climate actionSpace and Planetary ScienceAtmospheric ProcessesAstrophysics - High Energy Astrophysical PhenomenaNatural HazardsResearch Article
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