Search results for "ICAD"
showing 10 items of 1297 documents
Current rectification by nanoparticle blocking in single cylindrical nanopores.
2014
Blocking of a charged pore by an oppositely charged nanoparticle can support rectifying properties in a cylindrical nanopore, as opposed to the usual case of a fixed asymmetry in the pore geometry and charge distribution. We present here experimental data and model calculations to confirm this fundamental effect. The nanostructure imaging and the effects of nanoparticle concentration, pore radius, and salt concentration on the electrical conductance–voltage (G–V) curves are discussed. Logic responses based on chemical and electrical inputs/outputs could also be implemented with a single pore acting as an effective nanofluidic diode. To better show the generality of the results, different ch…
Engineered axon tracts within tubular biohybrid scaffolds
2021
[EN] Injuries to the nervous system that involve the disruption of axonal pathways are devastating to the individual and require specific tissue engineering strategies. Here we analyse a cells-biomaterials strategy to overcome the obstacles limiting axon regeneration in vivo, based on the combination of a hyaluronic acid (HA) single-channel tubular conduit filled with poly-L-lactide acid (PLA) fibres in its lumen, with pre-cultured Schwann cells (SCs) as cells supportive of axon extension. The HA conduit and PLA fibres sustain the proliferation of SC, which enhance axon growth acting as a feeder layer and growth factor pumps. The parallel unidirectional ensemble formed by PLA fibres and SC …
A description based on languages of the final non-deterministic automaton
2014
The study of the behaviour of non-deterministic automata has traditionally focused on the languages which can be associated to the different states. Under this interpretation, the different branches that can be taken at every step are ignored. However, we can also take into account the different decisions which can be made at every state, that is, the branches that can be taken, and these decisions might change the possible future behaviour. In this case, the behaviour of the automata can be described with the help of the concept of bisimilarity. This is the kind of description that is usually obtained when the automata are regarded as labelled transition systems or coalgebras. Contrarily t…
Managing expert knowledge in water network expansion project implementation
2021
[EN] The implementation of expansion projects of water networks supplying growing cities is deemed to be a complex decision-making problem involving both technical aspects and expert knowledge. Management and control processes must rely on experts in the field whose know-how must be coupled with techniques able to deal with the natural subjectivity that affects input evaluations. Given the presence of many decision-making elements, the choice of proper hydraulic technical parameters may be linked to the main aspects of analysis requiring formal expert evaluation. In this contribution, the simulation of hydraulic indicators is integrated with a multi-criteria approach able to eventually dete…
The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Tri…
2021
This article belongs to the Collection The Biomarkers for the Diagnosis and Prognosis in Cancer.
Label-free histamine detection with nanofluidic diodes through metal ion displacement mechanism
2017
[EN] We design and characterize a nanofluidic device for the label-free specific detection of histamine neurotransmitter based on a metal ion displacement mechanism. The sensor consists of an asymmetric polymer nanopore fabricated via ion track-etching technique. The nanopore sensor surface having metal-nitrilotriacetic (NTA-Ni2+) chelates is obtained by covalent coupling of native carboxylic acid groups with N-alpha,N-alpha-bis(carboxymethyl)-L-lysine (BCML), followed by exposure to Ni2+ ion solution. The BCML immobilization and subsequent Ni2+ ion complexation with NTA moieties change the surface charge concentration, which has a significant impact on the current-voltage (I-V) curve after…
Enantioselective Addition of Nitromethane to 2-Acylpyridine N-Oxides. Expanding the Generation of Quaternary Stereocenters with the Henry Reaction
2014
[EN] The direct asymmetric Henry reaction with prochiral ketones, leading to tertiary nitroaldols, is an elusive reaction so far limited to a reduced number of reactive substrates such as trifluoromethyl ketones or alpha-keto carbonyl compounds. Expanding the scope of this important reaction, the direct asymmetric addition of nitromethane to 2-acylpyridine N-oxides catalyzed by a BOX-Cu(II) complex to give the corresponding pyridine-derived tertiary nitroaldols having a quaternary stereogenic center with variable yields and good enantioselectivity, is described.
Permutable subnormal subgroups of finite groups
2009
The aim of this paper is to prove certain characterization theorems for groups in which permutability is a transitive relation, the so called PT -groups. In particular, it is shown that the finite solvable PT -groups, the finite solvable groups in which every subnormal subgroup of defect two is permutable, the finite solvable groups in which every normal subgroup is permutable sensitive, and the finite solvable groups in which conjugatepermutability and permutability coincide are all one and the same class. This follows from our main result which says that the finite modular p-groups, p a prime, are those p-groups in which every subnormal subgroup of defect two is permutable or, equivalentl…
On the product of a π-group and a π-decomposable group
2007
[EN] The main result in the paper states the following: Let π be a set of odd primes. Let the finite group G=AB be the product of a π -decomposable subgroup A=Oπ(A)×Oπ′(A) and a π -subgroup B . Then Oπ(A)⩽Oπ(G); equivalently the group G possesses Hall π -subgroups. In this case Oπ(A)B is a Hall π-subgroup of G. This result extends previous results of Berkovich (1966), Rowley (1977), Arad and Chillag (1981) and Kazarin (1980) where stronger hypotheses on the factors A and B of the group G were being considered. The results under consideration in the paper provide in particular criteria for the existence of non-trivial soluble normal subgroups for a factorized group G.
On finite groups generated by strongly cosubnormal subgroups
2003
[EN] Two subgroups A and B of a group G are cosubnormal if A and B are subnormal in their join and are strongly cosubnormal if every subgroup of A is cosubnormal with every subgroup of B. We find necessary and sufficient conditions for A and B to be strongly cosubnormal in and, if Z is the hypercentre of G=, we show that A and B are strongly cosubnormal if and only if G/Z is the direct product of AZ/Z and BZ/Z. We also show that projectors and residuals for certain formations can easily be constructed in such a group. Two subgroups A and B of a group G are N-connected if every cyclic subgroup of A is cosubnormal with every cyclic subgroup of B (N denotes the class of nilpotent groups). Thou…