Search results for "Hula"
showing 10 items of 41 documents
Disentangling the role of heat and smoke as germination cues in Mediterranean Basin flora
2010
9 páginas, 1 figura, 4 tablas.
The Acheulian Site of Gesher Benot Ya‘aqov
2011
Gesher Benot Ya‘aqov (GBY) is located in the southern Hula Valley, which, in turn, is located in the northernmost segment of the Dead Sea Rift, part of the Great African Rift System. This region is an integral part of the “Levantine Corridor,” a land bridge connecting Africa and Europe, through which the diffusion and biotic exchange of many organisms took place in prehistoric times. The Hula Valley has preserved data of a phenomenon of great importance in human history: archaeological evidence recording hominin diffusion/migration out of Africa and into Eurasia. The unique sedimentological and hydrological conditions prevailing in the Hula, along with extensive and intensive tectonic activ…
Effects of Scrophularia ningpoensis Hemsl. on Inhibition of Proliferation, Apoptosis Induction and NF-κB Signaling of Immortalized and Cancer Cell Li…
2012
Scrophularia ningpoensis has been used in China for centuries as a herbal tea to treat various diseases. Based on the numerous animal studies on its pharmaceutical effects and the long time clinical experiences, we studied the molecular and cellular mechanism underlying the bioactivity of aqueous extract of Scrophularia and its isolated compounds. Seven isolated compounds, unlike Scrophularia extract, failed to induce cytotoxicity on HaCaT cells, but their combination improved the effect of extract. Tumor cell line selectivity was not observed, when we studied its cytotoxic effect on melanoma cell lines. The apoptotic and anti-inflammatory effects of Scrophularia extract have been demonstra…
Phytochemistry and molecular systematics of Triaenophora rupestris and Oreosolen Wattii (Scrophulariaceae)
2008
The relationships between the genera Triaenophora, Oreosolen and Rehmannia were investigated. All three genera were previously included in tribe Veroniceae which was part of Scrophulariaceae but which is now included in Plantaginaceae. With regard to the content of iridoid glucosides, Triaenophora rupestris and the much-investigated Rehmannia were almost identical in containing catalpol, ajugol and 6-feruloylajugol. Oreosolen wattii was rather different in having compounds typical for the tribe Scrophularieae (Scrophulariaceae), namely aucubin, harpagide, harpagoside as well as two diesters of rhamnopyranosylcatalpol, one of which, here named oreosolenoside, had not previously been describe…
Screening of antiinflammatory medicinal plants used in traditional medicine against skin diseases
1998
The antiinflammatory activity of twelve medicinal plants used against skin disorders were tested in different experimental models of topical inflammation and one in vitro inhibitory test against phospholipase A2 (PLA2) from Naja naja venom. Forsythia suspensa was the most active species on the arachidonic acid (AA) topical test. This last species together with Astragalus membranaceus and Ranunculus sceleratus were the most active on the 12-O-tetradecanoylphorbol-13-acetate (TPA) acute ear oedema test. Scrophularia auriculata was the most active on multiple topical applications of TPA and on the oxazolone-induced delayed type hypersensitivity (DTH). Santolina chamaecyparissus was the only sp…
SOIL CHARACTERISTICS, MINERAL NUTRIENTS, BIOMASS, AND CARDENOLIDE PRODUCTION INDIGITALIS OBSCURAWILD POPULATIONS
2002
Mature leaves of wild-growing Digitalis obscura plants and soil samples were collected in four different regions. Soil and leaf mineral nutrient contents as well as biomass and cardenolide productions were determined. The soils in the four collection sites, basic and highly calcareous, showed significant interpopulation differences in phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg), manganese (Mn), copper (Cu), and zinc (Zn). Foliar mineral nutrients and cardenolides also varied among populations. Highest cardenolide yield was found in those Digitalis populations presenting a better development. The cardenolide content exhibited significant negative correlations with the levels …
Novedades taxonómicas y nomenclaturales para la flora valenciana, II
2010
Continuando con la actualización taxonómica y nomenclatural de la flora valenciana, se proponen diez combinaciones nuevas y un nombre nuevo para táxones y nototáxones que crecen en el Mediterráneo occidental. Además, se designa un epitipo para Sideritis × angustifolia Lag., híbrido sobre cuya identidad ha existido gran controversia, y un lectotipo para Globularia linifolia Lam. Del mismo modo, se discute la citación correcta del lugar y fecha de publicación de cuatro táxones más. Taxonomic and nomenclatural novelties concerning the Valencian flora (eastern Spain), II: As a part of the taxonomical and nomenclatural update of vascular flora of the Valencian Community, ten new combinations and…
Inhibition of the pro-inflammatory mediators' production and anti-inflammatory effect of the iridoid scrovalentinoside.
2007
We have studied scrovalentinoside, an iridoid with anti-inflammatory properties isolated from Scrophularia auriculata ssp. pseudoauriculata, as an anti-inflammatory agent in different experimental models of delayed-type hypersensitivity. We found that scrovalentinoside reduced the edema induced by oxazolone at 0.5 mg/ear and sheep red blood cells at 10 mg/kg. The observed effect occurred during the last phase or inflammatory response; during the earlier phase or induction of the delayed-type hypersensitivity reaction, no significant activity was noted. Thus, scrovalentinoside reduced both the edema and cell infiltration in vivo and reduced lymphocyte proliferation in vitro, affecting the cy…
Digitalis obscura cardenolides. Effect of macronutrient concentration and N source on growth and productivity of shoot-tip cultures
1997
Abstract Changes in nutrient medium formulation in terms of major salt concentration or N source significantly modified cardenolide production by Digitalis obscura (genotype T4) shoot-tip cultures. A positive correlation between morphogenetic responses, culture growth, and proliferative capacity on one side and metabolite biosynthesis on the other cannot be established. The final stages of microprogation, rooting, and acclimatization of D. obscura were improved by using paclobutrazol.
Seasonal cardenolide production and Dop5βr gene expression in natural populations of Digitalis obscura
2004
Productivity variations and seasonal fluctuations of cardenolides have been studied in 10 natural populations of Digitalis obscura distributed in three bioclimatic belts. Main cardenolides in D. obscura plants are those of the series A and such predominance (ca. 80-85%) over the series B metabolites is independent of the population studied or the degree of maturity of the leaves. Primary glycosides represent ca. 50-60% of total cardenolides; this percentage did not vary among populations or with the leaf age but increased in summer and decreased in winter. A correlation analysis between plant biomass and cardenolide content showed a positive relationship of these parameters, which, accordin…