Search results for "INFORMATICS"

showing 10 items of 2542 documents

Escala de percepción ante crisis y pandemias : desarrollo y validación de una escala pedagógica

2021

Objetivos: Abordar la metodología de estudio con respecto a epidemia/pandemia requiere involucrar pensamiento complejo frente a los retos que denota esta situación. El objetivo de este estudio es validar un cuestionario de percepción y creencias dirigido a estudiantes de medicina y enfermería sobre el uso del cine ante la complejidad de un evento pandémico, con el propósito de potenciar las estrategias de enseñanza. Metodología: Se encuestó a 131 estudiantes. La evaluación de la confiabilidad se realizó a través del análisis de consistencia interna. La valoración de los 19 ítems se evaluó mediante análisis de correlación de Pearson y la validez de constructo mediante análisis factorial expl…

03 medical and health sciences0302 clinical medicine020205 medical informatics0202 electrical engineering electronic engineering information engineeringMedicina Ensenyament030212 general & internal medicine02 engineering and technologyGeneral MedicineEpidemiologiaSalut pública PlanificacióEducation
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What is science without replication?

2016

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03 medical and health sciences0302 clinical medicine020205 medical informaticsReplication (statistics)Commentary0202 electrical engineering electronic engineering information engineering030212 general & internal medicine02 engineering and technologyComputational biologyPsychologyEducationPerspectives on Medical Education
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Stakeholder Contradictions in Early Stages of eHealth Efforts

2017

03 medical and health sciences0302 clinical medicine020205 medical informaticsbusiness.industryLocal government0202 electrical engineering electronic engineering information engineeringStakeholdereHealth030212 general & internal medicine02 engineering and technologyBusinessPublic relationsStakeholder theoryProceedings of the 50th Hawaii International Conference on System Sciences (2017)
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Télémédecine et accident vasculaire cérébral : étude de coût sur la téléfibrinolyse

2016

Resume Introduction L’accident vasculaire cerebral ischemique (AVCi) est une urgence therapeutique qui necessite une prise en charge rapide par fibrinolyse au sein d’unites neurovasculaires (UNV) sous la surveillance d’un medecin specialise en neurologie. Il n’existe que deux UNV en Bourgogne (France). Afin de diminuer les inegalites territoriales et favoriser l’equite d’acces a cette technique efficace si realisee precocement, la fibrinolyse assistee par telemedecine a ete developpees en Bourgogne dans le cadre du projet TeleAVC. A ce jour, aucune etude n’a evalue avec precision le cout des actes de fibrinolyse ou fibrinolyse par telemedecine dans ce dispositif. L’objectif de cette etude e…

03 medical and health sciences0302 clinical medicineHealth Information ManagementPolitical scienceIschemic strokeHealth Informatics030212 general & internal medicineHumanities030217 neurology & neurosurgeryEuropean Research in Telemedicine / La Recherche Européenne en Télémédecine
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Tendencia de la población española de búsqueda en internet sobre información relacionada con diferentes dietas

2020

Resumen Objetivo Explorar a traves Google Trends las tendencias del interes de la poblacion espanola sobre informacion relacionada con diferentes tipos de dietas, focalizadas en las mas populares y con estudios de evidencia, a lo largo de los ultimos 10 anos. Material y metodo Se analizaron las tendencias de busqueda de los terminos «dieta mediterranea», «dieta cetogenica», «dieta baja en grasas», «ayuno intermitente» y «dieta vegana». El volumen relativo de busqueda (VRB) de cada termino fue comparado. La direccion de la tendencia se estudio mediante la correlacion de Spearman (CS). Resultados El termino «dieta mediterranea» fue el mas buscado, con una mediana de VRB de 16 (rango intercuar…

03 medical and health sciences0302 clinical medicineNutrition and DieteticsEndocrinology020205 medical informaticsEndocrinology Diabetes and Metabolism0202 electrical engineering electronic engineering information engineering030212 general & internal medicine02 engineering and technologyEndocrinología, Diabetes y Nutrición
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Taste Disturbance with Acetazolamide

1997

03 medical and health sciences0302 clinical medicinebusiness.industrymedicineMEDLINEPharmacology (medical)030204 cardiovascular system & hematologyAcetazolamidebusinessBioinformatics030226 pharmacology & pharmacymedicine.drugTaste disturbanceAnnals of Pharmacotherapy
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Human tear metabolome

2016

0301 basic medicine03 medical and health sciences030104 developmental biology0302 clinical medicinebusiness.industry030221 ophthalmology & optometryMetabolomeMedicineTearsGeneral MedicinebusinessBioinformaticsArchivos de la Sociedad Española de Oftalmología (English Edition)
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2016

AbstractMulticellular tumor spheroids (MCTSs) embedded in a matrix are re-emerging as a powerful alternative to monolayer-based cultures. The primary information gained from a three-dimensional model is the invasiveness of treatment-exposed MCTSs through the acquisition of light microscopy images. The amount and complexity of the acquired data and the bias arisen by their manual analysis are disadvantages calling for an automated, high-throughput analysis. We present a universal algorithm we developed with the scope of being robust enough to handle images of various qualities and various invasion profiles. The novelty and strength of our algorithm lie in: the introduction of a multi-step se…

0301 basic medicine03 medical and health sciencesMulticellular organism030104 developmental biologyMultidisciplinaryGentamicin protection assayTumor spheroidSegmentationBiologyBiological systemBioinformaticsScientific Reports
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Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR).

2018

Betulinic acid (BetA) is a naturally occurring pentacyclic triterpene isolated from the outer bark of white-barked birch trees and many other medicinal plants. Here, we studied betulinic acid's cytotoxic activity against drug-resistant tumor cell lines. P-glycoprotein (MDR1/ABCB1) and BCRP (ABCG2) are known ATP-binding cassette (ABC) drug transporters that mediating MDR. ABCB5 is a close relative to ABCB1, which also mediates MDR. Constitutive activation of the EGF receptor is tightly linked to the development of chemotherapeutic resistance. BetA inhibited P-gp, BCRP, ABCB5 and mutation activated EGFR overexpressing cells with similar efficacy as their drug-sensitive parental counterparts. …

0301 basic medicine03 medical and health scienceschemistry.chemical_compound0302 clinical medicineBetulinic acidCytotoxic T cellcancerPharmacology (medical)ReceptorCell adhesionOriginal ResearchPharmacologypharmacogenomicsdrug resistancelcsh:RM1-950ABCB5phytotherapybioinformaticsCell cycleMultiple drug resistance030104 developmental biologylcsh:Therapeutics. Pharmacologychemistry030220 oncology & carcinogenesistriterpeneCancer researchautocrine motility factor receptor (AMFR)Signal transductionmicroarrayFrontiers in pharmacology
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Exploring the human microbiome from multiple perspectives: factors altering its composition and function

2017

Abstract Our microbiota presents peculiarities and characteristics that may be altered by multiple factors. The degree and consequences of these alterations depend on the nature, strength and duration of the perturbations as well as the structure and stability of each microbiota. The aim of this review is to sketch a very broad picture of the factors commonly influencing different body sites, and which have been associated with alterations in the human microbiota in terms of composition and function. To do so, first, a graphical representation of bacterial, fungal and archaeal genera reveals possible associations among genera affected by different factors. Then, the revision of sequence-bas…

0301 basic medicine030106 microbiologyPopulation structuremicrobiomeReview ArticleBiologyBioinformaticsMicrobiology03 medical and health sciencesMetabolomicsmedicineHumansMicrobiomeComposition (language)MicrobiotaHuman microbiomeRepresentation (systemics)dysbiosisBiodiversitymedicine.diseasemetabolomicsomics030104 developmental biologyInfectious DiseasesEvolutionary biologyMetabolomegutDysbiosisFunction (biology)FEMS Microbiology Reviews
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