Search results for "HuR"
showing 10 items of 938 documents
Religion as space of enunciation
2014
The principle of communication, which has been present since the origins of religion, can also be seen as its “vanishing point” in the artistic sense: the necessity of relaying, broadcasting, spreading the divine word is such that it is almost as if religion only really exists insofar as it is transmitted, exposed, expressed in some way to a receiver or audience. While this subject has received increased academic interest within the field of communication over recent years, this paper aims to depict certain possible lines of analysis and certain epistemological challenges which are encountered when studying religion. More specifically, it will approach the catholic Church from a socio-semio…
Inventari de l'arxiu parroquial de Nostra Senyora de la Misericòrdia de Campanar
2002
Es descriuen els treballs realitzats per a l'elaboració de l'inventari parroquial de Campanar, el seu context històric, la metodologia utilitzada, una guia breu de l'arxiu, el mateix inventari en funció del quadre de classificació amb les seues sèries conservades, el catàleg dels pergamins i dels llibres de la seua biblioteca, així com la transcripció del pergamí datat en 1460 que es refereix a la firma d'un nou capítol de l'Almoina dels Llauradors de Campanar. It is described the works done to draw up the inventory of the Campanar Church archive (Valencia), its historical context, used methodology, a summary guide of the archive and the own inventory according to the proposed classificatio…
Immunomorphological Patterns of Chaperone System Components in Rare Thyroid Tumors with Promise as Biomarkers for Differential Diagnosis and Providin…
2023
Hurthle cell (HC), anaplastic (AC), and medullary (MC) carcinomas are low frequency thyroid tumors that pose several challenges for physicians and pathologists due to the scarcity of cases, information, and histopathological images, especially in the many areas around the world in which sophisticated molecular and genetic diagnostic facilities are unavailable. It is, therefore, cogent to provide tools for microscopists to achieve accurate diagnosis, such as histopathological images with reliable biomarkers, which can help them to reach a differential diagnosis. We are investigating whether components of the chaperone system (CS), such as the molecular chaperones, can be considered dependabl…
Microstructure and rheological response of laboratory-aged SBS-modified bitumens
2019
Polymer additives are widely used to improve the performance of road bitumens including their resistance to hardening during oxidation, although their oxidative inhibitor effect has not been well documented. This study aims to investigate the effect of laboratory-simulated ageing on the microstructure, and rheological properties of Polymer Modified Bitumens (PMBs) prepared with a Styrene-Butadiene-Styrene (SBS) copolymer and sulphur as a cross-linker. The laboratory ageing was conducted through the Rolling Thin Film Oven (RTFO) and the Pressure Aging Vessel (PAV) procedures. The unaged and aged binders were characterised using the Multiple Stress Creep and Recovery (MSCR) test, Gel Permeati…
IDENTIFICATION OF A CALMODULIN-BINDING SITE WITHIN THE DOMAIN I OF BACILLUS THURINGIENSISCry3Aa TOXIN
2012
Bacillus thuringiensis Cry3Aa toxin is a coleopteran specific toxin highly active against Colorado Potato Beetle (CPB).We have recently shown that Cry3Aa toxin is proteolytically cleaved by CPB midgut membrane associated metalloproteases and that this cleavage is inhibited by ADAM metalloprotease inhibitors. In the present study, we investigated whether the Cry3Aa toxin is a calmodulin (CaM) binding protein, as it is the case of several different ADAM shedding substrates. In pull-down assays using agarose beads conjugated with CaM, we demonstrated that Cry3Aa toxin specifically binds to CaM in a calcium-independent manner. Furthermore, we used gel shift assays and (1)H NMR spectra to demons…
Hemocyanin from the keyhole limpetMegathura crenulata(KLH) carries a novel type of N-glycans with Gal(β1-6)Man-motifs
2002
Keyhole limpet (Megathura crenulata) hemocyanin (KLH), an extracellular respiratory protein, is widely used as hapten carrier and immune stimulant. Although it is generally accepted that the sugar constituents of this glycoprotein are likely to be implicated in the antigenicity and biomedical properties of KLH, knowledge of its carbohydrate structure is still limited. Therefore, we have investigated the N-linked oligosaccharides of KLH. Glycan chains were enzymatically liberated from tryptic glycopeptides, pyridylaminated and separated by two-dimensional HPLC. Only neutral oligosaccharides were obtained and characterized by carbohydrate constituent and methylation analyses, MALDI-TOF-MS, ES…
Controlled cleavage of KLH1 and KLH2 by the V8 protease from Staphylococcus aureus reassociation, electrophoretic and transmission electron microscop…
1999
The reassociation behaviour of protease V8-cleaved peptides from KLH1 and KLH2, the two hemocyanin isoforms from the giant keyhole limpet Megathura crenulata, has been studied by transmission electron microscopy of negatively stained specimens and SDS/PAGE. Reassociation of the complete mixture of protease cleavage products and of combinations of peptide fragments purified by HPLC was performed in the presence of 100 mm CaCl2 and 100 mm MgCl2 at pH 7.4, over a period of 1 to 4 weeks. The V8 protease splits KLH1 into peptide fragments containing the functional units abc, def, defg, defgh, g and h. This mixture of peptide fragments reassociated to form helical tubular polymers, with a diamete…
Biosynthesis of xanthurenic acid 8-O-beta-D-glucoside in Drosophila. Characterization of the xanthurenic acid:UDP-glucosyltransferase activity.
1990
Xanthurenic acid 8-glucoside is a side metabolite of the tryptophan-xanthommatin pathway in Drosophila. From 3-hydroxykynurenine, two biosynthetic pathways can be envisaged, one via xanthurenic acid, and another via 3-O-glucoside of 3-hydroxykynurenine. In this report evidence is presented to show that the synthesis takes place via xanthurenic acid. (a) We have demonstrated that the Drosophila melanogaster vermilion purple mutant (unable to synthesize 3-hydroxykynurenine) synthesizes xanthurenic acid 8-glucoside when fed with xanthurenic acid; and (b) the activities required for its synthesis via xanthurenic acid have been found (3-hydroxykynurenine transaminase and xanthurenic acid:UDP-glu…
Holothuria tubulosa Gmelin 1791 (Holothuroidea, Echinodermata) enhances organic matter recycling in Posidonia oceanica meadows
2014
Abstract The role of Holothuria tubulosa in organic matter recycling of Posidonia oceanica detritus was estimated in a laboratory feeding experiment. The individual mean ingestion rate of seagrass detritus by holothurians was evaluated and carbon and nitrogen stable isotopes, carbon and nitrogen content and C:N ratio analyzed in H. tubulosa , P. oceanica detritus and surface sediment. Results showed that H. tubulosa is capable of ingesting from 30% to 100% of the detritus produced by P. oceanica meadows, depending on the holothurian density. Stable isotope analysis provided evidence for the assimilation of seagrass detritus by H. tubulosa as their signatures were compatible with 1 trophic l…
Chrzest i Eucharystia w nauce Soboru Trydenckiego i współczesnego Katechizmu Kościoła Katolickiego
2017
Artykuł prezentuje problematykę chrztu i Eucharystii przedstawioną w nauce Soboru Trydenckiego i aktualnego Katechizmu Kościoła Katolickiego. Za sprawą reformatorów nauka o chrzcie, a zwłaszcza o ofiarniczym charakterze Eucharystii i realnej obecności Chrystusa pod konsekrowanymi postaciami stała się przedmiotem poważnych kontrowersji, które doprowadziły do tego, że biskupi katoliccy potrafi odnaleźć w Trydencie odwagę, aby dochować wierności Tradycji apostolskiej, co wyrazili w odpowiednich dekretach. Po upływie ponad czterech wieków w Kościele katolickim zrodziła się potrzeba wyraźnych wskazań dotyczących rozumienia prawd wiary. Wielu wiernych miało trudności z jasnym wyrażeniem prawd gło…