Search results for "Host"
showing 10 items of 1982 documents
Blood Vessel Detection Algorithm for Tissue Engineering and Quantitative Histology.
2021
AbstractImmunohistochemistry for vascular network analysis plays a fundamental role in basic science, translational research and clinical practice. However, identifying vascularization in histological tissue images is time consuming and markedly depends on the operator’s experience. In this study, we present “blood vessel detection—BVD”, an automatic algorithm for quantitative analysis of blood vessels in immunohistochemical images. BVD is based on extraction and analysis of low-level image features and spatial filtering techniques, which do not require a training phase. BVD algorithm performance was comparatively evaluated on histological sections from three different in vivo experiments. …
In viaggio con Stravinsky. Una suite in cinque movimenti (Prefazione di Marcello Panni)
2017
Il volume affronta certi aspetti dell'attività di Igor Stravinsky negli anni Sessanta, sviluppando un percorso articolato in cinque movimenti: "Nice Kids": è il modo in cui Stravinsky definisce John e Jacqueline Kennedy dopo averli incontrati alla Casa Bianca il 18 gennaio 1962, in una serata in cui s’intrecciano mondanità e politica. "Totalitarismi": mentre la critica sovietica lo accusa di essere un cosmopolita decadente e borghese, certi esponenti del nazismo descrivono Stravinsky come un tipico esponente del “bolscevismo culturale”. Il viaggio di Stravinsky in America nel 1939, si trasforma dunque in una nuova tappa del suo esilio. "Mosca e Leningrado": nel 1962 Stravinsky festeggia il …
Vizio di firma. Plagio e dintorni
2022
Se esiste il dono della scrittura, c’è anche chi invidia quel talento e i suoi frutti: un sentimento che può trasformarsi in tentazione, magari portare al furto, perfino all’omicidio. Quante trame ci parlano di questa semplice idea: qualcuno mette il suo nome sull’opera di un altro. Romanzi e film mescolano più o meno gli stessi ingredienti, dosandoli però in modo differente. E chi li osserva può cedere alla fantasticheria di un unico grande racconto del plagio, un tema che fatalmente si ripete perché non si esce dall’ossessione che lo nutre. Una narrazione che lettori e spettatori ritroveranno in questo libro, scandita nelle sale di una lunga galleria. Siamo nel confortevole territorio del…
Phosphatidylserine liposomes reduce inflammatory response, mycobacterial viability and HIV replication in coinfected human macrophages
2021
AbstractChronic immune activation is the key pathogenetic event of Mycobacterium tuberculosis-human immunodeficiency virus (HIV) coinfection. We assessed the therapeutic value of phosphatidylserine-liposome (PS-L) in an in vitro model of M. tuberculosis-HIV coinfection. PS-L reduced nuclear factor-κB activation and the downstream production of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and IL-6 in bacille Calmette-Guérin-infected macrophages and of TNF-α and IL-1β in M. tuberculosis-infected and M. tuberculosis-HIV–coinfected macrophages. Importantly, a significant reduction of intracellular M. tuberculosis viability and HIV replication were also observed. These results suppor…
Phylodynamic Analysis and Implication of HCV Genotype 4 Variability on Antiviral Drug Response and T-Cell Recognition.
2020
Therapies for HCV care could change the prevalence and the geographic distribution of genotypes due to differences in Sustained Virologic Response (SVR). In this scenario, uncommon genotypes/subtypes, such as genotype 4, could spread from high-risk groups, replacing genotypes eradicated by antiviral drugs. Genotype eradication is also strongly influenced by the CD8+ T cell response. In this study, the genetic variability in HCV genotype 4 strains obtained from a cohort of 67 patients naï
Pneumococcal vaccination in celiac disease
2019
Introduction: Celiac disease (CD) is an immune-mediated disorder associated with gluten exposure in genetically predisposed subjects. Areas covered: Infectious disease is one of the causes of morbidity and mortality in CD patients. Invasive streptococcus pneumoniae (pneumococcus) is a particularly dangerous morbid condition in both the general population and celiac patients. Pneumococcal vaccination is the most effective means for its prevention. Expert opinion: In CD, evaluation of spleen function should be useful to select patients who may benefit from vaccination to reduce the risk of pneumococcal disease. Different strategies could be employed: physicians could search for signs of hypos…
Analysis of sterols by high-performance liquid chromatography/mass spectrometry combined with chemometrics
2006
A newly developed high-performance liquid chromatography/mass spectrometry (HPLC/MS) method has been successfully used to analyze plasma concentrations of various phytosterols (cholestanol and beta-sitosterol) and cholesterol metabolites (desmosterol and lathosterol). This was based on an unusual solvent combination of water/methanol vs. methanol/acetone/n-hexane applied on a Purospher Star RP-18e (125 x 2 mm, 3 microm) column, which proved excellent for the separation, identification and quantification of plasma sterols. Simple solid-phase extraction preparation of plasma samples was performed, followed by the developed fast and robust HPLC separation. Results on four groups of people were…
Systematic review: macrophage activation syndrome in inflammatory bowel disease.
2013
Summary Background Recently, there have been increasingly frequent reports on the occurrence of macrophage activation syndrome (MAS) in patients with inflammatory bowel disease (IBD). Clinically, MAS is characterized mainly by fever, hepatosplenomegaly, cytopenia, and elevated circulating ferritin and CD25. Mortality, even if diagnosed rapidly, is high. Aim To identify all reports on MAS in IBD and to establish data on triggering agents, immunosuppression leading to MAS, and mortality. Methods A language unrestricted search on Pubmed and Scopus relating to the past 30 years was carried out by matching the following search-terms: h(a)emophagocytic lymphohistiocytosis OR h(a)emophagocytic lym…
Il cibo come mezzo per una convivenza ostipitale. Gli equilibri fragili del cotto e del crudo fra migranti e popolazione autoctona in un mercato di P…
2021
In questo articolo le ricercatrici riesaminano il concetto di ostipilità (Derrida, 2000) alla luce della cultura materiale, del cibo e delle pratiche alimentari connesse, per analizzare i collegamenti tra cibo, appartenenza e commensalità. L’osservazione partecipante e le interviste semi-strutturate di questa ricerca hanno permesso di segnare i confini del mercato di Ballarò, di individuare le tipologie di attività commerciale, fondate sul “cotto” e/o sul “crudo”, che contraddistinguono le diverse aree di mercato, come pure le forme di “convivenza armata” in atto fra autoctoni e migranti. Se il cibo cotto è ospitale a determinate condizioni, il cibo crudo ha maggiori probabilità di stabilir…
Optical encryption with compressive ghost imaging
2011
Ghost imaging (GI) is a novel technique where the optical information of an object is encoded in the correlation of the intensity fluctuations of a light source. Computational GI (CGI) is a variant of the standard procedure that uses a single bucket detector. Recently, we proposed to use CGI to encrypt and transmit the object information to a remote party [1]. The optical encryption scheme shows compressibility and robustness to eavesdropping attacks. The reconstruction algorithm provides a relative low quality images and requires high acquisitions times. A procedure to overcome such limitations is to combine CGI with compressive sampling (CS), an advanced signal processing theory that expl…