Search results for "Humor"
showing 10 items of 220 documents
Recent advances on HIV DNA vaccines development: Stepwise improvements to clinical trials.
2019
According to WHO (World Health Organization) reports, more than 770,000 people died from HIV and almost 1.7 million people becoming newly infected in the worldwide in 2018. Therefore, many attempts should be done to produce a forceful vaccine to control the AIDS. DNA-based vaccines have been investigated for HIV vaccination by researches during the recent 20 years. The DNA vaccines are novel approach for induction of both type of immune responses (cellular and humoral) in the host cells and have many advantages including high stability, fast and easy of fabrication and absence of severe side effects when compared with other vaccination methods. Recent studies have been focused on vaccine de…
The Antibody Response to the BNT162b2 mRNA COVID-19 Booster in Healthcare Workers: Association between the IgG Antibody Titers and Anthropometric and…
2022
Background: Research shows that in most people, two-dose vaccination helps to shape the humoral response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Further studies are required to learn about the vaccine’s effectiveness after boosting. Methods: We conducted a prospective study among 103 healthcare workers (HCWs) from a regional multi-specialty hospital vaccinated with three doses of the BNT162b2 vaccine. We compared their immunoglobulin G (IgG) titers 14 days after the second dose with those 21 days after the booster. We also compared their anthropometric and body composition parameters with IgG concentrations at the same time points. Results: Twenty-one days aft…
Der Komiker als Philosoph. Humor und Heilung Bei Hape Kerkeling
2019
espanolEl famoso comico, actor, moderador y escritor aleman Hape Kerkeling se dio a conocer internacionalmente como peregrino en el Camino de Santiago en su exito de ventas Ich bin dann mal weg (2006), el libro de divulgacion aleman mas vendido en la historia de RFA. Igualmente famosas se hicieron sus memorias Der Junge muss an die frische Luft – Meine Kindheit und ich (2014), que ocuparon mas de veinte semanas el primer puesto de la lista de los libros mas vendidos en Alemania y cuya adaptacion cinematografica llegara a los cines en diciembre de 2018. Ambas obras muestran dos facetas del autor, la de comico y la de filosofo, que le permiten ir en busca de su epifania o iluminacion personal…
Politiskā komunikācija - interneta joku resurss
2016
Darba tēma: Politiskā komunikācija – interneta joku resurss. Darba mērķis: izpētīt interneta humoru par politisko komunikāciju, noskaidrot, kā jaunieši uztver tajā ietvertos politiķus un, kā novērtē politisko darbību. Darba uzdevumi: literatūras studijas, politiskās komunikācijas gadījumu un interneta humora izpēte, jauniešu aptaujāšana, datu analīze. Teorētiskā pieeja: Dž. Fiske, E. Grifins, K. Sandersa, B. MakNairs, B. Pfetša, F. Esers, R. Negrine, T. Benski, E. Fišers, R. Šmite, M. Kastels. F. L. F. Lī, Dž. C. Baumgartnere. Metodoloģija: literatūras studijas, kvalitatīvā kontentanalīze, aptauja, kvantitatīva datu apstrāde. Pētījuma rezultāti: jaunieši, kuri ir redzējuši interneta politis…
An elongation factor-like protein (EF-Tu) elicits a humoral response in infiltrating ductal breast carcinomas: an immunoproteomics investigation.
2011
Abstract Objectives In the current study, we have used an immunoproteomics approach to identify proteins that commonly elicit a humoral response in patients with infiltrating ductal carcinomas of the breast. Design and methods Sera obtained at the time of diagnosis from 40 patients with invasive breast cancer and 42 healthy controls were screened for the presence of IgG antibodies to MCF-7 cell line proteins using a serological proteomics-based approach. Results An immunoreactive protein detected in sera from 21 of 40 patients was isolated and subsequently identified as elongation factor-Tu. Conclusions The immunoproteomic approach implemented here offers a powerful tool for determining nov…
Common Factors in Neurodegeneration: A Meta-Study Revealing Shared Patterns on a Multi-Omics Scale
2020
Neurodegenerative diseases such as Alzheimer&rsquo
Socially Critical Humor : Discussing Humor with Erich Fromm and Theodor W. Adorno
2017
This article brings Erich Fromm and Theodor W. Adorno back into dialogue by discussing the cultural phenomena of humor and laughter based on their theoretical writings. I argue that what is typically considered socially critical humor, like offensive jokes or harsh satire, often fails to meet the preconditions of criticism in the light of Adorno’s and Fromm’s thinking. Humor, to be socially critical, has to be life-affirmative and non-positional, and it has to challenge the limits of humor. It is also claimed that in this scope, humor cannot be instrumental.
Humoral immune responses of lung cancer patients against the Transmembrane Phosphatase with TEnsin homology (TPTE).
2015
Abstract Objective The cancer/testis (C/T) antigen Transmembrane Phosphatase with TEnsin homology (TPTE) is aberrantly expressed in many tumors including lung cancer. In the present study, we analyzed TPTE-auto-antibodies in lung cancer patients. Methods Using a crude-lysate ELISA, we analyzed a large cohort of 307 sera from lung cancer patients and 47 healthy donors for TPTE-specific autoantibodies. Sero-reactivity was correlated with clinical parameters and patients’ survival. Results TPTE-specific antibodies were detected in 41 of 307 (13.4%) sera from lung cancer patients. Based on an optimal cut-off value calculated by ROC curve analysis sensitivity for diagnosing lung cancer was 52% a…
Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa.
2013
Retinitis Pigmentosa is a common form of hereditary retinal degeneration constituting the largest Mendelian genetic cause of blindness in the developed world. It has been widely suggested that oxidative stress possibly contributes to its pathogenesis. We measured the levels of total antioxidant capacity, free nitrotyrosine, thiobarbituric acid reactive substances (TBARS) formation, extracellular superoxide dismutase (SOD3) activity, protein, metabolites of the nitric oxide/cyclic GMP pathway, heme oxygenase-I and inducible nitric oxide synthase expression in aqueous humor or/and peripheral blood from fifty-six patients with retinitis pigmentosa and sixty subjects without systemic or ocular …
Efficacy of a bivalent vaccine against eel diseases caused by Vibrio vulnificus after its administration by four different routes
2003
Vulnivaccine, a vaccine against vibriosis caused by Vibrio vulnificus serovar E (formerly biotype 2), confers acceptable levels of protection to eels after its administration by prolonged immersion in three doses. Recently, a new pathogenic serovar, named serovar A, has been isolated from vaccinated eels in a Spanish freshwater eel farm. The main objective of this work was to design a bivalent vaccine, and to study its effectiveness against the two pathogenic serovars. With this aim, eels weighing around 20 g were immunised with the bivalent vaccine by oral and anal intubation, intraperitoneal injection (i.p.) and prolonged immersion. The overall results indicated that: (i) the new vaccine …