Search results for "Hesperidin"

showing 10 items of 17 documents

Deficit irrigation and maturation stage influence quality and flavonoid composition of ‘Valencia’ orange fruit

2016

Background: Effects of continuous deficit irrigation (DI) and partial rootzone drying (PRD) treatments (50% ETc) in comparison with full irrigation (CI, 100% ETc) were investigated during 'Valencia' orange fruit maturation. Ultra-high-performance liquid chromatography/high-resolution mass spectrometry was used to quantify hesperidin, narirutin, tangeritin, nobiletin, didymin and neoeriocitrin in the fruit juice and peel.; Results: No significant effect of irrigation was found on yield, juice soluble solids or acidity. Juice color was not influenced by irrigation or harvest date, whereas peel color increased during maturation and was more pronounced in CI and PRD fruits. Juice acidity reache…

0106 biological sciencesIrrigationNutrition and DieteticsNarirutinChemistryDeficit irrigationfood and beverages04 agricultural and veterinary sciencesOrange (colour)01 natural sciencesNobiletinchemistry.chemical_compoundHorticultureHesperidinNeoeriocitrinBotany040103 agronomy & agriculture0401 agriculture forestry and fisheriesPalatabilityAgronomy and Crop Science010606 plant biology & botanyFood ScienceBiotechnologyJournal of the Science of Food and Agriculture
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Huanglongbing modifies quality components and flavonoid content of ‘Valencia’ oranges

2015

BACKGROUND: In order to evaluate the effect of citrus greening disease, or Huanglongbing (HLB), on quality components and flavonoid contents of ‘Valencia’ oranges, fruit from non-infected trees (control), from infected trees but symptom-less (asymptomatic) and from infected trees and showing clear HLB symptoms (symptomatic) were harvested in March and in May, 2013. Fruit peel, pulp and juice were separated, the main quality components were determined, and hesperidin, nobiletin, tangeretin, narirutin and didymin were quantified using liquid chromatography. RESULTS: Peel colour, total soluble solids and citric acid were similar in control and asymptomatic fruits. Symptomatic fruits were small…

0106 biological scienceschemistry.chemical_classificationNutrition and Dieteticsgenetic structuresNarirutin010401 analytical chemistryFlavonoidfood and beveragesBiology01 natural sciencesNobiletin0104 chemical scienceschemistry.chemical_compoundTangeretinHesperidinchemistryCitrus greening diseaseFood scienceCitric acidAgronomy and Crop ScienceCitrus × sinensis010606 plant biology & botanyFood ScienceBiotechnologyJournal of the Science of Food and Agriculture
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Green solvents and Ultrasound-Assisted Extraction of bioactive orange (Citrus sinensis) peel compounds.

2019

AbstractByproducts such as orange peel have potential uses because of their bioactive compounds, which are important for their potential to reduce the risk factors of diseases caused by aging. The lack of effective techniques and the high levels of pollution produced by the conventional extraction of bioactive compounds using organic solvents have highlighted the need to enhance the ‘green chemistry’ trend. This study evaluates the use of ultrasound to extract bioactive compounds from orange peel. The antioxidant capacity, phenolic content, ascorbic acid, total carotenoids, and HPLC profile of phenolic compounds from orange peel extracts were obtained by a physicochemical evaluation. The re…

0301 basic medicineGreen chemistrylcsh:MedicineOrange (colour)Chemical FractionationHigh-performance liquid chromatographyCharacterization and analytical techniquesAntioxidantsArticle03 medical and health sciencesHesperidinchemistry.chemical_compound0404 agricultural biotechnologyPhenolsUltrasonicsFood sciencelcsh:ScienceCarotenoidchemistry.chemical_classification030109 nutrition & dieteticsMultidisciplinaryVitamin CPlant Extractslcsh:RGreen Chemistry Technology04 agricultural and veterinary sciencesAscorbic acid040401 food scienceCarotenoidschemistrySustainabilityFruitlcsh:QCitrus × sinensisCitrus sinensisScientific reports
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Bergamot reduces plasma lipids, atherogenic small dense LDL, and subclinical atherosclerosis in subjects with moderate hypercholesterolemia: A 6 mont…

2016

Background: Some patients experience statin-induced side effects or prefer nutraceutical approaches for the treatment of dyslipidemia. This has led to a search for alternative therapeutic approaches for dyslipidemia management. In recent studies Citrus bergamia (known as Bergamot) juice was able to reduce serum levels of lipids. Such benefit may be attributed to high amounts of flavonoids contained in Bergamot fruit juice (neoeriocitrin, neohesperidin, naringin). The aim of the present study was to fully investigate the effects of a Bergamot extract on cardio-metabolic parameters, including plasma lipids, atherogenic lipoproteins and subclinical atherosclerosis. Methods: Eighty subjects (42…

0301 basic medicinemedicine.medical_specialtyHypercholesterolemiaBergamotCarotid IMT030204 cardiovascular system & hematology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicineNeoeriocitrinMedicinePharmacology (medical)Prospective cohort studyNaringinOriginal ResearchLDL subclassesPharmacologyNeohesperidinbusiness.industryCholesterollcsh:RM1-950medicine.diseaseCardiovascular risklcsh:Therapeutics. Pharmacology030104 developmental biologyEndocrinologychemistryLow-density lipoproteinlipids (amino acids peptides and proteins)LDL subclassebusinessDyslipidemiaLipoprotein
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New neuroprotective effect of lemon integropectin on neuronal cellular model

2021

Lemon IntegroPectin obtained via hydrodynamic cavitation of organic lemon processing waste in water shows significant neuroprotective activity in vitro, as first reported in this study investigating the effects of both lemon IntegroPectin and commercial citrus pectin on cell viability, cell morphology, reactive oxygen species (ROS) production, and mitochondria perturbation induced by treatment of neuronal SH-SY5Y human cells with H2O2. Mediated by ROS, including H2O2 and its derivatives, oxidative stress alters numerous cellular processes, such as mitochondrial regulation and cell signaling, propagating cellular injury that leads to incurable neurodegenerative diseases. These results, and t…

Cell signalingantioxidantPhysiologyhesperidin;Antioxidant Flavonoids Hesperidin Mitochondria Neu-roprotective Neurological disease Oxidative stress PectinClinical BiochemistryRM1-950antioxidant;MitochondrionCell morphologymedicine.disease_causeBiochemistryNeuroprotectionArticleflavonoids;03 medical and health sciences0302 clinical medicinehesperidinmedicineoxidative stressViability assayneurological diseaseMolecular Biology030304 developmental biologychemistry.chemical_classificationpectinoxidative stress;neuroprotective;0303 health sciencesReactive oxygen speciespectin;neuroprotectiveCell BiologyCell biologymitochondriachemistryneurological disease;flavonoidsTherapeutics. PharmacologyCellular model030217 neurology & neurosurgeryOxidative stress
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The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease.

2017

Despite continuous improvement in our knowledge and management of chronic venous disease (CVD), certain areas, such as the role of muscarinic receptors in the pathology and treatment of CVD, remain unexplored. The symposium "The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of CVD", held at the Annual Meeting of the European Venous Forum on 7-9 July 2016 in London, presented an update on the pathophysiology of CVD and highlighted how the combination of Ruscus extract, hesperidin methyl chalcone, and vitamin C (Ruscus/HMC/VitC; Cyclo 3® Fort), may counteract the deleterious processes underlying CVD. The data presented during this symposium are reported …

ChalconeInflammationAscorbic Acid030204 cardiovascular system & hematologyPharmacologyVeins03 medical and health scienceschemistry.chemical_compoundHesperidin0302 clinical medicineChalconesLondonMedicineHumansVascular DiseasesRandomized Controlled Trials as TopicbiologyVitamin Cbusiness.industryPlant ExtractsHesperidinCongresses as Topicbiology.organism_classificationResponse to treatmentPathophysiologyRuscusTreatment OutcomechemistryRuscus030220 oncology & carcinogenesisChronic DiseaseDrug Therapy Combinationmedicine.symptomCardiology and Cardiovascular MedicineVenous diseasebusinessPhytotherapyInternational angiology : a journal of the International Union of Angiology
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Influence of orange cultivar and mandarin postharvest storage on polyphenols, ascorbic acid and antioxidant activity during gastrointestinal digestio…

2017

Polyphenols, ascorbic acid content and antioxidant activity of two sweet oranges (Navel-N and Cara Cara-CC) and mandarin (Clementine-M) as well as their bioaccessibilities were evaluated in pulps and compared to those in fresh juice. Thus, pulps of oranges and mandarins displayed higher hesperidin (HES), narirutin (NAR), total flavonoids (TF), total phenols (TP) and antioxidant activity (AAC) than their corresponding juices. Also, CC products presented higher bioactive compounds content than N ones. Bioaccessibility of bioactive compounds and AAC were higher in pulps of both oranges and mandarin than in their corresponding juices. Oranges (N and CC) pulps and juices presented higher bioacce…

CitrusAntioxidantTotal antioxidant activitymedicine.medical_treatmentIn vitro gastrointestinal digestionCitrus fruitsOrange (colour)Ascorbic Acid01 natural sciencesAntioxidantsAnalytical ChemistryHesperidinchemistry.chemical_compound0404 agricultural biotechnologystomatognathic systemmedicineFood sciencePhenolsFlavonoidsNarirutin010401 analytical chemistryPolyphenols04 agricultural and veterinary sciencesGeneral MedicineAscorbic acid040401 food science0104 chemical scienceschemistryFood StoragePolyphenolFruitPostharvestAscorbic acidOxidation-ReductionFood ScienceFood chemistry
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Flavonoids in Lemon and Grapefruit IntegroPectin

2021

Abstract Following the analysis of terpenes present in new lemon and grapefruit “IntegroPectin” pectins obtained via the hydrodynamic cavitation of industrial lemon and grapefruit processing waste, the HPLC‐MS analysis of flavonoid and other phenolic compounds reveals the presence of eriocitrin, naringin, hesperidin and kaempferol typical of the respective citrus fruits. The pectic fibers rich in rhamnogalacturonan‐I regions act as chemical sponges adsorbing and concentrating at their outer surface highly bioactive citrus flavonoids and terpenes. These findings, together with the unique molecular structure of these new whole citrus pectins, provide preliminary insight into the broad‐scope b…

Citrusfood.ingredientPectinFlavonoidcitrus fruitsTerpenepectinschemistry.chemical_compoundHesperidinfoodhydrodynamic cavitationFood scienceQD1-999NaringinIntegroPectinFlavonoidschemistry.chemical_classificationFull Paperfood and beveragesNeurodegenerative DiseasesGeneral ChemistryFull Papersfood_chemistryChemistrychemistryFruitEriocitrinKaempferolCitrus paradisi
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Huanglongbing modifies quality components and flavonoid content of 'Valencia' oranges.

2014

BACKGROUND: In order to evaluate the effect of citrus greening disease, or Huanglongbing (HLB), on quality components and flavonoid contents of 'Valencia' oranges, fruit from non-infected trees (control), from infected trees but symptom-less (asymptomatic) and from infected trees and showing clear HLB symptoms (symptomatic) were harvested in March and in May, 2013. Fruit peel, pulp and juice were separated, the main quality components were determined, and hesperidin, nobiletin, tangeretin, narirutin and didymin were quantified using liquid chromatography. RESULTS: Peel colour, total soluble solids and citric acid were similar in control and asymptomatic fruits. Symptomatic fruits were small…

FlavonoidsBacteriaHesperidinCitrus greeningColorPeel colourNarirutinCitric AcidSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeFruit and Vegetable JuicesFruit pulpFruitJuice yieldNutrition and DieteticHumansFood ScienceCitrus sinensisPlant DiseasesJournal of the science of food and agriculture
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Hesperetin induces melanin production in adult human epidermal melanocytes

2014

One of the major sources of flavonoids for humans are citrus fruits, hesperidin being the predominant flavonoid. Hesperetin (HSP), the aglycon of hesperidin, has been reported to provide health benefits such as antioxidant, anti-inflammatory and anticarcinogenic effects. However, the effect of HSP on skin pigmentation is not clear. Some authors have found that HSP induces melanogenesis in murine B16-F10 melanoma cells, which, if extrapolated to in vivo conditions, might protect skin against photodamage. Since the effect of HSP on normal melanocytes could be different to that observed on melanoma cells, the described effect of HSP on murine melanoma cells has been compared to the effect obta…

Human skinMelanocyteBiologyToxicologyCell LineMelaninMiceHesperidinchemistry.chemical_compoundmedicineAnimalsHumansMelanomaMelaninsMolecular StructureEpidermis (botany)HesperidinMelanomaHesperetinGeneral Medicinemedicine.diseaseMicrophthalmia-associated transcription factorMolecular biologymedicine.anatomical_structureEpidermal CellsBiochemistrychemistryMelanocytesFood ScienceFood and Chemical Toxicology
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