Search results for "ILLNESS"
showing 10 items of 1529 documents
RISK ANALISYS REGARDING HEALTH AND SAFETY AT WORK
2018
The work was created according to the provisions of the work safety legislation in force, regarding the obligation of the management of the economic agents to correctly determine the risk factors in order to ensure the measures for prevention of accidents and professional illnesses. The analysis presents the main aspects of the frequent mistakes that may arise in the risk assessment. So, it has been concluded that risks are inevitable in business, and that each activity is unique, as well as the risks from one activity to another or from one group of activities to another. Under these circumstances, it has been established that the success of an enterprise depends on how the risks were mana…
Noninvasive Ventilation in Critically Ill Patients
2015
Since its first application in the late 1980s, noninvasive ventilation (NIV) has been the first-line intervention for certain forms of acute respiratory failure. NIV may be delivered through the patient's mouth, nose, or both using noninvasive intermittent positive pressure ventilation or continuous positive airway pressure. When applied appropriately, NIV may reduce morbidity and mortality and may avert iatrogenic complications and infections associated with invasive mechanical ventilation. This article provides physicians and respiratory therapists with a comprehensive, practical guideline for using NIV in critical care. © 2015 Elsevier Inc.
Spousal support and illness acceptance in breast cancer patients: the mediating function of meaning in life and sense of coherence
2023
The explanation as to why married cancer patients are characterised by better adjustment to illness than unmarried patients is not fully understood. This article aims to investigate a parallel mediation effect of meaning in life and sense of coherence in the relationship of spousal support and illness acceptance in breast cancer patients. A total of 213 women were included in this study. The Berlin Social Support Scales, the Personal Meaning Profile, the Sense of Coherence Scale, and the Acceptance of Life with the Disease Scale were used. Pearson’s correlation coefficient and mediation analysis were performed. The results showed significant correlations between spousal support, meaning in…
Influence of Resilience and Optimism on Distress and Intention to Self-Isolate: Contrasting Lower and Higher COVID-19 Illness Risk Samples From an Ex…
2021
The study investigated the influence of resilience and dispositional optimism on, first, emotional distress and, second, the intention to self-isolate, experienced by people with a lower and higher illness risk, during the lockdown imposed in Spain during the first COVID-19 wave. These effects were investigated against the background of the Health Belief Model (HBM). A convenience sample of N = 325 participants completed an online survey including an ad-hoc questionnaire measuring the HBM core factors: Perceived health threat (susceptibility and severity of getting infected), and perceived quarantine benefits and costs. Self-efficacy and perceived social pressure were also measured. Based o…
Illness Narrative and Self-Help Culture – Self-Help Writing on Age-Related Infertility
2014
Both self-help books and illness narratives are motivated by an impulse to overcome a crisis and, simultaneously, to help others who suffer from similar conditions. In doing so, authors of self-help and illness narratives move in between polar opposites: they have both individual and collective motives, they have a desire to overcome uncertainty and achieve control and they negotiate the authority of experience versus the authority of expertise. This paper has two objectives: (1) It describes the intersections of illness life writing and self-help culture and traces the thematic, cultural and historical similarities. (2) It analyzes a selection of four autobiographical, U.S.-American self-h…
Severe asthma at COVID-19 time: what is new on biologic therapies.
2021
Antithrombotic Therapy in COVID-19: Systematic Summary of Ongoing or Completed Randomized Trials
2021
ABSTRACTEndothelial injury and microvascular/macrovascular thrombosis are common pathophysiologic features of coronavirus disease-2019 (COVID-19). However, the optimal thromboprophylactic regimens remain unknown across the spectrum of illness severity of COVID-19. A variety of antithrombotic agents, doses and durations of therapy are being assessed in ongoing randomized controlled trials (RCTs) that focus on outpatients, hospitalized patients in medical wards, and critically-ill patients with COVID-19. This manuscript provides a perspective of the ongoing or completed RCTs related to antithrombotic strategies used in COVID-19, the opportunities and challenges for the clinical trial enterpri…
COVID-19 lockdown influence in the psychiatric emergencies: Drastic reduction and increase in severe mental disorders.
2021
Burden of illness of progressive familial intrahepatic cholestasis in the US, UK, France, and Germany: study rationale and protocol of the PICTURE st…
2021
Background: Progressive familial intrahepatic cholestasis (PFIC) is an ultra-rare disease with a considerable burden on pediatric patients and their caregivers, impacting quality of life (QoL). The mortality rates highlight a significant need for efficacious treatments. Real-world data on associated costs and QoL are needed to gauge the potential impact of new pharmacological treatments. Methods: Clinical and socio-economic burden of PFIC on patients/caregivers, health systems, and society will be assessed. Patient/caregiver- and physician-level retrospective cross-sectional data will be collected from the US, UK, France, and Germany, for PFIC types 1, 2, 3. A representative sample of physi…
The Evolution of Hemophilia Care: Clinical and Laboratory Advances, Opportunities, and Challenges
2020
AbstractHemophilia A (HA) and B (HB) are X-linked bleeding disorders caused by mutations in the F8 or F9 gene that result in the absence, or reduced activity, of the corresponding clotting factor. The severity of bleeding and related complications is proportional to the amount of residual circulating functional factor. The development of a safe and effective hemophilia treatment lasted several decades and has been mainly based on clotting factor replacement. Advances in the engineering and manufacturing of clotting concentrates have led to the widespread availability of extended half-life products that reduced the number of intravenous infusions needed to achieve adequate trough levels. The…