Search results for "Hip"
showing 10 items of 9327 documents
Establishing a New ECMO Referral Center Using an ICU-Based Approach: A Feasibility and Safety Study
2022
Background: A high-volume center with a multidisciplinary team is regarded as the optimal place for providing extracorporeal membrane oxygenation (ECMO). We hypothesize that an ECMO center can also be successfully created and subsequently developed entirely by intensivists in a mid-size mixed intensive care unit (ICU). Methods: A model was created for setting up a new ECMO referral center within the structure of an existing mixed ICU in a tertiary hospital. A retrospective analysis was carried out of the first 33 patients treated in the initial period of the center’s activity, from mid 2018 to the end of 2020. Results: An ECMO center was established and developed entirely based on the resou…
Comany establishment and Entrepreneurship Presentations Teoria
2020
Presentacions de l'assignatura Emprenedoria i Creació d'empreses, codi 35822, del Grau en ADE i Doble Grau en Turisme-ADE. Presentations to be employed in the lectures of the subject company establishment and entrepreneurship, code 35822. Degree in business administration and, double Degree in tourism and business administration.
Forming ideal public-private partnerships for export practices : case exporting Resource Wisdom
2017
Vaikuttavien julkisen ja yksityisen sektorin vientikumppanuuksien muodostaminen : tapaustutkimus: Resurssiviisaus vientituotteeksi. Väestönkasvu ja urbanisaatio luovat kestävyyshaasteita, mutta myös mahdollistavat uuden liiketoiminnan ja kestävän kehityksen esiinmarssia. Tämä Pro gradu –tutkielma tarkastelee, miten kestävän aluekehityksen mallia, Resurssiviisautta, voidaan hyödyntää suomalaisten yritysten vientitukena julkisen ja yksityisen sektorin yhteistyöllä. Tutkimus keskittyy tämän yhteistyön muodostamiseen, sen johtamiseen ja ohjaamiseen kuin myös oikeaoppiseen yhteistyön hallinnointiin. Näitä aspekteja tarkastellaan etenkin kaupallisessa vientitarkoituksessa. Pro gradua varten haast…
Les outils d'intelligence territoriale pour les acteurs de terrain à Seraing: entre appropriation des méthodes et acquisition de compétences
2005
Asbl Optim@ leads an experience of participative observation in Seraing since 1998. The complexity of the problems met by the population and the professional division into sectors justified this participative approach. This one concerns the economic, social and human global nature of the territory. It leans on a wide partnership of local actors: professionals, inhabitants and decision-makers. It uses at this end the method of territorial intelligence CATALYSE created by the research team ThéMA-MTI and developed with numerous members of the REIT. The results obtained in terms of interdisciplinary dialogue between inhabitants, professionals and decision-makers; allow identifying axes about th…
CA3–CA1 long‐term potentiation occurs regardless of respiration and cardiac cycle phases in urethane‐anesthetized rats
2023
Breathing and heartbeat synchronize to each other and to brain function and affect cognition in humans. However, it is not clear how cardiorespiratory rhythms modulate such basic processes as synaptic plasticity thought to underlie learning. Thus, we studied if respiration and cardiac cycle phases at burst stimulation onset affect hippocampal long-term potentiation (LTP) in the CA3–CA1 synapse in urethane-anesthetized adult male Sprague–Dawley rats. In a between-subjects design, we timed burst stimulation of the ventral hippocampal commissure (vHC) to systole or diastole either during expiration or inspiration and recorded responses throughout the hippocampus with a linear probe. As classic…
Bibendum semper vivat !
2012
International audience
Protein levels of brain-derived neurotrophic factor in the hippocampus of low/high aerobic capacity rats
2010
Hippocrates and Plato have first documented the connection between a healthy mind and body, during a period which launched analytical thinking and philosophy in Ancient Greece. Modern research has also indicated the contribution of an active lifestyle to enhanced brain performance and decreased incidence of neurodegenerative diseases and mood disorders such as Alzheimer’s disease and depression respectively. This has been hypothesized to emerge through mechanisms which are enhanced by exercise and contribute on brain plas-ticity and health. The Neurotrophins hypothesis implicates several molecules in brain plasticity and healthy aging. Among them, Brain-derived Neurotrophic Factor (BDNF) ha…
Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety
2019
σ1 and/or σ2 receptors play a crucial role in pathological conditions such as pain, neurodegenerative disorders, and cancer. A set of spirocyclic cyclohexanes with diverse O-heterocycles and amino moieties (general structure III) was prepared and pharmacologically evaluated. In structure-activity relationships studies, the σ1 receptor affinity and σ1:σ2 selectivity were correlated with the stereochemistry, the kind and substitution pattern of the O-heterocycle, and the substituents at the exocyclic amino moiety. cis-configured 2-benzopyran cis-11b bearing a methoxy group and a tertiary cyclohexylmethylamino moiety showed the highest σ1 affinity ( Ki = 1.9 nM) of this series of compounds. In…
Performance Management in Local Government: The Application of System Dynamics to Promote Data Use
2014
The purpose of this article is to demonstrate how system dynamics can be used to enrich performance management in local government, focusing specifically on how the development of conceptual and simulation system dynamic models can foster a shared view of the relevant system among stakeholders to overcome factors that limit data use. Responding to this purpose, we present a normative case study on how key drivers can be used to foster a shared view of the residential refuse collection system for supporting policy and process changes. A major finding from our research, however, is that performance management cannot overlook the broader forces of citizenship outcomes that impact the community.
Business model scaling and growth hacking in digital entrepreneurship
2023
Creating an innovative product and validating an innovative business model may not be enough for digital startups to be competitive. To grow fast and expand globally, digital startups need to innovate their business model during the scaling phase. A pragmatic approach has recently been proposed to support digital entrepreneurs engaging in business-model innovation during the scaling phase (i.e., business-model scaling), a strategy known as growth hacking. However, we know little about its theoretical grounding and how effective growth hacking is, as businesses lack methodologies to assess its effectiveness before committing resources and investments. To fill this gap, we developed a method …