Search results for "IIN"
showing 10 items of 1385 documents
Leisure-time cross-country skiing is associated with lower incidence of hypertension:A prospective cohort study
2019
Abstract Objective: The prospective relationship between cross-country skiing and hypertension is uncertain. We aimed to assess the associations of leisure time cross-country skiing habits with incident hypertension in a general population. Methods: The frequency, average duration, and intensity of leisure cross-country skiing were assessed at baseline using a 12-month physical activity questionnaire in the Kuopio Ischemic Heart Disease prospective study of 1809 middle-aged men without hypertension. Hazard ratios [95% confidence intervals (CIs)] were calculated. Results: New onset diagnosis of hypertension was observed in 279 participants during a median (interquartile range) follow-up of 2…
Effects of Aerodynamic Drag and Drafting on Propulsive Force and Oxygen Consumption in Double Poling Cross-country Skiing
2022
Purpose To investigate the effects of aerodynamic drag and drafting on propulsive force (FPROP), drag area (CDA), oxygen cost (V˙O2), metabolic rate (E˙) and heart rate (HR) during roller skiing on a treadmill in a wind tunnel using the double poling technique. A secondary aim was to investigate the effects of wind versus no-wind test conditions on the same physiological parameters. Methods 10 subjects of each gender participated in the experiments. One pair of skiers of the same gender roller skied simultaneously in line with the air flow; the distance between the skiers was ~2.05 m. Each pair was tested as follows: I) with wind, leading; II) with wind, drafting; III) without wind. The tre…
Prevention of chemotherapy‐induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle
2017
Background Toxicity of chemotherapy on skeletal muscles and the heart may significantly contribute to cancer cachexia, mortality, and decreased quality of life. Doxorubicin (DOX) is an effective cytostatic agent, which unfortunately has toxic effects on many healthy tissues. Blocking of activin receptor type IIB (ACVR2B) ligands is an often used strategy to prevent skeletal muscle loss, but its effects on the heart are relatively unknown. Methods The effects of DOX treatment with or without pre-treatment with soluble ACVR2B-Fc (sACVR2B-Fc) were investigated. The mice were randomly assigned into one of the three groups: (1) vehicle (PBS)-treated controls, (2) DOX-treated mice (DOX), and (3) …
Changes in performance and poling kinetics during cross-country sprint skiing competition using the double-poling technique
2013
In this study, changes in skiing performance and poling kinetics during a simulated cross-country sprint skiing competition were investigated. Twelve elite male cross-country skiers performed simulated sprint competition (4 x 1,150 m heat with 20 min recovery between the heats) using the double-poling technique. Vertical and horizontal pole forces and cycle characteristics were measured using a force plate system (20-m long) during the starting spurt, racing speed, and finishing spurt of each heat. Moreover, heat and 20-m phase velocities were determined. Vertical and horizontal pole impulses as well as mean cycle length were calculated. The velocities of heats decreased by 2.7 +/- 1.7% (p …
Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DAL…
2014
The aims of this study were to describe the variability in protein binding of teicoplanin in critically ill patients as well as the number of patients achieving therapeutic target concentrations. This report is part of the multinational pharmacokinetic DALI Study. Patients were sampled on a single day, with blood samples taken both at the midpoint and the end of the dosing interval. Total and unbound teicoplanin concentrations were assayed using validated chromatographic methods. The lower therapeutic range of teicoplanin was defined as total trough concentrations from 10 to 20 mg/L and the higher range as 10-30 mg/L. Thirteen critically ill patients were available for analysis. The followi…
Canon vs. charisma : "Maoism" as an ideological construction
2006
Mao Zedongin (1893–1976) poliittinen ja ideologinen perintö on tutkimuksellisesti jälleen ajankohtainen, kolmekymmentä vuotta ”suuren ruorimiehen” kuoleman jälkeen. Maoa on kuvattu milloin puhdasoppiseksi marxilaiseksi, milloin kiinalaiseksi patriootiksi. Maoismin tutkimuksessa on usein keskusteltu siitä, missä määrin Mao seurasi perinteisiä marxilaisia oppeja ja missä määrin hän taas sisällytti kiinalaisia elementtejä omaan ideologiseen tulkintaansa. Viime aikoina julkisuuteen tulleet historiantulkinnat sen sijaan pyrkivät osoittamaan, että Mao oli vain tunteeton ja väkivaltaan taipuvainen itsevaltias.Kauppinen esittää väitöstyössään, että Maon ideologisen maailmankatsomuksen kannalta ei o…
On Martial Law at 50 : Fact-Checking the Marcos Story, Countering the EDSA History
2022
To fact-check and counter the historical denialism of the Marcos family, there is need for a counterfactual history analysis of the failings of the 1986 EDSA People Power Revolution. nonPeerReviewed
El Capitan as a Site for Male Healing from Trauma in Jeff Long’s The Wall and Tommy Caldwell’s The Push
2019
Nature and mountains are often represented as places of healing in literature and the media, especially for white, healthy, and middleclass men. However, discussions on nature and gender in relation to trauma are rare, and a specific discussion on the representation of male mountain climbers’ traumas is missing. In this article, we are interested in how nature, particularly the famous mountain El Capitan, is represented in Jeff Long’s novel “The Wall” (2006) and Tommy Caldwell’s memoir “The Push” (2017) as a specific spatial location of healing for male rock climbers, who at the same time are both victims of traumatic events and partially responsible for the development of those events. Mor…
Light absorption and electrical transport in Si:O alloys for photovoltaics
2010
Thin films (100-500 nm) of the Si:O alloy have been systematically characterized in the optical absorption and electrical transport behavior, by varying the Si content from 43 up to 100 at. %. Magnetron sputtering or plasma enhanced chemical vapor deposition have been used for the Si:O alloy deposition, followed by annealing up to 1250 °C. Boron implantation (30 keV, 3-30× 1014 B/cm2) on selected samples was performed to vary the electrical sheet resistance measured by the four-point collinear probe method. Transmittance and reflectance spectra have been extracted and combined to estimate the absorption spectra and the optical band gap, by means of the Tauc analysis. Raman spectroscopy was …
SERS activity of photoreduced silver chloride crystals
2019
Metal nanoparticles are widely acclaimed as plasmonic substrates for surface -enhanced Raman spectroscopy (SERS) due to their unique particle plasmon resonances at visible and near infrared regions. Silver nanoparticles are typically employed in SERS when the targeted Raman signature zone of analytes lies at ultra-violet and/or blue to green spectral regimes. Even though silver has strong plasmonic properties, silver-based substrates are often affected by the atmospheric oxidation and show degradation in their SERS performance. One way to overcome this limitation is to use silver chloride crystals as oxidation resistant intermediate and photoreduce them to 'fresh' silver just before SERS an…