Search results for "Hierarchical"
showing 10 items of 260 documents
Statistically validated hierarchical clustering: Nested partitions in hierarchical trees
2022
We develop an algorithm that is fast and scalable in the detection of a nested partition extracted from a dendrogram that is obtained from hierarchical clustering of a multivariate series. Our algorithm provides a -value for each clade observed in the hierarchical tree. The -value is obtained by computing many bootstrap replicas of the dissimilarity matrix and by performing a statistical test on each difference between the dissimilarity associated with a given clade and the dissimilarity of the clade of its parent node. We prove the efficacy of our algorithm with a set of benchmarks generated by a hierarchically nested factor model. We compare results obtained by our algorithm with those of…
Bayesian hierarchical models in manufacturing bulk service queues
2006
In this paper, Queueing Theory and Bayesian statistical tools are used to analyze the congestion of various manufacturing bulk service queues with the same characteristics that are working independently of one another and in equilibrium. Hierarchical models are discussed in order to develop the whole inferential process for the parameters governing the system. Markov Chain Monte Carlo methods and numerical inversion of transforms are addressed to compute the posterior predictive distributions of the usual measures of performance in practice.
Probabilistic small area risk assessment using GIS-based data: a case study on Finnish childhood diabetes
2000
A Bayesian hierarchical spatial model is constructed to describe the regional incidence of insulin dependent diabetes mellitus (IDDM) among the under 15-year-olds in Finland. The model exploits aggregated pixel-wise locations for both the cases and the population at risk. Typically such data arise from combining geographic information systems (GIS) with large databases. The dates of diagnosis and locations of the cases are observed from 1987 to 1996. The population at risk counts are available for every second year during the same period. A hierarchical model is suggested for the pixel wise case counts, including a population model to account for the uncertainty of the population at risk ov…
Iterative Cluster Analysis of Protein Interaction Data
2004
Abstract Motivation: Generation of fast tools of hierarchical clustering to be applied when distances among elements of a set are constrained, causing frequent distance ties, as happens in protein interaction data. Results: We present in this work the program UVCLUSTER, that iteratively explores distance datasets using hierarchical clustering. Once the user selects a group of proteins, UVCLUSTER converts the set of primary distances among them (i.e. the minimum number of steps, or interactions, required to connect two proteins) into secondary distances that measure the strength of the connection between each pair of proteins when the interactions for all the proteins in the group are consid…
Bayesian Design of “Successful” Replications
2002
Replication of experiments is commonin applied research. However, systematic studies of the goals and motivations of a “replication” are rare. As a consequence, there does not seem to be a precise notion of what a “success” when replicating means. This article discusses some of the possible goals for replication; this leads to different (but precise) notions of “success” when replicating. Bayesian hierarchical models allow for a flexible and explicit incorporation of the assumed relationship among the experiments. Bayesian predictive distributions are a natural tool to compute the probability of the replication being successful, and hence to design the replication so that the probability of…
Preventing Overlaps in Agglomerative Hierarchical Conceptual Clustering
2020
Hierarchical Clustering is an unsupervised learning task, whi-ch seeks to build a set of clusters ordered by the inclusion relation. It is usually assumed that the result is a tree-like structure with no overlapping clusters, i.e., where clusters are either disjoint or nested. In Hierarchical Conceptual Clustering (HCC), each cluster is provided with a conceptual description which belongs to a predefined set called the pattern language. Depending on the application domain, the elements in the pattern language can be of different nature: logical formulas, graphs, tests on the attributes, etc. In this paper, we tackle the issue of overlapping concepts in the agglomerative approach of HCC. We …
An AI Walk from Pharmacokinetics to Marketing
2009
This work is intended for providing a review of reallife practical applications of Artificial Intelligence (AI) methods. We focus on the use of Machine Learning (ML) methods applied to rather real problems than synthetic problems with standard and controlled environment. In particular, we will describe the following problems in next sections: • Optimization of Erythropoietin (EPO) dosages in anaemic patients undergoing Chronic Renal Failure (CRF). • Optimization of a recommender system for citizen web portal users. • Optimization of a marketing campaign. The choice of these problems is due to their relevance and their heterogeneity. This heterogeneity shows the capabilities and versatility …
Interfacial Self-Assembly to Spatially Organize Graphene Oxide Into Hierarchical and Bioactive Structures
2020
Multicomponent self-assembly holds great promise for the generation of complex and functional biomaterials with hierarchical microstructure. Here, we describe the use of supramolecular co-assembly between an elastin-like recombinamer (ELR5) and a peptide amphiphile (PA) to organize graphene oxide (GO) flakes into bioactive structures across multiple scales. The process takes advantage of a reaction—diffusion mechanism to enable the incorporation and spatial organization of GO within multiple ELR5/PA layers. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ImageJ software were used to demonstrate the hierarchical organization of GO flakes within the ELR5/PA lay…
The Hierarchical Continuous Pursuit Learning Automation: A Novel Scheme for Environments With Large Numbers of Actions.
2019
Although the field of learning automata (LA) has made significant progress in the past four decades, the LA-based methods to tackle problems involving environments with a large number of actions is, in reality, relatively unresolved. The extension of the traditional LA to problems within this domain cannot be easily established when the number of actions is very large. This is because the dimensionality of the action probability vector is correspondingly large, and so, most components of the vector will soon have values that are smaller than the machine accuracy permits, implying that they will never be chosen . This paper presents a solution that extends the continuous pursuit paradigm to …
The Hierarchical Continuous Pursuit Learning Automation for Large Numbers of Actions
2018
Part 10: Learning - Intelligence; International audience; Although the field of Learning Automata (LA) has made significant progress in the last four decades, the LA-based methods to tackle problems involving environments with a large number of actions are, in reality, relatively unresolved. The extension of the traditional LA (fixed structure, variable structure, discretized, and pursuit) to problems within this domain cannot be easily established when the number of actions is very large. This is because the dimensionality of the action probability vector is correspondingly large, and consequently, most components of the vector will, after a relatively short time, have values that are smal…