Search results for "Head"

showing 10 items of 1640 documents

Salivary flow and xerostomia in patients with type 2 diabetes

2018

Background: Saliva is secreted by the major and minor salivary glands. There are a number of physiological factors that can reduce this secretion such as age, sex, body weight, number of teeth present in the mouth or time of day. This decrease may also be caused by the use of certain drugs, radiotherapy for head and neck cancer, chronic rheumatic diseases such as Sjögren's syndrome and other systemic disorders such as diabetes mellitus (DM). Objective of this study was to investigate the effect of type 2 DM on salivary secretion and its relation to the sensation of xerostomia. Methods: Forty-seven patients with type 2 DM and 46 healthy individuals, aged 40-80, participated in the study. Sam…

AdultMaleCancer Researchmedicine.medical_specialtySalivadiabetes mellitus type 2saliva xerostomia diabetes mellitus type 22734030209 endocrinology & metabolismStimulationType 2 diabetesSalivary GlandsPathology and Forensic MedicineNO03 medical and health sciencessymbols.namesake0302 clinical medicinestomatognathic systemSurveys and QuestionnairesInternal medicineDiabetes mellitusSensationmedicineHumansxerostomiaFisher's exact testAgedAged 80 and overMealsalivabusiness.industryOtorhinolaryngology2734 Pathology and Forensic MedicineHead and neck cancerMED/28 - MALATTIE ODONTOSTOMATOLOGICHE030206 dentistryMiddle Agedmedicine.diseasestomatognathic diseasesDiabetes Mellitus Type 2OtorhinolaryngologysymbolsPeriodonticsFemaleOral Surgerybusiness
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Vinorelbine plus cisplatin in recurrent or previously untreated unresectable squamous cell carcinoma of the head and neck

1995

Despite considerable progress achieved in the management of head and neck carcinomas (HNC) in the last decade, the prognosis of patients with advanced squamous cell HNC is still dismal. On the basis of the reported good activity of a new vinca alkaloid derivative, i.e., vinorelbine (VNR), we tested the combination of cisplatin and VNR in a series of patients with recurrent or previously untreated unresectable squamous cell HNC. Thirty-five patients with recurrent or previously untreated unresectable squamous cell HNC were treated with a combination of cisplatin 80 mg/m2 on day 1, plus vinorelbine 25 mg/m2 i.v. push on days 1 and 8. This cycle was repeated every 3 weeks. Analysis of response…

AdultMaleCancer Researchmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentVinblastineVinorelbineGastroenterologyDrug Administration ScheduleVinca alkaloidInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansAgedCisplatinChemotherapybusiness.industryRemission InductionVinorelbineMiddle AgedVinblastineSurgeryRadiation therapyRegimenOncologyHead and Neck NeoplasmsCarcinoma Squamous CellVomitingFemaleCisplatinNeoplasm Recurrence Localmedicine.symptombusinessmedicine.drug
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Neo-adjuvant chemo-(immuno-)therapy of advanced squamous-cell head and neck carcinoma: a multicenter, phase III, randomized study comparing cisplatin…

1998

We carried out an open, randomized, phase III, multicenter clinical trial to compare, in neo-adjuvant setting, the clinical response and toxicity of the combination chemotherapy cisplatin + 5-FU with the same combination plus s.c. recombinant interleukin-2 (rIL-2) in patients with advanced (stage III IV) head and neck squamous-cell carcinoma (HNSCC). Regimen A was the classical Al Sarraf treatment: 100 mg/m2 cisplatin i.v. on day 1 plus 1000 mg m(-2) day(-1) 5-FU on days 1-5 as a continuous infusion. Regimen B was the same as regimen A plus 4.5 MIU/day rIL-2 s.c. on days 8-12 and 15-19. Treatment was repeated every 3 weeks for three cycles. A total of 33 patients were enrolled in the study;…

AdultMaleCancer Researchmedicine.medical_specialtymedicine.medical_treatmentImmunologyAntineoplastic AgentsGastroenterologyGroup Blaw.inventionRandomized controlled triallawInternal medicinemedicineHumansImmunology and AllergyAgedChemotherapybusiness.industryCombination chemotherapyMiddle Agedmedicine.diseaseRecombinant ProteinsSurgeryRegimenOncologyEpidermoid carcinomaHead and Neck NeoplasmsFluorouracilCarcinoma Squamous CellInterleukin-2Drug Therapy CombinationFemaleFluorouracilCisplatinbusinessProgressive diseasemedicine.drugCancer Immunology, Immunotherapy
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Protective effect of amifostine on dental health after radiotherapy of the head and neck.

2000

Abstract Purpose: The cytoprotective agent amifostine has been shown to reduce the radiation-induced acute and chronic xerostomia in head and neck cancer patients. The purpose of this study was to evaluate whether or not amifostine also reduces the incidence of dental caries associated with the radiation-induced xerostomia. Methods and Materials: The dental status before and 1 year after radiotherapy was retrospectively compared in 35 unselected patients treated as part of the prospective randomized and multicenter open-label Phase III study (WR-38) at the University Hospitals of Heidelberg, Freiburg, and Erlangen. The WR-38 study compared radiotherapy in head and neck cancer with and witho…

AdultMaleCancer Researchmedicine.medical_specialtymedicine.medical_treatmentRadiation-Protective AgentsDental CariesXerostomiasymbols.namesakeAmifostinestomatognathic systemOral and maxillofacial pathologymedicineClinical endpointHumansRadiology Nuclear Medicine and imagingProspective StudiesRadiation InjuriesFisher's exact testAgedRetrospective StudiesRadiationbusiness.industryHead and neck cancerCase-control studyAmifostineMiddle Agedmedicine.diseaseSurgeryRadiation therapystomatognathic diseasesOncologyHead and Neck NeoplasmsConcomitantsymbolsFemalebusinessmedicine.drugInternational journal of radiation oncology, biology, physics
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Impact force and time analysis influenced by execution distance in a roundhouse kick to the head in taekwondo.

2011

The execution distance is a tactic factor that affects mechanical performance and execution technique in taekwondo. This study analyzes the roundhouse kick to the head by comparing the maximum impact force, execution time, and impact time in 3 distances according to the athletes' competition level. It also analyzes the relationship between impact force and weight in each group. It examines whether the execution distance affects the maximum impact force, execution time, and impact time, in each level group or 2 different competition levels. Participants were 27 male taekwondo players (13 medallists and 14 nonmedallists). The medallists executed the roundhouse kick to the head with greater im…

AdultMaleCompetition levelComputer scienceHead (linguistics)Impact timeOffensivePhysical Therapy Sports Therapy and RehabilitationGeneral MedicineExecution timeBiomechanical PhenomenaYoung AdultTask Performance and AnalysisHumansOrthopedics and Sports MedicineImpactHeadSimulationMartial ArtsJournal of strength and conditioning research
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Treatment of tension-type headache with articulatory and suboccipital soft tissue therapy: A double-blind, randomized, placebo-controlled clinical tr…

2013

This study researches the effectiveness of two manual therapy treatments focused on the suboccipital region for tension-type headache. A randomized double-blind clinical trial was conducted over a period of four weeks with a follow-up at one month. Eighty-four patients with a mean age of 39.7 years (SD 11.4) with tension-type headache were assigned to 4 groups which included the following manual therapy treatment: suboccipital soft tissue inhibition; occiput-atlas-axis global manipulation; combination of both techniques; and a control group. The primary assessment consisted of collecting socio-demographic data and headache characteristics in a one-month base period, data such as age, gender…

AdultMaleComplementary and Manual TherapySoft tissue therapymedicine.medical_specialtyAdolescentPhysical Therapy Sports Therapy and RehabilitationPlaceboDouble blindYoung AdultSex FactorsDouble-Blind MethodmedicineHumansPain ManagementTherapy Soft TissueAgedbusiness.industryTension-Type HeadacheRehabilitationAge FactorsPatient AcuitySoft tissueMiddle AgedMusculoskeletal ManipulationsSurgeryIntensity (physics)Clinical trialComplementary and alternative medicineFemaleHeadachesmedicine.symptomManual therapybusinessJournal of Bodywork and Movement Therapies
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Exploring the switching of the focus of attention within working memory: A combined event-related potential and behavioral study.

2018

Abstract Working memory enables humans to maintain selected information for cognitive processes and ensures instant access to the memorized contents. Theories suggest that switching the focus of attention between items within working memory realizes the access. This is reflected in object-switching costs in response times when the item for the task processing is to be changed. Another correlate of attentional allocation in working memory is the P3a-component of the human event-related potential. The aim of this study was to demonstrate that switching of attention within working memory is a separable processing step. Participants completed a cued memory-updating task in which they were instr…

AdultMaleComputer science050105 experimental psychologyTask (project management)03 medical and health sciencesP3aExecutive FunctionYoung Adult0302 clinical medicineEvent-related potentialPhysiology (medical)Humans0501 psychology and cognitive sciencesAttentionEvoked PotentialsCued speechCerebral CortexFocus (computing)Working memoryGeneral Neuroscience05 social sciencesCognitionElectroencephalographyEvent-Related Potentials P300Inhibition PsychologicalNeuropsychology and Physiological PsychologyMemory Short-TermPattern Recognition VisualResearch DesignHead startSpace PerceptionFemaleCues030217 neurology & neurosurgeryPsychomotor PerformanceCognitive psychologyInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology
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Influence of skeletal class in the morphology of cervical vertebrae: A study using cone beam computed tomography

2016

ABSTRACT Objectives: To quantify the prevalence of cervical vertebrae anomalies and to analyze any association between them and skeletal malocclusions or head posture positions in the same study. Materials and Methods: Two hundred forty patients who were attending the Department of Orthodontics of the University of Valencia for orthodontic treatment were selected and divided into three groups: skeletal Class I (control group, 0° <ANB < 4°), Class II (ANB ≥ 4°), and Class III (ANB ≤ 0°) according to ANB Steiner angle. The morphology of the first five cervical vertebrae was analyzed with cone beam computed tomography to identify any anomalies. Intra- and interobserver error meth…

AdultMaleCone beam computed tomographyCephalometryDentistryOrthodonticsMalocclusion Angle Class IMandibleDehiscenceMalocclusion Angle Class IIStatistics Nonparametric03 medical and health sciences0302 clinical medicineIncisormedicineMaxillaHumansOrthodonticsbusiness.industry030206 dentistryOriginal ArticlesCraniometryCone-Beam Computed TomographySkeletal classmedicine.diseaseIncisormedicine.anatomical_structureMalocclusion Angle Class IIIMaxillaCervical VertebraeFemaleMalocclusionAnatomic LandmarksbusinessHead030217 neurology & neurosurgeryMalocclusionCervical vertebrae
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Unconscious response priming during continuous flash suppression.

2017

Continuous flash suppression (CFS) has become a popular tool for studying unconscious processing, but the level at which unconscious processing of visual stimuli occurs under CFS is not clear. Response priming is a robust and well-understood phenomenon, in which the prime stimulus facilitates overt responses to targets if the prime and target are associated with the same response. We used CFS to study unconscious response priming of shape: arrows with left or right orientation served as primes and targets. The prime was presented near the limen of consciousness and each trial was followed by subjective rating of visibility and a forced-choice response concerning the orientation of the prime…

AdultMaleConsciousnessVisionImaging TechniquesCognitive Neurosciencelcsh:MedicineSocial SciencesNeuroimagingResearch and Analysis MethodsFace RecognitionDiagnostic RadiologyYoung AdultCognitionLearning and MemoryOcular SystemMemoryDiagnostic MedicineFunctional Magnetic Resonance ImagingMedicine and Health SciencesHumansPsychologylcsh:ScienceBrain MappingUnconscious PsychologyRadiology and Imaginglcsh:RCognitive PsychologyBiology and Life SciencesPriming (Psychology)Magnetic Resonance ImagingFaceCognitive ScienceEyeslcsh:QFemalePerceptionSensory PerceptionAccess to ConsciousnessAnatomyHeadResearch ArticleNeurosciencePloS one
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Types of Triggers in Migraine - Factor Structure of the Headache Triggers Sensitivity and Avoidance Questionnaire and Development of a New Short Form…

2020

OBJECTIVE: To examine the factor structure of the Headache Triggers Sensitivity and Avoidance Questionnaire (HTSAQ) and its German version (HTSAQ-G), in order to identify potential different types of triggers. Furthermore, a short form of the questionnaire was developed. BACKGROUND: The HTSAQ includes 24 of the most commonly reported headache triggers (eg, stress, odors, lack of sleep). Both the HTSAQ and HTSAQ-G appeared to be reliable and valid measures of sensitivity to and avoidance of headache triggers. METHODS: In a cross-country collaboration, data from 2 cross-sectional studies including N = 391 individuals diagnosed with migraine from Australia (n = 222) and Germany (n = 169) were …

AdultMaleCoping (psychology)AdolescentPsychometricsMigraine DisordersFactor structure03 medical and health sciencesYoung Adult0302 clinical medicineChronic MigraineCronbach's alphaGermanymedicineHumans030212 general & internal medicineAgedAged 80 and overbusiness.industryCluster headacheAustraliaMiddle Agedmedicine.diseaseConfirmatory factor analysisClinical PracticeCross-Sectional StudiesNeurologyMigraineFemaleNeurology (clinical)businessFactor Analysis Statistical030217 neurology & neurosurgeryClinical psychologyHeadacheReferences
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