Search results for "ICAD"
showing 10 items of 1297 documents
Understanding the meaning
2009
This article provides an overview of the nature of meaning, emphasizing the associative character of lexical meanings. The essay also comments on the meaning-related difficulties the translator must often overcome in order to reach a coherent interpretation due to the dubious quality of many original texts. The author illustrates this point through texts from the European Union. He also discusses some exceptional situations, especially regarding religious and traditional texts such as the Lord’s Prayer, whose formal power, including the magical ring of words, seems to outshine the alleged universal need for coherence and signification. Thus, any attempt to promote an alternative translation…
A note on finite PST-groups
2007
[EN] A finite group G is said to be a PST-group if, for subgroups H and K of G with H Sylow-permutable in K and K Sylow-permutable in G, it is always the case that H is Sylow-permutable in G. A group G is a T*-group if, for subgroups H and K of G with H normal in K and K normal in G, it is always the case that H is Sylow-permutable in G. In this paper, we show that finite PST-groups and finite T*-groups are one and the same. A new characterisation of soluble PST-groups is also presented.
Intervenció Logopèdica en els trastorns del Llenguatge d'Etiologia Central
2021
L’assignatura Intervenció Logopèdica en els Trastorns del Llenguatge d’Etiologia Central és una assignatura adscrita al Departament de Psicologia Bàsica, pertanyent a la Facultat de Psicologia i Logopèdia de la Universitat de València. És una assignatura de caràcter obligatori i semestral que consta de 9 crèdits (ECTS), equivalents a 225 hores de treball de l’alumne. S’imparteix en el primer quadrimestre del tercer curs del Grau en Logopèdia. L’assignatura es distribueix en 3 blocs ben diferenciats. El primer, bloc 1, és un bloc introductori a la matèria i el seu objectiu és que els estudiants coneguen els fonaments neurològics i els mecanismes de la rehabilitació en els trastorns del lleng…
Enantioselective Synthesis of 5-Trifluoromethyl-2-oxazolines under Dual Silver/Organocatalysis.
2019
[EN] The first enantioselective formal [3 + 2] cycloaddition between ¿-isocyanoesters and trifluoromethylketones to give 5-trifluoromethyl-2-oxazolines bearing two contiguous stereogenic centers, one of them being a quaternary stereocenter substituted with a CF3 group, has been developed. The reaction is based upon a multicatalytic approach that combines a bifunctional Brønsted base-squaramide organocatalyst and Ag+ as Lewis acid. The reaction could be achieved with a range of aryl and heteroaryl trifluoromethyl ketones, and the resulting oxazolines were obtained with good to excellent diastereo- and enantioselectivity.
Copper-catalysed enantioselective Michael addition of malonic esters to β-trifluoromethyl-α,β-unsaturated imines
2017
[EN] Copper triflate-BOX complexes catalyse the enantioselective conjugate addition of methyl malonate to beta-trifluoromethyl-alpha,beta-unsaturated imines to give the corresponding enamines bearing a trifluoromethylated stereogenic centre with good yields, and diastereo- and enantioselectivities. The usefulness of the method has been shown with the synthesis of optically active beta-trifluoromethyl delta-amino esters and optically active trifluoromethyl piperidones.
Catalytic Enantioselective Conjugate Alkynylation of α,β-Unsaturated 1,1,1-Trifluoromethyl Ketones with Terminal Alkynes.
2016
The first catalytic enantioselective conjugate alkynylation of α,β-unsaturated 1,1,1-trifluoromethyl ketones has been carried out. Terminal alkynes and 1,3-diynes were treated with trifluoromethyl ketones in the presence of a low catalytic load of a CuI-MeOBIPHEP complex (2.5 mol %) and triethylamine (10 mol %) to give the corresponding trifluoromethyl ketones bearing a propargylic stereogenic center at the β position with good yields and excellent enantiomeric excesses in most of the cases. No 1,2-addition products were formed under the reaction conditions. The procedure showed broad substrate scope for alkyne, diyne, and enone. A rationale for the observed stereochemistry has been provide…
Highly enantioselective copper(I)-catalyzed conjugate addition of 1,3-diynes to a,b-unsaturated trifluoromethyl ketones
2015
[EN] The conjugate diynylation of a,b-unsaturated trifluoromethyl ketones is carried out in the presence of a low catalytic load (2.5 mol%) of a copper(I)–MeOBIPHEP complex, triethylamine and a terminal 1,3-diyne. Pre-metalation of the terminal 1,3-diyne with stoichiometric or higher amounts of dialkylzinc reagent is not required. The corresponding internal diynes bearing a propargylic stereogenic center are obtained with good yields and excellent enantioselectivities.
Un museo de ciencia accesible a la sociedad. Contribución e impacto
2022
El conocimiento es objeto de investigación y discusión; la ciudadanía lo utiliza de manera crítica transformándolo en herramientas que les permiten mejorar su vida a nivel individual y colectivo. Las diferencias sociales y jerárquicas que históricamente determinaban el acceso al capital formativo se han difuminado en el último siglo, y cada vez más se consume una gran variedad de formas de cultura, independientemente del nivel social, económico o cultural. Entre los centros culturales más visitados por los y las ciudadanas encontramos los museos. Estos núcleos de conocimiento trabajan para que su finalidad comunicativa esté en sintonía con los contenidos que ofrecen y tratan de dar respuest…
Bases genéticas y celulares de neuropatías periféricas hereditarias
2015
Tesis doctoral; 208 págs.