Search results for "History and Philosophy of Science"
showing 10 items of 756 documents
Social factors associated with nitrogen dioxide (NO2) exposure during pregnancy: The INMA-Valencia project in Spain
2011
Numerous studies have focused on the effects of exposure to air pollution on health: however, certain subsets of the population tend to be more exposed to such pollutants depending on their social or demographic characteristics. In addition, exposure to toxicants during pregnancy may play a deleterious role in fetal development as fetuses are especially vulnerable to external insults. The present study was carried out within the framework of the INMA (Infancia y Medio Ambiente or Childhood and the Environment) multicenter cohort study with the objective of identifying the social, demographic, and lifestyle factors associated with nitrogen dioxide (NO2) exposure in the subjects in the cohort…
The road to equitable healthcare: A conceptual model developed from a qualitative study of Syrian refugees in Norway
2021
Background Refugees in high-income countries face barriers to healthcare access even when they have the same rights and entitlements as the host population. Disadvantages in healthcare access contribute to differences in health outcomes and impact acculturation. This study explores perceived changes in health status and experiences with the Norwegian healthcare system of Syrian refugees living in Norway, using a trajectory perspective. Methods We conducted 15 semi-structured interviews in April 2020 among purposefully recruited adult refugees from Syria resettled in Norway. Interviews were carried out in Arabic and analysed with Systematic Text Condensation using NVivo software. We used Lév…
Breast Cancer Incidence in Palermo City (Italy)
1996
CCR5 Receptor: Biologic and Genetic Implications in Age-Related Diseases
2007
The CC chemokine receptor 5 (CCR5) is a member of CC-chemokine receptor family. CCR5 has the characteristic structure of a seven transmembrane G protein-coupled receptor (GPCR), which regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands are important molecules in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Recent evidence has also demonstrated the role of CCR5 in a variety of human diseases, ranging from infectious and inflammatory diseases to cancer. In this article, we describe the involvement of CCR5 in two age…
Cellular Distribution and Expression of Cortical Acetylcholine Receptors in Aging and Alzheimer's Disease
1991
Ligand binding studies show marked reductions of nicotinic, but not of muscarinic binding sites in Alzheimer's disease. Using monoclonal antibodies we studied immunohistochemically the expression of the respective receptor proteins in the frontal cortex of middle-aged (55 +/- 5 yr) controls, age-matched controls (73 +/- 6 yr), and patients with Alzheimer's disease (74 +/- 5 yr). Density of nicotinic cholinoceptive neurons was 8000/mm3 for middle-aged controls and 4000/mm3 for age-matched controls, but only 900/mm3 in Alzheimer's brains (p less than 0.0001). Densities of muscarinic cholinoceptive and of Nissl-stained neurons were not significantly different between the groups, pointing to a …
On P-compatible hybrid identities and hyperidentities
1994
P-compatible identities are built up from terms with a special structure. We investigate a variety defined by a set ofP-compatible hybrid identities and answer the question whether a variety defined by a set ofP-compatible hyperidentities can be solid.
Topology, Matter, and Space, I: Topological Notions in 19th-Century Natural Philosophy
1998
L'A. montre l'impact de la topologie dans le developpement de la theorie dynamique des phenomenes physiques ainsi que les speculations de la structure topologique de l'espace
Apolipoprotein E polymorphism is associated with both senile plaque load and Alzheimer-type neurofibrillary tangle formation.
1996
Recent work provided evidence that the apolipoprotein (apo) E polymorphism is associated with late-onset sporadic Alzheimer's disease. The major histological hallmarks of Alzheimer's disease are the extraneuronal deposition of A4/beta-amyloid and the intraneuronal formation of neurofibrillary tangles, the latter correlating strongly with the psychometric status. We examined the relationship between the apo E polymorphism and Alzheimer's disease-related histological changes using a staging system which accounts for the progression of the disease over time and correlates well with the cognitive decline ante mortem. We observed a significant positive correlation between both neurofibrillary ch…
Vincenzo Vincenzi, “Geometer and Engineer to Cardinal Borja”
2017
This paper analyses the figure of Vincenzo Vincenzi on the basis of documents that place him in Valencia in 1635 as engineer and geometer to Cardinal Gaspar de Borja y Velasco. Vincenzi, who was born in the Urbino region, worked as a hydraulic engineer at the Villa d’Este in Tivoli. In Rome he made his name as the inventor of the wind gun and the mobile fountain, inventions that were disseminated through the works of Benedetto Castelli and, above all, those of Giovanni Faber who also served as an intermediary, recommending Vincenzi’s services to cardinals such as Emmanuele Pio di Savoia and taking it upon himself to find buyers for the wind gun. Vincenzi worked for the Bentivoglios on the b…
On john maynard keynes's anti-semitism once again: A documentary note
2015
This note presents new archival evidence about John Maynard Keynes' attitudes toward Jews. The relevant material is composed of two letters sent by Robert G. Wertheimer to Bertrand Russell and Richard F. Kahn along with their replies. Between 1963 and 1964, Wertheimer - An Austrian-born Jewish immigrant then professor of economics at Babson College - wrote to Russell and Kahn asking for their personal reminiscences concerning Keynes' anti-Semitic utterances. In their brief but still significant responses, both Russell and Kahn firmly denied any hint of anti-Semitism in Keynes, thereby providing significant first-hand testimonies from two of his closest acquaintances.