Search results for "INR"

showing 10 items of 184 documents

L'INRA prépare activement l'agriculture de demain

2018

National audience

[SDE] Environmental Sciencesagroécologie[SDE]Environmental SciencesINRA Dijonplateforme CA-SYSComputingMilieux_MISCELLANEOUSzero pesticidevulgarisation
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Suomen ulkomaankaupan kasvu 1600-1800 -luvuilla : juutinrauman tullitilien uudelleenarviointi

2018

Työn tavoite on yhtenäistää Juutinrauman tullitiliaineistoja ja arvioida tullitilien käytettävyyttä Suomen ulkomaankaupan tutkimuksessa. Yhtenäistettyjen aikasarjojen pohjalta voidaan myös tarkastella Suomen – aikaisempaan tutkimukseen verrattuna pidemmän – pitkän aikavälin ulkomaankaupan kehitystä. Työssä rakennetaan uusi Suomea koskeva tietokanta FIN-STRO. Taustateoriana on siten lähtökohtaisesti ankkuroitua teoriaa (aineistopohjainen teoria, grounded theory) muistuttava lähestymistapa. Tutkimus hyödyntää Juutinrauman tullitilejä, joita laadittiin v. 1497–1857. Tutkimus koskee Suomen ulkomaankauppaa v. 1557–1856, jolloin suomalaisia satamia on kirjattu lähtösatamiksi Juutinrauman tullitil…

tuontivientiulkomaankauppatullitilittullitJuutinrauma1600-luku1700-luku1800-luku
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Puuttuvuuden mallintaminen FINRISKI-tutkimuksessa

2017

Puuttuva tieto on ongelma terveystutkimuksissa, koska tutkimukseen osallistujat ja ei-osallistujat usein eroavat toisistaan. Puuttuvuuden mallintaminen on tärkeää, jotta tuloksia pystyttäisiin korjaamaan ja jatkossa ottamaan mallinnettu puuttuvuus paremmin huomioon tutkimusta suunnitellessa. Myös Kansallinen FINRISKI-tutkimus kärsii puuttuvuudesta, sillä tutkimuksen osallistumisprosentti on laskenut jatkuvasti. Tutkimus on Terveyden ja hyvinvoinnin laitoksen väestötutkimussarja, jonka tavoitteena on seurata kansantauteja ja niiden riskitekijöitä Suomessa sekä tarkkailla suomalaisten terveydentilaa. Tässä työssä pyritään mallintamaan Kansallisen FINRISKI-tutkimuksen puuttuvuus tarkastelemall…

yleistetyt additiiviset mallitkolmannen asteen tasoitussplinelokaali pisteytysalgoritmitilastomenetelmätyleistetty logistinen regressioFINRISKI -tutkimusikä-periodi-kohortti -analyysitasoitusfunktiotakaisinsovitusalgoritmi
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IL-1 BLOCKADE IN PAEDIATRIC RECURRENT PERICARDITIS: A MULTICENTRIC RETROSPECTIVE STUDY OF THE ITALIAN COHORT

2019

Introduction: Acute pericarditis is an inflammatory condition causing the occurrence of pericardial effusion. In a third of patients, the disease is recurrent. First line treatment of idiopathic pericarditis consists in non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine; glucocorticoids represent the second line treatment in resistant or intolerant cases. A recent clinical trial has enlightened the effectiveness of anakinra in adults and paediatric patients with colchicine-resistant recurrent pericarditis. Objectives: To describe the clinical characteristics and response to treatment in a cohort of paediatric patients with recurrent pericarditis treated with IL inhibitors. Method…

Settore MED/38 - Pediatria Generale E SpecialisticaRecurrent pericarditis Anakinra Colchicine-resistence Canakinumab
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New design and simulation of the ion guide for neutron-induced fission products at the IGISOL facility

2023

Measurements of independent fission yield distributions in neutron-induced fission at high neutron energies are important for our fundamental understanding of the fission process, and are also relevant for reactor physics applications. So far, measurements of independent fission yields in proton-induced fission have been performed at the IGISOL facility at the University of Jyväskylä, using the Penning trap as a high resolving-power mass-filter. In order to also facilitate measurements of neutron-induced fission, a dedicated ion guide and a proton-to-neutron converter was developed. However, the first measurement indicates that fewer fission products than expected reach the Penning trap. To…

Subatomär fysikfissioCOMSOLydinreaktiotionitiimulationSubatomic Physicsion guideneutronitNeutron-induced fissionydinfysiikkaGEANT4electric field
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Penning-trap mass measurements on 92, 94-98, 100Mo with JYFLTRAP

2012

Penning-trap measurements on stable 92, 94-98, 100Mo isotopes have been performed with relative accuracy of \ensuremath1⋅10−8\ensuremath1⋅10−8 with the JYFLTRAP Penning-trap mass spectrometer by using 85Rb as a reference. The Mo isotopes have been found to be about 3keV more bound than given in the Atomic Mass Evaluation 2003 (AME03). The results confirm that the discrepancy between the ISOLTRAP and JYFLTRAP data for 101-105Cd isotopes was due to an erroneous value in the AME03 for 96Mo used as a reference at JYFLTRAP. The measured frequency ratios of Mo isotopes have been used to update mass-excess values of 30 neutron-deficient nuclides measured at JYFLTRAP. peerReviewed

nuclear spectroscopyPhysicsNuclear and High Energy PhysicsMass excessIsotopeaccelerator-based physicsPenning trapMass spectrometrykiihdytinpohjainen fysiikkaISOLTRAPAtomic massNuclear physicsydinrakennenuclear structureydinspektroskopiaNuclear fusionNuclideAtomic physicsydinfysiikkaThe European Physical Journal A
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Istutuspäällikkö Gaddin julkiset matkaraportit 1763–1765

2022

Artikkelissa tarkastellaan Inrikes Tidningarissa julkaistuja raportteja Pehr Adrian Gaddin (1727–1797) matkoista Suomessa vuosina 1763–1765. Tekstit sekä rikastavat käsitystä Gaddin toiminnasta istutuspäällikkönä että antavat esimerkin mahdollisesta julkisuuden käytöstä vapaudenajan lopun Ruotsissa.

Gadd Pehr AdriantiedonvälitysVertaisarviodut artikkelit - Referentgranskade artiklar1760-lukuSatakuntahenkilöhistoriaInrikes TidningarLounais-Suomivalistuksen aikaGeneral MedicineRuotsilehdistökirjoitteluvirkamiehetmaatalousmaataloushallintohyödyn aikakausimatkakertomuksetsanomalehdetjulkisuusAURAICA. Scripta a Societate Porthan edita
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Telemedicine-Based Specialized Care Improves the Outcome of Anticoagulated Individuals with Venous Thromboembolism-Results from the thrombEVAL Study.

2020

Venous thromboembolism (VTE) is a life-threatening disease with risk of recurrence. Oral anticoagulation (OAC) with vitamin K antagonists (VKA) is effective to prevent thromboembolic recurrence. We aimed to investigate the quality of OAC of VTE patients in regular medical care (RMC) compared to a telemedicine-based coagulation service (CS). The thrombEVAL study (NCT01809015) is a prospective, multi-center study to investigate OAC treatment (recruitment: January 2011&ndash

medicine.medical_specialtyANTITHROMBOTIC THERAPYPULMONARY-EMBOLISMvenous thromboembolismlcsh:Medicine030204 cardiovascular system & hematologyRate ratioWARFARINArticle03 medical and health sciences0302 clinical medicineInterquartile rangeInternal medicinemedicineORAL ANTICOAGULATION030212 general & internal medicineAdverse effectcoagulation serviceINR CONTROLNORMALIZED RATIO CONTROLPRACTICAL MANAGEMENTbusiness.industrySTROKE PREVENTIONlcsh:RHazard ratioWarfarinAtrial fibrillationGeneral Medicinemedicine.diseaseConfidence intervalMEDICAL-CAREPulmonary embolismvitamin K antagonistsATRIAL-FIBRILLATIONe-healthbusinessoral anticoagulation therapymedicine.drugJournal of clinical medicine
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First isomeric yield ratio measurements by direct ion counting and implications for the angular momentum of the primary fission fragments

2018

We report the first experimental determination of independent isomeric yield ratios using direct ion counting with a Penning trap, which offered such a high resolution in mass that isomeric states could be separated. The measurements were performed at the Ion Guide Isotope Separator On-Line (IGISOL) facility at the University of Jyvaskyla. The isomer production ratios of Ge-81, Y-96,Y-97 Sn-128(,1)30, and Sb-129 in the 25-MeV proton-induced fission of U-na(t) and Th-232 were studied. Three isomeric pairs (Ge-81, Y-96, and Sb-129) were measured for the first time for the U-na(t)(p, f) reaction, while all the reported yield ratios for the Th-232(p, f) reaction were determined for the first ti…

Angular momentumResolution (mass spectrometry)Fission01 natural sciencesIonSubatomär fysikydinreaktiotPrimary (astronomy)0103 physical sciencesSubatomic PhysicsPhysics::Atomic and Molecular ClustersfissionYield ratioPhysics::Atomic PhysicsPhysics::Chemical PhysicsNuclear Experiment010306 general physicsnuclear reactionsPhysicsta114010308 nuclear & particles physicsPenning trapfissioYield (chemistry)Atomic physicsisomer decaysydinfysiikka
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Anakinra drug retention rate and predictive factors of long-term response in systemic juvenile idiopathic arthritis and adult onset still disease

2019

Background and Objective: Only a few studies have reported long-term efficacy of interleukin (IL)-1 inhibition in systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still disease (AOSD). Herein we report on the effectiveness of anakinra (ANA), expressed in terms of drug retention rate (DRR), and evaluate the predictive factors of drug survival in a cohort of patients with sJIA and AOSD. Patients and Methods: This is a multicenter study reviewing retrospectively the medical records from 61 patients with sJIA and 76 with AOSD, all treated with ANA in 25 Italian tertiary referral centers. Results: The cumulative retention rate of ANA at 12-, 24-, 48-, and 60-month of follow-up was 7…

0301 basic medicineAdult onset Still diseasemedicine.medical_specialtyArthritisStill DiseaseAdult onset Still disease; Anakinra; Drug retention rate; Innovative biotechnologies; Interleukin 1-beta; Personalized medicine; Systemic juvenile idiopathic arthritis03 medical and health sciences0302 clinical medicineSettore MED/38 - Pediatria Generale E Specialisticaanakinra interleukin 1-beta innovative biotechnologies drug retention rate systemic juvenile idiopathic arthritis adult onset Still disease personalized medicineSystemic juvenile idiopathic arthritisInternal medicinemedicinePharmacology (medical)Adverse effectOriginal ResearchPharmacologyAnakinrabusiness.industryHazard ratiolcsh:RM1-950Innovative biotechnologiesmedicine.diseaseDrug retention ratePersonalized medicineConfidence intervalAdult onset Still disease Anakinra Drug retention rate Innovative biotechnologies Interleukin 1-beta Personalized medicine Systemic juvenile idiopathic arthritisDiscontinuation030104 developmental biologylcsh:Therapeutics. PharmacologyAnakinraInnovative biotechnologie030220 oncology & carcinogenesisCohortInterleukin 1-betabusinessmedicine.drug
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