Search results for "Hydride"
showing 10 items of 322 documents
A new biodegradable and biocompatible hydrogel with polyaminoacid structure
2007
The preparation and physicochemical and biological characterization of a novel polyaminoacid hydrogel have been reported. The ,-poly(N-2- hydroxyethyl)-dl-aspartamide (PHEA) has been used as a starting polymer for a derivatization reaction with methacrylic anhydride (MA) to give rise to the methacrylate derivative named PHM. Photocrosslinking of PHM has been performed in aqueous solution at 313 nm and in the absence of toxic initiators. PHM-based hydrogel has been characterized by scanning electron microscopy, X-ray diffractometry, swelling measurements in aqueous media; the degradation of PHM-based hydrogel has been evaluated as a function of time in the absence or in the presence of ester…
Photo-Cross-Linked Hydrogels with Polysaccharide−Poly(amino acid) Structure: New Biomaterials for Pharmaceutical Applications
2006
The aim of this work has been the preparation and characterization of novel hydrogels with polysaccharide-poly(amino acid) structure having suitable physicochemical properties for pharmaceutical applications. In the first step, hyaluronic acid (HA) and alpha,beta-poly(N-2-hydroxyethyl)-DL-aspartamide (PHEA) have been derivatized with methacrylic anhydride (AMA), thus obtaining HA-AMA and PHM derivatives, respectively. In the second step, aqueous solutions of both these derivatives have been irradiated at 313 nm to obtain chemical hydrogels. The hydrogel obtained by irradiating for 15 min an aqueous solution containing 4% w/v of HA-AMA and 4% w/v of PHM resulted in the highest yield. Its swe…
On Transition Structures for Hydride Transfer Step in Enzyme Catalysis. A Comparative Study on Models of Glutathione Reductase Derived from Semiempir…
1996
As a model of the chemical reactions that take place in the active site of gluthatione reductase, the nature of the molecular mechanism for the hydride transfer step has been characterized by means of accurate quantum chemical characterizations of transition structures. The calculations have been carried out with analytical gradients at AM1 and PM3 semiempirical procedures, ab initio at HF level with 3-21G, 4-31G, 6-31G, and 6-31G basis sets and BP86 and BLYP as density functional methods. The results of this study suggest that the endo relative orientation on the substrate imposed by the active site is optimal in polarizing the C4-Ht bond and situating the system in the neighborhood of the…
Chromatographic and mass spectrometric characteristics of 20-dihydroaldosterone.
1992
The 20 alpha-reduced derivative of aldosterone, 20 alpha-dihydroaldosterone, was needed as reference compound in order to continue the studies on 18-hydroxylation in the Y-1 adrenal cell line. It was obtained by reduction of aldosterone with sodium borohydride. Analysis of the products of the reaction as methoxime trimethylsilyl (MO-TMS) derivatives by gas chromatography (GC) and GC-mass spectrometry (GC-MS) showed three possible forms of the compound. Their identification was confirmed by comparison with the products obtained by stereospecific reduction of aldosterone using 3 alpha,20 beta-hydroxysteroid dehydrogenase. Chromatographic behavior and mass spectra are given for the three forms…
Synthesis and Structural Characterization of (1,4-Dihydropyrid-1-yl)aluminum Complexes
1999
The reaction between LiAlH(4) and pyridine, 4-methylpyridine, or 3,5-dimethylpyridine results in hydride transfer to the pyridine ring to give tetrakis(pyridine)lithium tetrakis(1,4-dihydropyrid-1-yl)aluminate(III), 1, tetrakis(4-methylpyridine)lithium tetrakis(1,4-dihydro-4-methylpyrid-1-yl)aluminate(III), 2, or tetrakis(3,5-dimethylpyridine)lithium tetrakis(3,5-dimethyl-1,4-dihydropyrid-1-yl)aluminate(III), 3, respectively. We claim that 1, instead of lithium tetrakis(1,4-dihydropyrid-1-yl)aluminate(III), is the compound which is known as Lansbury's reagent. Treatment of trimethylamine-alane, AlH(3).NMe(3), with pyridine yields tris(1,4-dihydropyrid-1-yl)(pyridine)aluminum, 4. It could be…
An Unprecedented Iridium(III) Catalyst for Stereoselective Dimerisation of Terminal Alkynes
2008
A novel iridium(III) hydride complex, IrHCl(TIMP 3 ) {HTIMP 3 = tris[1-(diphenylphosphino)-3-methyl-lH-indol-2-yl]methane) was prepared and fully characterized in both the solid state and in solution. Chloride abstraction by silver cations provides a more reactive compound, [IrH-(TIMP 3 )][BF 4 ], which can react with pyridine (py) and phenylacetylene to yield the complexes [IrH-(TIMP 3 )(py)][BF 4 ] and [Ir(PhCH=C-CH=CHPh)-(TIMP 3 )][BF 4 ], respectively. Interestingly, IrH-(TIMP 3 )(py)][BF 4 ] efficiently catalyses the stereoselective dimerisation of model terminal alkynes to the 1,4-disubstituted (E)-but-1-en-3-yne only.
Dynamic mechanical properties of semi-interpenetrating networks based on poly(styrene-co-maleic anhydride)
1991
Semi-interpenetrating networks based on linear anionic polystyrene (PS) and poly(styrene-co-maleic anhydride) P(ScoMA) of low MA content are prepared by crosslinking the P(ScoMA) with 4,4′-diphenylmethanediamine (DPMDA). It is demonstrated by dynamic mechanical analysis and by DSC that immiscible semi-IPN's are obtained for MA contents greater 5 wt.-%. In miscible semi-IPN's the relaxation of free PS chains is observed as a second maximum in the loss tangent at higher temperatures. The position of this maximum is shifted to higher temperatures for a polystyrene of molecular weight 500000 compared to a polystyrene of molecular weight 150000. The experimental temperature shift is in good agre…
Determination of extremely low (236)U/(238)U isotope ratios in environmental samples by sector-field inductively coupled plasma mass spectrometry usi…
2005
A method by inductively coupled plasma mass spectrometry (ICP-MS) was developed which allows the measurement of (236)U at concentration ranges down to 3 x 10(-14)g g(-1) and extremely low (236)U/(238)U isotope ratios in soil samples of 10(-7). By using the high-efficiency solution introduction system APEX in connection with a sector-field ICP-MS a sensitivity of more than 5,000 counts fg(-1) uranium was achieved. The use of an aerosol desolvating unit reduced the formation rate of uranium hydride ions UH(+)/U(+) down to a level of 10(-6). An abundance sensitivity of 3 x 10(-7) was observed for (236)U/(238)U isotope ratio measurements at mass resolution 4000. The detection limit for (236)U a…
Gas chromatography-mass spectrometry characterization of the varnish and glue of an ancient 18th century double bass.
2007
A GC–MS investigation is conducted on the double bass “Panormus”, property of Conservatorio di Musica “Vincenzo Bellini” in Palermo. The most important components of the varnish (fatty acids) and of the glue (proteinaceous amino acids), with which the musical instrument was treated in the past, are determined. The analyses are carried out by prior derivatization of fatty acids by acidic methanol and of amino acids by acidic methanol and trifluoroacetic anhydride (TFAA). Analytes identification is achieved by direct comparison with several reference materials and the use of a digitized library.
Self-sufficient PV-H2 Alternative Energy Objects
2016
Energy storage becomes more important as mankind switch to renewable energy, away from fossil resources. Traditional way – batteries - offer a limited number of cycles, require regular maintenance; nevertheless gravitational storage, flywheels, compressed air are mainly large scale and expensive methods. The hydrogen as energy carrier and hydrogen fuel cells are possible option to store different amounts of energy for relatively long times with low losses. Different solutions for self-sufficient sun/wind energy objects are analysed - the solar radiation collecting systems, wind power generators, and high pressure electrolysis technologies for hydrogen production and the metal-hydride energy…