Search results for "High Pressure"

showing 10 items of 894 documents

Determination of non-ionic and anionic surfactants in industrial products by separation on a weak ion-exchanger, derivatization and liquid chromatogr…

2013

Abstract A method for the determination of priority surfactants, including fatty alcohol ethoxylates (FAE), alkylether sulfates (AES) and linear alkylbenzene sulfonates (LAS) is described. The samples were diluted with 50% methanol at pH 4 prior to solid-phase extraction on a weak anionic exchanger (WAX). The AES and LAS surfactant classes were retained, whereas the non-ionic components, including most FAE oligomers were eluted. After washing the WAX cartridge to remove cations, the remaining hydrophobic FAE oligomers were eluted using hot 80% methanol at pH 4 (at ca. 50 °C). These two eluates were combined to constitute the non-ionic fraction. Then, AES and LAS were eluted using 80% MeOH w…

AnionsWaxPhthalic anhydrideChromatographyEsterificationLinear alkylbenzeneElutionOrganic ChemistryExtraction (chemistry)Fatty alcoholGeneral MedicineHydrogen-Ion ConcentrationChromatography Ion ExchangeBiochemistryAnalytical ChemistrySurface-Active Agentschemistry.chemical_compoundchemistryvisual_artvisual_art.visual_art_mediumMethanolDerivatizationChromatography High Pressure LiquidJournal of Chromatography A
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In Vitro Bioavailability of Phenolic Compounds from Five Cultivars of Frozen Sweet Cherries (Prunus aviumL.)

2008

The bioavailability of phenolic compounds from five cultivars of frozen sweet cherries was assessed by a digestion process involving pepsin-HCl digestion (to simulate gastric digestion) and pancreatin digestion with bile salts (to simulate small intestine conditions) and dialyzed to assess serum- and colon-available fractions. After pepsin digestion, the % recovery of total phenolics, relative to the original starting material, increased, whereas the % anthocyanins did not change. Following pancreatic digestion and dialysis, the total phenolics in the IN (serum-available) fraction was about 26–30% and the OUT (colon-available) fraction was about 77–101%. The anthocyanin content in the IN fr…

AnthocyaninBiological AvailabilityFraction (chemistry)In Vitro TechniquescianydinAnthocyaninsfunctional food digestionchemistry.chemical_compoundPrunuscherryPhenolsSpecies SpecificitySettore BIO/10 - BiochimicaFreezingflavonoids total phenolicmedicineCultivarFood scienceChromatography High Pressure Liquidfood and beveragesGeneral ChemistryPepsin AIn vitroSmall intestineBioavailabilitySettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboreemedicine.anatomical_structurechemistryBiochemistryFruitAnthocyaninDigestionHydrochloric AcidPrunusbioavailabilitymaturityGeneral Agricultural and Biological SciencesDigestionripening.Journal of Agricultural and Food Chemistry
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Polyaspartylhydrazide Copolymer-Based Supramolecular Vesicular Aggregates as Delivery Devices for Anticancer Drugs

2008

In this paper we report on three different hydrophilic copolymers based on alpha,beta-polyaspartylhydrazide (PAHy) bearing butyric groups in the side chain (C 4) (PAHy-C 4) or a combination of butyric groups and positive charged residues ((carboxypropyl)trimethylammonium chloride, CPTACl) (PAHy-C 4-CPTA) that were synthesized and used for the preparation of new supramolecular vesicular aggregates (SVAs) containing gemcitabine as an antitumor drug. Gemcitabine-loaded SVAs containing synthesized PAHy derivatives were characterized from the physicochemical and technological point of view and the in vitro toxicity and anticancer activity on two different human cancer cell lines, i.e., CaCo-2 (h…

Antimetabolites AntineoplasticMagnetic Resonance SpectroscopyPolymers and PlasticsPolymerssupramolecular aggregates polyaspartylhydrazide copolymersSupramolecular chemistryApoptosisBioengineeringDeoxycytidineBiomaterialsButyric acidchemistry.chemical_compoundDrug Delivery SystemsTumor Cells CulturedMaterials ChemistrySide chainCopolymerHumansThyroid NeoplasmsCytotoxicityCells CulturedChromatography High Pressure LiquidDrug CarriersMolecular StructureChemistryVesicleFlow CytometryGemcitabineIn vitroBiochemistryColonic NeoplasmsChromatography GelPeptidesDrug carrierBiomacromolecules
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Evaluation of quality changes of blueberry juice during refrigerated storage after high-pressure and pulsed electric fields processing

2012

Abstract A better knowledge of the effect of refrigerated storage on the nutritional and physicochemical characteristics of foods processed by emerging technologies with regard to unprocessed juices is necessary. Thus, blueberry juice was processed by high pressure (HP) (600 MPa/42 °C/5 min) and pulsed electric fields (PEF) (36 kV/cm, 100 μs). The stability of physicochemical parameters, antioxidant compounds (ascorbic acid, total phenolics, total anthocyanins) and antioxidant capacity was studied just after treatment and during 56 days at refrigerated storage at 4 °C. Just after treatment, all treated blueberry juices showed a decrease lower than 5% in ascorbic acid content compared with t…

AntioxidantChemistrymedicine.medical_treatmentGeneral ChemistryAscorbic acidIndustrial and Manufacturing EngineeringAntioxidant capacityColor changesHigh pressuremedicineFood scienceAfter treatmentFood ScienceConservation treatmentInnovative Food Science & Emerging Technologies
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Comparative analysis of radical scavenging and antioxidant activity of phenolic compounds present in everyday use spice plants by means of spectropho…

2010

Comparative analysis of radical scavenging and antioxidant activities of phenolic compounds present in everyday use spice plants was carried out by means of spectrophotometric and chromatographic methods. Six spice plant samples, namely onion (Allium cepa), parsley (Petroselinum crispum) roots and leaves, celery (Apium graveolens) roots and leaves and leaves of dill (Anethum graveolens) were analyzed. Total amount of phenolic compounds and radical scavenging activity (RSA) was the highest in celery leaves and dill extracts and was the lowest in celery roots. Comparing commonly used spectrophotometric analysis of 2,2-diphenyl-1-picrylhydrazyl (DPPH) RSA of extracts with the results obtained …

AntioxidantDPPHmedicine.medical_treatmentFiltration and SeparationPharmacognosyPlant RootsHigh-performance liquid chromatographyAntioxidantsAnalytical Chemistrychemistry.chemical_compoundPhenolsOnionsElectrochemistrymedicinePhenolsSpicesChromatography High Pressure LiquidApiumChromatographybiologyChemistryAnethum graveolensApium graveolensFree Radical Scavengersbiology.organism_classificationPlant LeavesAlliumPetroselinumAnethum graveolensJournal of Separation Science
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Phytochemical profile and antioxidative properties of Plinia trunciflora fruits: A new source of nutraceuticals.

2020

Abstract This study evaluated the polyphenol profile and the antioxidative properties of Plinia trunciflora (O. Berg) Kausel fruits. Folin-Ciocalteau and pH-jumping methods indicated that these berries are a major source of antioxidant polyphenols (1201.05 mg GAE/100 g FW), particularly anthocyanins. HPLC-DAD-ESI-MS/MS analysis identified cyanidine glycosides as the main components. Flavon-3-ols and hydrolysable-tannins were also found. CAA assay showed that extracts of P. trunciflora fruits prevent lipid peroxidation in HepG2 cells with higher efficacy than other colourful fruits (CAA50 935.25 mg FW/mL cell medium). Moreover, our results suggested that the observed antioxidant protection i…

AntioxidantDPPHmedicine.medical_treatmentMyrtaceaePhytochemicals01 natural sciencesAntioxidantsAnalytical ChemistryAnthocyaninsLipid peroxidationchemistry.chemical_compoundTandem Mass SpectrometrySettore BIO/10 - BiochimicaFood scienceChromatography High Pressure LiquidChromatographyABTSbiologyChemistryfood and beverages04 agricultural and veterinary sciencesGeneral MedicineHep G2 CellsJaboticaba040401 food scienceUp-RegulationPhytochemicalHigh Pressure LiquidAntioxidant enzymesMyrciaria truncifloraPlinia0404 agricultural biotechnologyNutraceuticalmedicineHumansGlutathione PeroxidasePlant ExtractsSuperoxide DismutaseAntioxidant enzyme010401 analytical chemistryPolyphenolsbiology.organism_classification0104 chemical sciencesPolyphenolFruitDietary SupplementsLipid PeroxidationAnthocyanins; Antioxidant enzymes; Cellular antioxidant activity (CAA); Jaboticaba; Myrciaria trunciflora; Antioxidants; Chromatography High Pressure Liquid; Dietary Supplements; Fruit; Glutathione Peroxidase; Hep G2 Cells; Humans; Lipid Peroxidation; Myrtaceae; Phytochemicals; Plant Extracts; Polyphenols; Superoxide Dismutase; Tandem Mass Spectrometry; Up-RegulationCellular antioxidant activity (CAA)Food ScienceFood chemistry
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Antioxidant Activity of All-trans-retinol in Homogeneous Solution and in Phosphatidylcholine Liposomes

1993

A kinetic quantification of the lipoperoxyl radical-scavenging activity of all-trans-retinol has been carried out in homogeneous solution, when radicals were produced from the oxidation of methyl linoleate in methanol, initiated by the lipid-soluble 2,2′-azobis (2,4-dimethyl-valeronitrile) (AMVN) as well as in a soybean phosphatidylcholine membrane model, in which peroxidation was induced either by AMVN or the hydrophylic 2,2′-azobis(2-amidinopropane)hydrochloride (AAPH). The physical microenvironment contributes to the determination of antioxidant efficiency of all-trans-retinol. In homogeneous solution the kinetic constant kinh is 3.5 × 105 M-1 s-1 and appears of the same order of magnitu…

AntioxidantFree Radicalsmedicine.medical_treatmentRadicalLipid BilayersAmidinesBiophysicsSynthetic membranealpha tocopherolTritiumBiochemistryphosphatidylcholine: retinolchemistry.chemical_compoundPhosphatidylcholineNitrilesmedicineOrganic chemistryAll trans retinolVitamin ALipid bilayerMolecular BiologyChromatography High Pressure LiquidLiposomeBilayerFree Radical ScavengersOxidantsSolutionsKineticschemistryliposomeLiposomesPhosphatidylcholinesBiophysicsLipid PeroxidationAzo CompoundsArchives of Biochemistry and Biophysics
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Polyphenols pattern and correlation with antioxidant activities of berries extracts from four different populations of SicilianSambucus nigraL.

2014

Sambucus nigra L. (Caprifoliaceae) is wide spread in temperate and sub-tropical zones. The consumption of its berries has been associated with health benefits especially for its high content of natural antioxidants such as polyphenols, in particular anthocyanins. In this work we investigated the polyphenolic composition and the in vitro antioxidant activities (ABTS, DPPH, BCB and FRAP-ferrozine (FRAP-FZ) assays) of S. nigra berries, collected in four different Sicilian areas (Italy). Elderberries are considered one of the fruits with highest anthocyanins content, the amount of phenolic compounds, other than anthocyanins, is approximately 1.5 times greater than the latter. The LC–MS analyses…

AntioxidantSettore AGR/05 - Assestamento Forestale E SelvicolturaDPPHmedicine.medical_treatmentantioxidant activityPlant ScienceSambucus nigraBiochemistryAntioxidantsAnalytical ChemistryAnthocyaninschemistry.chemical_compoundSambucus nigrapolyphenolic compositionBotanymedicineSambucus nigra berries polyphenolic composition antioxidant activitySettore BIO/15 - Biologia FarmaceuticaFood scienceCaprifoliaceaeChromatography High Pressure LiquidABTSMolecular StructurebiologyChemistryOrganic ChemistryPolyphenolsSettore CHIM/06 - Chimica Organicabiology.organism_classificationlanguage.human_languageItalySambucusPolyphenolFruitlanguageComposition (visual arts)Oxidation-ReductionSicilianberrieNatural Product Research
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Extraction of polyphenols in Himanthalia elongata and determination by high performance liquid chromatography with diode array detector prior to its …

2016

Abstract Several studies have demonstrated the antioxidant capacity of seaweeds, which can be used for the development of biopharmaceuticals with extensive medical application. Antioxidant therapies appear to attenuate the organic deterioration originated by an excessive oxidative stress, which could prevent the harmful effects of various injuries such as ischemia-reperfusion (I/R) among others. Marine brown seaweeds play a significant role, as they are the only organisms on earth producing phlorotannins, which are polyphenols that exhibit important biological activity. To ensure obtaining an extract with the greatest antioxidant activity, some variables that affect the extraction of polyph…

AntioxidantTime Factorsmedicine.medical_treatmentClinical BiochemistryPhaeophytaBiochemistryAntioxidantsAnalytical Chemistrychemistry.chemical_compound0404 agricultural biotechnologyChlorogenic acidLimit of DetectionmedicineCaffeic acidGallic acidGentisic acidChromatography High Pressure LiquidChromatography Reverse-PhaseChromatographyTemperaturefood and beveragesPolyphenolsReproducibility of ResultsCatechin04 agricultural and veterinary sciencesCell BiologyGeneral MedicineFree Radical ScavengersSeaweed040401 food scienceOxidative StresschemistryPolyphenolCalibrationMyricetinJournal of chromatography. B, Analytical technologies in the biomedical and life sciences
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Ultrasonically-Assisted and Conventional Extraction from Erodium Glaucophyllum Roots Using Ethanol:Water Mixtures: Phenolic Characterization, Antioxi…

2020

The paper presents experimental results concerning the ultrasonically-assisted extraction of bioactive compounds from Erodium glaucophyllum roots. A comparison with conventional methodology is presented, and thereby the phytochemical composition and the antioxidant and anti-inflammatory activities of extracts are evaluated. The phenolic profile of Erodium extracts was analyzed by TOF&ndash

Antioxidantantioxidantmedicine.medical_treatmentAnti-Inflammatory AgentsPharmaceutical Science02 engineering and technologyPlant RootsAntioxidantsAnalytical Chemistrychemistry.chemical_compoundDrug DiscoverySolid phase extractionCarotenoidChromatography High Pressure Liquidanti-inflammatorychemistry.chemical_classificationbiologyChemistryultrasound04 agricultural and veterinary sciences021001 nanoscience & nanotechnology040401 food scienceUltrasonic WavesChemistry (miscellaneous)Molecular MedicineAntioxidant0210 nano-technologysolid-liquid extractionErodiumPolyphenolTECNOLOGIA DE ALIMENTOSmedicine.drug_classAnti-inflammatoryArticlelcsh:QD241-4410404 agricultural biotechnologylcsh:Organic chemistryPhenolsUltrasoundmedicinePhysical and Theoretical ChemistryChromatographyEthanolPlant ExtractsOrganic ChemistryExtraction (chemistry)Solid-liquid extractionbiology.organism_classificationpolyphenolTracheophytaPolyphenolSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationTroloxAnti-inflammatoryChromatography LiquidMolecules
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