6533b85efe1ef96bd12bfb40
RESEARCH PRODUCT
Screening of antiinflammatory medicinal plants used in traditional medicine against skin diseases
Rosa-maría GinerS. CerdáM. J. CuéllarSalvador MáñezJosé-luis RíosMaría-carmen RecioMaria Jose Justsubject
PharmacologyForsythia suspensaintegumentary systemTraditional medicinebiologybusiness.industryScrophularia auriculatabiology.organism_classificationlaw.inventionSantolina chamaecyparissusAstragaluschemistry.chemical_compoundPhospholipase A2chemistrylawbiology.proteinMedicineArachidonic acidPhytotherapyMedicinal plantsbusinessdescription
The antiinflammatory activity of twelve medicinal plants used against skin disorders were tested in different experimental models of topical inflammation and one in vitro inhibitory test against phospholipase A2 (PLA2) from Naja naja venom. Forsythia suspensa was the most active species on the arachidonic acid (AA) topical test. This last species together with Astragalus membranaceus and Ranunculus sceleratus were the most active on the 12-O-tetradecanoylphorbol-13-acetate (TPA) acute ear oedema test. Scrophularia auriculata was the most active on multiple topical applications of TPA and on the oxazolone-induced delayed type hypersensitivity (DTH). Santolina chamaecyparissus was the only species that inhibited PLA2in vitro. © 1998 John Wiley & Sons, Ltd.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1998-02-01 | Phytotherapy Research |