Search results for "Healthy subject"

Repeatability Study on a Classifier for Gastric Cancer Detection from Breath Sensor Data

2019

The SNIFFPHONE device is a portable multichannel gas sensor, aiming to detect gastric cancer (GC) from breath samples. It employs gold nanoparticle (GNP) sensors reacting to volatile organic compounds (VOCs) in the exhaled breath, a non-invasive technique to support early diagnosis. This study evaluates the repeatability of the SNIFFPHONE classification result for measurements conducted on healthy subjects over a short period of time of less than 10 minutes. Due to the portable nature of the device, repeatability is studied with respect to varying measurement location. We find the classification results repeatable with a statistically significant 81 % Pearson correlation coefficient, even t…

Use of Caffeine for Cognitive Enhancement

2015

Abstract Pharmacological cognitive enhancement (CE) refers to the use of divergent psychoactive substances with the purpose of enhancing one's own cognition (e.g., increasing vigilance, concentration, memory). The group of substances for CE includes divergent over-the-counter drugs. Caffeine-containing products such as coffee, caffeinated drinks, and caffeine tablets are integral part of this group of substances. Furthermore, prescription drugs as well as illicit drugs belong to this group of CE substances (e.g., [psycho-]stimulants, modafinil). The use of caffeine in normal healthy subjects has very limited procognitive effects. However, there are few procognitive effects in healthy but sl…

Hemodynamic Changes During Physiological and Pharmacological Stress Testing in Healthy Subjects, Aortic Stenosis and Aortic Coarctation Patients–A Sy…

2019

Introduction: Exercise testing has become a diagnostic standard in the evaluation and management of heart disease. While different methods of exercise and pharmacological stress testing exist, only little is known about their comparability. We aimed to assess hemodynamic changes during dynamic exercise, isometric exercise, and dobutamine stress testing at different stress intensities in healthy subjects and patients with aortic stenosis (AS) and aortic coarctation (CoA).Methods: A systematic literature search (PROSPERO 2017:CRD42017078608) in MEDLINE of interventional trials was conducted to identify eligible studies providing evidence of changes in hemodynamic parameters under different st…

Efectos de la vibración sobre la actividad del rectus abdominis y sobre la transmisión de aceleraciones durante la realización de un puente frontal. …

2012

Durante las dos ultimas decadas se ha incrementado notablemente la utilizacion de la vibracion como medio complementario de ejercicio fisico. La literatura cientifica muestra distintos efectos positivos, aunque la mayor parte de ensayos se han centrado en el analisis del ejercicio de squat. El objetivo del presente estudio fue analizar la actividad muscular del rectus abdominis y la transmision de la vibracion en el cuerpo humano durante la realizacion de un puente frontal sobre una plataforma vibratoria oscilante vibrando a diferentes frecuencias (5, 16, 20 Hz) y a una amplitud constante (3 mm). Las aceleraciones maximas en la cabeza (ejes X, Y, Z) y la actividad electromiografica media de…

Effects of a training program on stable vs unstable surfaces on postural stability. [Efectos de un programa de entrenamiento en superficies estables …

2019

The training surface can modulate the body’s response to training stimuli. The purpose of the article was to determine the influence of two types of training programs on stable/unstable surfaces on postural stability. 20 physically active participants with no history of lower limb injuries were randomly assigned to 3 groups (Control, Unstable Training, Stable Training), and performed supervised training in 16 sessions. Dynamic postural stability and static stability were assessed and tests were performed at baseline after completion of the training and 1, 2 and 4 weeks after the training process. The stable surface training group improved dynamic stability between the pre-test and the two f…

Temperature Measurement by Diffusion-Weighted Imaging

2021

Diffusion-weighted imaging (DWI) thermometry is a magnetic resonance-based imaging tool that allows the noninvasive measurement of brain core temperature. Although only applicable to cerebrospinal fluid, it is thought to be potentially useful in assessing the thermal pathophysiology of the brain in both patients and healthy subjects. The objective of this article is to provide a concise but thorough review of the basic physical principles and the principal applications of DWI thermometry as a potential method to elucidate the pathophysiology of several brain diseases and neurologic syndromes.

415 Does angiotensin-converting enzyme I/D polymorphism afect blood pressure and diastolic function? Findings after six years of follow up in healthy…

2003

Soleus and lateral gastrocnemius H-reflexes during standing with unstable footwear

2015

Introduction: Unstable footwear has been shown to increase lower extremity muscle activity, but the reflex response to perturbations induced by this intervention is unknown. Methods: Twenty healthy subjects stood in stable and unstable footwear conditions (presented randomly) while H-reflex amplitude and background muscle activity were measured in the soleus and lateral gastrocnemius (LG) muscles. Results: Wearing unstable footwear resulted in larger H-reflexes (normalized to the maximal M-wave) for the LG (+12%; P = 0.025), but not for the soleus (+4%; P > 0.05). Background activity of both muscles was significantly higher in the unstable condition. Conclusions: The H-reflex facilitation o…

Narcoleptic and schizophrenic hallucinations

2002

The differential diagnosis of narcolepsy versus schizophrenia is sometimes complicated by similar phenomenology, particularly when hallucinations predominate. REM sleep disturbances seem fundamental in the pathophysiology of narcolepsy, and REM sleep intrusions during periods of wakefulness are often associated with hallucinations also in healthy controls and in patients with other brain disorders including schizophrenia. This study used a semistructured interview to investigate different aspects of hallucinations (frequency, modality, content, and dependence on body posture) in 148 patients with narcolepsy, 21 patients with acute exacerbation of a schizophrenic disorder, and 128 healthy su…

High performance liquid chromatography analysis of tear protein patterns in diabetic and non-diabetic dry-eye patients.

2001

To analyze and compare the high performance liquid chromatography (HPLC) runs of tear proteins from diabetic (DIDRY) and non-diabetic (DRY) dry-eye patients, and healthy subjects (CTRL). The patterns were analyzed using multivariate statistical methods.Tears (total 56 eyes: CTRL: n=16, DIDRY: n=21, and DRY: n=19) were analyzed by HPLC, using a size-exclusion column with an eluent of 0.5 M sodium phosphate buffer. The patients were primarily grouped according to the results of the basic secretory test (BST) in combination with subjective symptoms such as burning, foreign body sensations, tearing, and "dryness" of the eyes. Patients with BST valuesor = 10 mm/5 min plus two subjective symptoms…