Search results for "INCIDENCE"

showing 10 items of 2270 documents

Diabetic foot ulcers: Retrospective comparative analysis from Sicily between two eras

2021

Aim The aim of this study was to analyze changes in the incidence, management and mortality of DFU in Sicilian Type 2 diabetic patients hospitalized between two eras, i.e. 2008–2013 and 2014–2019. Methods We compared the two eras, era1: 2008–13, era2: 2014–19. In era 1, n = 149, and in era 2, n = 181 patients were retrospectively enrolled. Results In the population hospitalized for DFU in 2008–2013, 59.1% of males and 40.9% of females died, whilst in 2014–2019 65.9% of males and 34.1% of females died. Moderate chronic kidney disease (CKD) was significantly higher in patients that had died than in ones that were alive (33% vs. 43%, p < 0.001), just as CKD was severe (14.5% vs. 4%, p <…

MaleComorbidityAntiplatelet TherapyBiochemistrySettore MED/13 - EndocrinologiaEndocrinologyMedical ConditionsOral DiseasesRetrospective StudieChronic Kidney DiseaseMedicine and Health SciencesSurgical AmputationInsulinSicilyUlcersAged 80 and overMultidisciplinaryPharmaceuticsIncidenceQRMiddle AgedDiabetic FootType 2 DiabetesHospitalizationNephrologyMedicineFemaleHumanResearch ArticleEndocrine DisordersScienceOral MedicineSurgical and Invasive Medical ProceduresSigns and SymptomsLife ExpectancyDrug TherapyDiabetes MellitusRenal DiseasesHumansMortalityRenal Insufficiency ChronicAgedRetrospective StudiesDiabetic EndocrinologyBiology and Life SciencesHormonesDiabetes Mellitus Type 2Metabolic DisordersClinical MedicinePLoS ONE
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Hypertensive status and lipoprotein oxidation in an elderly population at high cardiovascular risk.

2008

BACKGROUND: In elderly individuals, hypertension is a main risk factor for cardiovascular disease and oxidative damage is increased. Our aim was to assess the relationship between the degree of in vivo low-density lipoprotein (oxLDL) oxidation and the hypertensive status in a elderly population at high cardiovascular risk. METHODS: Cross-sectional study with baseline data from the PREDIMED (PREvención con DIeta MEDiterránea) trial, an intervention study directed at testing the efficacy of the Mediterranean diet on the primary prevention of cardiovascular disease. Participants were 1,130 subjects at high cardiovascular risk aged 55-80. At baseline, in vivo circulating oxLDL was measured, and…

MaleCoronary DiseaseDiet MediterraneanSeverity of Illness IndexRisk groupsRisk FactorsMedicineAged 80 and overCoronary diseaseBioquímica y tecnologíaIncidence0895-7061Follow up studiesAge FactorsMiddle AgedPrognosisBiochemistry and technologyHypertensionChristian ministrylipids (amino acids peptides and proteins)HipertensióFemaleHypertensive StatusLypoproteinsmedicine.medical_specialtyLipoproteinsLipid peroxidationEnzyme-Linked Immunosorbent AssayBioquímica i biotecnologiaEnvironmental healthElderly populationInternal medicineInternal MedicineHumansLipoprotein oxidationLipoprotein OxidationAgedRetrospective Studiesbusiness.industryLipoproteïnes -- OxidacióUnited StatesPersones grans -- NutricióElderly PopulationOxidative StressEndocrinologyCross-Sectional StudiesMulticenter studyOxidative stressHypertension complicationsLipid PeroxidationbusinessOlive oilFollow-Up StudiesAmerican journal of hypertension
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Global, regional, and national burden of stroke, 1990-2016

2019

Background: Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016. Methods: We report estimates and corresponding uncertainty intervals (UIs), from 1990 to 2016, for incidence, preval…

MaleCost effectivenessIMPACTGlobal HealthGUIDELINES3124 Neurology and psychiatryBrain IschemiaGlobal Burden of DiseaseCOST-EFFECTIVENESS0302 clinical medicineRisk FactorsGlobal healthPrevalenceMedicine030212 general & internal medicineStrokePOPULATIONAged 80 and overRISKeducation.field_of_studyIncidence (epidemiology)Mortality rateIncidenceAge FactorsMiddle AgedPREVALENCEStrokeFemaleLife Sciences & BiomedicineIntracranial HemorrhagesAdultPopulationClinical Neurology03 medical and health sciencesHumanseducationAgedScience & TechnologyNeurology & Neurosurgerybusiness.industry3112 NeurosciencesKlinisk medicin1103 Clinical Sciencesmedicine.diseaseGBD 2016 Stroke CollaboratorsVerbal autopsyTRANSIENT ISCHEMIC ATTACKYears of potential life lostSocioeconomic FactorsHuman medicineNeurosciences & NeurologyNeurology (clinical)Clinical Medicine1109 NeurosciencesbusinessPRIMARY PREVENTION030217 neurology & neurosurgeryDemographyRCLancet Neurology
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Spinopelvic changes based on the simplified SRS-Schwab adult spinal deformity classification: relationships with disability and health-related qualit…

2018

Study design Cross-sectional, observational study. Objective To study the occurrence of sagittal malalignment, the adaptability of a simplified sagittal modifiers grading of the Scoliosis Research Society (SRS)-Schwab adult spinal deformity (ASD) classification, and the deformity-specific SRS questionnaire version 30 (SRS-30) in an unselected adult cohort with symptomatic degenerative spinal disorders. Summary of background data The sagittal modifiers of the SRS-Schwab ASD classification correlate with health-related quality of life (HRQoL) measures in patients with ASD. The deformities and disabilities caused by sagittal malalignment in patients with common degenerative spinal disorders of…

MaleCross-sectional studypelvic tiltelämänlaatuODICohort StudiesDisability Evaluation0302 clinical medicineQuality of lifeSurveys and QuestionnairesOrthopedics and Sports Medicinetoimintarajoitteet030222 orthopedicssagittal alignmentpelvic incidenceta3141Middle AgedOswestry Disability IndexHRQOLdegenerative spinal disordermedicine.anatomical_structureScoliosisCohortsagittal vertical axisFemaleSpinal Diseasesmedicine.symptomCohort studyAdultmedicine.medical_specialtyT1 Pelvic AngleScoliosis03 medical and health sciencesselkäsairaudetparasitic diseasesmedicineDeformityHumansSRS-30Agedbusiness.industrySRS-Schwab classificationadult spinal deformitylumbar lordosismedicine.diseaseSagittal planeCross-Sectional Studiessagittal modifierQuality of LifePhysical therapyNeurology (clinical)business030217 neurology & neurosurgery
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Changing geographical patterns and trends in cancer incidence in children and adolescents in Europe, 1991–2010 (Automated Childhood Cancer Informatio…

2018

List of ACCIS contributors = Monika Hackl, Anna Zborovskaya, Nadya Dimitrova, Zdravka Valerianova, Ladislav Dušek, Margit Mägi, Alain Monnereau, Jacqueline Clavel, Michel Velten, Anne-Valérie Guizard, Véronique Bouvier, Xavier Troussard, Anne-Sophie Woronoff, Emilie Marrer, Brigitte Trétarre, Marc Colonna, Olivier Ganry, Pascale Grosclaude, Berndt Holleczek, Zsuzsanna Jakab, Laufey Tryggvadóttir, Lucia Mangone, Franco Merletti, Stefano Ferretti, Bianca Caruso, Maria Michiara, Rosario Tumino, Fabio Falcini, Roberto Zanetti, Giovanna Tagliabue, Otto Visser, Giske Ursin, Ryszard Mężyk, Kamila Kepska, José Laranja Pontes, Maja Primic Žakelj, Rafael Fernández-Delgado, Marisa L Vicente Raneda, En…

MaleCàncer en els infantsTime FactorsCancer in children0302 clinical medicineRisk FactorsNeoplasms030212 general & internal medicineRegistriesAge of OnsetChildmedia_commoneducation.field_of_studyCancer in adolescenceIncidence (epidemiology)Incidence3. Good healthEuropeOncology030220 oncology & carcinogenesisRegional studiesChild PreschoolFemale2730 OncologyAdolescentPopulationChildhood cancerSocio-culturale610 Medicine & healthRisk AssessmentArticle03 medical and health sciencesYoung AdultAge DistributionSDG 3 - Good Health and Well-beingmedicinemedia_common.cataloged_instanceHumansCàncer en els adolescentsEuropean unioneducationbusiness.industryInfant NewbornCancerInfantHealth Status Disparities10060 Epidemiology Biostatistics and Prevention Institute (EBPI)medicine.diseasePopulation based studyCancer incidencebusinessDemography
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Incidence, risk factors, clinical characteristics and outcomes of deep venous thrombosis in patients with COVID-19 attending the Emergency Department…

2021

Background and importance A higher incidence of venous thromboembolism [both pulmonary embolism and deep vein thrombosis (DVT)] in patients with coronavirus disease 2019 (COVID-19) has been described. But little is known about the true frequency of DVT in patients who attend emergency department (ED) and are diagnosed with COVID-19. Objective We investigated the incidence, risk factors, clinical characteristics and outcomes of DVT in patients with COVID-19 attending the ED before hospitalization. Methods We retrospectively reviewed all COVID patients diagnosed with DVT in 62 Spanish EDs (20% of Spanish EDs, case group) during the first 2 months of the COVID-19 outbreak. We compared DVT-COVI…

MaleDeep veinComorbidity030204 cardiovascular system & hematologyChest pain0302 clinical medicineRisk Factorsrisk factorsclinical characteristicsIncidenceIncidence (epidemiology)Age FactorsVenous ThromboembolismMiddle AgedPulmonary embolismVenous thrombosismedicine.anatomical_structureEmergency MedicineoutcomeFemalemedicine.symptomEmergency Service Hospitalsevere acute respiratory syndrome coronavirus 2Adultmedicine.medical_specialtyRisk Assessment03 medical and health sciencescoronavirus disease 2019Internal medicineThromboembolismmedicineHumanscardiovascular diseasesTromboembolismeAgedRetrospective Studiesdeep venous thrombosisbusiness.industryCOVID-19030208 emergency & critical care medicineRetrospective cohort studyOriginal ArticlesEmergency departmentOdds ratiomedicine.diseaseSpainCase-Control StudiesincidencePulmonary Embolismbusiness
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Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately …

2017

Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50–75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2–3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and…

MaleDiabetes and Metabolism ipoglycemic drugs cardiovascualr eventSettore MED/09 - Medicina Internaendocrine system diseasesIMPACTpioglitazone versus sulfonylureasEndocrinology Diabetes and MetabolismGLIMEPIRIDEDiabetes cardiovascular events metformin pioglitazone sulphonylureasType 2 diabetes030204 cardiovascular system & hematologyInternal Medicine; Endocrinology Diabetes and Metabolism; Endocrinologylaw.inventionSettore MED/13 - EndocrinologiaGlibenclamide0302 clinical medicineRandomized controlled triallawGLYCEMIC CONTROLGliclazideInternal medicinediabetes and metabolismRISKeducation.field_of_studydiabetesIncidenceInternal medicine; endocrinology diabetes and metabolism; endocrinologyMiddle AgedINSULINMetforminMetforminTreatment OutcomeEditorialsulphonylureasCardiovascular DiseasesCombinationDrug Therapy CombinationFemaleType 2medicine.drugmedicine.medical_specialtyPopulation030209 endocrinology & metabolismAged; Cardiovascular Diseases; Diabetes Mellitus Type 2; Drug Therapy Combination; Female; Humans; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Pioglitazone; Sulfonylurea Compounds; Thiazolidinediones; Treatment OutcomeCardiovascular events03 medical and health sciencesendocrinologyGLUCOSE-LOWERING DRUGSDrug TherapyInternal medicineDiabetes MellitusmedicineHumansHypoglycemic AgentssulfonylureaseducationTOSCA.ITAgedPioglitazonebusiness.industryMORTALITYnutritional and metabolic diseasesInsulin resistancemedicine.diseaseSurgeryGlimepirideSulfonylurea CompoundsDiabetes Mellitus Type 2Diabetes Mellitus; Pioglitazone; Insulin resistanceThiazolidinedionesbusinessFOLLOW-UPPioglitazone
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Egg consumption and cardiovascular disease according to diabetic status: The PREDIMED study.

2015

BACKGROUND: Eggs are a major source of dietary cholesterol and their consumption has been sometimes discouraged. A relationship between egg consumption and the incidence of cardiovascular disease (CVD) has been suggested to be present exclusively among patients with type2 diabetes. AIMS: To assess the association between egg consumption and CVD in a large Mediterranean cohort where approximately 50% of participants had type 2 diabetes. METHODS: We prospectively followed 7216 participants (55-80 years old) at high cardiovascular risk from the PREDIMED (PREvención con DIeta MEDiterránea) study for a mean of 5.8 years. All participants were initially free of CVD. Yearly repeated measurements o…

MaleDiabetic CardiomyopathiesEggsHealth StatusSistema cardiovascular -- MalaltiesType 2 diabetes030204 cardiovascular system & hematologyCritical Care and Intensive Care MedicineDiet MediterraneanCohort Studies0302 clinical medicineRisk FactorsDiet Diabetic030212 general & internal medicineProspective StudiesProspective cohort studyDiet Fat-RestrictedAged 80 and overOusNutrition and DieteticsDiabetisMediterranean RegionIncidence (epidemiology)IncidenceHazard ratioDiabetesMiddle AgedCardiovascular diseaseCardiovascular DiseasesCohortFemaleCohort studymedicine.medical_specialty03 medical and health sciencesDiabetes mellitusInternal medicinemedicineHumansEgg consumptionAgedProportional Hazards ModelsProportional hazards modelbusiness.industryPREDIMED studymedicine.diseaseEndocrinologyDiabetes Mellitus Type 2Patient ComplianceSelf ReportbusinessDiabetic AngiopathiesFollow-Up Studies
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The association between new onset atrial fibrillation and incident cancer—A nationwide cohort study

2018

A recent analysis showed an association with new onset atrial fibrillation (NOAF) and incident cancer among women. We aimed to examine the risk of cancer among patients with NOAF in general population. A retrospective cohort of 5130 patients with NOAF was identified from a random sample of one million subjects between 2005 and 2010 from Taiwan National Health Insurance Research Database. The standard incidence ratio of incident cancer and hazard ratios were calculated by modeling cumulative incidence with competing risk of death. During a mean follow-up duration of 3.4 years, 330 patients developed cancer. The standard incidence ratio of all malignancies was 1.41 (95% confidence interval 1.…

MaleEconomicslcsh:MedicineSocial Sciences030204 cardiovascular system & hematologyVascular MedicineBrain Ischemia0302 clinical medicineRisk FactorsNeoplasmsEpidemiology of cancerAtrial FibrillationMedicine and Health SciencesGenitourinary CancersCumulative incidence030212 general & internal medicinelcsh:ScienceAged 80 and overeducation.field_of_studyMultidisciplinaryCancer Risk FactorsIncidenceHazard ratioAge FactorsMiddle AgedStrokeOncologyNeurologyFemaleArrhythmiaCohort studyResearch Articlemedicine.medical_specialtyCerebrovascular DiseasesUrologyPopulationCardiology03 medical and health sciencesBreast cancerHealth EconomicsSex FactorsDiagnostic MedicineInternal medicinemedicineCancer Detection and DiagnosisHumanseducationIschemic StrokeAgedColorectal Cancerbusiness.industrylcsh:RCancerCancers and NeoplasmsRetrospective cohort studymedicine.diseaseHealth CareWomen's Healthlcsh:QbusinessHealth InsuranceFollow-Up StudiesPLoS ONE
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Childhood central nervous system tumours – incidence and survival in Europe (1978–1997): Report from Automated Childhood Cancer Information System pr…

2006

Abstract This paper describes the incidence and survival of childhood central nervous system (CNS) tumours in Europe for the period 1978–1997. A total of 19,531 cases, aged 0–14 years, from the ACCIS database were analysed by five regions: the British Isles, East, North, South, and West. Overall age-standardised incidence rate (ASR) of CNS tumours in Europe (1988–1997) was 29.9 per million, with the highest rates in the North. Astrocytoma (ASR = 11.8), primitive neuroectodermal tumours (PNET) (ASR = 6.5) and ependymoma (ASR = 3.4) were the most frequent types. Incidence increased significantly during 1978–1997, on average by 1.7% per year. Diagnostic methods may partially explain incidence …

MaleEpendymomaCancer Researchmedicine.medical_specialtyAdolescentDatabases FactualChildhood cancerCentral nervous systemCentral Nervous System NeoplasmsEpidemiologymedicineHumansRegistriesChildcentral nervous system tumoursbusiness.industryIncidenceIncidence (epidemiology)Infant NewbornInfantChildhood cancers - survival - time trends; central nervous system tumoursAstrocytomaCancermedicine.diseaseSurvival AnalysisSurgeryEuropemedicine.anatomical_structureOncologyEl NiñoChild PreschoolFemalebusinessChildhood cancers - survival - time trendsDemographyEuropean Journal of Cancer
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