Search results for "INFORMATICS"

showing 10 items of 2542 documents

The EU-project United4Health: User-centred design of an information system for a Norwegian telemedicine service.

2015

Introduction Organizational changes of health care services in Norway brought to light a need for new clinical pathways. This study presents the design and evaluation of an information system for a new telemedicine service for chronic obstructive pulmonary disease patients after hospital discharge. Methods A user-centred design approach was employed composed of a workshop with end-users, two user tests and a field trial. For data collection, qualitative methods such as observations, semi-structured interviews and a questionnaire were used. Results User workshop’s outcome informed the implementation of the system initial prototype, evaluated by end-users in a usability laboratory. Several us…

TelemedicineProcess management020205 medical informaticsHealth Informatics02 engineering and technologycomputer.software_genreHealth informaticsEducationInterviews as Topic03 medical and health sciencesHealth Information SystemsPulmonary Disease Chronic ObstructiveUser-Computer Interface0302 clinical medicineUser experience designSoftware DesignHeuristic evaluationSurveys and QuestionnairesHealth care0202 electrical engineering electronic engineering information engineeringInformation systemmedia_common.cataloged_instanceHumans030212 general & internal medicineEuropean UnionEuropean unionmedia_commonService (business)Multimediabusiness.industryNorwayTelemedicinebusinesscomputerJournal of telemedicine and telecare
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Telemedicine: Economic and clinical evaluation of the management of ischemic stroke

2017

Summary Introduction Ischemic stroke (IS) is a therapeutic emergency that requires prompt care in a stroke unit (SU). In order to reduce regional inequalities and to promote uniformity in access to this technique, which is effective when carried out quickly, telemedicine-assisted thrombolysis was developed in Burgundy within the Telestroke system. At the moment, no study compared costs (i.e. expenditures) and revenues (i.e. funding) associated with the management of patients presenting an IS in Burgundy after the implementation of the Telestroke system according to the management strategy: patients undergoing thrombolysis directly in a SU or Tele-thrombolysis in a local hospital (LH) receiv…

Telemedicinebusiness.industrymedicine.medical_treatmentHealth InformaticsThrombolysismedicine.disease03 medical and health sciences0302 clinical medicineHealth Information ManagementHealth careEconomic evaluationIschemic strokeMedicineEconomic analysisObservational study030212 general & internal medicineMedical emergencybusinessClinical evaluation030217 neurology & neurosurgeryEuropean Research in Telemedicine / La Recherche Européenne en Télémédecine
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Changes in telepsychiatry regulations during the COVID-19 pandemic: 17 countries and regions' approaches to an evolving healthcare landscape

2020

Author(s): Kinoshita, Shotaro; Cortright, Kelley; Crawford, Allison; Mizuno, Yuya; Yoshida, Kazunari; Hilty, Donald; Guinart, Daniel; Torous, John; Correll, Christoph U; Castle, David J; Rocha, Deyvis; Yang, Yuan; Xiang, Yu-Tao; Kolbaek, Pernille; Dines, David; ElShami, Mohammad; Jain, Prakhar; Kallivayalil, Roy; Solmi, Marco; Favaro, Angela; Veronese, Nicola; Seedat, Soraya; Shin, Sangho; Salazar de Pablo, Gonzalo; Chang, Chun-Hung; Su, Kuan-Pin; Karas, Hakan; Kane, John M; Yellowlees, Peter; Kishimoto, Taishiro | Abstract: BackgroundDuring the COVID-19 pandemic, the use of telemedicine as a way to reduce COVID-19 infections was noted and consequently deregulated. However, the degree of te…

Telemedicinehealth insurance reimbursement020205 medical informaticsCOVID-19 government regulation health insurance reimbursement telemedicine telepsychiatrytelepsychiatry02 engineering and technologyPublic administration03 medical and health sciences0302 clinical medicineClinical ResearchPolitical sciencePandemicHealth careGlobal network0202 electrical engineering electronic engineering information engineeringPsychology030212 general & internal medicineApplied PsychologyReimbursementPsychiatrygovernment regulationbusiness.industryTelepsychiatryNeurosciencesCOVID-19Health ServicesPsychiatry and Mental healthGood Health and Well BeingSnowball samplingScale (social sciences)COVID-19; government regulation; health insurance reimbursement; telemedicine; telepsychiatryPublic Health and Health ServicesOriginal ArticletelemedicinebusinessPsychological Medicine
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Could telemedicine enhance traditional medicine practices?

2014

International audience; In developing countries, telemedicine and mobile health tools promise to enhance access to high-quality healthcare, to support communication of medical information and to assist pharmacovigilance processes. In this article, we provide some arguments on the potential of telemedicine and mobile health (mHealth) applications to improve the delivery of health care in rural African regions. Specifically, the development of mobile telemedicine could help to lay the foundations of a healthcare approach integrating modern medical knowledge with ancient medical practices on the African continent. Access to information and communication technology (ICT), technical devices or p…

Telemedicinemedicine.medical_specialtyAlternative medicineDeveloping countryMédecine humaine et pathologieHealth InformaticsContext (language use)Developing countriesHealth Information Management[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyPharmacovigilanceHealth careMedicineMobile healthmHealth[ INFO.INFO-ET ] Computer Science [cs]/Emerging Technologies [cs.ET]Traditional medicinebusiness.industryTechnologies ÉmergeantesTherapeutic educationIntegrated health centerTelemedicine3. Good healthInformation and Communications Technology[INFO.INFO-ET]Computer Science [cs]/Emerging Technologies [cs.ET]businessComplementary medicine[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells.

2014

This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.

TelomeraseDNA repairDNA damagelcsh:MedicineCell Cycle ProteinsComputingMilieux_LEGALASPECTSOFCOMPUTINGBiologyTransfectionBioinformaticsmedicine.disease_causeBiochemistryDyskeratosis CongenitaDyskerinCell LineMiceHeterochromatinMolecular Cell BiologyMedicine and Health SciencesmedicineAnimalsHumanslcsh:ScienceMutationMultidisciplinarylcsh:RBiology and Life SciencesNuclear ProteinsCell BiologyHematologyGenetic TherapyTransfectionTelomeremedicine.diseaseTelomereCell biologyOxidative StressGene Expression Regulationlcsh:QPeptidesDyskeratosis congenitaResearch ArticleDNA DamagePLoS ONE
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snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis

2013

AbstractAmplification of the MYCN oncogene is strongly associated with poor prognosis in neuroblastoma (NB). In addition to MYCN amplification, many studies have focused on identifying patients with a poor prognosis based on gene expression profiling. The majority of prognostic signatures today are comprised of large gene lists limiting their clinical application. In addition, although of prognostic significance,most of these signatures fail to identify cellular processes that can explain their relation to prognosis. Here, we determined prognostically predictive genes in a data set containing 251 NBs. Gene Ontology analysis was performed on significant genes with a positive hazard ratio to …

TelomeraseGene knockdownCancer ResearchBiologyBioinformaticsTelomereGene expression profilingOncologyChromosome instabilityCancer researchSmall nucleolar RNAGeneRibonucleoproteinResearch Article
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tert-Butyl N-benzyl-N-[4-(4-fluorobenzoylmethyl)-2-pyridyl]carbamate

2008

In the crystal structure of the title compound, C25H25FN2O3, the pyridine ring makes dihedral angles of 75.1 (3), 39.4 (3) and 74.6 (3)° with the phenyl ring, the carbamate plane and the 4-fluorophenyl ring, respectively. The phenyl ring makes dihedral angles of 77.2 (3) and 23.6 (3)° with the carbamate plane and the 4-fluorophenyl ring, respectively. The 4-fluorophenyl ring is perpendicular to the carbamate plane, the dihedral angle between them being 89.5 (3)°.

Tert butylCarbamateCrystallographymedicine.medical_treatmentGeneral ChemistryCrystal structureDihedral angleCondensed Matter PhysicsRing (chemistry)BioinformaticsOrganic PapersMedicinal chemistrychemistry.chemical_compoundchemistryQD901-999PyridinemedicineGeneral Materials ScienceActa Crystallographica Section E
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tert-ButylN-(4-methyl-2-pyridyl)carbamate

2008

The crystal structure of the title compound, C11H16N2O2, contains two crystallographically independent molecules forming dimers by pairs of intermolecular N—H...N hydrogen bonds. The two molecules are related by a pseudo-twofold axis. The dihedral angle between the pyridine ring and the carbamate plane differs in the two molecules [12.1 (3) and 3.5 (3)°].

Tert butylCarbamateHydrogen bondChemistrymedicine.medical_treatmentGeneral ChemistryCrystal structureDihedral angleCondensed Matter PhysicsBioinformaticsRing (chemistry)Organic PapersMedicinal chemistrylcsh:Chemistrychemistry.chemical_compoundlcsh:QD1-999PyridinemedicineGeneral Materials ScienceActa Crystallographica Section E Structure Reports Online
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tert-Butyl N-benzyl-N-(4-methyl-2-pyrid­yl)carbamate

2008

In the crystal structure of the title compound, C18H22N2O2, the pyridine ring makes dihedral angles of 83.71 (6) and 9.2 (1)° with the phenyl ring and the carbamate plane, respectively. The phenyl ring and the carbamate plane are nearly perpendicular to one another, with a dihedral angle of 87.17 (7)°.

Tert butylCarbamateMathematics::Commutative AlgebraChemistrymedicine.medical_treatmentGeneral ChemistryCrystal structureDihedral angleCondensed Matter PhysicsRing (chemistry)BioinformaticsMedicinal chemistryOrganic Paperslcsh:Chemistrychemistry.chemical_compoundlcsh:QD1-999PyridinePerpendicularmedicineGeneral Materials ScienceActa Crystallographica Section E: Structure Reports Online
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2,4-Di-tert-butyl-6-({[2-(di-methyl-amino)-eth-yl](2-hy-droxy-benz-yl)amino}-meth-yl)phenol.

2014

The title compound, C26H40N2O2, has both its N atoms in trigonal-pyramidal geometries. The molecular structure is stabilized by O—H...N and C—H...O hydrogen bonds. In the crystal, C—H...π interactions lead to the formation of a supramolecular helical chain along theb-axis direction.

Tert butylQuantitative Biology::BiomoleculesCrystallographyChemistryHydrogen bondSupramolecular chemistryGeneral ChemistryMeth-Condensed Matter PhysicsBioinformaticsMedicinal chemistryOrganic PapersHelical chainchemistry.chemical_compoundQD901-999PhenolGeneral Materials ScienceActa crystallographica. Section E, Structure reports online
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