Search results for "Hydrazide"

showing 10 items of 87 documents

Polysaccharide-Based pH-Responsive Nanocapsules Prepared with Bio-Orthogonal Chemistry and Their Use as Responsive Delivery Systems.

2020

Bio-orthogonal reactions have become an essential tool to prepare biomaterials; for example, in the synthesis of nanocarriers, bio-orthogonal chemistry allows circumventing common obstacles related to the encapsulation of delicate payloads or the occurrence of uncontrolled side reactions, which significantly limit the range of potential payloads to encapsulate. Here, we report a new approach to prepare pH-responsive nanocarriers using dynamic bio-orthogonal chemistry. The reaction between a poly(hydrazide) crosslinker and functionalized polysaccharides was used to form a pH-responsive hydrazone network. The network formation occurred at the interface of aqueous nanodroplets in miniemulsion …

Polymers and PlasticsBioengineeringNanotechnologyBiocompatible Materials02 engineering and technology010402 general chemistryHydrazidePolysaccharide01 natural sciencesNanocapsulesArticleBiomaterialschemistry.chemical_compoundNanocapsulesPolysaccharidesMaterials Chemistrychemistry.chemical_classificationAqueous solutionChemistrytechnology industry and agricultureHydrogen-Ion Concentration021001 nanoscience & nanotechnology0104 chemical sciencesMiniemulsionNanocarriers0210 nano-technologyBiomacromolecules
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Indirect oxidation of amino acid phenylhydrazides by mushroom tyrosinase.

2006

We have investigated oxidation of amino acid phenylhydrazides by mushroom tyrosinase in the presence of 4-tert-butylcatechol and N-acetyl-l-tyrosine. Spectrophotometric measurements showed gradual disappearance of 4-tert-butyl-o-benzoquinone, generated by oxidation of 4-tert-butylcatechol with sodium periodate, after addition of amino acid phenylhydrazides. However, the presence of the phenylhydrazides did not influence the concentration of 4-tert-butyl-o-benzoquinone formed during enzymatic oxidation. Oxygen consumption measurements demonstrated that in a mixture both compounds were oxidized but the reaction rate was proportional to the concentration of the catechol. In the oxidation of N-…

Reducing agentTyrosinaseBiophysicsagaritineHydrazideBiochemistrychemistry.chemical_compoundOrganic chemistryAmino AcidsMolecular Biologyhydrazidechemistry.chemical_classificationCatecholMolecular StructureSodium periodateMonophenol MonooxygenaseSpectrum AnalysishydrazineAmino acidPhenylhydrazinesOxygenAgaritineEnzymetyrosinaseo-quinonechemistryredox exchangeAgaricalesOxidation-ReductionBiochimica et biophysica acta
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Coordination versatility of 1,5-bis(salicylidene)carbohydrazide in Ni(II) complexes

2014

Abstract Versatile coordination behavior of a polydentate Schiff base ligand 1,5-bis(salicylidene)carbohydrazide (H3bsc) has been explored in Ni(II) complexes. [Ni(H3bsc)2](ClO4)2 (1)·H2O·3CH3CN is a bis chelate mononuclear complex of H3bsc in keto form, and [Ni4(H0.5bsc)2(O2CCMe3)3(CH3OH)4](2)·2H2O·2CH3OH is a tetranuclear complex of H3bsc with an unusual coordination. In 2, one phenolate group of the ligand coordinates in a monodentate way and the other coordinates in a μ2-bridging mode to the Ni(II) center. This unusual coordination mode of the ligand stabilizes the Ni(II) complex in a tetranuclear form where the carbonyl oxygen of the ligand exists in between keto and enol form of bond …

Schiff baseDenticityLigandStereochemistryCarbohydrazideEnolBond orderInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryMaterials ChemistryAntiferromagnetismChelationPhysical and Theoretical ChemistryInorganic Chemistry Communications
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Crystal and Molecular Structure and Stability of Isoniazid Cocrystals with Selected Carboxylic Acids

2013

Reaction of isoniazid with benzoic acid, sebacic acid, suberic acid, and cinnamic acid results in formation of cocrystals. Two polymorphs of isoniazid–suberic acid and two polymorphs of isoniazid–cinnamic acid cocrystals were isolated. Crystal structure analysis shows the presence of a pyridine–carboxylic acid synthon in the studied cocrystals. The hydrazide group of isoniazid participates in N–H···O and N–H···N hydrogen bond formation, producing different supramolecular synthons. The stability study of isoniazid cocrystals has been performed over a 22 week period. A comparison of melting points of isoniazid–dicarboxylic acid 2:1 cocrystals shows the decrease of melting point with an increa…

Sebacic acidHydrogen bondSynthonGeneral Chemistrybacterial infections and mycosesCondensed Matter PhysicsHydrazideCinnamic acidchemistry.chemical_compoundchemistryPolymer chemistryOrganic chemistryGeneral Materials ScienceSolubilitySuberic acidBenzoic acidCrystal Growth & Design
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NEW BIODEGRADABLE HYDROGELS BASED ON INULIN AND alpha,beta-POLYASPARTYLHYDRAZIDE DESIGNED FOR COLONIC DRUG DELIVERY:IN VITRO RELEASE OF THE PEPTIDES …

2009

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoHYDROGELS polyaspartylhydrazide inulin
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CCDC 1534659: Experimental Crystal Structure Determination

2017

Related Article: Karolina Zdyb, Maxym O. Plutenko, Rostislav D. Lampeka, Matti Haukka, Malgorzata Ostrowska, Igor O. Fritsky, Elzbieta Gumienna-Kontecka|2017|Polyhedron|137|60|doi:10.1016/j.poly.2017.07.009

Space GroupCrystallography(2-(35-dimethyl-1H-pyrazol-1-yl)-2-(hydroxyimino)-N'-[1-(pyridin-2-yl)ethylidene]acetohydrazide)-(2-(35-dimethyl-1H-pyrazol-1-yl)-2-(hydroxyimino)-N-[1-(pyridin-2-yl)ethylidene]ethanehydrazonato)-nickel(ii) perchlorate methanol solvate monohydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1534664: Experimental Crystal Structure Determination

2017

Related Article: Karolina Zdyb, Maxym O. Plutenko, Rostislav D. Lampeka, Matti Haukka, Malgorzata Ostrowska, Igor O. Fritsky, Elzbieta Gumienna-Kontecka|2017|Polyhedron|137|60|doi:10.1016/j.poly.2017.07.009

Space GroupCrystallography(2-(35-dimethyl-1H-pyrazol-1-yl)-2-(hydroxyimino)-N'-[1-(pyridin-2-yl)ethylidene]acetohydrazide)-(2-(35-dimethyl-1H-pyrazol-1-yl)-2-(hydroxyimino)-N-[1-(pyridin-2-yl)ethylidene]ethanehydrazonato)-nickel(ii) perchlorate methanol solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1426094: Experimental Crystal Structure Determination

2016

Related Article: Philipp Veit, Ephraim Prantl, Christoph Förster, Katja Heinze|2016|Organometallics|35|249|doi:10.1021/acs.organomet.5b00963

Space GroupCrystallography(mu-N'-(cyclopenta-13-dien-1-yl(cyclopenta-24-dien-1-ylidene)methyl)-4-methylbenzenesulfonohydrazide)-bis(eta5-cyclopentadienyl)-di-rutheniumCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 799323: Experimental Crystal Structure Determination

2012

Related Article: L.Brelot, Xiao-yu Cao, J.Harrowfield, J.-M.Lehn, K.Rissanen, L.Russo|2011|CrystEngComm|13|2346|doi:10.1039/c0ce00814a

Space GroupCrystallography2581118212427-Octaoxatricyclo[26.3.1.0^1217^]dotriaconta-1(32)1214162830-hexaene-30-carbohydrazideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1587259: Experimental Crystal Structure Determination

2019

Related Article: P. Sivajeyanthi, B. Edison, K. Balasubramani, G. Premkumar, T. Swu|2019|Acta Crystallogr.,Sect.E:Cryst.Commun.|75|804|doi:10.1107/S2056989019006492

Space GroupCrystallographyCrystal System(E)-N'-((3-hydroxy-4-methoxyphenyl)methylidene)pyridine-3-carbohydrazide monohydrateCrystal StructureCell ParametersExperimental 3D Coordinates
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