Search results for "IAT"

showing 10 items of 33873 documents

Advanced Management Protocol of Transanal Irrigation in Order to Improve the Outcome of Pediatric Patients with Fecal Incontinence

2021

Background: Transanal irrigation (TAI) is employed for children with fecal incontinence, but it can present several problems which require a study of their outcomes among different pathologies and without a tailored work up. The aim of our study was to evaluate the effectiveness of an advanced protocol in order to tailor TAI, prevent complications, and evaluate outcomes. Methods: We included 70 patients (14 anorectal malformation, 12 Hirschsprung’s disease, 24 neurological impairment, 20 functional incontinence) submitted to a comprehensive protocol with Peristeen®: fecal score, volumetric enema, rectal ultrasound, anorectal 3D manometry, and diary for testing and parameter adjustment. Resu…

transanal irrigationfecal incontinencechildrentransanal irrigation; fecal incontinence; anorectal high-resolution manometry; childrenPediatrics Perinatology and Child HealthSettore MED/20 - Chirurgia Pediatrica E Infantileanorectal high-resolution manometryPediatricsRJ1-570ArticleChildren; Volume 8; Issue 12; Pages: 1174
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Improving the Effect of Transcranial Alternating Current Stimulation (tACS): A Systematic Review

2021

With the development of electrical stimulation technology, traditional transcranial alternating current stimulation (tACS) technology has been found to have the drawback of not targeting a specific area accurately. Studies have shown that optimizing the number and position of electrodes during electrical stimulation has a very good effect on enhancing brain stimulation accuracy. At present, an increasing number of laboratories have begun to optimize tACS. However, there has been no study summarizing the optimization methods of tACS. Determining whether different optimization methods are effective and the optimization approach could provide information that could guide future tACS research. …

transcranial alternating current stimulationComputer scienceNeurosciences. Biological psychiatry. Neuropsychiatrychemical and pharmacologic phenomenaHuman NeuroscienceReviewhigh definition electrical stimulationintersectional short pulse methodBehavioral NeurosciencePsychiatry and Mental healthstomatognathic diseasesNeuropsychology and Physiological PsychologyNeurologystomatognathic systemBrain stimulationphase-shifted tACSElectronic engineeringOptimization methodstemporally interfering methodBiological Psychiatryamplitude modulated tACSRC321-571Transcranial alternating current stimulationFrontiers in Human Neuroscience
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Extracellular Vesicle microRNAs Contribute to the Osteogenic Inhibition of Mesenchymal Stem Cells in Multiple Myeloma

2020

Osteolytic bone disease is the major complication associated with the progression of multiple myeloma (MM). Recently, extracellular vesicles (EVs) have emerged as mediators of MM-associated bone disease by inhibiting the osteogenic differentiation of human mesenchymal stem cells (hMSCs). Here, we investigated a correlation between the EV-mediated osteogenic inhibition and MM vesicle content, focusing on miRNAs. By the use of a MicroRNA Card, we identified a pool of miRNAs, highly expressed in EVs, from MM cell line (MM1.S EVs), expression of which was confirmed in EVs from bone marrow (BM) plasma of patients affected by smoldering myeloma (SMM) and MM. Notably,we found that miR-129-5p, whic…

transcription factor sp1.Cancer ResearchBone diseaseosteogenic differentiationexosomeslcsh:RC254-282transcription factor sp1ArticleSettore MED/15 - Malattie Del SangueSettore BIO/13 - Biologia Applicatamedicinemultiple myeloma (MM)ChemistrySettore BIO/16 - Anatomia UmanaMesenchymal stem cellALPLOsteoblastMicroRNAExtracellular vesiclemedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensSettore CHIM/08 - Chimica FarmaceuticaCell biologymicroRNAsExosomemedicine.anatomical_structureOncologyCell cultureAlkaline phosphatasebone diseaseBone marrowextracellular vesicles (EVs)Cancers
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The Effects of Transcutaneous Spinal Direct Current Stimulation on Neuropathic Pain in Multiple Sclerosis: Clinical and Neurophysiological Assessment

2019

Background: Central neuropathic pain represents one of the most common symptoms in multiple sclerosis (MS) and it seriously affects quality of life. Spinal mechanisms may contribute to the pathogenesis of neuropathic pain in MS. Converging evidence from animal models and neurophysiological and clinical studies in humans suggests a potential effect of transcranial direct current stimulation (tc-DCS) on neuropathic pain. Spinal application of DCS, i.e., transcutaneous spinal DCS (ts-DCS), may modulate nociception through inhibition of spinal reflexes. Therefore, ts-DCS could represents an effective, safe and well-tolerated treatment for neuropathic pain in MS, a largely unexplored topic. This…

transcutaneous spinal direct current stimulation (ts-DCS)nociceptive withdrawal reflexmedicine.medical_treatmentnon-invasiveWithdrawal reflexmultiple sclerosis050105 experimental psychologylcsh:RC321-57103 medical and health sciencesBehavioral Neuroscience0302 clinical medicinemedicine0501 psychology and cognitive sciencesSpasticitylcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological PsychiatryOriginal Researchneuropathic painTranscranial direct-current stimulationbusiness.industryMultiple sclerosis05 social sciencesmedicine.diseaseNeuromodulation (medicine)Psychiatry and Mental healthNeuropsychology and Physiological PsychologyNociceptionNeurologyAnesthesianeuromodulationNeuropathic painmultiple sclerosis; neuromodulation; neuropathic pain; nociceptive withdrawal reflex; non-invasive; transcutaneous spinal direct current stimulation (ts-DCS)Reflexmedicine.symptombusiness030217 neurology & neurosurgeryNeuroscienceFrontiers in Human Neuroscience
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Transexualidad y Adolescencia: Una revisión sistemática

2018

El estudio de la transexualidad ha evolucionado en los últimos años alcanzando mayor visibilidad actualmente gracias a las iniciativas de los colectivos trans y al incremento de niños, niñas y adolescentes que acuden a atención primaria por problemas de identidad de género. Este creciente interés ha estimulado la investigación cuya abundancia precisa un análisis y selección de los trabajos más relevantes. Con este objetivo hemos realizado una revisión bibliográfica con el fin de abordar el estado actual de la transexualidad temprana, centrándonos en los estudios relativos a su etiología, prevalencia, diagnóstico y tratamientos actuales. Para ello se consultaron diversas bases de datos (Web …

transexuality03 medical and health sciences0302 clinical medicineadolescencia030225 pediatrics05 social sciencestransexualidad0501 psychology and cognitive sciencesadolescenceproceso transexualizadortransexualizing process050104 developmental & child psychology
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Educación XX1 : revista de la Facultad de Educación

2016

Resumen basado en el de la publicación Título, resumen y palabras clave también en inglés Se indaga sobre las evidencias en torno a cómo se reciben en los centros escolares los equipamientos tecnológicos (el KidSmart en este caso). Se asume, a modo de hipótesis, que el grado de asimilación por parte de los miembros de la organización de la tecnología transferida, es un factor determinante del grado de uso. El trabajo de campo se realiza en los centros de educación infantil que participan en el proyecto «El Rincón del Ratón». Mediante grabaciones de clase, encuestas y observaciones se ha tratado de obtener evidencias sobre el problema de investigación. Los primeros resultados ponen de manifi…

transferencia de tecnologíacambio tecnológicoAppropriationEarly resultsadministración educativaTechnology transfereducación preescolarSociologytecnología de la educaciónlcsh:LHumanitieslcsh:EducationEducationEducación XX1
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Le livre audio en bibliothèque de lecture publique : dispositifs de médiation et formes de prescription d’un support « mineur »

2019

International audience; À partir d’une enquête sur les discours et pratiques liés au livre audio du côté d’usagers et de bibliothécaires menée à l’occasion d’un projet de recherche-action dans trois bibliothèques de lecture publique françaises, nous essayons dans cet article de faire avancer la réflexion autour de la notion de prescription, historiquement ancrée dans la figure du bibliothécaire, et de travailler en particulier les écarts entre la prescription d’un format qui reste un impensé de la profession et la médiation d’une expérience d’écoute de la littérature. Cet écart a des conséquences sur la manière dont les « audio lecteurs » parviennent à dire et à partager leurs pratiques. No…

transformation organisationnelleprescription[SHS.SOCIO]Humanities and Social Sciences/Sociology[SHS.SOCIO] Humanities and Social Sciences/Sociology[SHS.INFO]Humanities and Social Sciences/Library and information sciencesbibliothèque de lecture publique[SHS.INFO] Humanities and Social Sciences/Library and information sciences[SHS]Humanities and Social Scienceslivres audioservices en ligneidentité professionnelleressources et prêt numérique en bibliothèque[SHS] Humanities and Social Sciencesmédiation
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Structuration du territoire bourguignon : de l'île à l'isthme

2006

Three principles govern the structuration of the burgundian territory. Its internal organization, with the peripheral location of its most active areas, is similar to the organization of an island. Its situation within national and European space makes it an area of multiple transitions, an unsettled organization, submissive to strong centrifugal forces which can threaten its unity. Lastly, it has always been crossed by numerous links, it is an intermediate space between nodes, strongly marked with networks and exogenous traffic which criss-cross its territory.

transitsrégion[SHS.GEO] Humanities and Social Sciences/Geographycentre and peripheryintermediate space[SHS.GEO]Humanities and Social Sciences/Geographytrafficsstructuration territorialeespace intermédiairenodalitéréseau[ SHS.GEO ] Humanities and Social Sciences/Geographyterritorial structurationnetworkBourgognecentre et périphérienodality
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The Extractive Industries Transparency Initiative (EITI) in Cameroon : realities and prospects

2010

For a long time, Cameroon was a success story in the context of Africa’s development. Unfortunately, the economic crises of the eighties and early nineties led to the failure of the development strategies that had been pursued until then, resulting in a severe deterioration of the country’s economy and the living standards of the Cameroonian people (Mentan, 2003). However, this country possesses significant oil wealth which if properly managed can generate abundant revenue to boost economic growth and fund anti-poverty measures. In 2005, Cameroon adhered to the Extractive Industries Transparency Initiative (EITI). A proper implementation of this initiative will improve transparency in the c…

transparencyEITIläpinäkyvyysExtractive Industries Transparency Initiativethe Gulf of GuineakehitysmaatdemokratiaCameroonkehitysoildevelopmentöljyKamerun
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Energy efficient model for biogas production in farm scale

2011

Energy efficient solutions for six farm biogas production was found by calculating mass and energy balance in different scenarios. Raw materials in biogas production were cow manure and grass silage that were produced in these farms. There were calculated mass and energy balances on average for one year biogas prouduction that consisted of grass silage production, raw material transportation and biogas production in the biogas plant. In addition, direct greenhouse gases from biogas production were estimated. The direct mass and energy flows were calculated. It turned out that one input energy unit can produce 5.0 to 5.5 energy units as heat and electricity. Biogas reactor consumed heat from…

transportationenergiamaatilatbiogas reactorbiokaasugreenhouse gas emissionsLCAkuljetuskulutusBiogas productiongrass silage productionmass and energy balancekasvihuonekaasutenergy consumptionnurmirehutthe cluster of farmstuotantoenergiatase
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